The stimulant behavioral effects of anthocyanin-rich juice of Aronia melanocarpa in rats
2015
Аутори:
Ignjatović, ĐurđicaTovilović-Kovačević, Gordana
Tomić, Mirko
Ranković, Slavica
Popović, Tamara
Debeljak Martačić, Slavica
Glibetić, Marija
Остала ауторства
Uzelac, BrankaТип документа:
Конференцијски прилог (Објављена верзија)
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© 2015 by Serbian Plant Physiology Society
Метаподаци
Приказ свих података о документуАпстракт:
The fruits of Aronia melanocarpa are rich in anthocyanins, plant pigments with a number of registered beneficial effects on human health (e.g. antioxidative, anti-inflammatory, immunomodulatory). Some limited studies have also shown their effects on behavior and cognitive functions in experimental animals. This study was designed to explore the effects of unlimited consumption of diluted aronia juice on rat behavior. Young male Wistar rats were divided into control group (CTL; N=12) with tap water provided ad libitum, and 3 experimental groups (N=8) supplied with drinking solutions of 20% mixtures (m/m) in tap water: (ARO) 100% master aronia juice; (MIX) 25% master aronia juice + 75% placebo solution (juice reconstruct without flavonoids); (PLC) 100% placebo. Rats were being allowed to drink these solutions without limits for 34 days, where on days 31-34 three behavioral tests were performed. These tests revealed that only ARO group exhibited significant behavioral changes: augmented locomotion in an open field test, anxiolytic-like action in elevated plus maze, as well as an increase in active swimming in forced swimming test (which is relevant to antidepressant-like action). These results suggest that everyday drinking of diluted aronia juice (between 6 and 12 g of master aronia juice daily per rat) with high flavonoid content (about 0.12%) for about a month, may induce several stimulant behavioral actions in experimental animals.
Кључне речи:
Aronia melanocarpa; anthocyanins; behavioral tests; behavioral stimulantФинансирање / пројекти:
- Биолошки механизми, нутритивни унос и статус полинезасићених масних киселина и фолата: Унапређење исхране у Србији (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41030)
У:
- Uzelac B, editor. Book of Abstracts: 2nd International Conference on Plant Biology, 21th Symposium of the Serbian Plant Physiology Society, and CОST Action FA1106 Quality Fruit Workshop; 2015 Jun 17-20; Petnica, Serbia. Belgrade: Serbian Plant Physiology Society: Institute for Biological Research “Siniša Stanković”; 2015. p. 78-9.