A Comparative Study of Lactarius Mushrooms: Chemical Characterization, Antibacterial, Antibiofilm, Antioxidant and Cytotoxic Activity
2023
Аутори:
Kostić, MarinaIvanov, Marija
Fernandes, Ângela
Calhelha, Ricardo C.
Glamočlija, Jasmina
Barros, Lillian
Soković, Marina
Ćirić, Ana
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
Mushrooms are valued worldwide for their nutritional, organoleptic and chemical properties. The aim of this study was to determine the chemical composition (free sugars, organic acids, fatty acids, tocopherols and phenolic compounds) and bioactivity of three wild mushrooms (Lactarius piperatus, Lactarius quietus and Lactarius vellereus) from Serbia. Chemical analysis was performed with HPLC-RI and UFLC-PDA (for hydrophilic compounds) and with GC-FID and HPLC-FP (for lipophilic compounds). The analysis of phenolic compounds was performed by UFLC-DAD. Biological activities were evaluated using three different assays (microdilution, TBARS and SRB assays). The results showed that the fruiting bodies were rich in mannitol and trehalose. The main organic acids were oxalic acid and citric acid. As for lipophilic components, stearic, oleic and linoleic acids and β-tocopherol dominated in all the species studied. In addition, the methanolic and ethanolic extracts obtained showed antibacterial, antibiofilm and antioxidant properties. As for cytotoxicity, the extracts were not toxic or only moderately toxic toward different tumor cell lines. According to the results, the selected Serbian mushrooms are a rich source of bioactive compounds, and due to their good biological potential, they can be further exploited as functional ingredients beneficial to human health (antimicrobial agents, antioxidants).
Кључне речи:
Lactarius piperatus; Lactarius quietus; Lactarius vellereus; biofilmИзвор:
Journal of Fungi, 2023, 9, 1, 70-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-MESTD-inst-2020-200007)
- Portuguese Foundation for Science and Technology
- Foundation for Science and Technology (FCT, Portugal) through national funds FCT/MCTES (PIDDAC)
DOI: 10.3390/jof9010070
ISSN: 2309-608X
PubMed: 36675891
WoS: 000917542500001
Scopus: 2-s2.0-85146819509
URI
https://www.mdpi.com/2309-608X/9/1/70http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC9864295
http://radar.ibiss.bg.ac.rs/handle/123456789/5461