dc.contributor | Pešić, Vladimir | |
dc.contributor | Hadžiablahović, Sead | |
dc.creator | Dinić, Svetlana | |
dc.creator | Arambašić Jovanović, Jelena | |
dc.creator | Bogojević, Desanka | |
dc.creator | Grdović, Nevena | |
dc.creator | Grigorov, Ilijana | |
dc.creator | Ivanović-Matić, Svetlana | |
dc.creator | Labus-Blagojević, Svetlana | |
dc.creator | Martinović, Vesna | |
dc.creator | Mihailović, Mirjana | |
dc.creator | Petrović, Miodrag | |
dc.creator | Uskoković, Aleksandra | |
dc.creator | Vidaković, Melita | |
dc.creator | Poznanović, Goran | |
dc.date.accessioned | 2023-05-18T11:15:07Z | |
dc.date.available | 2023-05-18T11:15:07Z | |
dc.date.issued | 2006 | |
dc.identifier.isbn | 86-908743-1-3 | |
dc.identifier.uri | http://radar.ibiss.bg.ac.rs/handle/123456789/5636 | |
dc.description.abstract | CYP1A is a well-established biomarker of fish exposure to xenobiotics. Polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) are ubiquitous environmental pollutants in the aquatic environment. They induce a dose-dependent transcriptional induction of CYP1A genes and resulting increased concentrations of proteins. Our aim was to characterize the ecological impact of chemical contaminants in view of their toxicological potential. For that reasons the relative changes of CYP1A concentrations in the hepatopancreas of the Red mullet-Mullus barbatus, European hake-Merluccius merluccius and Tub gurnard-Trigla lucerna were examined in spring, at the mouth of the river Bojana. All species are of considerable commercial importance. In this work chemical analysis of seawater was performed and CYP1A induction was estimated by immunoblot analysis. Chemical analyses of seawater and sediment revealed the presence of anthracene, benzo(A)pyrene, pcb28 and pcb101. CYP1A was detected in the hepatic microsomal fraction in all examined fish species as an adaptive response to the slightly increased concentrations of PAHs and PCBs. It was shown in this study that CYP1A is a sensitive biomarker demonstrating that pollutants entered the organisms and elicited toxic effects at the critical target(s). The apparent initiation of the defense response in fish suggests that the contaminants present in seawater have an ecotoxicological potential. These findings could be interpreted as an early-warning signal for the deleterious effects of the pollutants. | sr |
dc.language.iso | en | sr |
dc.publisher | Podgorica: Centre for Biodiversity of Montenegro | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/143002/RS// | sr |
dc.rights | openAccess | sr |
dc.source | The Book of Abstracts and Programme: II International Symposium of Ecologists of Montenegro ISEM2; 2006 Sep 20-24; Kotor, Montenegro | sr |
dc.title | The expression of CYP1A in the hepatopanceas of analysed fish species at the mouth of the river Bojana | sr |
dc.type | conferenceObject | sr |
dc.rights.license | ARR | sr |
dc.rights.holder | © 2006 by the Centre for Biodiversity of Montenegro | sr |
dc.description.other | Pešić V, Hadžiablahović S, editors. The Book of Abstracts and Programme: II International Symposium of Ecologists of Montenegro ISEM2; 2006 Sep 20-24; Kotor, Montenegro. Podgorica: Centre for Biodiversity of Montenegro; 2006. p. 115. | sr |
dc.citation.spage | 115 | |
dc.type.version | publishedVersion | sr |
dc.identifier.cobiss | 10640656 | |
dc.identifier.fulltext | https://radar.ibiss.bg.ac.rs/bitstream/id/12272/bitstream_12272.pdf | |
dc.citation.rank | M34 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_ibiss_5636 | |