TY  - JOUR
AU  - Mitić, Bojan
AU  - Borković-Mitić, Slavica
AU  - Vranković, Jelena
AU  - Stojanović, Dalibor
AU  - Pavlović, Slađan
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5658
AB  - The activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR),
and glutathione S-transferase (GST), as well as the concentrations of sulfhydryl (SH) groups and glutathione (GSH) were
analyzed in five age classes of the Mediterranean centipede Scolopendra cingulata as follows: embryo, adolescens, maturus
junior, maturus, and maturus senior. The data obtained showed the presence of SOD, CAT, GSH-Px, GR, GST, and SH
groups in embryos. The transition from embryo to adolescens was accompanied by an increase in the activities of all studied
enzymes, in response to the increased production of ROS due to the increased metabolic activity of the centipede associated with growth and development. Our results show that trends in antioxidant enzyme (AOE) activities were not uniform
among adult age classes, suggesting that maturus junior, maturus, and maturus senior differentially respond and/or have
different susceptibility to ROS. On the other hand, GSH concentration in embryos was undetectable, highest in adolescens
and decreased in the latter part of life. Pearson correlation analysis in embryos showed that the activities of the AOEs were
strongly and positively correlated with each other but negatively correlated with GSH and SH groups. At later age classes,
SOD, CAT, GSH-Px, GR, GSH, and SH groups were no longer significantly correlated with GST. In the discriminant analysis,
the variables that separated the age classes were GR, GST, SH groups, and body length. Body length was directly related to
the age of individuals, clearly indicating that development/aging affects the regulation of antioxidant defense in this species.
PB  - Heidelberg: Springer
T2  - Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology
T1  - Age‑related changes in antioxidant defenses of the Mediterranean centipede Scolopendra cingulata (Chilopoda)
DO  - 10.1007/s00360-023-01481-w
ER  - 

@article{
author = "Mitić, Bojan and Borković-Mitić, Slavica and Vranković, Jelena and Stojanović, Dalibor and Pavlović, Slađan",
year = "2023",
abstract = "The activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR),
and glutathione S-transferase (GST), as well as the concentrations of sulfhydryl (SH) groups and glutathione (GSH) were
analyzed in five age classes of the Mediterranean centipede Scolopendra cingulata as follows: embryo, adolescens, maturus
junior, maturus, and maturus senior. The data obtained showed the presence of SOD, CAT, GSH-Px, GR, GST, and SH
groups in embryos. The transition from embryo to adolescens was accompanied by an increase in the activities of all studied
enzymes, in response to the increased production of ROS due to the increased metabolic activity of the centipede associated with growth and development. Our results show that trends in antioxidant enzyme (AOE) activities were not uniform
among adult age classes, suggesting that maturus junior, maturus, and maturus senior differentially respond and/or have
different susceptibility to ROS. On the other hand, GSH concentration in embryos was undetectable, highest in adolescens
and decreased in the latter part of life. Pearson correlation analysis in embryos showed that the activities of the AOEs were
strongly and positively correlated with each other but negatively correlated with GSH and SH groups. At later age classes,
SOD, CAT, GSH-Px, GR, GSH, and SH groups were no longer significantly correlated with GST. In the discriminant analysis,
the variables that separated the age classes were GR, GST, SH groups, and body length. Body length was directly related to
the age of individuals, clearly indicating that development/aging affects the regulation of antioxidant defense in this species.",
publisher = "Heidelberg: Springer",
journal = "Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology",
title = "Age‑related changes in antioxidant defenses of the Mediterranean centipede Scolopendra cingulata (Chilopoda)",
doi = "10.1007/s00360-023-01481-w"
}

Mitić, B., Borković-Mitić, S., Vranković, J., Stojanović, D.,& Pavlović, S.. (2023). Age‑related changes in antioxidant defenses of the Mediterranean centipede Scolopendra cingulata (Chilopoda). in Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology
Heidelberg: Springer..
https://doi.org/10.1007/s00360-023-01481-w

Mitić B, Borković-Mitić S, Vranković J, Stojanović D, Pavlović S. Age‑related changes in antioxidant defenses of the Mediterranean centipede Scolopendra cingulata (Chilopoda). in Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 2023;.
doi:10.1007/s00360-023-01481-w .

Mitić, Bojan, Borković-Mitić, Slavica, Vranković, Jelena, Stojanović, Dalibor, Pavlović, Slađan, "Age‑related changes in antioxidant defenses of the Mediterranean centipede Scolopendra cingulata (Chilopoda)" in Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology (2023),
https://doi.org/10.1007/s00360-023-01481-w . .