TY  - JOUR
AU  - Nikolić, Biljana M.
AU  - Ballian, Dalibor A.
AU  - Đorđević, Iris Ž.
AU  - Rajčević, Nemanja F.
AU  - Todosijević, Marina M.
AU  - Stanković Jeremić, Jovana M.
AU  - Mitić, Zorica S.
AU  - Bojović, Srđan
AU  - Tešević, Vele V.
PY  - 2023
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0305197822001636
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5343
AB  - Population variability of n-alkanes in the cuticular waxes of Serbian spruce needles from Bosnia and Herzegovina was investigated for the first time. n-Alkanes exhibited composition variability ranging from C18 to C35. The divergence of populations from Bosnia and Herzegovina and previously investigated Serbian populations was statistically confirmed by PCA, DA, and CA (Cluster analysis), which could support the fact that there are two possible spruce chemotypes: one relating to the Bosnian-Herzegovinian and the other to the Serbian populations. Climate parameters (precipitation, temperature, wind, and solar radiation) approved this conclusion.
PB  - Elsevier Ltd.
T2  - Biochemical Systematics and Ecology
T1  - n-Alkanes variability in natural populations of Picea omorika (Pančić) Purk. From Bosnia and Herzegovina
VL  - 106
DO  - 10.1016/j.bse.2022.104544
SP  - 104544
ER  - 

@article{
author = "Nikolić, Biljana M. and Ballian, Dalibor A. and Đorđević, Iris Ž. and Rajčević, Nemanja F. and Todosijević, Marina M. and Stanković Jeremić, Jovana M. and Mitić, Zorica S. and Bojović, Srđan and Tešević, Vele V.",
year = "2023",
abstract = "Population variability of n-alkanes in the cuticular waxes of Serbian spruce needles from Bosnia and Herzegovina was investigated for the first time. n-Alkanes exhibited composition variability ranging from C18 to C35. The divergence of populations from Bosnia and Herzegovina and previously investigated Serbian populations was statistically confirmed by PCA, DA, and CA (Cluster analysis), which could support the fact that there are two possible spruce chemotypes: one relating to the Bosnian-Herzegovinian and the other to the Serbian populations. Climate parameters (precipitation, temperature, wind, and solar radiation) approved this conclusion.",
publisher = "Elsevier Ltd.",
journal = "Biochemical Systematics and Ecology",
title = "n-Alkanes variability in natural populations of Picea omorika (Pančić) Purk. From Bosnia and Herzegovina",
volume = "106",
doi = "10.1016/j.bse.2022.104544",
pages = "104544"
}

Nikolić, B. M., Ballian, D. A., Đorđević, I. Ž., Rajčević, N. F., Todosijević, M. M., Stanković Jeremić, J. M., Mitić, Z. S., Bojović, S.,& Tešević, V. V.. (2023). n-Alkanes variability in natural populations of Picea omorika (Pančić) Purk. From Bosnia and Herzegovina. in Biochemical Systematics and Ecology
Elsevier Ltd.., 106, 104544.
https://doi.org/10.1016/j.bse.2022.104544

Nikolić BM, Ballian DA, Đorđević IŽ, Rajčević NF, Todosijević MM, Stanković Jeremić JM, Mitić ZS, Bojović S, Tešević VV. n-Alkanes variability in natural populations of Picea omorika (Pančić) Purk. From Bosnia and Herzegovina. in Biochemical Systematics and Ecology. 2023;106:104544.
doi:10.1016/j.bse.2022.104544 .

Nikolić, Biljana M., Ballian, Dalibor A., Đorđević, Iris Ž., Rajčević, Nemanja F., Todosijević, Marina M., Stanković Jeremić, Jovana M., Mitić, Zorica S., Bojović, Srđan, Tešević, Vele V., "n-Alkanes variability in natural populations of Picea omorika (Pančić) Purk. From Bosnia and Herzegovina" in Biochemical Systematics and Ecology, 106 (2023):104544,
https://doi.org/10.1016/j.bse.2022.104544 . .

TY  - JOUR
AU  - Krstić, Gordana
AU  - Jadranin, Milka
AU  - Todorović, Nina M.
AU  - Pešić, Milica
AU  - Stanković, Tijana
AU  - Aljančić, Ivana S.
AU  - Tešević, Vele V.
PY  - 2018
UR  - https://www.sciencedirect.com/science/article/pii/S0031942218300232?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3003
AB  - Seven previously undescribed jatrophane diterpenoids, nicaeenin A-G, with eight known jatrophane diterpenoids, namely euphodendrophanes A-C, F, N, O, Q, S, were isolated from latex of Euphorbia nicaeensis collected in Serbia. The chemical structures of the compounds were determined by spectroscopic analysis including 1D and 2D NMR and HRESIMS experiments. All but one of the previously undescribed jatrophanes, showed significant potential to inhibit P-glycoprotein (P-gp) activity in two MDR cancer cells (NCI-H460/R and DLD1-TxR). The most powerful were nicaeenin F and nicaeenin G. Moreover nicaeenin G significantly stronger sensitized NCI-H460/R cells to DOX than Dex-VER.
PB  - Pergamon
T2  - Phytochemistry
T1  - Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis.
VL  - 148
DO  - 10.1016/j.phytochem.2018.01.016
SP  - 104
EP  - 112
ER  - 

@article{
author = "Krstić, Gordana and Jadranin, Milka and Todorović, Nina M. and Pešić, Milica and Stanković, Tijana and Aljančić, Ivana S. and Tešević, Vele V.",
year = "2018",
abstract = "Seven previously undescribed jatrophane diterpenoids, nicaeenin A-G, with eight known jatrophane diterpenoids, namely euphodendrophanes A-C, F, N, O, Q, S, were isolated from latex of Euphorbia nicaeensis collected in Serbia. The chemical structures of the compounds were determined by spectroscopic analysis including 1D and 2D NMR and HRESIMS experiments. All but one of the previously undescribed jatrophanes, showed significant potential to inhibit P-glycoprotein (P-gp) activity in two MDR cancer cells (NCI-H460/R and DLD1-TxR). The most powerful were nicaeenin F and nicaeenin G. Moreover nicaeenin G significantly stronger sensitized NCI-H460/R cells to DOX than Dex-VER.",
publisher = "Pergamon",
journal = "Phytochemistry",
title = "Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis.",
volume = "148",
doi = "10.1016/j.phytochem.2018.01.016",
pages = "104-112"
}

Krstić, G., Jadranin, M., Todorović, N. M., Pešić, M., Stanković, T., Aljančić, I. S.,& Tešević, V. V.. (2018). Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis.. in Phytochemistry
Pergamon., 148, 104-112.
https://doi.org/10.1016/j.phytochem.2018.01.016

Krstić G, Jadranin M, Todorović NM, Pešić M, Stanković T, Aljančić IS, Tešević VV. Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis.. in Phytochemistry. 2018;148:104-112.
doi:10.1016/j.phytochem.2018.01.016 .

Krstić, Gordana, Jadranin, Milka, Todorović, Nina M., Pešić, Milica, Stanković, Tijana, Aljančić, Ivana S., Tešević, Vele V., "Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis." in Phytochemistry, 148 (2018):104-112,
https://doi.org/10.1016/j.phytochem.2018.01.016 . .

TY  - JOUR
AU  - Nikolić, Biljana M.
AU  - Mitić, Zorica S.
AU  - Tešević, Vele V.
AU  - Đorđević, Iris Ž.
AU  - Todosijević, Marina M.
AU  - Bojović, Srđan
AU  - Marin, Petar D.
PY  - 2018
UR  - http://doi.wiley.com/10.1002/cbdv.201800161
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3133
AB  - The n‐alkane composition in the leaf cuticular waxes of natural populations of Bosnian pine (Pinus heldreichii), Austrian pine (P. nigra), and Macedonian pine (P. peuce) was compared for the first time. The range of n‐alkanes was wider in P. nigra (C16 – C33) than in P. heldreichii and P. peuce (C18 – C33). Species also diverged in abundance and range of dominant n‐alkanes (P. heldreichii: C23, C27, and C25; P. nigra: C25, C27, C29, and C23; P. peuce: C29, C25, C27, and C23). Multivariate statistical analyses (PCA, DA, and CA) generally pointed out separation of populations of P. nigra from populations of P. heldreichii and P. peuce (which were, to a greater or lesser extent, separated too). However, position of these species on the basis of n‐alkane composition was in accordance neither with infrageneric classification nor with recent molecular and terpene investigations.
PB  - Wiley-Blackwell
T2  - Chemistry & Biodiversity
T1  - Chemotaxonomic Considerations of the n -Alkane Composition in Pinus heldreichii , P. nigra , and P. peuce
DO  - 10.1002/cbdv.201800161
ER  - 

@article{
author = "Nikolić, Biljana M. and Mitić, Zorica S. and Tešević, Vele V. and Đorđević, Iris Ž. and Todosijević, Marina M. and Bojović, Srđan and Marin, Petar D.",
year = "2018",
abstract = "The n‐alkane composition in the leaf cuticular waxes of natural populations of Bosnian pine (Pinus heldreichii), Austrian pine (P. nigra), and Macedonian pine (P. peuce) was compared for the first time. The range of n‐alkanes was wider in P. nigra (C16 – C33) than in P. heldreichii and P. peuce (C18 – C33). Species also diverged in abundance and range of dominant n‐alkanes (P. heldreichii: C23, C27, and C25; P. nigra: C25, C27, C29, and C23; P. peuce: C29, C25, C27, and C23). Multivariate statistical analyses (PCA, DA, and CA) generally pointed out separation of populations of P. nigra from populations of P. heldreichii and P. peuce (which were, to a greater or lesser extent, separated too). However, position of these species on the basis of n‐alkane composition was in accordance neither with infrageneric classification nor with recent molecular and terpene investigations.",
publisher = "Wiley-Blackwell",
journal = "Chemistry & Biodiversity",
title = "Chemotaxonomic Considerations of the n -Alkane Composition in Pinus heldreichii , P. nigra , and P. peuce",
doi = "10.1002/cbdv.201800161"
}

Nikolić, B. M., Mitić, Z. S., Tešević, V. V., Đorđević, I. Ž., Todosijević, M. M., Bojović, S.,& Marin, P. D.. (2018). Chemotaxonomic Considerations of the n -Alkane Composition in Pinus heldreichii , P. nigra , and P. peuce. in Chemistry & Biodiversity
Wiley-Blackwell..
https://doi.org/10.1002/cbdv.201800161

Nikolić BM, Mitić ZS, Tešević VV, Đorđević IŽ, Todosijević MM, Bojović S, Marin PD. Chemotaxonomic Considerations of the n -Alkane Composition in Pinus heldreichii , P. nigra , and P. peuce. in Chemistry & Biodiversity. 2018;.
doi:10.1002/cbdv.201800161 .

Nikolić, Biljana M., Mitić, Zorica S., Tešević, Vele V., Đorđević, Iris Ž., Todosijević, Marina M., Bojović, Srđan, Marin, Petar D., "Chemotaxonomic Considerations of the n -Alkane Composition in Pinus heldreichii , P. nigra , and P. peuce" in Chemistry & Biodiversity (2018),
https://doi.org/10.1002/cbdv.201800161 . .

TY  - JOUR
AU  - Bojović, Srđan
AU  - Mitić, Zorica S.
AU  - Nikolić, Biljana M.
AU  - Ristić, Mihailo S.
AU  - Tešević, Vele V.
AU  - Marin, Petar D.
PY  - 2017
UR  - http://doi.wiley.com/10.1002/cbdv.201700093
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2794
AB  - Comparative analysis of terpene diversity and differentiation of relict pines Pinus heldreichii, P. nigra, and P. peuce from the central Balkans was performed at the population level. Multivariate statistical analyses showed that the composition of needle terpenes reflects clear divergence among the pine species from different subgenera: P. peuce (subgenus Strobus) vs. P. nigra and P. heldreichii (subgenus Pinus). In addition, despite the described morphological similarities and the fact that P. nigra and P. heldreichii may spontaneously hybridize, our results indicated differentiation of their populations naturally growing in the same area. In accordance with recently proposed concept of 'flavonic evolution' in the genus Pinus, we assumed that the terpene profile of soft pine P. peuce, defined by high amounts of six monoterpenes, is more basal than those of hard pines P. nigra and P. heldreichii, which were characterized by high content levels of mainly sesquiterpenes. In order to establish precise positions of P. heldreichii, P. nigra and P. peuce within the taxonomic and phylogenetic tree, as well as develop suitable conservation strategies and future breeding efforts, it is necessary to perform additional morphological, biochemical, and genetic studies.
T2  - Chemistry and Biodiversity
T1  - Terpenes as Useful Markers in Differentiation of Natural Populations of Relict Pines Pinus heldreichii , P . nigra , and P . peuce
DO  - 10.1002/cbdv.201700093
ER  - 

@article{
author = "Bojović, Srđan and Mitić, Zorica S. and Nikolić, Biljana M. and Ristić, Mihailo S. and Tešević, Vele V. and Marin, Petar D.",
year = "2017",
abstract = "Comparative analysis of terpene diversity and differentiation of relict pines Pinus heldreichii, P. nigra, and P. peuce from the central Balkans was performed at the population level. Multivariate statistical analyses showed that the composition of needle terpenes reflects clear divergence among the pine species from different subgenera: P. peuce (subgenus Strobus) vs. P. nigra and P. heldreichii (subgenus Pinus). In addition, despite the described morphological similarities and the fact that P. nigra and P. heldreichii may spontaneously hybridize, our results indicated differentiation of their populations naturally growing in the same area. In accordance with recently proposed concept of 'flavonic evolution' in the genus Pinus, we assumed that the terpene profile of soft pine P. peuce, defined by high amounts of six monoterpenes, is more basal than those of hard pines P. nigra and P. heldreichii, which were characterized by high content levels of mainly sesquiterpenes. In order to establish precise positions of P. heldreichii, P. nigra and P. peuce within the taxonomic and phylogenetic tree, as well as develop suitable conservation strategies and future breeding efforts, it is necessary to perform additional morphological, biochemical, and genetic studies.",
journal = "Chemistry and Biodiversity",
title = "Terpenes as Useful Markers in Differentiation of Natural Populations of Relict Pines Pinus heldreichii , P . nigra , and P . peuce",
doi = "10.1002/cbdv.201700093"
}

Bojović, S., Mitić, Z. S., Nikolić, B. M., Ristić, M. S., Tešević, V. V.,& Marin, P. D.. (2017). Terpenes as Useful Markers in Differentiation of Natural Populations of Relict Pines Pinus heldreichii , P . nigra , and P . peuce. in Chemistry and Biodiversity.
https://doi.org/10.1002/cbdv.201700093

Bojović S, Mitić ZS, Nikolić BM, Ristić MS, Tešević VV, Marin PD. Terpenes as Useful Markers in Differentiation of Natural Populations of Relict Pines Pinus heldreichii , P . nigra , and P . peuce. in Chemistry and Biodiversity. 2017;.
doi:10.1002/cbdv.201700093 .

Bojović, Srđan, Mitić, Zorica S., Nikolić, Biljana M., Ristić, Mihailo S., Tešević, Vele V., Marin, Petar D., "Terpenes as Useful Markers in Differentiation of Natural Populations of Relict Pines Pinus heldreichii , P . nigra , and P . peuce" in Chemistry and Biodiversity (2017),
https://doi.org/10.1002/cbdv.201700093 . .

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Trifunović, Snežana S.
AU  - Ćirić, Ana
AU  - Šakić, Željana M.
AU  - Ristić, Mihailo S.
AU  - Todorović, Nina M.
AU  - Matevski, Vlado S.
AU  - Marin, Petar D.
AU  - Tešević, Vele V.
AU  - Džamić, Ana M.
PY  - 2017
UR  - http://pubs.acs.org/doi/10.1021/acs.jafc.7b04202
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2952
AB  - The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and β-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonas aeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).
T2  - Journal of Agricultural and Food Chemistry
T1  - Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots
IS  - 50
VL  - 65
DO  - 10.1021/acs.jafc.7b04202
SP  - 10933
EP  - 10949
ER  - 

@article{
author = "Mileski, Ksenija S. and Trifunović, Snežana S. and Ćirić, Ana and Šakić, Željana M. and Ristić, Mihailo S. and Todorović, Nina M. and Matevski, Vlado S. and Marin, Petar D. and Tešević, Vele V. and Džamić, Ana M.",
year = "2017",
abstract = "The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and β-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonas aeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).",
journal = "Journal of Agricultural and Food Chemistry",
title = "Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots",
number = "50",
volume = "65",
doi = "10.1021/acs.jafc.7b04202",
pages = "10933-10949"
}

Mileski, K. S., Trifunović, S. S., Ćirić, A., Šakić, Ž. M., Ristić, M. S., Todorović, N. M., Matevski, V. S., Marin, P. D., Tešević, V. V.,& Džamić, A. M.. (2017). Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots. in Journal of Agricultural and Food Chemistry, 65(50), 10933-10949.
https://doi.org/10.1021/acs.jafc.7b04202

Mileski KS, Trifunović SS, Ćirić A, Šakić ŽM, Ristić MS, Todorović NM, Matevski VS, Marin PD, Tešević VV, Džamić AM. Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots. in Journal of Agricultural and Food Chemistry. 2017;65(50):10933-10949.
doi:10.1021/acs.jafc.7b04202 .

Mileski, Ksenija S., Trifunović, Snežana S., Ćirić, Ana, Šakić, Željana M., Ristić, Mihailo S., Todorović, Nina M., Matevski, Vlado S., Marin, Petar D., Tešević, Vele V., Džamić, Ana M., "Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots" in Journal of Agricultural and Food Chemistry, 65, no. 50 (2017):10933-10949,
https://doi.org/10.1021/acs.jafc.7b04202 . .

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Ćirić, Ana
AU  - Trifunović, Snežana S.
AU  - Ristić, Mihailo S.
AU  - Soković, Marina
AU  - Matevski, Vlado S.
AU  - Tešević, Vele V.
AU  - Jadranin, Milka B.
AU  - Marin, Petar D.
AU  - Džamić, Ana M.
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6745
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerialparts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts ofaerial parts and roots was determined. The main components of the essential oil were n-octanol, octylhexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanolextracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerialparts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, theessential oil and methanol extract of the roots showed the greatest effectiveness. The colonies ofPseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin,showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in thisstudy showed the considerable biological potential of H. orphanidis considering free radicals and variouspathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Society of Chemistry
T2  - Food and Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
DO  - 10.1039/c6fo01018k
SP  - 4061
ER  - 

@article{
author = "Mileski, Ksenija S. and Ćirić, Ana and Trifunović, Snežana S. and Ristić, Mihailo S. and Soković, Marina and Matevski, Vlado S. and Tešević, Vele V. and Jadranin, Milka B. and Marin, Petar D. and Džamić, Ana M.",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerialparts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts ofaerial parts and roots was determined. The main components of the essential oil were n-octanol, octylhexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanolextracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerialparts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, theessential oil and methanol extract of the roots showed the greatest effectiveness. The colonies ofPseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin,showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in thisstudy showed the considerable biological potential of H. orphanidis considering free radicals and variouspathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Society of Chemistry",
journal = "Food and Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
doi = "10.1039/c6fo01018k",
pages = "4061"
}

Mileski, K. S., Ćirić, A., Trifunović, S. S., Ristić, M. S., Soković, M., Matevski, V. S., Tešević, V. V., Jadranin, M. B., Marin, P. D.,& Džamić, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function
Royal Society of Chemistry., 7, 4061.
https://doi.org/10.1039/c6fo01018k

Mileski KS, Ćirić A, Trifunović SS, Ristić MS, Soković M, Matevski VS, Tešević VV, Jadranin MB, Marin PD, Džamić AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function. 2016;7:4061.
doi:10.1039/c6fo01018k .

Mileski, Ksenija S., Ćirić, Ana, Trifunović, Snežana S., Ristić, Mihailo S., Soković, Marina, Matevski, Vlado S., Tešević, Vele V., Jadranin, Milka B., Marin, Petar D., Džamić, Ana M., "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food and Function, 7 (2016):4061,
https://doi.org/10.1039/c6fo01018k . .

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Ćirić, Ana
AU  - Trifunović, Snežana S.
AU  - Ristić, Mihailo S.
AU  - Soković, Marina
AU  - Matevski, Vlado S.
AU  - Tešević, Vele V.
AU  - Jadranin, Milka B.
AU  - Marin, Petar D.
AU  - Džamić, Ana M.
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6744
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial
parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of
aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl
hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol
extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial
parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the
essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of
Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin,
showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this
study showed the considerable biological potential of H. orphanidis considering free radicals and various
pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Society of Chemistry
T2  - Food and Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
DO  - 10.1039/c6fo01018k
SP  - 4061
ER  - 

@article{
author = "Mileski, Ksenija S. and Ćirić, Ana and Trifunović, Snežana S. and Ristić, Mihailo S. and Soković, Marina and Matevski, Vlado S. and Tešević, Vele V. and Jadranin, Milka B. and Marin, Petar D. and Džamić, Ana M.",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial
parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of
aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl
hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol
extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial
parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the
essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of
Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin,
showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this
study showed the considerable biological potential of H. orphanidis considering free radicals and various
pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Society of Chemistry",
journal = "Food and Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
doi = "10.1039/c6fo01018k",
pages = "4061"
}

Mileski, K. S., Ćirić, A., Trifunović, S. S., Ristić, M. S., Soković, M., Matevski, V. S., Tešević, V. V., Jadranin, M. B., Marin, P. D.,& Džamić, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function
Royal Society of Chemistry., 7, 4061.
https://doi.org/10.1039/c6fo01018k

Mileski KS, Ćirić A, Trifunović SS, Ristić MS, Soković M, Matevski VS, Tešević VV, Jadranin MB, Marin PD, Džamić AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function. 2016;7:4061.
doi:10.1039/c6fo01018k .

Mileski, Ksenija S., Ćirić, Ana, Trifunović, Snežana S., Ristić, Mihailo S., Soković, Marina, Matevski, Vlado S., Tešević, Vele V., Jadranin, Milka B., Marin, Petar D., Džamić, Ana M., "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food and Function, 7 (2016):4061,
https://doi.org/10.1039/c6fo01018k . .