@conference{
author = "Ranković, Slavica and Popović, Tamara and Debeljak Martačić, Jasmina and Pokimica, Biljana and Petrović-Oggiano, Gordana and Tomić, Mirko and Ignjatović, Đurđica and Tovilović-Kovačević, Gordana and Glibetić, Marija",
year = "2016",
abstract = "Gender related differences in fatty acid composition of different lipid classes are well established. Changes in the proportions of specific long-chain PUFA in membrane phospholipids can alter cell and tissue function.
The aim of our study was to examine the effects of different diets on phospholipids fatty acids composition in rat's liver of both sexes and to compare them.
Adult Wistar rats of both sexes (n=8, 300g+5) were used in this study. Animals were fed with different type of diets (standard, fish-based and milk- based). The phospholipids fatty acid composition of liver was determined by Gas Chromatography using Shimadzu GC.
Diet changes the ratio of SFA, MUFA and PUFA but the effects were sex specific. Milk based diet lowered the amount of SFA (p<0.05) and elevated the ratio of MUFA (ANOVA diet effect, p<0.001) in males (ANOVA sex effect p<0.001, and interaction S x D, p<0.05), and PUFA, in females (ANOVA sex effect p<0.05, and diet effect p<0.05) comparing to standard diet. Milk based diet decreased n-3 (p<0.001), and increased n-6 (p<0.001) and n-6/n-3 (p<0.001) ratio in males comparing to the other type of diets. On the other hand, in females, fish based diet increased n-3 (p<0.001), decreased n-6 (p<0.001) and n-6/n-3 ratio (p<0.001) comparing to standard and milk based diets (ANOVA diet effect, p< 0.001, S x D effect, p<0.001, Tukey's post hoc).
Our results showed that each type of diet changes the composition of lipids and their ratio in the liver of rats. Fish based diet improving EPA and DHA fatty acid profiles and overall PUFA and has beneficial health effect.",
publisher = "Belgrade: Serbian Nutrition Society",
journal = "Book of Abstracts: 13th Congress of Nutrition Food and Nutrition: A Roadmap to Better Health; 2016 Oct 26-28; Belgrade, Serbia",
title = "Effects of different types of diet on liver fatty acids profiles in Wistar rats",
pages = "277",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6770"
}