Effects of dietary fluoranthene on tissue-specific responses of carboxylesterases, acetylcholinesterase and heat shock protein 70 in two forest lepidopteran species
2023
Authors:
Mrdaković, MarijaFilipović, Aleksandra
Ilijin, Larisa
Grčić, Anja
Matić, Dragana
Vlahović, Milena
Todorović, Dajana
Perić Mataruga, Vesna
Document Type:
Article (Published version)
Metadata
Show full item recordAbstract:
In this study, responses of carboxylesterases, acetylcholinesterase, and stress protein Hsp70 were examined in the midgut and midgut tissue, and brain of fifth instar larvae of Lymantria dispar L. and Euproctis chrysorrhoea L. following chronic exposure to dietary fluoranthene. Specific carboxylesterase activity increased significantly in the midgut tissue of E. chrysorrhoea larvae treated with a lower fluoranthene concentration. The specific patterns of isoforms expression, recorded in larvae of both species, enable efficient carboxylesterase activity as a significant part of defense mechanisms. Increased Hsp70 concentration in the brain of L. dispar larvae points to a response to the proteotoxic effects of a lower fluoranthene concentration. Decreased Hsp70 in the brain of E. chrysorrhoea larvae in both treated groups can suggest induction of other mechanisms of defense. The results indicate the importance of the examined parameters in larvae of both species exposed to the pollutant, as well as
their potential as biomarkers.
Keywords:
Fluoranthene; Lymantria dispar; Euproctis chrysorrhoea; Carboxylesterases; Acetylcholinesterase; Hsp70Source:
Ecotoxicology and Environmental Safety, 2023, 257, 114937-Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
DOI: 10.1016/j.ecoenv.2023.114937
ISSN: 0147-6513