Bioactive Compounds and Functional Properties of Herbal Preparations of Cystus creticus L. Collected From Rhodes Island.
2022
Аутори:
Mocan, AndreiFernandes, Ângela
Calhelha, Ricardo C.
Gavrilaş, Laura
Ferreira, Isabel C. F. R.
Ivanov, Marija
Soković, Marina
Barros, Lillian
Babotă, Mihai
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
The members of Cystus genus are perenial shrubs with a well-established use in traditional medicine. Among these, C. creticus is the most popular, herbal preparations obtained from its aerial parts being recognized as antimicrobial, antitumor and anti-inflammatory agents. The present study aimed to evaluate phytochemical profile and bioactive potential of aqueous and hydroethanolic extracts of C. creticus aerial parts harvested from two different areas of Rhodes island. LC-DAD-ESI/MSn analysis revealed the presence of myricetin and quercetin glycosides as main compounds, especially in aqueous extracts, being probably responsible for their enhanced antioxidant and antimicrobial potential. On the other side, hydroethanolic preparations exerted a strong anti-inflammatory and anti-biofilm activity. Our findings suggest that the use of solvents with intermediate polarity can assure the best recovery of bioactive compounds from C. creticus, increasing the extraction yield for other non-phenolic compounds which can enhance therapeutic potential of the extract through a synergistic action.
Кључне речи:
Cystus creticus; Antimicrobial compounds; Bioactive compounds; Herbal preparations; Natural antioxidantИзвор:
Frontiers in Nutrition, 2022, 9, 881210-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-200007)
- Consiliul National al Cercetarii Stiintifice (CNCS) Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii (UEFISCDI)
DOI: 10.3389/fnut.2022.881210
ISSN: 2296-861X
PubMed: 35677542
WoS: 000807205400001
[ Google Scholar ]URI
https://www.frontiersin.org/articles/10.3389/fnut.2022.881210/fullhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC9168797
http://radar.ibiss.bg.ac.rs/handle/123456789/5006