Hypoglycemic and hypolipidemic effects of Aronia melanocarpa fruit juice in normal rats
2015
Аутори:
Ignjatović, ĐurđicaTovilović-Kovačević, Gordana
Tomić, Mirko
Ranković, Slavica
Popović, Tamara
Debeljak Martačić, Slavica
Glibetić, Marija
Остала ауторства
Uzelac, BrankaТип документа:
Конференцијски прилог (Објављена верзија)
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© 2015 by Serbian Plant Physiology Society
Метаподаци
Приказ свих података о документуАпстракт:
The aim of this study was to assess how the unlimited drinking of Aronia melanocarpa fruit juice, rich in phenolic substances (1.177 g L-¹ gallic acid equivalents), may affect the levels of several biochemical markers in the rat plasma: glucose (Glu), total cholesterol (ChT) and its fractions (HDL and LDL), triglycerides (TG) and transaminases (ALT and AST). Young male rats were being supplied with 3 combinations of juice solutions in drinking water for 34 days, and their blood samples were collected for analysis after animal sacrifices on day 35. The experimental groups contained 20% juice solutions in tap water of: (ARO) 100% master aronia juice, (MIX) 25% master aronia juice + 75% juice reconstruct (without flavonoids), and (PLC) 100% juice reconstruct, and they were compared with a (CTL) control group on pure tap water. Biochemical analyses of plasma on Cobas c-111 analyzer showed a significant 20% decrease of Glu in ARO group in comparison to CTL. ChT was significantly higher in MIX and PLC in relation to both CTL and ARO groups, which arose mainly from LDL elevations. Also, there was a certain (30%), but insignificant increase of TG in MIX and PLC vs. CTL. The effects of aronia on transaminases were registered only for ALT, whose level in ARO was about 3-fold of that in CTL group. In conclusion, everyday free drinking of flavonoid-rich aronia juice solutions appeared to have global hypoglycemic effect in normal rats and, also, certain hypolipidemic effects, when hyperlipidemia was induced probably with higher sugar consumption.
Кључне речи:
Aronia melanocarpa; plasma glucose; plasma lipids; transaminases; ratsФинансирање / пројекти:
- Биолошки механизми, нутритивни унос и статус полинезасићених масних киселина и фолата: Унапређење исхране у Србији (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41030)
У:
- Uzelac B, editor. Book of Abstracts: 2nd International Conference on Plant Biology, 21th Symposium of the Serbian Plant Physiology Society, and CОST Action FA1106 Quality Fruit Workshop; 2015 Jun 17-20; Petnica, Serbia. Belgrade: Serbian Plant Physiology Society: Institute for Biological Research “Siniša Stanković”; 2015. p. 78.