TY  - JOUR
AU  - Živković, Jelena
AU  - Stojković, Dejan
AU  - Petrović, Jovana
AU  - Zdunić, Gordana
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2039
AB  - Health beneficial properties of Rosa canina species are mainly
   attributed to rose hips, while the leaves are usually discarded as
   waste. In the present study we investigated chemical constituents as
   well as antimicrobial and antibiofilm potential of R. canina methanolic
   leaf extract. Chemical analysis showed that dominant phenolic compounds
   are quercetin and isorhamnetin derivatives (isoquercetin and
   isorhamnetin-3-O-rutinoside). Among the tested bacteria, Pseudomonas
   aeruginosa and Salmonella typhimurium were the most susceptible to the
   activity of R. canina leaf extract with MIC and MBC values both 0.009 mg
   mL(-1). For most of the bacterial strains investigated the extract
   showed significantly higher activity compared to the used standard
   compounds streptomycin and ampicillin. Also the tested extract
   powerfully inhibited in vitro biofilm growth in Pseudomonas aeruginosa,
   Staphylococcus aureus, Leishmania monocytogenes and Escherichia coli at
   sub MIC-levels. With concentrations equal to 1/4 and 1/8 of MIC values
   biofilm growth of P. aeruginosa and E. coli was inhibited by 90\%. The
   obtained results are significant for a wider and efficient use of R.
   canina leaves.
T2  - Food & Function
T1  - Rosa canina L. - new possibilities for an old medicinal herb
IS  - 12
VL  - 6
DO  - 10.1039/c5fo00820d
SP  - 3687
EP  - 3692
ER  - 

@article{
author = "Živković, Jelena and Stojković, Dejan and Petrović, Jovana and Zdunić, Gordana and Glamočlija, Jasmina and Soković, Marina",
year = "2015",
abstract = "Health beneficial properties of Rosa canina species are mainly
   attributed to rose hips, while the leaves are usually discarded as
   waste. In the present study we investigated chemical constituents as
   well as antimicrobial and antibiofilm potential of R. canina methanolic
   leaf extract. Chemical analysis showed that dominant phenolic compounds
   are quercetin and isorhamnetin derivatives (isoquercetin and
   isorhamnetin-3-O-rutinoside). Among the tested bacteria, Pseudomonas
   aeruginosa and Salmonella typhimurium were the most susceptible to the
   activity of R. canina leaf extract with MIC and MBC values both 0.009 mg
   mL(-1). For most of the bacterial strains investigated the extract
   showed significantly higher activity compared to the used standard
   compounds streptomycin and ampicillin. Also the tested extract
   powerfully inhibited in vitro biofilm growth in Pseudomonas aeruginosa,
   Staphylococcus aureus, Leishmania monocytogenes and Escherichia coli at
   sub MIC-levels. With concentrations equal to 1/4 and 1/8 of MIC values
   biofilm growth of P. aeruginosa and E. coli was inhibited by 90\%. The
   obtained results are significant for a wider and efficient use of R.
   canina leaves.",
journal = "Food & Function",
title = "Rosa canina L. - new possibilities for an old medicinal herb",
number = "12",
volume = "6",
doi = "10.1039/c5fo00820d",
pages = "3687-3692"
}

Živković, J., Stojković, D., Petrović, J., Zdunić, G., Glamočlija, J.,& Soković, M.. (2015). Rosa canina L. - new possibilities for an old medicinal herb. in Food & Function, 6(12), 3687-3692.
https://doi.org/10.1039/c5fo00820d

Živković J, Stojković D, Petrović J, Zdunić G, Glamočlija J, Soković M. Rosa canina L. - new possibilities for an old medicinal herb. in Food & Function. 2015;6(12):3687-3692.
doi:10.1039/c5fo00820d .

Živković, Jelena, Stojković, Dejan, Petrović, Jovana, Zdunić, Gordana, Glamočlija, Jasmina, Soković, Marina, "Rosa canina L. - new possibilities for an old medicinal herb" in Food & Function, 6, no. 12 (2015):3687-3692,
https://doi.org/10.1039/c5fo00820d . .