TY  - JOUR
AU  - Mitrović, Marko
AU  - Tatalović, Nikola
AU  - Nikolić-Kokić, Aleksandra
AU  - Ciraj-Bjelac, Olivera
AU  - Krstić, Nikola
AU  - Oreščanin Dušić, Zorana
AU  - Krstić, Dragana
AU  - Jovanović, Zoran
AU  - Blagojević, Duško
AU  - Lazarević-Macanović, Mirjana
PY  - 2018
UR  - http://www.doiserbia.nb.rs/Article.aspx?ID=0354-46641800029M
UR  - http://www.serbiosoc.org.rs/arch/index.php/abs/article/view/2841
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3226
AB  - In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.
T2  - Archives of Biological Sciences
T1  - Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles
IS  - 4
VL  - 70
DO  - 10.2298/ABS180413029M
SP  - 675
EP  - 680
ER  - 

@article{
author = "Mitrović, Marko and Tatalović, Nikola and Nikolić-Kokić, Aleksandra and Ciraj-Bjelac, Olivera and Krstić, Nikola and Oreščanin Dušić, Zorana and Krstić, Dragana and Jovanović, Zoran and Blagojević, Duško and Lazarević-Macanović, Mirjana",
year = "2018",
abstract = "In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.",
journal = "Archives of Biological Sciences",
title = "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles",
number = "4",
volume = "70",
doi = "10.2298/ABS180413029M",
pages = "675-680"
}

Mitrović, M., Tatalović, N., Nikolić-Kokić, A., Ciraj-Bjelac, O., Krstić, N., Oreščanin Dušić, Z., Krstić, D., Jovanović, Z., Blagojević, D.,& Lazarević-Macanović, M.. (2018). Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences, 70(4), 675-680.
https://doi.org/10.2298/ABS180413029M

Mitrović M, Tatalović N, Nikolić-Kokić A, Ciraj-Bjelac O, Krstić N, Oreščanin Dušić Z, Krstić D, Jovanović Z, Blagojević D, Lazarević-Macanović M. Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences. 2018;70(4):675-680.
doi:10.2298/ABS180413029M .

Mitrović, Marko, Tatalović, Nikola, Nikolić-Kokić, Aleksandra, Ciraj-Bjelac, Olivera, Krstić, Nikola, Oreščanin Dušić, Zorana, Krstić, Dragana, Jovanović, Zoran, Blagojević, Duško, Lazarević-Macanović, Mirjana, "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles" in Archives of Biological Sciences, 70, no. 4 (2018):675-680,
https://doi.org/10.2298/ABS180413029M . .

TY  - JOUR
AU  - Mitrović, Marko B.
AU  - Ciraj-Bjelac, Olivera F.
AU  - Oreščanin Dušić, Zorana
AU  - Blagojević, Duško
AU  - Nikolić-Kokić, Aleksandra
AU  - Tatalović, Nikola
AU  - Krstić, Nikola E.
AU  - Lazarević-Macanović, Mirjana V.
PY  - 2017
UR  - http://ntrp.vinca.rs/2017_4/Mitrovic2017_4.html
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2967
AB  - The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.
T2  - Nuclear Technology and Radiation Protection
T1  - Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes
IS  - 4
VL  - 32
DO  - 10.2298/NTRP1704342M
SP  - 342
EP  - 349
ER  - 

@article{
author = "Mitrović, Marko B. and Ciraj-Bjelac, Olivera F. and Oreščanin Dušić, Zorana and Blagojević, Duško and Nikolić-Kokić, Aleksandra and Tatalović, Nikola and Krstić, Nikola E. and Lazarević-Macanović, Mirjana V.",
year = "2017",
abstract = "The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.",
journal = "Nuclear Technology and Radiation Protection",
title = "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes",
number = "4",
volume = "32",
doi = "10.2298/NTRP1704342M",
pages = "342-349"
}

Mitrović, M. B., Ciraj-Bjelac, O. F., Oreščanin Dušić, Z., Blagojević, D., Nikolić-Kokić, A., Tatalović, N., Krstić, N. E.,& Lazarević-Macanović, M. V.. (2017). Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection, 32(4), 342-349.
https://doi.org/10.2298/NTRP1704342M

Mitrović MB, Ciraj-Bjelac OF, Oreščanin Dušić Z, Blagojević D, Nikolić-Kokić A, Tatalović N, Krstić NE, Lazarević-Macanović MV. Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection. 2017;32(4):342-349.
doi:10.2298/NTRP1704342M .

Mitrović, Marko B., Ciraj-Bjelac, Olivera F., Oreščanin Dušić, Zorana, Blagojević, Duško, Nikolić-Kokić, Aleksandra, Tatalović, Nikola, Krstić, Nikola E., Lazarević-Macanović, Mirjana V., "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes" in Nuclear Technology and Radiation Protection, 32, no. 4 (2017):342-349,
https://doi.org/10.2298/NTRP1704342M . .

TY  - JOUR
AU  - Lazić, Marko M
AU  - Carretero, Miguel A
AU  - Mihajilov-Krstev, Tatjana M
AU  - Lazarević-Macanović, Mirjana
AU  - Krstić, Nikola E
AU  - Crnobrnja-Isailović, Jelka M.
PY  - 2012
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1077
AB  - Skin lesions frequently present in adult lizards may be due to a variety of causes, both physical and infectious, including excessively high humidity and environmental temperature, malnutrition, concurrent disease etc. On the other hand, skin lesions in lizards could be simple evidence of various behavioural patterns and biotic interactions. However, studies on frequencies of dermal lesions and their anatomical and environmental correlates in lacertid lizards are rare. Here, we use Podarcis muralis to analyse the relations between occurrence of ectodermal lesions and three possible indicators of environmental stress (body condition index - BCI, infestation by ticks and tail condition) by evaluating differences among local populations at uni- and multivariate level. Our results showed that BCI, together with body size and sexual size dimorphism, varied between populations but had no direct influence on the presence of lesions. Males had higher frequencies of lesions and ticks but lower frequencies of broken tails than females. All three parameters varied between sites likely due to differences in predation/parasite exposures and agonistic interactions with conspecifics between sexes and populations. Results of multivariate analyses suggested that the occurrence of lesions is decoupled from the other morphological stress indicators. Detected associations indicated that relations between presence of lesions and other analysed variables are rather complex. Directions for further research on ectodermal lesions in lacertid lizards are provided.
T2  - Amphibia-Reptilia
T1  - Incidence patterns of ectodermic lesions in wild populations of Common Wall Lizard (Podarcis muralis)
IS  - 3-4
VL  - 33
SP  - 115
EP  - 336
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1077
ER  - 

@article{
author = "Lazić, Marko M and Carretero, Miguel A and Mihajilov-Krstev, Tatjana M and Lazarević-Macanović, Mirjana and Krstić, Nikola E and Crnobrnja-Isailović, Jelka M.",
year = "2012",
abstract = "Skin lesions frequently present in adult lizards may be due to a variety of causes, both physical and infectious, including excessively high humidity and environmental temperature, malnutrition, concurrent disease etc. On the other hand, skin lesions in lizards could be simple evidence of various behavioural patterns and biotic interactions. However, studies on frequencies of dermal lesions and their anatomical and environmental correlates in lacertid lizards are rare. Here, we use Podarcis muralis to analyse the relations between occurrence of ectodermal lesions and three possible indicators of environmental stress (body condition index - BCI, infestation by ticks and tail condition) by evaluating differences among local populations at uni- and multivariate level. Our results showed that BCI, together with body size and sexual size dimorphism, varied between populations but had no direct influence on the presence of lesions. Males had higher frequencies of lesions and ticks but lower frequencies of broken tails than females. All three parameters varied between sites likely due to differences in predation/parasite exposures and agonistic interactions with conspecifics between sexes and populations. Results of multivariate analyses suggested that the occurrence of lesions is decoupled from the other morphological stress indicators. Detected associations indicated that relations between presence of lesions and other analysed variables are rather complex. Directions for further research on ectodermal lesions in lacertid lizards are provided.",
journal = "Amphibia-Reptilia",
title = "Incidence patterns of ectodermic lesions in wild populations of Common Wall Lizard (Podarcis muralis)",
number = "3-4",
volume = "33",
pages = "115-336",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1077"
}

Lazić, M. M., Carretero, M. A., Mihajilov-Krstev, T. M., Lazarević-Macanović, M., Krstić, N. E.,& Crnobrnja-Isailović, J. M.. (2012). Incidence patterns of ectodermic lesions in wild populations of Common Wall Lizard (Podarcis muralis). in Amphibia-Reptilia, 33(3-4), 115-336.
https://hdl.handle.net/21.15107/rcub_ibiss_1077

Lazić MM, Carretero MA, Mihajilov-Krstev TM, Lazarević-Macanović M, Krstić NE, Crnobrnja-Isailović JM. Incidence patterns of ectodermic lesions in wild populations of Common Wall Lizard (Podarcis muralis). in Amphibia-Reptilia. 2012;33(3-4):115-336.
https://hdl.handle.net/21.15107/rcub_ibiss_1077 .

Lazić, Marko M, Carretero, Miguel A, Mihajilov-Krstev, Tatjana M, Lazarević-Macanović, Mirjana, Krstić, Nikola E, Crnobrnja-Isailović, Jelka M., "Incidence patterns of ectodermic lesions in wild populations of Common Wall Lizard (Podarcis muralis)" in Amphibia-Reptilia, 33, no. 3-4 (2012):115-336,
https://hdl.handle.net/21.15107/rcub_ibiss_1077 .