Bioaccumulation and effects of metals on oxidative stress and neurotoxicity parameters in the frogs from the Pelophylax esculentus complex
2016
Autori:
Prokić, MarkoBorković-Mitić, Slavica
Krizmanić, Imre
Mutić, Jelena
Trifković, Jelena
Gavrić, Jelena
Despotović, Svetlana
Gavrilović, Branka
Radovanović, Tijana
Pavlović, Slađan
Saičić, Zorica
Tip dokumenta:
Članak u časopisu (Objavljena verzija)
,
© 2016, Springer Science Business Media New York
Metapodaci
Prikaz svih podataka o dokumentuApstrakt:
Metals are involved in the formation of reactive
oxygen species and can induce oxidative stress. The aim of
this study was to assess the effects of several metals on
oxidative stress in the skin and muscle of the Pelophylax
esculentus “complex” frogs (parental species Pelophylax
ridibundus, Pelophylax lessonae, and their hybrid Pelophylax esculentus) that inhabit the wetland Obedska Bara in
Serbia, and the potential use of these species as bioindicator
organisms in biomonitoring studies. The biomarkers of
oxidative stress (SOD, CAT, GSH-Px, GR, GST activities
and GSH, SH concentrations) and cholinesterase activity
were investigated. The concentrations of nine metals (Fe,
Cu, Zn, As, Cd, Cr, Hg, Ni, and Pb) were measured in the
water and tissues. Correlations were established between
metals and biomarkers in the tissues. The results of metal
accumulation distinguished the skin of P. lessonae and
muscle of P. ridibundus from other P. esculentus complex
species. The oxidative stress biomarkers observed in P.
ridibundus and P. esculentus had greater similarity than in
P. lessonae. The P. lessonae displayed the highest number
of correlations between biomarkers and metals. The results
of tissue responses revealed that skin was more susceptible
to metal-induced oxidative stress, with only exception of
As. In the light of these findings, we can suggest the use of
P. esculentus complex species as a biomonitoring species in
studies of metal accumulation and metal-induced oxidative
stress, but with special emphasis on P. lessonae.
Ključne reči:
Antioxidative defense system; Bioaccumulation; Frogs; Metals; Oxidative stress; Pelophylax esculentus complexIzvor:
Ecotoxicology, 2016, 25, 8, 1531-1542Finansiranje / projekti:
- Molekularno fiziološki biomonitoring aerobnih organizama zasnovan na određivanju biohemijskih biomarkera oksidacionog stresa (RS-MESTD-Basic Research (BR or ON)-173041)
DOI: 10.1007/s10646-016-1707-x
ISSN: 0963-9292
PubMed: 27629268