Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
2016
Аутори:
Mileski, Ksenija S.Ćirić, Ana
Trifunović, Snežana S.
Ristić, Mihailo S.
Soković, Marina
Matevski, Vlado S.
Tešević, Vele V.
Jadranin, Milka B.
Marin, Petar D.
Džamić, Ana M.
Тип документа:
Чланак у часопису (Објављена верзија)
,
© The Royal Society of Chemistry 2016
Метаподаци
Приказ свих података о документуАпстракт:
GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial
parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of
aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl
hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol
extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial
parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the
essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of
Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin,
showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this
study showed the considerable biological potential of H. orphanidis considering free radicals and various
pathogenic strains, including the wild type of P. aeruginosa.
Извор:
Food and Function, 2016, 7, 4061-Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-MESTD-Basic Research (BR or ON)-172053)
- Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (RS-MESTD-Basic Research (BR or ON)-173032)
- Микроморфолошка, фитохемијска и молекуларна истраживања биљака - систематски, еколошки и применљиви аспекти (RS-MESTD-Basic Research (BR or ON)-173029)
Повезане информације:
- Друга верзија
https://radar.ibiss.bg.ac.rs/handle/123456789/6745
DOI: 10.1039/c6fo01018k
ISSN: 2042-6496
PubMed: 27713984