TY  - CONF
AU  - Ranković, Slavica
AU  - Popović, Tamara
AU  - Debeljak Martačić, Jasmina
AU  - Pokimica, Biljana
AU  - Petrović-Oggiano, Gordana
AU  - Tomić, Mirko
AU  - Ignjatović, Đurđica
AU  - Tovilović-Kovačević, Gordana
AU  - Glibetić, Marija
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6770
AB  - Gender related differences in fatty acid composition of different lipid classes are well established. Changes in the proportions of specific long-chain PUFA in membrane phospholipids can alter cell and tissue function.
	The aim of our study was to examine the effects of different diets on phospholipids fatty acids composition in rat's liver of both sexes and to compare them.
	Adult Wistar rats of both sexes (n=8, 300g+5) were used in this study. Animals were fed with different type of diets (standard, fish-based and milk- based). The phospholipids fatty acid composition of liver was determined by Gas Chromatography using Shimadzu GC.
	Diet changes the ratio of SFA, MUFA and PUFA but the effects were sex specific. Milk based diet lowered the amount of SFA (p<0.05) and elevated the ratio of MUFA (ANOVA diet effect, p<0.001) in males (ANOVA sex effect p<0.001, and interaction S x D, p<0.05), and PUFA, in females (ANOVA sex effect p<0.05, and diet effect p<0.05) comparing to standard diet. Milk based diet decreased n-3 (p<0.001), and increased n-6 (p<0.001) and n-6/n-3 (p<0.001) ratio in males comparing to the other type of diets. On the other hand, in females, fish based diet increased n-3 (p<0.001), decreased n-6 (p<0.001) and n-6/n-3 ratio (p<0.001) comparing to standard and milk based diets (ANOVA diet effect, p< 0.001, S x D effect, p<0.001, Tukey's post hoc).
	Our results showed that each type of diet changes the composition of lipids and their ratio in the liver of rats. Fish based diet improving EPA and DHA fatty acid profiles and overall PUFA and has beneficial health effect.
PB  - Belgrade: Serbian Nutrition Society
C3  - Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia
T1  - Effects of different types of diet on liver fatty acids profiles in Wistar rats
SP  - 277
ER  - 

@conference{
author = "Ranković, Slavica and Popović, Tamara and Debeljak Martačić, Jasmina and Pokimica, Biljana and Petrović-Oggiano, Gordana and Tomić, Mirko and Ignjatović, Đurđica and Tovilović-Kovačević, Gordana and Glibetić, Marija",
year = "2016",
abstract = "Gender related differences in fatty acid composition of different lipid classes are well established. Changes in the proportions of specific long-chain PUFA in membrane phospholipids can alter cell and tissue function.
	The aim of our study was to examine the effects of different diets on phospholipids fatty acids composition in rat's liver of both sexes and to compare them.
	Adult Wistar rats of both sexes (n=8, 300g+5) were used in this study. Animals were fed with different type of diets (standard, fish-based and milk- based). The phospholipids fatty acid composition of liver was determined by Gas Chromatography using Shimadzu GC.
	Diet changes the ratio of SFA, MUFA and PUFA but the effects were sex specific. Milk based diet lowered the amount of SFA (p<0.05) and elevated the ratio of MUFA (ANOVA diet effect, p<0.001) in males (ANOVA sex effect p<0.001, and interaction S x D, p<0.05), and PUFA, in females (ANOVA sex effect p<0.05, and diet effect p<0.05) comparing to standard diet. Milk based diet decreased n-3 (p<0.001), and increased n-6 (p<0.001) and n-6/n-3 (p<0.001) ratio in males comparing to the other type of diets. On the other hand, in females, fish based diet increased n-3 (p<0.001), decreased n-6 (p<0.001) and n-6/n-3 ratio (p<0.001) comparing to standard and milk based diets (ANOVA diet effect, p< 0.001, S x D effect, p<0.001, Tukey's post hoc).
	Our results showed that each type of diet changes the composition of lipids and their ratio in the liver of rats. Fish based diet improving EPA and DHA fatty acid profiles and overall PUFA and has beneficial health effect.",
publisher = "Belgrade: Serbian Nutrition Society",
journal = "Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia",
title = "Effects of different types of diet on liver fatty acids profiles in Wistar rats",
pages = "277"
}

Ranković, S., Popović, T., Debeljak Martačić, J., Pokimica, B., Petrović-Oggiano, G., Tomić, M., Ignjatović, Đ., Tovilović-Kovačević, G.,& Glibetić, M.. (2016). Effects of different types of diet on liver fatty acids profiles in Wistar rats. in Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia
Belgrade: Serbian Nutrition Society., 277.

Ranković S, Popović T, Debeljak Martačić J, Pokimica B, Petrović-Oggiano G, Tomić M, Ignjatović Đ, Tovilović-Kovačević G, Glibetić M. Effects of different types of diet on liver fatty acids profiles in Wistar rats. in Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia. 2016;:277..

Ranković, Slavica, Popović, Tamara, Debeljak Martačić, Jasmina, Pokimica, Biljana, Petrović-Oggiano, Gordana, Tomić, Mirko, Ignjatović, Đurđica, Tovilović-Kovačević, Gordana, Glibetić, Marija, "Effects of different types of diet on liver fatty acids profiles in Wistar rats" in Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia (2016):277.

TY  - CONF
AU  - Ranković, Slavica
AU  - Popović, Tamara
AU  - Debeljak Martačić, Jasmina
AU  - Petrović Oggiano, Gordana
AU  - Tomić, Mirko
AU  - Ignjatović, Đurđica
AU  - Tovilović-Kovačević, Gordana
AU  - Miler, Marko
AU  - Glibetić, Marija
PY  - 2015
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6347
AB  - Cardiovascular diseases (CVD) are still leading cause of death worldwide. It has been shown that folic acid deficiency can modify polyunsaturated fatty acid (PUFA) metabolism and thus could contribute to the development of (CVD). The contents of (n-6) and (n-3) long-chain PUFA in cell membranes, are important determinants of the biophysical properties of those membranes. The long-chain n-3 PUFAs have been shown to have beneficial effects in delaying the development of various diseases. The aim of our study was to examine the effects of food enriched with fish flour and/or food enriched with fish flour + folic acid on fatty acid composition of liver lipids in 4 weeks treatment. Fe- male Wistar rats were randomly assigned into 3 experimental groups (n=10, 280g±5). Control group received standard food (Veterinarski zavod, Subotica). Both treated groups received a food enriched with fish flour, while in second treated group folic acid was added. After sacrificing, part of the liver was frozen at -80 °C. The phospholipids fatty acid composition of liver was determined by GC using Shimadzu GC. Our results showed that food enriched with fish flour significantly increased: eicosatrienoic (20:3), eicosapentaenoic acid (20:5), docosapentaenoic acid (22:5), docosahexaenoic acid (22:6), n-3 and decreased arachidonic acid, n-6 and n-6/n-3 ratio of liver phospholipids concentrations vs. control. Food enriched with folic acid increased (20:3), (20:5), (22:5), (22:6), PUFA, n-3 and decreased MUFA and palmitic acid (16:0) and n-6/n-3 ratio vs. control. Both type of food significantly decreased concentration of and linoleic (18:2) and vascenic acid (18:1, n-7).
PB  - Belgrade: Serbian Physiology Society
C3  - Abstract book with final program: Heart Diseases: How New Research May Lead to New Treatments: 2nd European Section Meeting of the International Academy of Cardiovascular Sciences; 2015 Oct 8-10; Belgrade, Serbia
T1  - Effect of omega 3 and folic acid on phospholipids fatty acid composition of liver rats
SP  - 139
EP  - 139
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6347
ER  - 

@conference{
author = "Ranković, Slavica and Popović, Tamara and Debeljak Martačić, Jasmina and Petrović Oggiano, Gordana and Tomić, Mirko and Ignjatović, Đurđica and Tovilović-Kovačević, Gordana and Miler, Marko and Glibetić, Marija",
year = "2015",
abstract = "Cardiovascular diseases (CVD) are still leading cause of death worldwide. It has been shown that folic acid deficiency can modify polyunsaturated fatty acid (PUFA) metabolism and thus could contribute to the development of (CVD). The contents of (n-6) and (n-3) long-chain PUFA in cell membranes, are important determinants of the biophysical properties of those membranes. The long-chain n-3 PUFAs have been shown to have beneficial effects in delaying the development of various diseases. The aim of our study was to examine the effects of food enriched with fish flour and/or food enriched with fish flour + folic acid on fatty acid composition of liver lipids in 4 weeks treatment. Fe- male Wistar rats were randomly assigned into 3 experimental groups (n=10, 280g±5). Control group received standard food (Veterinarski zavod, Subotica). Both treated groups received a food enriched with fish flour, while in second treated group folic acid was added. After sacrificing, part of the liver was frozen at -80 °C. The phospholipids fatty acid composition of liver was determined by GC using Shimadzu GC. Our results showed that food enriched with fish flour significantly increased: eicosatrienoic (20:3), eicosapentaenoic acid (20:5), docosapentaenoic acid (22:5), docosahexaenoic acid (22:6), n-3 and decreased arachidonic acid, n-6 and n-6/n-3 ratio of liver phospholipids concentrations vs. control. Food enriched with folic acid increased (20:3), (20:5), (22:5), (22:6), PUFA, n-3 and decreased MUFA and palmitic acid (16:0) and n-6/n-3 ratio vs. control. Both type of food significantly decreased concentration of and linoleic (18:2) and vascenic acid (18:1, n-7).",
publisher = "Belgrade: Serbian Physiology Society",
journal = "Abstract book with final program: Heart Diseases: How New Research May Lead to New Treatments: 2nd European Section Meeting of the International Academy of Cardiovascular Sciences; 2015 Oct 8-10; Belgrade, Serbia",
title = "Effect of omega 3 and folic acid on phospholipids fatty acid composition of liver rats",
pages = "139-139",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6347"
}

Ranković, S., Popović, T., Debeljak Martačić, J., Petrović Oggiano, G., Tomić, M., Ignjatović, Đ., Tovilović-Kovačević, G., Miler, M.,& Glibetić, M.. (2015). Effect of omega 3 and folic acid on phospholipids fatty acid composition of liver rats. in Abstract book with final program: Heart Diseases: How New Research May Lead to New Treatments: 2nd European Section Meeting of the International Academy of Cardiovascular Sciences; 2015 Oct 8-10; Belgrade, Serbia
Belgrade: Serbian Physiology Society., 139-139.
https://hdl.handle.net/21.15107/rcub_ibiss_6347

Ranković S, Popović T, Debeljak Martačić J, Petrović Oggiano G, Tomić M, Ignjatović Đ, Tovilović-Kovačević G, Miler M, Glibetić M. Effect of omega 3 and folic acid on phospholipids fatty acid composition of liver rats. in Abstract book with final program: Heart Diseases: How New Research May Lead to New Treatments: 2nd European Section Meeting of the International Academy of Cardiovascular Sciences; 2015 Oct 8-10; Belgrade, Serbia. 2015;:139-139.
https://hdl.handle.net/21.15107/rcub_ibiss_6347 .

Ranković, Slavica, Popović, Tamara, Debeljak Martačić, Jasmina, Petrović Oggiano, Gordana, Tomić, Mirko, Ignjatović, Đurđica, Tovilović-Kovačević, Gordana, Miler, Marko, Glibetić, Marija, "Effect of omega 3 and folic acid on phospholipids fatty acid composition of liver rats" in Abstract book with final program: Heart Diseases: How New Research May Lead to New Treatments: 2nd European Section Meeting of the International Academy of Cardiovascular Sciences; 2015 Oct 8-10; Belgrade, Serbia (2015):139-139,
https://hdl.handle.net/21.15107/rcub_ibiss_6347 .