Biočanin, Vladimir

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  • Biočanin, Vladimir (5)
Projects

Author's Bibliography

The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex

Tambur, Zoran; Aleksić, Ema; Čabrilo Lazić, Milana; Opačić, Dolores; Kalevski, Katarina; Puletić, Miljan; Avramov, Stevan; Biočanin, Vladimir

(Tramaniglio, Italy: The Journal of Infection in Developing Countries Non-Profit organization, 2023)

TY  - JOUR
AU  - Tambur, Zoran
AU  - Aleksić, Ema
AU  - Čabrilo Lazić, Milana
AU  - Opačić, Dolores
AU  - Kalevski, Katarina
AU  - Puletić, Miljan
AU  - Avramov, Stevan
AU  - Biočanin, Vladimir
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6653
AB  - This study aimed to investigate the possibility of applying the hyperlight fluid fusion essential complex in dental plaque control, and to evaluate the effectiveness of new and modern agents used for the prevention and early treatment of gingivitis. Methodology:  The  study  included  60  subjects  randomly  divided  into  two  groups.  The  control  group  was  assigned  to  0.12%  chlorhexidine  (CHX) mouth rinse, whereas the test group used a solution based on hyper-harmonized hydroxylated fullerene water complex (3HFWC), twice daily for 2 weeks. The plaque, gingivitis and bleeding scores were evaluated and recorded. Collected plaque samples were seeded on blood agar  and  incubated  aerobically  at  a  temperature  of  37  °C  for  24-48  hours.  In  order  to  isolate  anaerobic  bacteria,  samples  were  seeded  on  Schaedler Agar and incubated anaerobically at 37 °C for seven days. Serial dilutions in saline from 101 - 106 were made, and grown colonies were counted and identified using the matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) system. Results: The reduction in the number of bacteria was significant in both control and test groups. The reduction was greater in the control group compared to the experimental group, but without statistically significant difference.Conclusions: 3HFWC treatment causes significant reduction in the number of dental plaque microorganisms. Since 3HFWC solution exhibited a  bacteriostatic  effect  similar  to  chlorhexidine  it  could  be  an  adequate  addition  to  solution  of  a  growing  problem  in  prevention  and  early treatment of gingivitis and periodontitis.
PB  - Tramaniglio, Italy: The Journal of Infection in Developing Countries Non-Profit organization
T2  - The Journal of Infection in Developing Countries
T1  - The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex
IS  - 5
VL  - 17
DO  - 10.3855/jidc.17740
SP  - 643
EP  - 648
ER  - 
@article{
author = "Tambur, Zoran and Aleksić, Ema and Čabrilo Lazić, Milana and Opačić, Dolores and Kalevski, Katarina and Puletić, Miljan and Avramov, Stevan and Biočanin, Vladimir",
year = "2023",
abstract = "This study aimed to investigate the possibility of applying the hyperlight fluid fusion essential complex in dental plaque control, and to evaluate the effectiveness of new and modern agents used for the prevention and early treatment of gingivitis. Methodology:  The  study  included  60  subjects  randomly  divided  into  two  groups.  The  control  group  was  assigned  to  0.12%  chlorhexidine  (CHX) mouth rinse, whereas the test group used a solution based on hyper-harmonized hydroxylated fullerene water complex (3HFWC), twice daily for 2 weeks. The plaque, gingivitis and bleeding scores were evaluated and recorded. Collected plaque samples were seeded on blood agar  and  incubated  aerobically  at  a  temperature  of  37  °C  for  24-48  hours.  In  order  to  isolate  anaerobic  bacteria,  samples  were  seeded  on  Schaedler Agar and incubated anaerobically at 37 °C for seven days. Serial dilutions in saline from 101 - 106 were made, and grown colonies were counted and identified using the matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) system. Results: The reduction in the number of bacteria was significant in both control and test groups. The reduction was greater in the control group compared to the experimental group, but without statistically significant difference.Conclusions: 3HFWC treatment causes significant reduction in the number of dental plaque microorganisms. Since 3HFWC solution exhibited a  bacteriostatic  effect  similar  to  chlorhexidine  it  could  be  an  adequate  addition  to  solution  of  a  growing  problem  in  prevention  and  early treatment of gingivitis and periodontitis.",
publisher = "Tramaniglio, Italy: The Journal of Infection in Developing Countries Non-Profit organization",
journal = "The Journal of Infection in Developing Countries",
title = "The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex",
number = "5",
volume = "17",
doi = "10.3855/jidc.17740",
pages = "643-648"
}
Tambur, Z., Aleksić, E., Čabrilo Lazić, M., Opačić, D., Kalevski, K., Puletić, M., Avramov, S.,& Biočanin, V.. (2023). The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex. in The Journal of Infection in Developing Countries
Tramaniglio, Italy: The Journal of Infection in Developing Countries Non-Profit organization., 17(5), 643-648.
https://doi.org/10.3855/jidc.17740
Tambur Z, Aleksić E, Čabrilo Lazić M, Opačić D, Kalevski K, Puletić M, Avramov S, Biočanin V. The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex. in The Journal of Infection in Developing Countries. 2023;17(5):643-648.
doi:10.3855/jidc.17740 .
Tambur, Zoran, Aleksić, Ema, Čabrilo Lazić, Milana, Opačić, Dolores, Kalevski, Katarina, Puletić, Miljan, Avramov, Stevan, Biočanin, Vladimir, "The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex" in The Journal of Infection in Developing Countries, 17, no. 5 (2023):643-648,
https://doi.org/10.3855/jidc.17740 . .
2

Research on the correct use of antibiotics in dentistry

Tambur, Zoran; Aleksić, Ema; Milutinović, Jovana; Avramov, Stevan; Malešević, Adam; Biočanin, Vladimir

(Herceg Novi: Faculty of management Herceg Novi, Montenegro, 2023)

TY  - CONF
AU  - Tambur, Zoran
AU  - Aleksić, Ema
AU  - Milutinović, Jovana
AU  - Avramov, Stevan
AU  - Malešević, Adam
AU  - Biočanin, Vladimir
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6655
AB  - Izbor antibiotika se zasniva na principu “najbolje pretpostavke“, uz poznavanje
infektivnog oboljenja, najverovatnijeg uzročnika i njegovog uobičajenog profila
osetljivosti na antibiotike. Ovakva empirijska antibiotska terapija se najčešće primenjuje
u stomatologiji jer je većina infekcija uzrokovana sa više uzročnika, u ovim infekcijama
najčešće su uključene anaerobne Gram-negativne bakterije i prilikom uzimanja uzoraka
teško je izbeći kontaminaciju uzorka sa kolonizujućom mikroflorom. Potrebno je
pridržavati se osnovnih principa pravilne primene antibiotika. Potrebno je utvrditi da li je
oboljenje infektivne etiologije, i ako jeste pre primene antibiotika uzeti uzorak za
mikrobiološki pregled. Više faktora može da utiče na izbor antibiotika: istorija bolesti,
alergijske reakcije, toksični efekti leka i prethodne antimikrobne terapije. Dozu je
potrebno odrediti unapred, pre primene, da bi se postigla dovoljna koncentracija
antibiotika na mestu infekcije. Pri tome je potrebno voditi računa o postojećim oštećenjima
organa. Način primene antibiotika zavisi od težine oboljenja pa se kod teških infekcija bira
parenteralni, intravenski put primene. Sve češće se zapažaju interakcije antibiotika sa
drugim lekovima, zbog uvođenja novih lekova u kliničku praksu, pa je neophodno i ovaj
faktor uzeti u obzir prilikom određivanja antimikrobne terapije. Odstupanja od ovih
principa mogu dovesti do raznih nepravilnosti i neželjenih reakcija u terapiji. Preterana
empirijska upotreba antibiotika dovela je do enormnog razvoja rezistencije bakterija na
ove agense pa je danas sužen izbor terapijskih mogućnosti za lečenje mnogih infekcija i
moraju se koristiti često manje efikasni agensi.
AB  - Antibiotics are chosen on a "best guess" basis, with knowledge of the
infectious disease, the most likely pathogen and its usual antibiotic susceptibility profile.
This type of empirical antibiotic therapy is used in most situations in dentistry because
most infections are caused by multiple pathogens, anaerobic gramme-negative bacteria
are most commonly involved in these infections, and it's difficult to avoid contamination
of the specimen with the colonising microflora when taking samples. It's important to
follow the basic principles of the correct use of antibiotics. It must be determined whether
the disease has an infectious cause and if so, a sample must be taken for microbiological
examination before antibiotics are administered. Several factors may influence the choice
of antibiotic: medical history, allergic reactions, toxic effects of the drug and previous
antimicrobial therapy. Existing organ damage must be taken into account. The way
antibiotics are administered depends on the severity of the disease. For example, the
parenteral, intravenous route of administration is chosen for severe infections.
Interactions of antibiotics with other drugs are becoming more common due to the
introduction of new drugs into clinical practise, so this factor must be considered when
determining antimicrobial therapy. The over-empirical use of antibiotics has led to a
tremendous development of bacterial resistance to these agents, so that today the choice
of therapeutic options for the treatment of many infections is limited to less effective
agents.
PB  - Herceg Novi: Faculty of management Herceg Novi, Montenegro
C3  - Proceedings Coast 2023: 2nd International Conference on Advances in Science and Technology: 2023 May 31 - Jun 3; Herceg Novi, Montenegro
T1  - Research on the correct use of antibiotics in dentistry
T1  - Istraživanje pravilne primene antibiotika u stomatologij
SP  - 492
EP  - 514
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6655
ER  - 
@conference{
author = "Tambur, Zoran and Aleksić, Ema and Milutinović, Jovana and Avramov, Stevan and Malešević, Adam and Biočanin, Vladimir",
year = "2023",
abstract = "Izbor antibiotika se zasniva na principu “najbolje pretpostavke“, uz poznavanje
infektivnog oboljenja, najverovatnijeg uzročnika i njegovog uobičajenog profila
osetljivosti na antibiotike. Ovakva empirijska antibiotska terapija se najčešće primenjuje
u stomatologiji jer je većina infekcija uzrokovana sa više uzročnika, u ovim infekcijama
najčešće su uključene anaerobne Gram-negativne bakterije i prilikom uzimanja uzoraka
teško je izbeći kontaminaciju uzorka sa kolonizujućom mikroflorom. Potrebno je
pridržavati se osnovnih principa pravilne primene antibiotika. Potrebno je utvrditi da li je
oboljenje infektivne etiologije, i ako jeste pre primene antibiotika uzeti uzorak za
mikrobiološki pregled. Više faktora može da utiče na izbor antibiotika: istorija bolesti,
alergijske reakcije, toksični efekti leka i prethodne antimikrobne terapije. Dozu je
potrebno odrediti unapred, pre primene, da bi se postigla dovoljna koncentracija
antibiotika na mestu infekcije. Pri tome je potrebno voditi računa o postojećim oštećenjima
organa. Način primene antibiotika zavisi od težine oboljenja pa se kod teških infekcija bira
parenteralni, intravenski put primene. Sve češće se zapažaju interakcije antibiotika sa
drugim lekovima, zbog uvođenja novih lekova u kliničku praksu, pa je neophodno i ovaj
faktor uzeti u obzir prilikom određivanja antimikrobne terapije. Odstupanja od ovih
principa mogu dovesti do raznih nepravilnosti i neželjenih reakcija u terapiji. Preterana
empirijska upotreba antibiotika dovela je do enormnog razvoja rezistencije bakterija na
ove agense pa je danas sužen izbor terapijskih mogućnosti za lečenje mnogih infekcija i
moraju se koristiti često manje efikasni agensi., Antibiotics are chosen on a "best guess" basis, with knowledge of the
infectious disease, the most likely pathogen and its usual antibiotic susceptibility profile.
This type of empirical antibiotic therapy is used in most situations in dentistry because
most infections are caused by multiple pathogens, anaerobic gramme-negative bacteria
are most commonly involved in these infections, and it's difficult to avoid contamination
of the specimen with the colonising microflora when taking samples. It's important to
follow the basic principles of the correct use of antibiotics. It must be determined whether
the disease has an infectious cause and if so, a sample must be taken for microbiological
examination before antibiotics are administered. Several factors may influence the choice
of antibiotic: medical history, allergic reactions, toxic effects of the drug and previous
antimicrobial therapy. Existing organ damage must be taken into account. The way
antibiotics are administered depends on the severity of the disease. For example, the
parenteral, intravenous route of administration is chosen for severe infections.
Interactions of antibiotics with other drugs are becoming more common due to the
introduction of new drugs into clinical practise, so this factor must be considered when
determining antimicrobial therapy. The over-empirical use of antibiotics has led to a
tremendous development of bacterial resistance to these agents, so that today the choice
of therapeutic options for the treatment of many infections is limited to less effective
agents.",
publisher = "Herceg Novi: Faculty of management Herceg Novi, Montenegro",
journal = "Proceedings Coast 2023: 2nd International Conference on Advances in Science and Technology: 2023 May 31 - Jun 3; Herceg Novi, Montenegro",
title = "Research on the correct use of antibiotics in dentistry, Istraživanje pravilne primene antibiotika u stomatologij",
pages = "492-514",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6655"
}
Tambur, Z., Aleksić, E., Milutinović, J., Avramov, S., Malešević, A.,& Biočanin, V.. (2023). Research on the correct use of antibiotics in dentistry. in Proceedings Coast 2023: 2nd International Conference on Advances in Science and Technology: 2023 May 31 - Jun 3; Herceg Novi, Montenegro
Herceg Novi: Faculty of management Herceg Novi, Montenegro., 492-514.
https://hdl.handle.net/21.15107/rcub_ibiss_6655
Tambur Z, Aleksić E, Milutinović J, Avramov S, Malešević A, Biočanin V. Research on the correct use of antibiotics in dentistry. in Proceedings Coast 2023: 2nd International Conference on Advances in Science and Technology: 2023 May 31 - Jun 3; Herceg Novi, Montenegro. 2023;:492-514.
https://hdl.handle.net/21.15107/rcub_ibiss_6655 .
Tambur, Zoran, Aleksić, Ema, Milutinović, Jovana, Avramov, Stevan, Malešević, Adam, Biočanin, Vladimir, "Research on the correct use of antibiotics in dentistry" in Proceedings Coast 2023: 2nd International Conference on Advances in Science and Technology: 2023 May 31 - Jun 3; Herceg Novi, Montenegro (2023):492-514,
https://hdl.handle.net/21.15107/rcub_ibiss_6655 .

Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic

Antonijević, Đorđe; Despotović, Ana; Biočanin, Vladimir; Milošević, Miloš; Trišić, Dijana; Lazović, Vladimir; Zogović, Nevena; Milašin, Jelena; Ilić, Dragan

(Oxford : Elsevier, 2021)

TY  - JOUR
AU  - Antonijević, Đorđe
AU  - Despotović, Ana
AU  - Biočanin, Vladimir
AU  - Milošević, Miloš
AU  - Trišić, Dijana
AU  - Lazović, Vladimir
AU  - Zogović, Nevena
AU  - Milašin, Jelena
AU  - Ilić, Dragan
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S0272884221020794
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4464
AB  - The purpose of this study was to investigate the influence of different radiopacifiers on the physicochemical and biological properties of novel calcium silicate based endodontic ceramic enriched with bioactive nano-particulated hydroxyapatite – ECHA. Namely, ECHA was used as a basis for mixing with the following radiopacifiers: strontium fluoride (SrF2), zirconium dioxide (ZrO2) and bismuth oxide (Bi2O3). For comparison, Portland cement (PC) and mineral trioxide aggregate (MTA) were used. The following physicochemical characteristics were examined: the radiopacity, setting time, compressive strength, porosity, wettability and pH value. The biocompatibility of the cements was assessed by crystal violet, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) and cell adhesion assays. The highest radiopacity was obtained for the ECHA + Bi2O3 mixture and MTA that were statistically significant in comparison to other materials (p < 0.05). Both initial and final setting times as well as compressive strengths were statistically lower for experimental cements than for PC and MTA (p < 0.05). The lowest total porosity was observed in the ECHA + ZrO2 group when compared with the other two experimental cements (p < 0.05), but not when compared with PC and MTA (p > 0.05). Experimental cements exhibited statistically higher contact angles of glycerol than PC and MTA (p < 0.05). For blood plasma, a statistical difference was found only between ECHA + Bi2O3 and PC (p < 0.05). All investigated materials had alkalization ability. Cell viability assays revealed that the extracts of tested cements did not exhibit cytotoxic effect on L929 cells. Scanning electron microscopy had shown a high degree of cell proliferation and adhesion of cells from apical papilla on experimental cements’ surfaces. Novel endodontic ceramics with nano-hydroxyapatite addition have satisfactory biological and physicochemical properties when compared to MTA and PC controls. Considerable lower setting time of experimental cements might present a huge advantage of these synthesized materials in clinical practice. SrF2 presents a novel promising radiopacifying agent for dental cements manufacturing.
PB  - Oxford : Elsevier
T2  - Ceramics International
T1  - Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic
IS  - 20
VL  - 47
DO  - 10.1016/j.ceramint.2021.07.052
SP  - 28913
EP  - 28923
ER  - 
@article{
author = "Antonijević, Đorđe and Despotović, Ana and Biočanin, Vladimir and Milošević, Miloš and Trišić, Dijana and Lazović, Vladimir and Zogović, Nevena and Milašin, Jelena and Ilić, Dragan",
year = "2021",
abstract = "The purpose of this study was to investigate the influence of different radiopacifiers on the physicochemical and biological properties of novel calcium silicate based endodontic ceramic enriched with bioactive nano-particulated hydroxyapatite – ECHA. Namely, ECHA was used as a basis for mixing with the following radiopacifiers: strontium fluoride (SrF2), zirconium dioxide (ZrO2) and bismuth oxide (Bi2O3). For comparison, Portland cement (PC) and mineral trioxide aggregate (MTA) were used. The following physicochemical characteristics were examined: the radiopacity, setting time, compressive strength, porosity, wettability and pH value. The biocompatibility of the cements was assessed by crystal violet, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) and cell adhesion assays. The highest radiopacity was obtained for the ECHA + Bi2O3 mixture and MTA that were statistically significant in comparison to other materials (p < 0.05). Both initial and final setting times as well as compressive strengths were statistically lower for experimental cements than for PC and MTA (p < 0.05). The lowest total porosity was observed in the ECHA + ZrO2 group when compared with the other two experimental cements (p < 0.05), but not when compared with PC and MTA (p > 0.05). Experimental cements exhibited statistically higher contact angles of glycerol than PC and MTA (p < 0.05). For blood plasma, a statistical difference was found only between ECHA + Bi2O3 and PC (p < 0.05). All investigated materials had alkalization ability. Cell viability assays revealed that the extracts of tested cements did not exhibit cytotoxic effect on L929 cells. Scanning electron microscopy had shown a high degree of cell proliferation and adhesion of cells from apical papilla on experimental cements’ surfaces. Novel endodontic ceramics with nano-hydroxyapatite addition have satisfactory biological and physicochemical properties when compared to MTA and PC controls. Considerable lower setting time of experimental cements might present a huge advantage of these synthesized materials in clinical practice. SrF2 presents a novel promising radiopacifying agent for dental cements manufacturing.",
publisher = "Oxford : Elsevier",
journal = "Ceramics International",
title = "Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic",
number = "20",
volume = "47",
doi = "10.1016/j.ceramint.2021.07.052",
pages = "28913-28923"
}
Antonijević, Đ., Despotović, A., Biočanin, V., Milošević, M., Trišić, D., Lazović, V., Zogović, N., Milašin, J.,& Ilić, D.. (2021). Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic. in Ceramics International
Oxford : Elsevier., 47(20), 28913-28923.
https://doi.org/10.1016/j.ceramint.2021.07.052
Antonijević Đ, Despotović A, Biočanin V, Milošević M, Trišić D, Lazović V, Zogović N, Milašin J, Ilić D. Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic. in Ceramics International. 2021;47(20):28913-28923.
doi:10.1016/j.ceramint.2021.07.052 .
Antonijević, Đorđe, Despotović, Ana, Biočanin, Vladimir, Milošević, Miloš, Trišić, Dijana, Lazović, Vladimir, Zogović, Nevena, Milašin, Jelena, Ilić, Dragan, "Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic" in Ceramics International, 47, no. 20 (2021):28913-28923,
https://doi.org/10.1016/j.ceramint.2021.07.052 . .
9
2
10

Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic

Antonijević, Đorđe; Despotović, Ana; Biočanin, Vladimir; Milošević, Miloš; Trišić, Dijana; Lazović, Vladimir; Zogović, Nevena; Milašin, Jelena; Ilić, Dragan

(Oxford: Elsevier Ltd, 2021)

TY  - JOUR
AU  - Antonijević, Đorđe
AU  - Despotović, Ana
AU  - Biočanin, Vladimir
AU  - Milošević, Miloš
AU  - Trišić, Dijana
AU  - Lazović, Vladimir
AU  - Zogović, Nevena
AU  - Milašin, Jelena
AU  - Ilić, Dragan
PY  - 2021
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0272884221020794
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4445
AB  - The purpose of this study was to investigate the influence of different radiopacifiers on the physicochemical and biological properties of novel calcium silicate based endodontic ceramic enriched with bioactive nano-particulated hydroxyapatite – ECHA. Namely, ECHA was used as a basis for mixing with the following radiopacifiers: strontium fluoride (SrF2), zirconium dioxide (ZrO2) and bismuth oxide (Bi2O3). For comparison, Portland cement (PC) and mineral trioxide aggregate (MTA) were used. The following physicochemical characteristics were examined: the radiopacity, setting time, compressive strength, porosity, wettability and pH value. The biocompatibility of the cements was assessed by crystal violet, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) and cell adhesion assays. The highest radiopacity was obtained for the ECHA + Bi2O3 mixture and MTA that were statistically significant in comparison to other materials (p < 0.05). Both initial and final setting times as well as compressive strengths were statistically lower for experimental cements than for PC and MTA (p < 0.05). The lowest total porosity was observed in the ECHA + ZrO2 group when compared with the other two experimental cements (p < 0.05), but not when compared with PC and MTA (p > 0.05). Experimental cements exhibited statistically higher contact angles of glycerol than PC and MTA (p < 0.05). For blood plasma, a statistical difference was found only between ECHA + Bi2O3 and PC (p < 0.05). All investigated materials had alkalization ability. Cell viability assays revealed that the extracts of tested cements did not exhibit cytotoxic effect on L929 cells. Scanning electron microscopy had shown a high degree of cell proliferation and adhesion of cells from apical papilla on experimental cements’ surfaces. Novel endodontic ceramics with nano-hydroxyapatite addition have satisfactory biological and physicochemical properties when compared to MTA and PC controls. Considerable lower setting time of experimental cements might present a huge advantage of these synthesized materials in clinical practice. SrF2 presents a novel promising radiopacifying agent for dental cements manufacturing.
PB  - Oxford: Elsevier Ltd
T2  - Ceramics International
T1  - Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic
IS  - 20
VL  - 47
DO  - 10.1016/j.ceramint.2021.07.052
SP  - 28913
EP  - 28923
ER  - 
@article{
author = "Antonijević, Đorđe and Despotović, Ana and Biočanin, Vladimir and Milošević, Miloš and Trišić, Dijana and Lazović, Vladimir and Zogović, Nevena and Milašin, Jelena and Ilić, Dragan",
year = "2021",
abstract = "The purpose of this study was to investigate the influence of different radiopacifiers on the physicochemical and biological properties of novel calcium silicate based endodontic ceramic enriched with bioactive nano-particulated hydroxyapatite – ECHA. Namely, ECHA was used as a basis for mixing with the following radiopacifiers: strontium fluoride (SrF2), zirconium dioxide (ZrO2) and bismuth oxide (Bi2O3). For comparison, Portland cement (PC) and mineral trioxide aggregate (MTA) were used. The following physicochemical characteristics were examined: the radiopacity, setting time, compressive strength, porosity, wettability and pH value. The biocompatibility of the cements was assessed by crystal violet, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) and cell adhesion assays. The highest radiopacity was obtained for the ECHA + Bi2O3 mixture and MTA that were statistically significant in comparison to other materials (p < 0.05). Both initial and final setting times as well as compressive strengths were statistically lower for experimental cements than for PC and MTA (p < 0.05). The lowest total porosity was observed in the ECHA + ZrO2 group when compared with the other two experimental cements (p < 0.05), but not when compared with PC and MTA (p > 0.05). Experimental cements exhibited statistically higher contact angles of glycerol than PC and MTA (p < 0.05). For blood plasma, a statistical difference was found only between ECHA + Bi2O3 and PC (p < 0.05). All investigated materials had alkalization ability. Cell viability assays revealed that the extracts of tested cements did not exhibit cytotoxic effect on L929 cells. Scanning electron microscopy had shown a high degree of cell proliferation and adhesion of cells from apical papilla on experimental cements’ surfaces. Novel endodontic ceramics with nano-hydroxyapatite addition have satisfactory biological and physicochemical properties when compared to MTA and PC controls. Considerable lower setting time of experimental cements might present a huge advantage of these synthesized materials in clinical practice. SrF2 presents a novel promising radiopacifying agent for dental cements manufacturing.",
publisher = "Oxford: Elsevier Ltd",
journal = "Ceramics International",
title = "Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic",
number = "20",
volume = "47",
doi = "10.1016/j.ceramint.2021.07.052",
pages = "28913-28923"
}
Antonijević, Đ., Despotović, A., Biočanin, V., Milošević, M., Trišić, D., Lazović, V., Zogović, N., Milašin, J.,& Ilić, D.. (2021). Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic. in Ceramics International
Oxford: Elsevier Ltd., 47(20), 28913-28923.
https://doi.org/10.1016/j.ceramint.2021.07.052
Antonijević Đ, Despotović A, Biočanin V, Milošević M, Trišić D, Lazović V, Zogović N, Milašin J, Ilić D. Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic. in Ceramics International. 2021;47(20):28913-28923.
doi:10.1016/j.ceramint.2021.07.052 .
Antonijević, Đorđe, Despotović, Ana, Biočanin, Vladimir, Milošević, Miloš, Trišić, Dijana, Lazović, Vladimir, Zogović, Nevena, Milašin, Jelena, Ilić, Dragan, "Influence of the addition of different radiopacifiers and bioactive nano-hydroxyapatite on physicochemical and biological properties of calcium silicate based endodontic ceramic" in Ceramics International, 47, no. 20 (2021):28913-28923,
https://doi.org/10.1016/j.ceramint.2021.07.052 . .
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Resistance to Antibiotics in Thermophilic Campylobacters.

Aleksić, Ema; Miljković-Selimović, Biljana; Tambur, Zoran; Aleksić, Nikola; Biočanin, Vladimir; Avramov, Stevan

(Lausanne: Frontiers Media S.A., 2021)

TY  - JOUR
AU  - Aleksić, Ema
AU  - Miljković-Selimović, Biljana
AU  - Tambur, Zoran
AU  - Aleksić, Nikola
AU  - Biočanin, Vladimir
AU  - Avramov, Stevan
PY  - 2021
UR  - https://www.frontiersin.org/articles/10.3389/fmed.2021.763434/full
UR  - http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC8632019
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4743
AB  - Campylobacter jejuni (C. jejuni) is one of the most frequent causes of bacterial enterocolitis globally. The disease in human is usually self-limiting, but when complications arise antibiotic therapy is required at a time when resistance to antibiotics is increasing worldwide. Mechanisms of antibiotic resistance in bacteria are diverse depending on antibiotic type and usage and include: enzymatic destruction or drug inactivation; alteration of the target enzyme; alteration of cell membrane permeability; alteration of ribosome structure and alteration of the metabolic pathway(s). Resistance of Campylobacter spp. to antibiotics, especially fluoroquinolones is now a major public health problem in developed and developing countries. In this review the mechanisms of resistance to fluoroquinolones, macrolides, tetracycline, aminoglycoside and the role of integrons in resistance of Campylobacter (especially at the molecular level) are discussed, as well as the mechanisms of resistance to β-lactam antibiotics, sulphonamides and trimethoprim. Multiple drug resistance is an increasing problem for treatment of campylobacter infections and emergence of resistant strains and resistance are important One Health issues.
PB  - Lausanne: Frontiers Media S.A.
T2  - Frontiers in Medicine
T1  - Resistance to Antibiotics in Thermophilic Campylobacters.
VL  - 8
DO  - 10.3389/fmed.2021.763434
SP  - 763434
ER  - 
@article{
author = "Aleksić, Ema and Miljković-Selimović, Biljana and Tambur, Zoran and Aleksić, Nikola and Biočanin, Vladimir and Avramov, Stevan",
year = "2021",
abstract = "Campylobacter jejuni (C. jejuni) is one of the most frequent causes of bacterial enterocolitis globally. The disease in human is usually self-limiting, but when complications arise antibiotic therapy is required at a time when resistance to antibiotics is increasing worldwide. Mechanisms of antibiotic resistance in bacteria are diverse depending on antibiotic type and usage and include: enzymatic destruction or drug inactivation; alteration of the target enzyme; alteration of cell membrane permeability; alteration of ribosome structure and alteration of the metabolic pathway(s). Resistance of Campylobacter spp. to antibiotics, especially fluoroquinolones is now a major public health problem in developed and developing countries. In this review the mechanisms of resistance to fluoroquinolones, macrolides, tetracycline, aminoglycoside and the role of integrons in resistance of Campylobacter (especially at the molecular level) are discussed, as well as the mechanisms of resistance to β-lactam antibiotics, sulphonamides and trimethoprim. Multiple drug resistance is an increasing problem for treatment of campylobacter infections and emergence of resistant strains and resistance are important One Health issues.",
publisher = "Lausanne: Frontiers Media S.A.",
journal = "Frontiers in Medicine",
title = "Resistance to Antibiotics in Thermophilic Campylobacters.",
volume = "8",
doi = "10.3389/fmed.2021.763434",
pages = "763434"
}
Aleksić, E., Miljković-Selimović, B., Tambur, Z., Aleksić, N., Biočanin, V.,& Avramov, S.. (2021). Resistance to Antibiotics in Thermophilic Campylobacters.. in Frontiers in Medicine
Lausanne: Frontiers Media S.A.., 8, 763434.
https://doi.org/10.3389/fmed.2021.763434
Aleksić E, Miljković-Selimović B, Tambur Z, Aleksić N, Biočanin V, Avramov S. Resistance to Antibiotics in Thermophilic Campylobacters.. in Frontiers in Medicine. 2021;8:763434.
doi:10.3389/fmed.2021.763434 .
Aleksić, Ema, Miljković-Selimović, Biljana, Tambur, Zoran, Aleksić, Nikola, Biočanin, Vladimir, Avramov, Stevan, "Resistance to Antibiotics in Thermophilic Campylobacters." in Frontiers in Medicine, 8 (2021):763434,
https://doi.org/10.3389/fmed.2021.763434 . .
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