Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
2023
Аутори:
Đurović, SašaPezo, Lato
Gašić, Uroš
Gorjanović, Stanislava
Pastor, Ferenc
Bazarnova, Julia G.
Smyatskaya, Yulia A.
Zeković, Zoran
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant's popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r2 value during the training cycle for output variables was 0.999).
Кључне речи:
ANN modeling; HPLC-DAD-MS/MS; biological activity; exhausted plant material; polyphenolic profile; stinging nettle leavesИзвор:
Foods (Basel, Switzerland), 2023, 12, 4, 809-Финансирање / пројекти:
- Ministry of Education and Science of the Russian Federation
DOI: 10.3390/foods12040809
ISSN: 2304-8158
PubMed: 36832884
Scopus: 2-s2.0-85148859369
URI
https://www.mdpi.com/2304-8158/12/4/809http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC9957156
http://radar.ibiss.bg.ac.rs/handle/123456789/5492