Biomarkers of oxidative stress in the liver of mediterranean fish, Trigla lucerna from the Adriatic sea
2010
Preuzimanje 🢃
Autori:
Pavlović, SlađanBorković-Mitić, Slavica
Radovanović, Tijana
Gavrilović, Branka
Despotović, Svetlana
Gavrić, Jelena
Saičić, Zorica
Ostala autorstva
Cvijić, GordanaAnđus, Pavle
Nedeljković, Nadežda
Radenović, Lidija
Đorđević, Jelena
Korać, Bato
Tip dokumenta:
Konferencijski prilog (Objavljena verzija)
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© 2010 University of Belgrade, Faculty of Biology
Metapodaci
Prikaz svih podataka o dokumentuApstrakt:
We investigated the effects of season and locality on oxidative stress bio- markers: total, manganese and copper zinc containing superoxide dismutase (Tot SOD, Mn SOD, CuZn SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and phase II biotransformation enzyme glutathione S-transferase (GST) activity in the liver of Tub gurnard (Trigla lucerna) from the Adriatic sea. We also investigated the total protein concentration, as well as electrophoretic profiles of liver proteins. The specimens were collected in winter (February) and spring (May) at localities: Platamuni, Near Bar, Valdanos and Estuary of the River Bojana. The obtained results show significant differences in the activity of oxidative stress biomarkers in the liver of Tub gurnard (Trigla lucerna} between some localities in winter, as well as in spring season. We ob- tained significant seasonal differences for some of investigated parameters also. Our results are most pronounced for phase II biotransformation enzyme glutathi- one S-transferase (GST) activity suggesting that this enzyme is most valuable for this type of biomonitoring studies. Significant changes in total protein concentra- tion between some localities in winter and spring, but without seasonal effects were detected. Our work represents the first study of its kind and suggests that observed changes probably represents physiological adaptation to differences between environmental factors in the sea water, especially in the presence of various concentrations of natural or anthropogenic pollutants.
Ključne reči:
Oxidative stress; Liver; Trigla lucerna; Adriatic seaFinansiranje / projekti:
- Proučavanje poremećaja homeostaze i određivanje biomarkera oksidacionog stresa kod aerobnih organizama (RS-MESTD-MPN2006-2010-143035)
U:
- Cvijić G, Anđus P, Nedeljković N, Radenović L, Đorđević J, Korać B, editors. Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia. Belgrade: University of Belgrade, Faculty of Biology; 2010. p. 111.