Antioxidant defence responses to toxic cyanobacterial bloom in the liver of freshwater fish, Perca fluviatilis from the Gruža reservoir
2010
Аутори:
Gavrilović, BrankaDespotović, Svetlana
Radovanović, Tijana
Gavrić, Jelena
Borković-Mitić, Slavica
Pavlović, Slađan
Ognjanović, Branka
Pajović, Snežana
Saičić, Zorica
Остала ауторства
Cvijić, GordanaAnđus, Pavle
Nedeljković, Nadežda
Radenović, Lidija
Đorđević, Jelena
Korać, Bato
Тип документа:
Конференцијски прилог (Објављена верзија)
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© 2010 University of Belgrade, Faculty of Biology
Метаподаци
Приказ свих података о документуАпстракт:
We investigated alterations of antioxidant defence system (ADS) in the liver of freshwater fish, European perch (Perea fluviatilis) as response to toxic Apha nizomenon flos-aquae bloom in the Gruza Reservoir. Activities of total, manga nese, copper zinc containing superoxide dismutase (Tot SOD, Mn SOD, CuZn SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR), phase II biotransformation enzyme glutathione S-transferase (GST), con centrations of total glutathione (GSH) and sulphydryl (-SH) groups were mea sured before and during bloom period. Histopathological examinations were studied using electron microscopy. Activities of CuZn SOD, CAT and GSH-Px and concentration of -SH groups were significantly lower, while Mn SOD activ ity was significantly higher during bloom period. No differences were observed for Tot SOD, GR and GST activities, as well as for GSH concentration. Electron microscopy showed alterations in hepatocytes, which results in damage of cells. Our work represents the first study of its kind and suggest on influence of toxic Aphanizomenon flos-aquae bloom in the Gruza Reservoir on ADS and on histo pathological changes in the liver of Perea fiuviatilis indicating on necrotic and apopototic damages of hepatocytes.
Кључне речи:
Oxidative stress; Cyanobacteria; Perca fluviatilis; Gruža reservoirФинансирање / пројекти:
- Проучавање поремећаја хомеостазе и одређивање биомаркера оксидационог стреса код аеробних организама (RS-MESTD-MPN2006-2010-143035)
У:
- Cvijić G, Anđus P, Nedeljković N, Radenović L, Đorđević J, Korać B, editors. Book of Abstracts: International Symposium One hunderd years of Ivan Djajać's (Jean Diaja) Belgrade School of Physiology; 2010 Sep 10-14; Belgrade, Serbia. Belgrade: University of Belgrade, Faculty of Biology; 2010. p. 112.