TY  - JOUR
AU  - da Silva, Tamires Barlati Vieira
AU  - Dias, Maria Inês
AU  - Pereira, Carla
AU  - Mandim, Filipa
AU  - Ivanov, Marija
AU  - Soković, Marina
AU  - Ferreira, Isabel C. F. R.
AU  - Barros, Lillian
AU  - Seixas, Flávio Augusto Vicente
AU  - Bracht, Adelar
AU  - Peralta, Rosane Marina
PY  - 2023
UR  - http://xlink.rsc.org/?DOI=D2FO02442J
UR  - http://www.ncbi.nlm.nih.gov/pubmed/36723015
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5465
AB  - A variety of the classic green tea plant, Camellia sinensis, was developed and is exclusive to Kenya. Due to high content of anthocyanin polyphenols in its leaves, the beverage obtained from this variety is purple in color and is the origin of the name purple tea. This work had two main purposes. The first one was to identify and quantify the major anthocyanin polyphenols in a hot water aqueous extract of the purple tea leaves. The second one was to test the hypothesis if this extract is capable of inhibiting triglyceride absorption considering that anthocyanin polyphenolics have been frequently associated to antilipidemic effects. Parallel experiments were always done with a similar green tea extract for comparison purposes. The antioxidant, anti-inflammatory, and cytotoxic activities of both tea varieties are similar. The purple tea extract, however, was strongly inhibitory toward the pancreatic lipase (minimal IC50 = 67.4 μg mL-1), whereas the green tea preparation was a weak inhibitor. Triglyceride digestion in mice was inhibited by the purple tea extract starting at 100 mg kg-1 dose and with a well-defined dose dependence. Green tea had no effect on triglyceride digestion at doses up to 500 mg kg-1. The latter effect is probably caused by several components in the purple tea extract including non-anthocyanin and anthocyanin polyphenols, the first ones acting solely via the inhibition of the pancreatic lipase and the latter by inhibiting both the lipase and the transport of free fatty acids from the intestinal lumen into the circulating blood. The results suggest that the regular consumption of Kenyan purple tea can be useful in the control of obesity.
T2  - Food & Function
T1  - Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice
IS  - 3
VL  - 14
DO  - 10.1039/d2fo02442j
SP  - 1761
EP  - 1772
ER  - 

@article{
author = "da Silva, Tamires Barlati Vieira and Dias, Maria Inês and Pereira, Carla and Mandim, Filipa and Ivanov, Marija and Soković, Marina and Ferreira, Isabel C. F. R. and Barros, Lillian and Seixas, Flávio Augusto Vicente and Bracht, Adelar and Peralta, Rosane Marina",
year = "2023",
abstract = "A variety of the classic green tea plant, Camellia sinensis, was developed and is exclusive to Kenya. Due to high content of anthocyanin polyphenols in its leaves, the beverage obtained from this variety is purple in color and is the origin of the name purple tea. This work had two main purposes. The first one was to identify and quantify the major anthocyanin polyphenols in a hot water aqueous extract of the purple tea leaves. The second one was to test the hypothesis if this extract is capable of inhibiting triglyceride absorption considering that anthocyanin polyphenolics have been frequently associated to antilipidemic effects. Parallel experiments were always done with a similar green tea extract for comparison purposes. The antioxidant, anti-inflammatory, and cytotoxic activities of both tea varieties are similar. The purple tea extract, however, was strongly inhibitory toward the pancreatic lipase (minimal IC50 = 67.4 μg mL-1), whereas the green tea preparation was a weak inhibitor. Triglyceride digestion in mice was inhibited by the purple tea extract starting at 100 mg kg-1 dose and with a well-defined dose dependence. Green tea had no effect on triglyceride digestion at doses up to 500 mg kg-1. The latter effect is probably caused by several components in the purple tea extract including non-anthocyanin and anthocyanin polyphenols, the first ones acting solely via the inhibition of the pancreatic lipase and the latter by inhibiting both the lipase and the transport of free fatty acids from the intestinal lumen into the circulating blood. The results suggest that the regular consumption of Kenyan purple tea can be useful in the control of obesity.",
journal = "Food & Function",
title = "Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice",
number = "3",
volume = "14",
doi = "10.1039/d2fo02442j",
pages = "1761-1772"
}

da Silva, T. B. V., Dias, M. I., Pereira, C., Mandim, F., Ivanov, M., Soković, M., Ferreira, I. C. F. R., Barros, L., Seixas, F. A. V., Bracht, A.,& Peralta, R. M.. (2023). Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice. in Food & Function, 14(3), 1761-1772.
https://doi.org/10.1039/d2fo02442j

da Silva TBV, Dias MI, Pereira C, Mandim F, Ivanov M, Soković M, Ferreira ICFR, Barros L, Seixas FAV, Bracht A, Peralta RM. Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice. in Food & Function. 2023;14(3):1761-1772.
doi:10.1039/d2fo02442j .

da Silva, Tamires Barlati Vieira, Dias, Maria Inês, Pereira, Carla, Mandim, Filipa, Ivanov, Marija, Soković, Marina, Ferreira, Isabel C. F. R., Barros, Lillian, Seixas, Flávio Augusto Vicente, Bracht, Adelar, Peralta, Rosane Marina, "Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice" in Food & Function, 14, no. 3 (2023):1761-1772,
https://doi.org/10.1039/d2fo02442j . .

TY  - JOUR
AU  - Kissanga, Raquel
AU  - Liberal, Ângela
AU  - Diniz, Inês
AU  - Rodrigues, Ana S. B.
AU  - Baptista-Ferreira, João L.
AU  - Batista, Dora
AU  - Ivanov, Marija
AU  - Soković, Marina
AU  - Ferreira, Isabel C. F. R.
AU  - Fernandes, Ângela
AU  - Barros, Lillian
AU  - Catarino, Luís
PY  - 2022
UR  - https://www.mdpi.com/2304-8158/11/20/3240
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5179
AB  - The harvesting, processing, and sale of wild edible mushrooms (WEM) is a relevant economic activity in Angola and a good example of the use of non-wood forest products for food. Although there is deep traditional knowledge about the general properties of WEMs, a huge gap remains in detailed scientific knowledge. Thus, this study aimed to investigate the socio-economic importance of the species sold at local markets in Huila, Angola, from their molecular identification to the assessment of their nutritional, chemical, and bioactive profiles. From the eight WEM morphotypes studied, five were identified based on phenotypical and molecular approaches (four Russula spp., and Amanita loosei). The studied mushrooms proved to be a rich source of carbohydrates, proteins, and ashes, also presenting low amounts of fat. Chemical analyses further revealed mannitol as the main free sugar in all samples, and organic acids, namely, oxalic, quinic, malic, citric, and fumaric acids in low amounts. Additionally, the α-tocopherol isoform and monounsaturated fatty acids were predominant. Regarding phenolic acids, protocatechuic, p-hydroxybenzoic, p-coumaric, and cinnamic acids were detected in all mushroom hydroethanolic extracts, being responsible for their antioxidant, antibacterial, and antifungal activities. Our investigation contributes to the identification and knowledge of WEMs as important complementary food sources in Angola, some of which were reported for the first time, promoting their utilization as a basis of nutritional and functional ingredients, as being able to be part of a balanced diet and to be used in new bio-based formulations.
PB  - Basel: MDPI
T2  - Foods
T1  - Biochemical and Molecular Profiling of Wild Edible Mushrooms from Huila, Angola
IS  - 20
VL  - 11
DO  - 10.3390/foods11203240
SP  - 3240
ER  - 

@article{
author = "Kissanga, Raquel and Liberal, Ângela and Diniz, Inês and Rodrigues, Ana S. B. and Baptista-Ferreira, João L. and Batista, Dora and Ivanov, Marija and Soković, Marina and Ferreira, Isabel C. F. R. and Fernandes, Ângela and Barros, Lillian and Catarino, Luís",
year = "2022",
abstract = "The harvesting, processing, and sale of wild edible mushrooms (WEM) is a relevant economic activity in Angola and a good example of the use of non-wood forest products for food. Although there is deep traditional knowledge about the general properties of WEMs, a huge gap remains in detailed scientific knowledge. Thus, this study aimed to investigate the socio-economic importance of the species sold at local markets in Huila, Angola, from their molecular identification to the assessment of their nutritional, chemical, and bioactive profiles. From the eight WEM morphotypes studied, five were identified based on phenotypical and molecular approaches (four Russula spp., and Amanita loosei). The studied mushrooms proved to be a rich source of carbohydrates, proteins, and ashes, also presenting low amounts of fat. Chemical analyses further revealed mannitol as the main free sugar in all samples, and organic acids, namely, oxalic, quinic, malic, citric, and fumaric acids in low amounts. Additionally, the α-tocopherol isoform and monounsaturated fatty acids were predominant. Regarding phenolic acids, protocatechuic, p-hydroxybenzoic, p-coumaric, and cinnamic acids were detected in all mushroom hydroethanolic extracts, being responsible for their antioxidant, antibacterial, and antifungal activities. Our investigation contributes to the identification and knowledge of WEMs as important complementary food sources in Angola, some of which were reported for the first time, promoting their utilization as a basis of nutritional and functional ingredients, as being able to be part of a balanced diet and to be used in new bio-based formulations.",
publisher = "Basel: MDPI",
journal = "Foods",
title = "Biochemical and Molecular Profiling of Wild Edible Mushrooms from Huila, Angola",
number = "20",
volume = "11",
doi = "10.3390/foods11203240",
pages = "3240"
}

Kissanga, R., Liberal, Â., Diniz, I., Rodrigues, A. S. B., Baptista-Ferreira, J. L., Batista, D., Ivanov, M., Soković, M., Ferreira, I. C. F. R., Fernandes, Â., Barros, L.,& Catarino, L.. (2022). Biochemical and Molecular Profiling of Wild Edible Mushrooms from Huila, Angola. in Foods
Basel: MDPI., 11(20), 3240.
https://doi.org/10.3390/foods11203240

Kissanga R, Liberal Â, Diniz I, Rodrigues ASB, Baptista-Ferreira JL, Batista D, Ivanov M, Soković M, Ferreira ICFR, Fernandes Â, Barros L, Catarino L. Biochemical and Molecular Profiling of Wild Edible Mushrooms from Huila, Angola. in Foods. 2022;11(20):3240.
doi:10.3390/foods11203240 .

Kissanga, Raquel, Liberal, Ângela, Diniz, Inês, Rodrigues, Ana S. B., Baptista-Ferreira, João L., Batista, Dora, Ivanov, Marija, Soković, Marina, Ferreira, Isabel C. F. R., Fernandes, Ângela, Barros, Lillian, Catarino, Luís, "Biochemical and Molecular Profiling of Wild Edible Mushrooms from Huila, Angola" in Foods, 11, no. 20 (2022):3240,
https://doi.org/10.3390/foods11203240 . .

TY  - JOUR
AU  - Giordano, Miguel
AU  - Pinela, José
AU  - Dias, Maria Inês
AU  - Calhelha, Ricardo C.
AU  - Stojković, Dejan
AU  - Soković, Marina
AU  - Tavares, Débora
AU  - Cánepa, Analía Laura
AU  - Ferreira, Isabel C. F. R.
AU  - Caleja, Cristina
AU  - Barros, Lillian
PY  - 2021
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4393
AB  - The nutritional quality of kiwifruit has been highlighted by several studies, while its peel is typically discarded as a by-product with no commercial value. This study was carried out to optimize the ultrasound-assisted extraction (UAE) of phenolic compounds from kiwi peel. Three independent variables (time (t), ultrasonic power (P) and ethanol concentration (EtOH)) were combined in a five-level central composite rotatable design coupled with the response surface methodology (RSM). The extraction yield determined gravimetrically and the content of phenolic compounds identified by HPLC-DAD-ESI/MSn (namely two quercetin glycosides, one catechin isomer and one B-type (epi)catechin dimer) were the experimental responses used in the optimization. The polynomial models were successfully fitted to the experimental data and used to determine the optimal UAE conditions. The sonication of the sample at 94.4 W for 14.8 min, using 68.4% ethanol, resulted in a maximum of 1.51 ± 0.04 mg of flavonoids per g of extract, a result that allowed the experimental validation of the predictive model. The kiwi peel extract obtained under optimized conditions showed somehow promising bioactive properties, including antioxidant and antimicrobial effects, and no toxicity to Vero cells. Overall, this study contributes to the valorization of kiwi peel as a low-cost raw material for the development of natural ingredients (such as food preservatives) and also to the resource-use efficiency and circular bioeconomy.
PB  - Basel: MDPI
T2  - Applied Sciences
T1  - Ultrasound-assisted extraction of flavonoids from kiwi peel: Process optimization and bioactivity assessment
IS  - 14
VL  - 11
DO  - 10.3390/app11146416
SP  - 6416
ER  - 

@article{
author = "Giordano, Miguel and Pinela, José and Dias, Maria Inês and Calhelha, Ricardo C. and Stojković, Dejan and Soković, Marina and Tavares, Débora and Cánepa, Analía Laura and Ferreira, Isabel C. F. R. and Caleja, Cristina and Barros, Lillian",
year = "2021",
abstract = "The nutritional quality of kiwifruit has been highlighted by several studies, while its peel is typically discarded as a by-product with no commercial value. This study was carried out to optimize the ultrasound-assisted extraction (UAE) of phenolic compounds from kiwi peel. Three independent variables (time (t), ultrasonic power (P) and ethanol concentration (EtOH)) were combined in a five-level central composite rotatable design coupled with the response surface methodology (RSM). The extraction yield determined gravimetrically and the content of phenolic compounds identified by HPLC-DAD-ESI/MSn (namely two quercetin glycosides, one catechin isomer and one B-type (epi)catechin dimer) were the experimental responses used in the optimization. The polynomial models were successfully fitted to the experimental data and used to determine the optimal UAE conditions. The sonication of the sample at 94.4 W for 14.8 min, using 68.4% ethanol, resulted in a maximum of 1.51 ± 0.04 mg of flavonoids per g of extract, a result that allowed the experimental validation of the predictive model. The kiwi peel extract obtained under optimized conditions showed somehow promising bioactive properties, including antioxidant and antimicrobial effects, and no toxicity to Vero cells. Overall, this study contributes to the valorization of kiwi peel as a low-cost raw material for the development of natural ingredients (such as food preservatives) and also to the resource-use efficiency and circular bioeconomy.",
publisher = "Basel: MDPI",
journal = "Applied Sciences",
title = "Ultrasound-assisted extraction of flavonoids from kiwi peel: Process optimization and bioactivity assessment",
number = "14",
volume = "11",
doi = "10.3390/app11146416",
pages = "6416"
}

Giordano, M., Pinela, J., Dias, M. I., Calhelha, R. C., Stojković, D., Soković, M., Tavares, D., Cánepa, A. L., Ferreira, I. C. F. R., Caleja, C.,& Barros, L.. (2021). Ultrasound-assisted extraction of flavonoids from kiwi peel: Process optimization and bioactivity assessment. in Applied Sciences
Basel: MDPI., 11(14), 6416.
https://doi.org/10.3390/app11146416

Giordano M, Pinela J, Dias MI, Calhelha RC, Stojković D, Soković M, Tavares D, Cánepa AL, Ferreira ICFR, Caleja C, Barros L. Ultrasound-assisted extraction of flavonoids from kiwi peel: Process optimization and bioactivity assessment. in Applied Sciences. 2021;11(14):6416.
doi:10.3390/app11146416 .

Giordano, Miguel, Pinela, José, Dias, Maria Inês, Calhelha, Ricardo C., Stojković, Dejan, Soković, Marina, Tavares, Débora, Cánepa, Analía Laura, Ferreira, Isabel C. F. R., Caleja, Cristina, Barros, Lillian, "Ultrasound-assisted extraction of flavonoids from kiwi peel: Process optimization and bioactivity assessment" in Applied Sciences, 11, no. 14 (2021):6416,
https://doi.org/10.3390/app11146416 . .

TY  - JOUR
AU  - Petropoulos, Spyridon A.
AU  - Fernandes, Ângela
AU  - Calhelha, Ricardo C
AU  - Rouphael, Youssef
AU  - Petrović, Jovana
AU  - Soković, Marina
AU  - Ferreira, Isabel C.F.R.
AU  - Barros, Lillian
PY  - 2021
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4263
AB  - n the present study, the antimicrobial and cytotoxic activities, as well as the fatty acids composition in vegetable seed oils from linseed, purslane, luffa, and pumpkin were evaluated. For this purpose, two linseed oils and one luffa oil were commercially obtained, while purslane and pumpkin oils were obtained from own cultivated seeds. The results showed a variable fatty acids composition among the tested oils, with α-linolenic, linoleic, oleic, palmitic, and stearic acid being the most abundant compounds. In regards to particular oils, linseed oils were a rich source of α-linolenic acid, luffa and pumpkin oil were abundant in linoleic acid, while purslane oil presented a balanced composition with an almost similar amount of both fatty acids. Luffa oil was the most effective against two of the tested cancer cell lines, namely HeLa (cervical carcinoma) and NCI-H460 (non-small cell lung cancer), while it also showed moderate toxicity against non-tumor cells (PLP2 cell line). Regarding the antibacterial activity, linseed oil 3 and pumpkin oil showed the highest activity against most of the tested bacteria (especially against Enterobacter cloacae and Escherichia coli) with MIC and MBC values similar to the used positive controls (E211 and E224). All the tested oils showed significant antifungal activities, especially luffa and pumpkin oil, and for most of the tested fungi they were more effective than the positive controls, as for example in the case of Aspergillus versicolor, A. niger, and Penicillium verrucosum var. cyclopium. In conclusion, the results of our study showed promising antimicrobial and cytotoxic properties for the studied seed oils which could be partly attributed to their fatty acids composition, especially the long-chain ones with 12–18 carbons.
PB  - Basel: MDPI
T2  - Applied Sciences
T1  - Antimicrobial Properties, Cytotoxic Effects, and Fatty Acids Composition of Vegetable Oils from Purslane, Linseed, Luffa, and Pumpkin Seeds.
VL  - 11
DO  - 10.3390/app11125738
SP  - 5738
ER  - 

@article{
author = "Petropoulos, Spyridon A. and Fernandes, Ângela and Calhelha, Ricardo C and Rouphael, Youssef and Petrović, Jovana and Soković, Marina and Ferreira, Isabel C.F.R. and Barros, Lillian",
year = "2021",
abstract = "n the present study, the antimicrobial and cytotoxic activities, as well as the fatty acids composition in vegetable seed oils from linseed, purslane, luffa, and pumpkin were evaluated. For this purpose, two linseed oils and one luffa oil were commercially obtained, while purslane and pumpkin oils were obtained from own cultivated seeds. The results showed a variable fatty acids composition among the tested oils, with α-linolenic, linoleic, oleic, palmitic, and stearic acid being the most abundant compounds. In regards to particular oils, linseed oils were a rich source of α-linolenic acid, luffa and pumpkin oil were abundant in linoleic acid, while purslane oil presented a balanced composition with an almost similar amount of both fatty acids. Luffa oil was the most effective against two of the tested cancer cell lines, namely HeLa (cervical carcinoma) and NCI-H460 (non-small cell lung cancer), while it also showed moderate toxicity against non-tumor cells (PLP2 cell line). Regarding the antibacterial activity, linseed oil 3 and pumpkin oil showed the highest activity against most of the tested bacteria (especially against Enterobacter cloacae and Escherichia coli) with MIC and MBC values similar to the used positive controls (E211 and E224). All the tested oils showed significant antifungal activities, especially luffa and pumpkin oil, and for most of the tested fungi they were more effective than the positive controls, as for example in the case of Aspergillus versicolor, A. niger, and Penicillium verrucosum var. cyclopium. In conclusion, the results of our study showed promising antimicrobial and cytotoxic properties for the studied seed oils which could be partly attributed to their fatty acids composition, especially the long-chain ones with 12–18 carbons.",
publisher = "Basel: MDPI",
journal = "Applied Sciences",
title = "Antimicrobial Properties, Cytotoxic Effects, and Fatty Acids Composition of Vegetable Oils from Purslane, Linseed, Luffa, and Pumpkin Seeds.",
volume = "11",
doi = "10.3390/app11125738",
pages = "5738"
}

Petropoulos, S. A., Fernandes, Â., Calhelha, R. C., Rouphael, Y., Petrović, J., Soković, M., Ferreira, I. C.F.R.,& Barros, L.. (2021). Antimicrobial Properties, Cytotoxic Effects, and Fatty Acids Composition of Vegetable Oils from Purslane, Linseed, Luffa, and Pumpkin Seeds.. in Applied Sciences
Basel: MDPI., 11, 5738.
https://doi.org/10.3390/app11125738

Petropoulos SA, Fernandes Â, Calhelha RC, Rouphael Y, Petrović J, Soković M, Ferreira IC, Barros L. Antimicrobial Properties, Cytotoxic Effects, and Fatty Acids Composition of Vegetable Oils from Purslane, Linseed, Luffa, and Pumpkin Seeds.. in Applied Sciences. 2021;11:5738.
doi:10.3390/app11125738 .

Petropoulos, Spyridon A., Fernandes, Ângela, Calhelha, Ricardo C, Rouphael, Youssef, Petrović, Jovana, Soković, Marina, Ferreira, Isabel C.F.R., Barros, Lillian, "Antimicrobial Properties, Cytotoxic Effects, and Fatty Acids Composition of Vegetable Oils from Purslane, Linseed, Luffa, and Pumpkin Seeds." in Applied Sciences, 11 (2021):5738,
https://doi.org/10.3390/app11125738 . .

TY  - JOUR
AU  - Stojković, Dejan
AU  - Ivanov, Marija
AU  - Ćirić, Ana
AU  - Glamočlija, Jasmina
AU  - Van Griensven, L.
AU  - Ferreira, I.C.F.R.
AU  - Soković, Marina
PY  - 2019
UR  - https://www.sciencedirect.com/science/article/pii/S0254629917314205?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3245
AB  - As a continuation of our search for biologically active mushroom species the present study investigates in vitro antidiabetic properties of six edible and medicinal mushroom species: Agaricus blazei Murrill, Coprinus comatus (O.F. Müll.) Pers., Cordyceps militaris (L.) Fr., Inonotus obliquus (Ach. ex Pers.) Pilát, Morchella conica Pers. and Phellinus linteus Berk. & M.A. Curtis. In vitro assays on α-amylase and α-glucosidase enzymes inhibition were performed with methanolic extracts of the selected mushrooms. Furthermore, we calculated the necessary daily intake of mushroom extracts and dry mushroom powders based on the equivalent doses of therapeutic drug acarbose given to diabetic patients per day. Our comparative study on enzymes inhibition showed that the most promising potential is ascribed to Inonotus obliquus extract, while no inhibition of α-amylase was recorded with Morchella conica and Cordyceps militaris methanolic extract at the tested concentration. This comparative study is the first highlighting in vitro antidiabetic potential by inhibition of α-amylase and α-glucosidase with methanolic extracts; which makes the investigated species more promising for the diabetes type-2 treatment by an additional and different mechanism of action.
T2  - South African Journal of Botany
T1  - An insight into antidiabetic properties of six medicinal and edible mushrooms: Inhibition of α-amylase and α-glucosidase linked to type-2 diabetes
VL  - 120
DO  - 10.1016/J.SAJB.2018.01.007
SP  - 100
EP  - 103
ER  - 

@article{
author = "Stojković, Dejan and Ivanov, Marija and Ćirić, Ana and Glamočlija, Jasmina and Van Griensven, L. and Ferreira, I.C.F.R. and Soković, Marina",
year = "2019",
abstract = "As a continuation of our search for biologically active mushroom species the present study investigates in vitro antidiabetic properties of six edible and medicinal mushroom species: Agaricus blazei Murrill, Coprinus comatus (O.F. Müll.) Pers., Cordyceps militaris (L.) Fr., Inonotus obliquus (Ach. ex Pers.) Pilát, Morchella conica Pers. and Phellinus linteus Berk. & M.A. Curtis. In vitro assays on α-amylase and α-glucosidase enzymes inhibition were performed with methanolic extracts of the selected mushrooms. Furthermore, we calculated the necessary daily intake of mushroom extracts and dry mushroom powders based on the equivalent doses of therapeutic drug acarbose given to diabetic patients per day. Our comparative study on enzymes inhibition showed that the most promising potential is ascribed to Inonotus obliquus extract, while no inhibition of α-amylase was recorded with Morchella conica and Cordyceps militaris methanolic extract at the tested concentration. This comparative study is the first highlighting in vitro antidiabetic potential by inhibition of α-amylase and α-glucosidase with methanolic extracts; which makes the investigated species more promising for the diabetes type-2 treatment by an additional and different mechanism of action.",
journal = "South African Journal of Botany",
title = "An insight into antidiabetic properties of six medicinal and edible mushrooms: Inhibition of α-amylase and α-glucosidase linked to type-2 diabetes",
volume = "120",
doi = "10.1016/J.SAJB.2018.01.007",
pages = "100-103"
}

Stojković, D., Ivanov, M., Ćirić, A., Glamočlija, J., Van Griensven, L., Ferreira, I.C.F.R.,& Soković, M.. (2019). An insight into antidiabetic properties of six medicinal and edible mushrooms: Inhibition of α-amylase and α-glucosidase linked to type-2 diabetes. in South African Journal of Botany, 120, 100-103.
https://doi.org/10.1016/J.SAJB.2018.01.007

Stojković D, Ivanov M, Ćirić A, Glamočlija J, Van Griensven L, Ferreira I, Soković M. An insight into antidiabetic properties of six medicinal and edible mushrooms: Inhibition of α-amylase and α-glucosidase linked to type-2 diabetes. in South African Journal of Botany. 2019;120:100-103.
doi:10.1016/J.SAJB.2018.01.007 .

Stojković, Dejan, Ivanov, Marija, Ćirić, Ana, Glamočlija, Jasmina, Van Griensven, L., Ferreira, I.C.F.R., Soković, Marina, "An insight into antidiabetic properties of six medicinal and edible mushrooms: Inhibition of α-amylase and α-glucosidase linked to type-2 diabetes" in South African Journal of Botany, 120 (2019):100-103,
https://doi.org/10.1016/J.SAJB.2018.01.007 . .

TY  - CONF
AU  - Reis, F. S.
AU  - Stojković, Dejan
AU  - Barros, L.
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana
AU  - Soković, Marina
AU  - Martins, A.
AU  - Vasconcelos, M. H.
AU  - Morales, P.
AU  - Ferreira, I. C. F. R.
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2126
C3  - Planta Medica
T1  - Suillus granulatus (L.) Roussel as a source of bioactive compounds:
 Comparative study between mushrooms from different origins
IS  - 16
VL  - 80
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_2126
ER  - 

@conference{
author = "Reis, F. S. and Stojković, Dejan and Barros, L. and Glamočlija, Jasmina and Ćirić, Ana and Soković, Marina and Martins, A. and Vasconcelos, M. H. and Morales, P. and Ferreira, I. C. F. R.",
year = "2014",
journal = "Planta Medica",
title = "Suillus granulatus (L.) Roussel as a source of bioactive compounds:
 Comparative study between mushrooms from different origins",
number = "16",
volume = "80",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_2126"
}

Reis, F. S., Stojković, D., Barros, L., Glamočlija, J., Ćirić, A., Soković, M., Martins, A., Vasconcelos, M. H., Morales, P.,& Ferreira, I. C. F. R.. (2014). Suillus granulatus (L.) Roussel as a source of bioactive compounds:
 Comparative study between mushrooms from different origins. in Planta Medica, 80(16).
https://hdl.handle.net/21.15107/rcub_ibiss_2126

Reis FS, Stojković D, Barros L, Glamočlija J, Ćirić A, Soković M, Martins A, Vasconcelos MH, Morales P, Ferreira ICFR. Suillus granulatus (L.) Roussel as a source of bioactive compounds:
 Comparative study between mushrooms from different origins. in Planta Medica. 2014;80(16).
https://hdl.handle.net/21.15107/rcub_ibiss_2126 .

Reis, F. S., Stojković, Dejan, Barros, L., Glamočlija, Jasmina, Ćirić, Ana, Soković, Marina, Martins, A., Vasconcelos, M. H., Morales, P., Ferreira, I. C. F. R., "Suillus granulatus (L.) Roussel as a source of bioactive compounds:
 Comparative study between mushrooms from different origins" in Planta Medica, 80, no. 16 (2014),
https://hdl.handle.net/21.15107/rcub_ibiss_2126 .