TY  - JOUR
AU  - Pejin, Boris
AU  - Iodice, Carmine
AU  - Tommonaro, Giuseppina
AU  - Stanimirovic, Bojana
AU  - Ćirić, Ana
AU  - Glamočlija, Jasmina
AU  - Nikolić, Miloš
AU  - De Rosa, Salvatore
AU  - Soković, Marina
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2276
AB  - This work extends in vitro screening of antimicrobial activity of the
   sesquiterpene hydroquinone avarol, a main secondary metabolite of the
   Mediterranean sponge species Dysidea avara. The antimicrobial activity
   was in part evaluated by microdilution method against selected bacterial
   and fungal strains. Additionally, the screening included evaluation of
   anti-quorum sensing (anti-QS) effects. At a different extent avarol was
   proven to be active against all the microorganisms tested (MIC
   0.002-0.008 mg/mL and MBC 0.004-0.016 mg/mL; MIC 0.004-0.015 mg/mL and
   MFC 0.008-0.030 mg/mL; respectively). This marine natural product also
   showed moderate anti-QS effects, reducing Pseudomonas aeruginosa PAO1
   biofilm formation (75\%), its twitching and protrusions motilities as
   well as pyocianin production (39\%). According to the best of our
   knowledge, this is the first report both on avarol anti Gram-negative
   bacterial activity and anti-QS effects.
T2  - Current Pharmaceutical Biotechnology
T1  - Further in vitro Evaluation of Antimicrobial Activity of the Marine
 Sesquiterpene Hydroquinone Avarol
IS  - 6
VL  - 15
SP  - 583
EP  - 588
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_2276
ER  - 

@article{
author = "Pejin, Boris and Iodice, Carmine and Tommonaro, Giuseppina and Stanimirovic, Bojana and Ćirić, Ana and Glamočlija, Jasmina and Nikolić, Miloš and De Rosa, Salvatore and Soković, Marina",
year = "2014",
abstract = "This work extends in vitro screening of antimicrobial activity of the
   sesquiterpene hydroquinone avarol, a main secondary metabolite of the
   Mediterranean sponge species Dysidea avara. The antimicrobial activity
   was in part evaluated by microdilution method against selected bacterial
   and fungal strains. Additionally, the screening included evaluation of
   anti-quorum sensing (anti-QS) effects. At a different extent avarol was
   proven to be active against all the microorganisms tested (MIC
   0.002-0.008 mg/mL and MBC 0.004-0.016 mg/mL; MIC 0.004-0.015 mg/mL and
   MFC 0.008-0.030 mg/mL; respectively). This marine natural product also
   showed moderate anti-QS effects, reducing Pseudomonas aeruginosa PAO1
   biofilm formation (75\%), its twitching and protrusions motilities as
   well as pyocianin production (39\%). According to the best of our
   knowledge, this is the first report both on avarol anti Gram-negative
   bacterial activity and anti-QS effects.",
journal = "Current Pharmaceutical Biotechnology",
title = "Further in vitro Evaluation of Antimicrobial Activity of the Marine
 Sesquiterpene Hydroquinone Avarol",
number = "6",
volume = "15",
pages = "583-588",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_2276"
}

Pejin, B., Iodice, C., Tommonaro, G., Stanimirovic, B., Ćirić, A., Glamočlija, J., Nikolić, M., De Rosa, S.,& Soković, M.. (2014). Further in vitro Evaluation of Antimicrobial Activity of the Marine
 Sesquiterpene Hydroquinone Avarol. in Current Pharmaceutical Biotechnology, 15(6), 583-588.
https://hdl.handle.net/21.15107/rcub_ibiss_2276

Pejin B, Iodice C, Tommonaro G, Stanimirovic B, Ćirić A, Glamočlija J, Nikolić M, De Rosa S, Soković M. Further in vitro Evaluation of Antimicrobial Activity of the Marine
 Sesquiterpene Hydroquinone Avarol. in Current Pharmaceutical Biotechnology. 2014;15(6):583-588.
https://hdl.handle.net/21.15107/rcub_ibiss_2276 .

Pejin, Boris, Iodice, Carmine, Tommonaro, Giuseppina, Stanimirovic, Bojana, Ćirić, Ana, Glamočlija, Jasmina, Nikolić, Miloš, De Rosa, Salvatore, Soković, Marina, "Further in vitro Evaluation of Antimicrobial Activity of the Marine
 Sesquiterpene Hydroquinone Avarol" in Current Pharmaceutical Biotechnology, 15, no. 6 (2014):583-588,
https://hdl.handle.net/21.15107/rcub_ibiss_2276 .