TY  - JOUR
AU  - Stevanović, Jevrosima
AU  - Stanimirović, Zoran
AU  - Simeunović, Predrag
AU  - Lakić, Nada
AU  - Radović, Ivica
AU  - Soković, Marina
AU  - Griensven, Leo J L D VAN
PY  - 2018
UR  - http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000100219&lng=en&tlng=en
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3067
AB  - This study was done to discover any beneficial effect of a medicinal mushroom Agaricus brasiliensis extract on the honey bee. Firstly, a laboratory experiment was conducted on 640 bees reared in 32 single-use plastic rearing cups. A. brasiliensis extract proved safe in all doses tested (50, 100 and 150 mg/kg/day) irrespective of feeding mode (sugar syrup or candy). Secondly, a three-year field experiment was conducted on 26 colonies treated with a single dose of A. brasiliensis extract (100 mg/kg/day) added to syrup. Each year the colonies were treated once in autumn and twice in spring. The treatments significantly increased colony strength parameters: brood rearing improvement and adult population growth were noticed more often than the increase in honey production and pollen reserves. These positive effects were mainly observed in April. In conclusion, A. brasiliensis extract is safe for the bees and helps maintaining strong colonies, especially in spring.
T2  - Anais da Academia Brasileira de Ciencias
T1  - The effect of Agaricus brasiliensis extract supplementation on honey bee colonies.
IS  - 1
VL  - 90
DO  - 10.1590/0001-3765201820150182
SP  - 219
EP  - 229
ER  - 

@article{
author = "Stevanović, Jevrosima and Stanimirović, Zoran and Simeunović, Predrag and Lakić, Nada and Radović, Ivica and Soković, Marina and Griensven, Leo J L D VAN",
year = "2018",
abstract = "This study was done to discover any beneficial effect of a medicinal mushroom Agaricus brasiliensis extract on the honey bee. Firstly, a laboratory experiment was conducted on 640 bees reared in 32 single-use plastic rearing cups. A. brasiliensis extract proved safe in all doses tested (50, 100 and 150 mg/kg/day) irrespective of feeding mode (sugar syrup or candy). Secondly, a three-year field experiment was conducted on 26 colonies treated with a single dose of A. brasiliensis extract (100 mg/kg/day) added to syrup. Each year the colonies were treated once in autumn and twice in spring. The treatments significantly increased colony strength parameters: brood rearing improvement and adult population growth were noticed more often than the increase in honey production and pollen reserves. These positive effects were mainly observed in April. In conclusion, A. brasiliensis extract is safe for the bees and helps maintaining strong colonies, especially in spring.",
journal = "Anais da Academia Brasileira de Ciencias",
title = "The effect of Agaricus brasiliensis extract supplementation on honey bee colonies.",
number = "1",
volume = "90",
doi = "10.1590/0001-3765201820150182",
pages = "219-229"
}

Stevanović, J., Stanimirović, Z., Simeunović, P., Lakić, N., Radović, I., Soković, M.,& Griensven, L. J. L. D. V.. (2018). The effect of Agaricus brasiliensis extract supplementation on honey bee colonies.. in Anais da Academia Brasileira de Ciencias, 90(1), 219-229.
https://doi.org/10.1590/0001-3765201820150182

Stevanović J, Stanimirović Z, Simeunović P, Lakić N, Radović I, Soković M, Griensven LJLDV. The effect of Agaricus brasiliensis extract supplementation on honey bee colonies.. in Anais da Academia Brasileira de Ciencias. 2018;90(1):219-229.
doi:10.1590/0001-3765201820150182 .

Stevanović, Jevrosima, Stanimirović, Zoran, Simeunović, Predrag, Lakić, Nada, Radović, Ivica, Soković, Marina, Griensven, Leo J L D VAN, "The effect of Agaricus brasiliensis extract supplementation on honey bee colonies." in Anais da Academia Brasileira de Ciencias, 90, no. 1 (2018):219-229,
https://doi.org/10.1590/0001-3765201820150182 . .

TY  - JOUR
AU  - Bošnjak-Neumüller, Jasna
AU  - Radaković, Milena
AU  - Djelić, Ninoslav
AU  - Vuković-Gačić, Branka
AU  - Stevanović, Zora Dajić
AU  - Kolarević, Stoimir
AU  - Mišić, Danijela
AU  - Stanković, Milan
AU  - Knežević-Vukčević, Jelena
AU  - Spremo-Potparević, Biljana
AU  - Stanimirović, Zoran
PY  - 2017
UR  - http://www.ncbi.nlm.nih.gov/pubmed/28650332
UR  - http://www.pjps.pk/wp-content/uploads/pdfs/30/2/Supplementary/13-SUP-652.pdf
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3537
AB  - The success of antioxidant therapy in hyperthyroidism implies that disease is mediated by oxidative stress, which is known as one of the causing agents of ageing, degenerative diseases, and cancer. The main objective of our study was to determine possible protective effects of methanolic extract of N. rtanjensis in triiodothyronine (T3)-induced DNA breaks of human lymphocytes under in vitro conditions, based upon plant antioxidant capacity related to its phytochemical profile, mainly its polyphenolic complex. The total phenolic and flavonoid content and the antioxidant activity using in vitro 1,1-dyphenyl-2- picrylhydrazyl reagent (DPPH) was determined in methanolic extracts of plant leaves and flowers. The phenolic compound content of 62.73±1.80mg of GaA/g, exhibited solid antioxidant activity (IC50= 112.59±0.95μg/ml). The antigenotoxic activity of 0.2, 0.5 and 1.0mg/ml N. rtanjensis methanol extracts mixture with 100µM of T3 was studied in human lymphocytes in vitro using the Comet assay. It is supposed that the antigenotoxicity of N. rtanjensis methanol extracts was caused by high presence of chlorogenic acid, rosmarinic acid and rutin, all known as efficient antioxidant bioactive compounds, which were determined by ultrahigh-pressure liquid chromatograph with MS/MS Mass Spectroscopy (UHPLC/-HESI-MS / MS).
T2  - Pakistan Journal of Pharmaceutical Sciences
T1  - Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition, antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes.
IS  - 2(Suppl.)
VL  - 30
SP  - 625
EP  - 634
UR  - https://hdl.handle.net/21.15107/rcub_agrospace_4504
ER  - 

@article{
author = "Bošnjak-Neumüller, Jasna and Radaković, Milena and Djelić, Ninoslav and Vuković-Gačić, Branka and Stevanović, Zora Dajić and Kolarević, Stoimir and Mišić, Danijela and Stanković, Milan and Knežević-Vukčević, Jelena and Spremo-Potparević, Biljana and Stanimirović, Zoran",
year = "2017",
abstract = "The success of antioxidant therapy in hyperthyroidism implies that disease is mediated by oxidative stress, which is known as one of the causing agents of ageing, degenerative diseases, and cancer. The main objective of our study was to determine possible protective effects of methanolic extract of N. rtanjensis in triiodothyronine (T3)-induced DNA breaks of human lymphocytes under in vitro conditions, based upon plant antioxidant capacity related to its phytochemical profile, mainly its polyphenolic complex. The total phenolic and flavonoid content and the antioxidant activity using in vitro 1,1-dyphenyl-2- picrylhydrazyl reagent (DPPH) was determined in methanolic extracts of plant leaves and flowers. The phenolic compound content of 62.73±1.80mg of GaA/g, exhibited solid antioxidant activity (IC50= 112.59±0.95μg/ml). The antigenotoxic activity of 0.2, 0.5 and 1.0mg/ml N. rtanjensis methanol extracts mixture with 100µM of T3 was studied in human lymphocytes in vitro using the Comet assay. It is supposed that the antigenotoxicity of N. rtanjensis methanol extracts was caused by high presence of chlorogenic acid, rosmarinic acid and rutin, all known as efficient antioxidant bioactive compounds, which were determined by ultrahigh-pressure liquid chromatograph with MS/MS Mass Spectroscopy (UHPLC/-HESI-MS / MS).",
journal = "Pakistan Journal of Pharmaceutical Sciences",
title = "Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition, antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes.",
number = "2(Suppl.)",
volume = "30",
pages = "625-634",
url = "https://hdl.handle.net/21.15107/rcub_agrospace_4504"
}

Bošnjak-Neumüller, J., Radaković, M., Djelić, N., Vuković-Gačić, B., Stevanović, Z. D., Kolarević, S., Mišić, D., Stanković, M., Knežević-Vukčević, J., Spremo-Potparević, B.,& Stanimirović, Z.. (2017). Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition, antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes.. in Pakistan Journal of Pharmaceutical Sciences, 30(2(Suppl.)), 625-634.
https://hdl.handle.net/21.15107/rcub_agrospace_4504

Bošnjak-Neumüller J, Radaković M, Djelić N, Vuković-Gačić B, Stevanović ZD, Kolarević S, Mišić D, Stanković M, Knežević-Vukčević J, Spremo-Potparević B, Stanimirović Z. Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition, antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes.. in Pakistan Journal of Pharmaceutical Sciences. 2017;30(2(Suppl.)):625-634.
https://hdl.handle.net/21.15107/rcub_agrospace_4504 .

Bošnjak-Neumüller, Jasna, Radaković, Milena, Djelić, Ninoslav, Vuković-Gačić, Branka, Stevanović, Zora Dajić, Kolarević, Stoimir, Mišić, Danijela, Stanković, Milan, Knežević-Vukčević, Jelena, Spremo-Potparević, Biljana, Stanimirović, Zoran, "Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition, antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes." in Pakistan Journal of Pharmaceutical Sciences, 30, no. 2(Suppl.) (2017):625-634,
https://hdl.handle.net/21.15107/rcub_agrospace_4504 .

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Korićanac, Goran
AU  - Vujanac, Ivan
AU  - Đorđević, Ana
AU  - Pantelić, Marija
AU  - Romić, Snježana
AU  - Stanimirović, Zoran
AU  - Kirovski, Danijela
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6086
AB  - We investigated the hypothesis that obesity in dairy cows enhanced expression of proteins involved in hepaticfatty acid uptake and metabolism. Sixteen Holstein-Friesian close-up cows were divided into 2 equal groupsbased on their body condition score (BCS) as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Intravenousglucose tolerance test (GTT) and liver biopsieswere carried out at day 10 before calving. Blood samples were collectedbefore (basal) and after glucose infusion, and glucose, insulin and non-esterified fatty acid (NEFA) levelswere determined at each sample point. In addition, β-hydroxybutyrate and triglycerides levels were measuredin the basal samples. The liver biopsieswere analyzed for total lipid content and protein expression of insulin receptorbeta (IRβ), fatty acid translocase (FAT/CD36) and sterol regulatory element-binding protein-1 (SREBP-1).Basal glucose and insulin were higher in high-BCS cows, which coincided with higher circulating triglyceridesand hepatic lipid content. Clearance rate and AUC for NEFA during GTT were higher in optimal-BCS cows. The developmentof insulin resistance and fatty liver in obese cows was paralleled by increased hepatic expression ofthe IRβ, CD36 and SREBP-1. These results suggest that increased expression of hepatic CD36 and SREBP-1 is relevantin the obesity-driven lipid accumulation in the liver of dairy cows during late gestation.
PB  - Elsevier
T2  - Research in Veterinary Science
T1  - Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression
VL  - 107
DO  - 10.1016/j.rvsc.2016.04.007
SP  - 16
EP  - 19
ER  - 

@article{
author = "Prodanović, Radiša and Korićanac, Goran and Vujanac, Ivan and Đorđević, Ana and Pantelić, Marija and Romić, Snježana and Stanimirović, Zoran and Kirovski, Danijela",
year = "2016",
abstract = "We investigated the hypothesis that obesity in dairy cows enhanced expression of proteins involved in hepaticfatty acid uptake and metabolism. Sixteen Holstein-Friesian close-up cows were divided into 2 equal groupsbased on their body condition score (BCS) as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Intravenousglucose tolerance test (GTT) and liver biopsieswere carried out at day 10 before calving. Blood samples were collectedbefore (basal) and after glucose infusion, and glucose, insulin and non-esterified fatty acid (NEFA) levelswere determined at each sample point. In addition, β-hydroxybutyrate and triglycerides levels were measuredin the basal samples. The liver biopsieswere analyzed for total lipid content and protein expression of insulin receptorbeta (IRβ), fatty acid translocase (FAT/CD36) and sterol regulatory element-binding protein-1 (SREBP-1).Basal glucose and insulin were higher in high-BCS cows, which coincided with higher circulating triglyceridesand hepatic lipid content. Clearance rate and AUC for NEFA during GTT were higher in optimal-BCS cows. The developmentof insulin resistance and fatty liver in obese cows was paralleled by increased hepatic expression ofthe IRβ, CD36 and SREBP-1. These results suggest that increased expression of hepatic CD36 and SREBP-1 is relevantin the obesity-driven lipid accumulation in the liver of dairy cows during late gestation.",
publisher = "Elsevier",
journal = "Research in Veterinary Science",
title = "Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression",
volume = "107",
doi = "10.1016/j.rvsc.2016.04.007",
pages = "16-19"
}

Prodanović, R., Korićanac, G., Vujanac, I., Đorđević, A., Pantelić, M., Romić, S., Stanimirović, Z.,& Kirovski, D.. (2016). Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression. in Research in Veterinary Science
Elsevier., 107, 16-19.
https://doi.org/10.1016/j.rvsc.2016.04.007

Prodanović R, Korićanac G, Vujanac I, Đorđević A, Pantelić M, Romić S, Stanimirović Z, Kirovski D. Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression. in Research in Veterinary Science. 2016;107:16-19.
doi:10.1016/j.rvsc.2016.04.007 .

Prodanović, Radiša, Korićanac, Goran, Vujanac, Ivan, Đorđević, Ana, Pantelić, Marija, Romić, Snježana, Stanimirović, Zoran, Kirovski, Danijela, "Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression" in Research in Veterinary Science, 107 (2016):16-19,
https://doi.org/10.1016/j.rvsc.2016.04.007 . .

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Korićanac, Goran
AU  - Vujanac, Ivan
AU  - Đorđević, Ana
AU  - Pantelić, Marija
AU  - Romić, Snježana
AU  - Stanimirović, Zoran
AU  - Kirovski, Danijela
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6085
AB  - We investigated the hypothesis that obesity in dairy cows enhanced expression of proteins involved in hepatic
fatty acid uptake and metabolism. Sixteen Holstein-Friesian close-up cows were divided into 2 equal groups
based on their body condition score (BCS) as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Intravenous
glucose tolerance test (GTT) and liver biopsieswere carried out at day 10 before calving. Blood samples were collected
before (basal) and after glucose infusion, and glucose, insulin and non-esterified fatty acid (NEFA) levels
were determined at each sample point. In addition, β-hydroxybutyrate and triglycerides levels were measured
in the basal samples. The liver biopsieswere analyzed for total lipid content and protein expression of insulin receptor
beta (IRβ), fatty acid translocase (FAT/CD36) and sterol regulatory element-binding protein-1 (SREBP-1).
Basal glucose and insulin were higher in high-BCS cows, which coincided with higher circulating triglycerides
and hepatic lipid content. Clearance rate and AUC for NEFA during GTT were higher in optimal-BCS cows. The development
of insulin resistance and fatty liver in obese cows was paralleled by increased hepatic expression of
the IRβ, CD36 and SREBP-1. These results suggest that increased expression of hepatic CD36 and SREBP-1 is relevant
in the obesity-driven lipid accumulation in the liver of dairy cows during late gestation.
PB  - Elsevier
T2  - Research in Veterinary Science
T1  - Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression
VL  - 107
DO  - 10.1016/j.rvsc.2016.04.007
SP  - 16
EP  - 19
ER  - 

@article{
author = "Prodanović, Radiša and Korićanac, Goran and Vujanac, Ivan and Đorđević, Ana and Pantelić, Marija and Romić, Snježana and Stanimirović, Zoran and Kirovski, Danijela",
year = "2016",
abstract = "We investigated the hypothesis that obesity in dairy cows enhanced expression of proteins involved in hepatic
fatty acid uptake and metabolism. Sixteen Holstein-Friesian close-up cows were divided into 2 equal groups
based on their body condition score (BCS) as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Intravenous
glucose tolerance test (GTT) and liver biopsieswere carried out at day 10 before calving. Blood samples were collected
before (basal) and after glucose infusion, and glucose, insulin and non-esterified fatty acid (NEFA) levels
were determined at each sample point. In addition, β-hydroxybutyrate and triglycerides levels were measured
in the basal samples. The liver biopsieswere analyzed for total lipid content and protein expression of insulin receptor
beta (IRβ), fatty acid translocase (FAT/CD36) and sterol regulatory element-binding protein-1 (SREBP-1).
Basal glucose and insulin were higher in high-BCS cows, which coincided with higher circulating triglycerides
and hepatic lipid content. Clearance rate and AUC for NEFA during GTT were higher in optimal-BCS cows. The development
of insulin resistance and fatty liver in obese cows was paralleled by increased hepatic expression of
the IRβ, CD36 and SREBP-1. These results suggest that increased expression of hepatic CD36 and SREBP-1 is relevant
in the obesity-driven lipid accumulation in the liver of dairy cows during late gestation.",
publisher = "Elsevier",
journal = "Research in Veterinary Science",
title = "Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression",
volume = "107",
doi = "10.1016/j.rvsc.2016.04.007",
pages = "16-19"
}

Prodanović, R., Korićanac, G., Vujanac, I., Đorđević, A., Pantelić, M., Romić, S., Stanimirović, Z.,& Kirovski, D.. (2016). Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression. in Research in Veterinary Science
Elsevier., 107, 16-19.
https://doi.org/10.1016/j.rvsc.2016.04.007

Prodanović R, Korićanac G, Vujanac I, Đorđević A, Pantelić M, Romić S, Stanimirović Z, Kirovski D. Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression. in Research in Veterinary Science. 2016;107:16-19.
doi:10.1016/j.rvsc.2016.04.007 .

Prodanović, Radiša, Korićanac, Goran, Vujanac, Ivan, Đorđević, Ana, Pantelić, Marija, Romić, Snježana, Stanimirović, Zoran, Kirovski, Danijela, "Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression" in Research in Veterinary Science, 107 (2016):16-19,
https://doi.org/10.1016/j.rvsc.2016.04.007 . .