TY  - CONF
AU  - Pergal, Marija
AU  - Brkljačić, Jelena
AU  - Pešić, Ivan
AU  - Dević, Gordana
AU  - Dojčinović, Biljana P.
AU  - Antić, Bratislav
AU  - Tovilović-Kovačević, Gordana
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6191
AB  - Polyurethane (PU) and PU nanocomposites with good biocompatibility and mechanical properties can be used as the biomedical matrix and tissue engineering biomaterials. Magnetic nanoparticles, especially ferrite nanoparticles have attracted much interest due to their specific physicochemical properties in various areas including magnetic recording, biosensing, catalyst, drug delivery systems, magnetic resonance imaging (MRI) and cancer therapy. Despite all these advantages, the nanoparticle agglomeration reduces the efficiency of the nanoparticles, so the nanoparticle incorporation into an appropriate polymeric matrix to prepare organic-inorganic nanocomposites is a right direction in the current scenario of biomedical nanotechnology. In this study, organic-inorganic PU nanocomposites based on zinc and copper ferrites and with the same composition of PU were prepared. The properties of PU nanocomposites were evaluated by nanoindentation, water contact angle and water absorption measurements. The presence of the nanoferrite nanoparticles affects properties of PU nanocomposites such as bulk morphology, mechanical, and biological properties. The biocompatibility of PU nanocomposites was investigated by MTT assay and cell attachment using endothelial cells. According to the results, the prepared PU nanocomposites with noncytotoxic chemistry could be a potential choice for vascular implants development.
PB  - Niš, Serbia: RAD Centre
C3  - Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro
T1  - Organic-inorganic nanocomposites for biomedical applications
DO  - 10.21175/rad.abstr.book.2023.19.20
SP  - 99
EP  - 99
ER  - 

@conference{
author = "Pergal, Marija and Brkljačić, Jelena and Pešić, Ivan and Dević, Gordana and Dojčinović, Biljana P. and Antić, Bratislav and Tovilović-Kovačević, Gordana",
year = "2023",
abstract = "Polyurethane (PU) and PU nanocomposites with good biocompatibility and mechanical properties can be used as the biomedical matrix and tissue engineering biomaterials. Magnetic nanoparticles, especially ferrite nanoparticles have attracted much interest due to their specific physicochemical properties in various areas including magnetic recording, biosensing, catalyst, drug delivery systems, magnetic resonance imaging (MRI) and cancer therapy. Despite all these advantages, the nanoparticle agglomeration reduces the efficiency of the nanoparticles, so the nanoparticle incorporation into an appropriate polymeric matrix to prepare organic-inorganic nanocomposites is a right direction in the current scenario of biomedical nanotechnology. In this study, organic-inorganic PU nanocomposites based on zinc and copper ferrites and with the same composition of PU were prepared. The properties of PU nanocomposites were evaluated by nanoindentation, water contact angle and water absorption measurements. The presence of the nanoferrite nanoparticles affects properties of PU nanocomposites such as bulk morphology, mechanical, and biological properties. The biocompatibility of PU nanocomposites was investigated by MTT assay and cell attachment using endothelial cells. According to the results, the prepared PU nanocomposites with noncytotoxic chemistry could be a potential choice for vascular implants development.",
publisher = "Niš, Serbia: RAD Centre",
journal = "Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro",
title = "Organic-inorganic nanocomposites for biomedical applications",
doi = "10.21175/rad.abstr.book.2023.19.20",
pages = "99-99"
}

Pergal, M., Brkljačić, J., Pešić, I., Dević, G., Dojčinović, B. P., Antić, B.,& Tovilović-Kovačević, G.. (2023). Organic-inorganic nanocomposites for biomedical applications. in Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro
Niš, Serbia: RAD Centre., 99-99.
https://doi.org/10.21175/rad.abstr.book.2023.19.20

Pergal M, Brkljačić J, Pešić I, Dević G, Dojčinović BP, Antić B, Tovilović-Kovačević G. Organic-inorganic nanocomposites for biomedical applications. in Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro. 2023;:99-99.
doi:10.21175/rad.abstr.book.2023.19.20 .

Pergal, Marija, Brkljačić, Jelena, Pešić, Ivan, Dević, Gordana, Dojčinović, Biljana P., Antić, Bratislav, Tovilović-Kovačević, Gordana, "Organic-inorganic nanocomposites for biomedical applications" in Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro (2023):99-99,
https://doi.org/10.21175/rad.abstr.book.2023.19.20 . .

TY  - CONF
AU  - Pergal, Marija
AU  - Brkljačić, Jelena
AU  - Tovilović-Kovačević, Gordana
AU  - Špirkova, Milena
AU  - Kodranov, Igor
AU  - Manojlović, Dragan
AU  - Knežević, Nenad
PY  - 2021
UR  - http://www.socphyschemserb.org/sr/publikacije/
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5732
AB  - Surface characteristics and biocompatibility of new nanocomposites based on polyurethane network
and mesoporous silica nanoparticles (PUMSNs) were investigated. Surface topography and
roughness coefficient were studied by AFM. Biocompatibility with endothelial cells and cytotoxicity
of the PUNs were assessed using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium
bromide) and cell adhesion assays. The addition of MSNs into polyurethane network led to
improvement of surface properties, as well as exhibited promising characteristics regarding adhesion
of cells, toward potential application in coating for medical devices.
PB  - Belgrade: Society of Physical Chemists of Serbia
C3  - Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia
T1  - Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials
SP  - 480
EP  - 482
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5732
ER  - 

@conference{
author = "Pergal, Marija and Brkljačić, Jelena and Tovilović-Kovačević, Gordana and Špirkova, Milena and Kodranov, Igor and Manojlović, Dragan and Knežević, Nenad",
year = "2021",
abstract = "Surface characteristics and biocompatibility of new nanocomposites based on polyurethane network
and mesoporous silica nanoparticles (PUMSNs) were investigated. Surface topography and
roughness coefficient were studied by AFM. Biocompatibility with endothelial cells and cytotoxicity
of the PUNs were assessed using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium
bromide) and cell adhesion assays. The addition of MSNs into polyurethane network led to
improvement of surface properties, as well as exhibited promising characteristics regarding adhesion
of cells, toward potential application in coating for medical devices.",
publisher = "Belgrade: Society of Physical Chemists of Serbia",
journal = "Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia",
title = "Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials",
pages = "480-482",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5732"
}

Pergal, M., Brkljačić, J., Tovilović-Kovačević, G., Špirkova, M., Kodranov, I., Manojlović, D.,& Knežević, N.. (2021). Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials. in Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia
Belgrade: Society of Physical Chemists of Serbia., 480-482.
https://hdl.handle.net/21.15107/rcub_ibiss_5732

Pergal M, Brkljačić J, Tovilović-Kovačević G, Špirkova M, Kodranov I, Manojlović D, Knežević N. Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials. in Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia. 2021;:480-482.
https://hdl.handle.net/21.15107/rcub_ibiss_5732 .

Pergal, Marija, Brkljačić, Jelena, Tovilović-Kovačević, Gordana, Špirkova, Milena, Kodranov, Igor, Manojlović, Dragan, Knežević, Nenad, "Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials" in Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia (2021):480-482,
https://hdl.handle.net/21.15107/rcub_ibiss_5732 .

TY  - JOUR
AU  - Kolarević, Stoimir
AU  - Aborgiba, Mustafa
AU  - Kračun-Kolarević, Margareta
AU  - Kostić, Jovana
AU  - Simonović, Predrag
AU  - Simić, Vladica
AU  - Milošković, Aleksandra
AU  - Reischer, Georg
AU  - Farnleitner, Andreas
AU  - Gačić, Zoran
AU  - Milačič, Radmila
AU  - Zuliani, Tea
AU  - Vidmar, Janja
AU  - Pergal, Marija
AU  - Piria, Marina
AU  - Paunović, Momir
AU  - Vuković-Gačić, Branka
PY  - 2016
UR  - http://dx.plos.org/10.1371/journal.pone.0162450
UR  - https://www.scopus.com/record/display.uri?eid=2-s2.0-84992314127&origin=SingleRecordEmailAlert&txGid=06CA159BD204EA9525A7DB2D67E8F57F.wsnAw8kcdt7IPYLO0V48gA:19
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2503
AB  - In this study we have performed a comprehensive genotoxicological survey along the 900 rkm of the Sava River. In total, 12 sites were chosen in compliance with the goals of GLOBAQUA project dealing with the effects of multiple stressors on biodiversity and functioning of aquatic ecosystems. The genotoxic potential was assessed using a complex battery of bioassays performed in prokaryotes and aquatic eukaryotes (freshwater fish). Battery comprised evaluation of mutagenicity by SOS/umuC test in Salmonella typhimuriumTA1535/ pSK1002. The level of DNA damage as a biomarker of exposure (comet assay) and biomarker of effect (micronucleus assay) and the level of oxidative stress as well (Fpg-modified comet assay) was studied in blood cells of bleak and spirlin (Alburnus alburnus/ Alburnoides bipunctatus respectively). Result indicated differential sensitivity of applied bioassays in detection of genotoxic pressure. The standard and Fpg-modified comet assay showed higher potential in differentiation of the sites based on genotoxic potential in comparison with micronucleus assay and SOS/umuC test. Our data represent snapshot of the current status of the river which indicates the presence of genotoxic potential along the river which can be traced to the deterioration of quality of the Sava River by communal and industrialwastewaters. The major highlight of the study is that we have provided complex set of data obtained from a single source (homogeneity of analyses for all samples).
T2  - Plos ONE
T1  - Evaluation of Genotoxic Pressure along the Sava River
IS  - 9
VL  - 11
DO  - 10.1371/journal.pone.0162450
SP  - e0162450
EP  - e0162450
ER  - 

@article{
author = "Kolarević, Stoimir and Aborgiba, Mustafa and Kračun-Kolarević, Margareta and Kostić, Jovana and Simonović, Predrag and Simić, Vladica and Milošković, Aleksandra and Reischer, Georg and Farnleitner, Andreas and Gačić, Zoran and Milačič, Radmila and Zuliani, Tea and Vidmar, Janja and Pergal, Marija and Piria, Marina and Paunović, Momir and Vuković-Gačić, Branka",
year = "2016",
abstract = "In this study we have performed a comprehensive genotoxicological survey along the 900 rkm of the Sava River. In total, 12 sites were chosen in compliance with the goals of GLOBAQUA project dealing with the effects of multiple stressors on biodiversity and functioning of aquatic ecosystems. The genotoxic potential was assessed using a complex battery of bioassays performed in prokaryotes and aquatic eukaryotes (freshwater fish). Battery comprised evaluation of mutagenicity by SOS/umuC test in Salmonella typhimuriumTA1535/ pSK1002. The level of DNA damage as a biomarker of exposure (comet assay) and biomarker of effect (micronucleus assay) and the level of oxidative stress as well (Fpg-modified comet assay) was studied in blood cells of bleak and spirlin (Alburnus alburnus/ Alburnoides bipunctatus respectively). Result indicated differential sensitivity of applied bioassays in detection of genotoxic pressure. The standard and Fpg-modified comet assay showed higher potential in differentiation of the sites based on genotoxic potential in comparison with micronucleus assay and SOS/umuC test. Our data represent snapshot of the current status of the river which indicates the presence of genotoxic potential along the river which can be traced to the deterioration of quality of the Sava River by communal and industrialwastewaters. The major highlight of the study is that we have provided complex set of data obtained from a single source (homogeneity of analyses for all samples).",
journal = "Plos ONE",
title = "Evaluation of Genotoxic Pressure along the Sava River",
number = "9",
volume = "11",
doi = "10.1371/journal.pone.0162450",
pages = "e0162450-e0162450"
}

Kolarević, S., Aborgiba, M., Kračun-Kolarević, M., Kostić, J., Simonović, P., Simić, V., Milošković, A., Reischer, G., Farnleitner, A., Gačić, Z., Milačič, R., Zuliani, T., Vidmar, J., Pergal, M., Piria, M., Paunović, M.,& Vuković-Gačić, B.. (2016). Evaluation of Genotoxic Pressure along the Sava River. in Plos ONE, 11(9), e0162450-e0162450.
https://doi.org/10.1371/journal.pone.0162450

Kolarević S, Aborgiba M, Kračun-Kolarević M, Kostić J, Simonović P, Simić V, Milošković A, Reischer G, Farnleitner A, Gačić Z, Milačič R, Zuliani T, Vidmar J, Pergal M, Piria M, Paunović M, Vuković-Gačić B. Evaluation of Genotoxic Pressure along the Sava River. in Plos ONE. 2016;11(9):e0162450-e0162450.
doi:10.1371/journal.pone.0162450 .

Kolarević, Stoimir, Aborgiba, Mustafa, Kračun-Kolarević, Margareta, Kostić, Jovana, Simonović, Predrag, Simić, Vladica, Milošković, Aleksandra, Reischer, Georg, Farnleitner, Andreas, Gačić, Zoran, Milačič, Radmila, Zuliani, Tea, Vidmar, Janja, Pergal, Marija, Piria, Marina, Paunović, Momir, Vuković-Gačić, Branka, "Evaluation of Genotoxic Pressure along the Sava River" in Plos ONE, 11, no. 9 (2016):e0162450-e0162450,
https://doi.org/10.1371/journal.pone.0162450 . .