| dc.description.abstract | Wild mushrooms are mainly collected during the rainy season and valued as a nutritious food and
sources of natural medicines and nutraceuticals. The aim of this study was to determine the chemical
composition and bioactive properties (antioxidant, antimicrobial and cytotoxicity) of Polyporus squa mosus from two different origins, Portugal and Serbia. The sample from Portugal showed higher contents
of as protein (17.14 g/100 g), fat (2.69 g/100 g), ash (3.15 g/100 g) and carbohydrates (77.02 g/100 g); the
same sample gave the highest antioxidant activity: highest reducing power, DPPH radical scavenging
activity, and lipid peroxidation inhibition in both b-carotene/linoleate and TBARS assay. These results
could be related to its higher content in total tocopherols (1968.65 mg/100 g) and phenolic compounds
(1.29 mg/100 g). Both extracts exhibited antibacterial activity against all the tested organisms. The
samples from Serbia gave higher overall antibacterial activity and showed excellent antibiofilm activity
(88.30%). Overall, P. squamosus methanolic extracts possessed antioxidant, antimicrobial, antibiofilm and
anti-quorum sensing activity, and without toxicity for liver cells. This investigation highlights alterna tives to be explored for the treatment of bacterial infections, in particular against Pseudomonas aerugi nosa. This study provides important results for the chemical and bioactive properties, especially
antimicrobial activity of the mushroom P. squamosus. Moreover, to the authors’ knowledge this is the first
report on sugars, organic acids, and individual phenolic compounds in P. squamosus. | sr |
