TY  - JOUR
AU  - Sretenović, Jasmina
AU  - Ajdžanović, Vladimir
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Čorbić, Milena
AU  - Milošević, Verica
AU  - Jakovljević, Vladimir
AU  - Milosavljević, Zoran
PY  - 2018
UR  - https://www.sciencedirect.com/science/article/pii/S0065128118300382?via%3Dihub
UR  - http://www.ncbi.nlm.nih.gov/pubmed/29759662
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3059
AB  - Anabolic androgenic steroids (AASs) are synthetic analogs of testosterone often used by athletes to increase the skeletal muscle mass. Our goal was to examine the effects of physical activity and physical activity combined with supraphysiological doses of nandrolone on functional morphology of the quadriceps muscle. The study included 32 peripubertal Wistar rats, divided into 4 groups: control (T-N-), nandrolone (T-N+), physical activity (T+N-) and physical activity plus nandrolone (T+N+) groups. The T+N- and T+N+ group swam for 4 weeks, 1 h/day, 5 days/week. The T-N+ and T+N+ groups received nandolone decanoate (20 mg/kg b.w.) once per week, subcutaneously. Subsequently, the rats were sacrificed and muscle specimens were prepared for the processing. Tissue sections were histochemically and immunohistochemically stained, while the image analysis was used for quantification. Longitudinal diameter of quadriceps muscle cells was increased for 21% in T-N+, for 57% in T+N- and for 64% in T+N+ group while cross section muscle cell area was increased in T-N+ for 19%, in T+N- for 47% and in T+N+ group for 59%, compared to the control. Collagen fibers covered area was increased in T-N+ group for 36%, in T+N- for 109% and in T+N+ group for 159%, compared to the control. Erythrocyte depots were decreased in T-N+ group and increased in T+N- and T+N+ group, in comparison with T-N-. VEGF depots were increased in all treated groups. Chronic administration of supraphysiological doses of AASs alone or in combination with physical activity induces hypertrophy and significant changes in the quadriceps muscle tissue structure.
T2  - Acta Histochemica
T1  - Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.
DO  - 10.1016/j.acthis.2018.04.004
ER  - 

@article{
author = "Sretenović, Jasmina and Ajdžanović, Vladimir and Živković, Vladimir and Srejović, Ivan and Čorbić, Milena and Milošević, Verica and Jakovljević, Vladimir and Milosavljević, Zoran",
year = "2018",
abstract = "Anabolic androgenic steroids (AASs) are synthetic analogs of testosterone often used by athletes to increase the skeletal muscle mass. Our goal was to examine the effects of physical activity and physical activity combined with supraphysiological doses of nandrolone on functional morphology of the quadriceps muscle. The study included 32 peripubertal Wistar rats, divided into 4 groups: control (T-N-), nandrolone (T-N+), physical activity (T+N-) and physical activity plus nandrolone (T+N+) groups. The T+N- and T+N+ group swam for 4 weeks, 1 h/day, 5 days/week. The T-N+ and T+N+ groups received nandolone decanoate (20 mg/kg b.w.) once per week, subcutaneously. Subsequently, the rats were sacrificed and muscle specimens were prepared for the processing. Tissue sections were histochemically and immunohistochemically stained, while the image analysis was used for quantification. Longitudinal diameter of quadriceps muscle cells was increased for 21% in T-N+, for 57% in T+N- and for 64% in T+N+ group while cross section muscle cell area was increased in T-N+ for 19%, in T+N- for 47% and in T+N+ group for 59%, compared to the control. Collagen fibers covered area was increased in T-N+ group for 36%, in T+N- for 109% and in T+N+ group for 159%, compared to the control. Erythrocyte depots were decreased in T-N+ group and increased in T+N- and T+N+ group, in comparison with T-N-. VEGF depots were increased in all treated groups. Chronic administration of supraphysiological doses of AASs alone or in combination with physical activity induces hypertrophy and significant changes in the quadriceps muscle tissue structure.",
journal = "Acta Histochemica",
title = "Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.",
doi = "10.1016/j.acthis.2018.04.004"
}

Sretenović, J., Ajdžanović, V., Živković, V., Srejović, I., Čorbić, M., Milošević, V., Jakovljević, V.,& Milosavljević, Z.. (2018). Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.. in Acta Histochemica.
https://doi.org/10.1016/j.acthis.2018.04.004

Sretenović J, Ajdžanović V, Živković V, Srejović I, Čorbić M, Milošević V, Jakovljević V, Milosavljević Z. Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.. in Acta Histochemica. 2018;.
doi:10.1016/j.acthis.2018.04.004 .

Sretenović, Jasmina, Ajdžanović, Vladimir, Živković, Vladimir, Srejović, Ivan, Čorbić, Milena, Milošević, Verica, Jakovljević, Vladimir, Milosavljević, Zoran, "Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats." in Acta Histochemica (2018),
https://doi.org/10.1016/j.acthis.2018.04.004 . .

TY  - JOUR
AU  - Sretenović, Jasmina
AU  - Ajdžanović, Vladimir
AU  - Živković, Vladimir
AU  - Srejović, Ivan
AU  - Čorbić, Milena
AU  - Milošević, Verica
AU  - Jakovljević, Vladimir
AU  - Milosavljević, Zoran
PY  - 2018
UR  - https://www.sciencedirect.com/science/article/pii/S0065128118300382?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3085
AB  - Anabolic androgenic steroids (AASs) are synthetic analogs of testosterone often used by athletes to increase the skeletal muscle mass. Our goal was to examine the effects of physical activity and physical activity combined with supraphysiological doses of nandrolone on functional morphology of the quadriceps muscle. The study included 32 peripubertal Wistar rats, divided into 4 groups: control (T-N-), nandrolone (T-N+), physical activity (T+N-) and physical activity plus nandrolone (T+N+) groups. The T+N- and T+N+ group swam for 4 weeks, 1 h/day, 5 days/week. The T-N+ and T+N+ groups received nandolone decanoate (20 mg/kg b.w.) once per week, subcutaneously. Subsequently, the rats were sacrificed and muscle specimens were prepared for the processing. Tissue sections were histochemically and immunohistochemically stained, while the image analysis was used for quantification. Longitudinal diameter of quadriceps muscle cells was increased for 21% in T-N+, for 57% in T+N- and for 64% in T+N+ group while cross section muscle cell area was increased in T-N+ for 19%, in T+N- for 47% and in T+N+ group for 59%, compared to the control. Collagen fibers covered area was increased in T-N+ group for 36%, in T+N- for 109% and in T+N+ group for 159%, compared to the control. Erythrocyte depots were decreased in T-N+ group and increased in T+N- and T+N+ group, in comparison with T-N-. VEGF depots were increased in all treated groups. Chronic administration of supraphysiological doses of AASs alone or in combination with physical activity induces hypertrophy and significant changes in the quadriceps muscle tissue structure.
T2  - Acta Histochemica
T1  - Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.
IS  - 5
VL  - 120
DO  - 10.1016/j.acthis.2018.04.004
SP  - 429
EP  - 437
ER  - 

@article{
author = "Sretenović, Jasmina and Ajdžanović, Vladimir and Živković, Vladimir and Srejović, Ivan and Čorbić, Milena and Milošević, Verica and Jakovljević, Vladimir and Milosavljević, Zoran",
year = "2018",
abstract = "Anabolic androgenic steroids (AASs) are synthetic analogs of testosterone often used by athletes to increase the skeletal muscle mass. Our goal was to examine the effects of physical activity and physical activity combined with supraphysiological doses of nandrolone on functional morphology of the quadriceps muscle. The study included 32 peripubertal Wistar rats, divided into 4 groups: control (T-N-), nandrolone (T-N+), physical activity (T+N-) and physical activity plus nandrolone (T+N+) groups. The T+N- and T+N+ group swam for 4 weeks, 1 h/day, 5 days/week. The T-N+ and T+N+ groups received nandolone decanoate (20 mg/kg b.w.) once per week, subcutaneously. Subsequently, the rats were sacrificed and muscle specimens were prepared for the processing. Tissue sections were histochemically and immunohistochemically stained, while the image analysis was used for quantification. Longitudinal diameter of quadriceps muscle cells was increased for 21% in T-N+, for 57% in T+N- and for 64% in T+N+ group while cross section muscle cell area was increased in T-N+ for 19%, in T+N- for 47% and in T+N+ group for 59%, compared to the control. Collagen fibers covered area was increased in T-N+ group for 36%, in T+N- for 109% and in T+N+ group for 159%, compared to the control. Erythrocyte depots were decreased in T-N+ group and increased in T+N- and T+N+ group, in comparison with T-N-. VEGF depots were increased in all treated groups. Chronic administration of supraphysiological doses of AASs alone or in combination with physical activity induces hypertrophy and significant changes in the quadriceps muscle tissue structure.",
journal = "Acta Histochemica",
title = "Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.",
number = "5",
volume = "120",
doi = "10.1016/j.acthis.2018.04.004",
pages = "429-437"
}

Sretenović, J., Ajdžanović, V., Živković, V., Srejović, I., Čorbić, M., Milošević, V., Jakovljević, V.,& Milosavljević, Z.. (2018). Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.. in Acta Histochemica, 120(5), 429-437.
https://doi.org/10.1016/j.acthis.2018.04.004

Sretenović J, Ajdžanović V, Živković V, Srejović I, Čorbić M, Milošević V, Jakovljević V, Milosavljević Z. Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats.. in Acta Histochemica. 2018;120(5):429-437.
doi:10.1016/j.acthis.2018.04.004 .

Sretenović, Jasmina, Ajdžanović, Vladimir, Živković, Vladimir, Srejović, Ivan, Čorbić, Milena, Milošević, Verica, Jakovljević, Vladimir, Milosavljević, Zoran, "Nandrolone decanoate and physical activity affect quadriceps in peripubertal rats." in Acta Histochemica, 120, no. 5 (2018):429-437,
https://doi.org/10.1016/j.acthis.2018.04.004 . .