TY  - JOUR
AU  - Tambur, Zoran
AU  - Aleksić, Ema
AU  - Čabrilo Lazić, Milana
AU  - Opačić, Dolores
AU  - Kalevski, Katarina
AU  - Puletić, Miljan
AU  - Avramov, Stevan
AU  - Biočanin, Vladimir
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6653
AB  - This study aimed to investigate the possibility of applying the hyperlight fluid fusion essential complex in dental plaque control, and to evaluate the effectiveness of new and modern agents used for the prevention and early treatment of gingivitis. Methodology:  The  study  included  60  subjects  randomly  divided  into  two  groups.  The  control  group  was  assigned  to  0.12%  chlorhexidine  (CHX) mouth rinse, whereas the test group used a solution based on hyper-harmonized hydroxylated fullerene water complex (3HFWC), twice daily for 2 weeks. The plaque, gingivitis and bleeding scores were evaluated and recorded. Collected plaque samples were seeded on blood agar  and  incubated  aerobically  at  a  temperature  of  37  °C  for  24-48  hours.  In  order  to  isolate  anaerobic  bacteria,  samples  were  seeded  on  Schaedler Agar and incubated anaerobically at 37 °C for seven days. Serial dilutions in saline from 101 - 106 were made, and grown colonies were counted and identified using the matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) system. Results: The reduction in the number of bacteria was significant in both control and test groups. The reduction was greater in the control group compared to the experimental group, but without statistically significant difference.Conclusions: 3HFWC treatment causes significant reduction in the number of dental plaque microorganisms. Since 3HFWC solution exhibited a  bacteriostatic  effect  similar  to  chlorhexidine  it  could  be  an  adequate  addition  to  solution  of  a  growing  problem  in  prevention  and  early treatment of gingivitis and periodontitis.
PB  - Tramaniglio, Italy: The Journal of Infection in Developing Countries Non-Profit organization
T2  - The Journal of Infection in Developing Countries
T1  - The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex
IS  - 5
VL  - 17
DO  - 10.3855/jidc.17740
SP  - 643
EP  - 648
ER  - 

@article{
author = "Tambur, Zoran and Aleksić, Ema and Čabrilo Lazić, Milana and Opačić, Dolores and Kalevski, Katarina and Puletić, Miljan and Avramov, Stevan and Biočanin, Vladimir",
year = "2023",
abstract = "This study aimed to investigate the possibility of applying the hyperlight fluid fusion essential complex in dental plaque control, and to evaluate the effectiveness of new and modern agents used for the prevention and early treatment of gingivitis. Methodology:  The  study  included  60  subjects  randomly  divided  into  two  groups.  The  control  group  was  assigned  to  0.12%  chlorhexidine  (CHX) mouth rinse, whereas the test group used a solution based on hyper-harmonized hydroxylated fullerene water complex (3HFWC), twice daily for 2 weeks. The plaque, gingivitis and bleeding scores were evaluated and recorded. Collected plaque samples were seeded on blood agar  and  incubated  aerobically  at  a  temperature  of  37  °C  for  24-48  hours.  In  order  to  isolate  anaerobic  bacteria,  samples  were  seeded  on  Schaedler Agar and incubated anaerobically at 37 °C for seven days. Serial dilutions in saline from 101 - 106 were made, and grown colonies were counted and identified using the matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) system. Results: The reduction in the number of bacteria was significant in both control and test groups. The reduction was greater in the control group compared to the experimental group, but without statistically significant difference.Conclusions: 3HFWC treatment causes significant reduction in the number of dental plaque microorganisms. Since 3HFWC solution exhibited a  bacteriostatic  effect  similar  to  chlorhexidine  it  could  be  an  adequate  addition  to  solution  of  a  growing  problem  in  prevention  and  early treatment of gingivitis and periodontitis.",
publisher = "Tramaniglio, Italy: The Journal of Infection in Developing Countries Non-Profit organization",
journal = "The Journal of Infection in Developing Countries",
title = "The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex",
number = "5",
volume = "17",
doi = "10.3855/jidc.17740",
pages = "643-648"
}

Tambur, Z., Aleksić, E., Čabrilo Lazić, M., Opačić, D., Kalevski, K., Puletić, M., Avramov, S.,& Biočanin, V.. (2023). The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex. in The Journal of Infection in Developing Countries
Tramaniglio, Italy: The Journal of Infection in Developing Countries Non-Profit organization., 17(5), 643-648.
https://doi.org/10.3855/jidc.17740

Tambur Z, Aleksić E, Čabrilo Lazić M, Opačić D, Kalevski K, Puletić M, Avramov S, Biočanin V. The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex. in The Journal of Infection in Developing Countries. 2023;17(5):643-648.
doi:10.3855/jidc.17740 .

Tambur, Zoran, Aleksić, Ema, Čabrilo Lazić, Milana, Opačić, Dolores, Kalevski, Katarina, Puletić, Miljan, Avramov, Stevan, Biočanin, Vladimir, "The investigation of antibacterial activity of hyperlight fluid fusion subcellular essential complex" in The Journal of Infection in Developing Countries, 17, no. 5 (2023):643-648,
https://doi.org/10.3855/jidc.17740 . .

TY  - JOUR
AU  - Vukovic, Branislava
AU  - Lazic, Zoran
AU  - Avramov, Stevan
AU  - Pavlović, Maja
AU  - Čabrilo-Lazić, Milana
AU  - Malešević, Adam
AU  - Trifunović, Jovanka
AU  - Nikolić, Živorad
PY  - 2022
UR  - http://www.doiserbia.nb.rs/Article.aspx?ID=0370-81792200047V
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5077
AB  - Introduction/Objective. Somatosensory evoked potentials are a neurophysiological tool for testing the effects of drugs in humans and animals. The aim of this study was to estimate the way that bromazepam and ibuprofen had on tooth pulp-evoked potentials (TPEPs) after non-painful stimuli, as well as to detect possible differences in this activity. Methods. Sixty young healthy subjects were included in the study. They were arranged into three groups: ibuprofen, bromazepam, and placebo. To record TPEPs response, dental pulp were electrically stimulated through intact enamel with non-painful stimuli. For stimulation and registration we used Xltek Protektor 32 system, software EPWorks, version 5.0 (Natus Medical Incorporated, Oakville, ON, Canada). The experiment consisted of two testing sessions. Five recordings were performed in each session. The first test session was before, and the second was 45 minutes after administration of a single dose of the ibuprofen (400 mg), bromazepam (1.5 mg) or placebo. Results. The results of the present study exhibit that both ibuprofen and bromazepam significantly increased all the latencies; ibuprofen decreased amplitudes of all the waves except the first one (p 0.05). Additionally, there were no significant differences in influence on TPEPs between bromazepam and ibuprofen (p > 0.05). Conclusion. Our study showed that both bromazepam and ibuprofen had the same influence on TPEPs after non-painful stimuli. That indicates that anxiolytic dose of bromazepam affects neurotransmission in the same manner as non-opioid analgesics ibuprofen.
PB  - Belgrade: Serbian Medical Society
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Comparison of bromazepam and ibuprofen influence on tooth pulp-evoked potentials in humans
IS  - 5-6
VL  - 150
DO  - 10.2298/SARH220131047V
SP  - 267
EP  - 273
ER  - 

@article{
author = "Vukovic, Branislava and Lazic, Zoran and Avramov, Stevan and Pavlović, Maja and Čabrilo-Lazić, Milana and Malešević, Adam and Trifunović, Jovanka and Nikolić, Živorad",
year = "2022",
abstract = "Introduction/Objective. Somatosensory evoked potentials are a neurophysiological tool for testing the effects of drugs in humans and animals. The aim of this study was to estimate the way that bromazepam and ibuprofen had on tooth pulp-evoked potentials (TPEPs) after non-painful stimuli, as well as to detect possible differences in this activity. Methods. Sixty young healthy subjects were included in the study. They were arranged into three groups: ibuprofen, bromazepam, and placebo. To record TPEPs response, dental pulp were electrically stimulated through intact enamel with non-painful stimuli. For stimulation and registration we used Xltek Protektor 32 system, software EPWorks, version 5.0 (Natus Medical Incorporated, Oakville, ON, Canada). The experiment consisted of two testing sessions. Five recordings were performed in each session. The first test session was before, and the second was 45 minutes after administration of a single dose of the ibuprofen (400 mg), bromazepam (1.5 mg) or placebo. Results. The results of the present study exhibit that both ibuprofen and bromazepam significantly increased all the latencies; ibuprofen decreased amplitudes of all the waves except the first one (p 0.05). Additionally, there were no significant differences in influence on TPEPs between bromazepam and ibuprofen (p > 0.05). Conclusion. Our study showed that both bromazepam and ibuprofen had the same influence on TPEPs after non-painful stimuli. That indicates that anxiolytic dose of bromazepam affects neurotransmission in the same manner as non-opioid analgesics ibuprofen.",
publisher = "Belgrade: Serbian Medical Society",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Comparison of bromazepam and ibuprofen influence on tooth pulp-evoked potentials in humans",
number = "5-6",
volume = "150",
doi = "10.2298/SARH220131047V",
pages = "267-273"
}

Vukovic, B., Lazic, Z., Avramov, S., Pavlović, M., Čabrilo-Lazić, M., Malešević, A., Trifunović, J.,& Nikolić, Ž.. (2022). Comparison of bromazepam and ibuprofen influence on tooth pulp-evoked potentials in humans. in Srpski arhiv za celokupno lekarstvo
Belgrade: Serbian Medical Society., 150(5-6), 267-273.
https://doi.org/10.2298/SARH220131047V

Vukovic B, Lazic Z, Avramov S, Pavlović M, Čabrilo-Lazić M, Malešević A, Trifunović J, Nikolić Ž. Comparison of bromazepam and ibuprofen influence on tooth pulp-evoked potentials in humans. in Srpski arhiv za celokupno lekarstvo. 2022;150(5-6):267-273.
doi:10.2298/SARH220131047V .

Vukovic, Branislava, Lazic, Zoran, Avramov, Stevan, Pavlović, Maja, Čabrilo-Lazić, Milana, Malešević, Adam, Trifunović, Jovanka, Nikolić, Živorad, "Comparison of bromazepam and ibuprofen influence on tooth pulp-evoked potentials in humans" in Srpski arhiv za celokupno lekarstvo, 150, no. 5-6 (2022):267-273,
https://doi.org/10.2298/SARH220131047V . .