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Efekti akutne hipoksije na energetski status i antioksidacioni zaštitni sistem u krvi šarana - Cyprinus carpio L.
Effects of acute hypoxia on the energy status and antioxidant defense system in the blood of carp - Cyprinvs carpio L.
dc.creator | Žikić, Radoslav V. | |
dc.creator | Štajn, Andraš Š. | |
dc.creator | Pavlović, Slađan | |
dc.creator | Ognjanović, Branka I. | |
dc.creator | Maletić, Snežana D. | |
dc.creator | Marković, Mirjana D. | |
dc.creator | Dragićević-Đoković, Ljiljana M. | |
dc.creator | Radojičić, Ratko M. | |
dc.creator | Saičić, Zorica | |
dc.date.accessioned | 2015-08-28T10:26:51Z | |
dc.date.available | 2015-08-28T10:26:51Z | |
dc.date.issued | 2002 | |
dc.date.issued | 2002 | sr |
dc.identifier.issn | 0354-4664 | sr |
dc.identifier.other | Rad_konverzija_166 | sr |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/85 | |
dc.description.abstract | The influence of acute hypoxia on glucose, pyruvate, lipid peroxide (LP) reduced glutathione (GSH) concentrations and lactate level in the whole blood of carp (Cyprinus carpio L) under aquarium conditions were studied. The activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), the concentrations of ATP and ADP and ATP/ADP ratio in the red blood cells (RBCs) were analyzed. Glutathione-S-transferase (GST) activity was determined in the plasma. Our experiments showed that short-term and long-term hypoxia causes significant changes of all examined haema-tological parameters. Increased concentration of LP and increased SOD CAT and GST activities, as well as a decreased GSH-Px activity showed that under hypoxic conditions oxidative stress and RBCs damage were produced. | en |
dc.description.abstract | Uticaj akutne hipoksije na koncentraciju glukoze, piruvata, lipidnih peroksida (LP), redukovanog glutationa (GSH) i na nivo laktata u krvi šarana (Cyprinu carpio L) je analiziran u akvarijumskim uslovima. U crvenim krvnim zrncima (RBCs) je analizirana aktivnost enzima superoksid-peroksidaze (GSH-Px) kao i koncentracije ATP, ADP i odnos ATP/ADP. U plazmi je analizirana aktivnost glutation S-transferaze (GST). U našim eksperimentima je utvrđeno da kratkotrajna progresivna hipoksija izaziva značajne promene svih ispitivanih hematoloških parametara. Povećanje koncentracije LP i povećanje aktivnosti enzima SOD, CAT i GST uz istovremeno smanjenje aktivnosti GSH-Px potvrđuju nastanak oksidacionog stresa i oštećenje RBCs pod hipoksičnim uslovima. | sr |
dc.description.sponsorship | null | sr |
dc.language.iso | eng | sr |
dc.rights | openAccess | sr |
dc.source | Archives of Biological Sciences | sr |
dc.title | Efekti akutne hipoksije na energetski status i antioksidacioni zaštitni sistem u krvi šarana - Cyprinus carpio L. | sr |
dc.title | Effects of acute hypoxia on the energy status and antioxidant defense system in the blood of carp - Cyprinvs carpio L. | en |
dc.type | article | sr |
dc.rights.license | ARR | |
dcterms.abstract | Штајн, Aндраш Ш.; Жикић, Радослав В.; Радојичић, Ратко М.; Павловић, Слађан З.; Саичић, Зорица; Марковић, Мирјана Д.; Драгићевић-Ђоковић, Љиљана М.; Огњановић, Бранка И.; Малетић, Снежана Д.; | |
dc.citation.issue | 1-2 | sr |
dc.citation.volume | 54 | sr |
dc.citation.spage | 11 | sr |
dc.citation.epage | 18 | sr |
dc.type.version | publishedVersion | sr |
dc.identifier.fulltext | https://radar.ibiss.bg.ac.rs//bitstream/id/1779/Rad_konverzija_166.pdf | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_ibiss_85 |