Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials
2021
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Authors:
Pergal, MarijaBrkljačić, Jelena
Tovilović-Kovačević, Gordana
Špirkova, Milena
Kodranov, Igor
Manojlović, Dragan
Knežević, Nenad
Contributors
Čupić, ŽeljkoAnić, Slobodan
Document Type:
Conference object (Published version)
,
© 2021 by the Society of Physical Chemists of Serbia
Metadata
Show full item recordAbstract:
Surface characteristics and biocompatibility of new nanocomposites based on polyurethane network
and mesoporous silica nanoparticles (PUMSNs) were investigated. Surface topography and
roughness coefficient were studied by AFM. Biocompatibility with endothelial cells and cytotoxicity
of the PUNs were assessed using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium
bromide) and cell adhesion assays. The addition of MSNs into polyurethane network led to
improvement of surface properties, as well as exhibited promising characteristics regarding adhesion
of cells, toward potential application in coating for medical devices.
Keywords:
nanocomposites; polyurethane network; mesoporous silica nanoparticles; endothelial cell adhesion; biocompatibilityFunding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) (RS-MESTD-inst-2020-200026)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200358 (BioSense Institute) (RS-MESTD-inst-2020-200358)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200168 (University of Belgrade, Faculty of Chemistry) (RS-MESTD-inst-2020-200168)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
- Serbian-French Bilateral Project No. 337-00-8/2020- 04 (2020-2021)
- Czech Science Foundation (No: 18-03932S)
In:
- Čupić Ž, Anić S, editors. Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia. Belgrade: Society of Physical Chemists of Serbia; 2021. p. 480-2.
URI
http://www.socphyschemserb.org/sr/publikacije/http://radar.ibiss.bg.ac.rs/handle/123456789/5732