TY  - JOUR
AU  - Otašević, Vesna
AU  - Stančić, Ana
AU  - Korać, Aleksandra
AU  - Janković, Aleksandra
AU  - Korać, Bato
PY  - 2020
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/biof.1535
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3385
AB  - Infertility is a significant global health problem that currently affects one of six couples in reproductive age. The quality of male reproductive cells dramatically decreased over the last years and almost every aspect of modern life additionally worsen sperm functional parameters that consequently markedly increase male infertility. This clearly points out the importance of finding a new approach to treat male infertility. Redox signaling mediated by reactive oxygen, nitrogen and sulfur species (ROS, RNS, and RSS respectively), has appeared important for sperm reproductive function. Present review summarizes the current knowledge of ROS, RNS, and RSS in male reproductive biology and identifies potential targets for development of novel pharmacological and therapeutic approaches for male infertility by targeted therapeutic modulation of redox signaling.
T2  - BioFactors (Oxford, England)
T1  - Reactive oxygen, nitrogen, and sulfur species in human male fertility. A crossroad of cellular signaling and pathology.
IS  - 2
VL  - 46
DO  - 10.1002/biof.1535
SP  - 206
EP  - 219
ER  - 

@article{
author = "Otašević, Vesna and Stančić, Ana and Korać, Aleksandra and Janković, Aleksandra and Korać, Bato",
year = "2020",
abstract = "Infertility is a significant global health problem that currently affects one of six couples in reproductive age. The quality of male reproductive cells dramatically decreased over the last years and almost every aspect of modern life additionally worsen sperm functional parameters that consequently markedly increase male infertility. This clearly points out the importance of finding a new approach to treat male infertility. Redox signaling mediated by reactive oxygen, nitrogen and sulfur species (ROS, RNS, and RSS respectively), has appeared important for sperm reproductive function. Present review summarizes the current knowledge of ROS, RNS, and RSS in male reproductive biology and identifies potential targets for development of novel pharmacological and therapeutic approaches for male infertility by targeted therapeutic modulation of redox signaling.",
journal = "BioFactors (Oxford, England)",
title = "Reactive oxygen, nitrogen, and sulfur species in human male fertility. A crossroad of cellular signaling and pathology.",
number = "2",
volume = "46",
doi = "10.1002/biof.1535",
pages = "206-219"
}

Otašević, V., Stančić, A., Korać, A., Janković, A.,& Korać, B.. (2020). Reactive oxygen, nitrogen, and sulfur species in human male fertility. A crossroad of cellular signaling and pathology.. in BioFactors (Oxford, England), 46(2), 206-219.
https://doi.org/10.1002/biof.1535

Otašević V, Stančić A, Korać A, Janković A, Korać B. Reactive oxygen, nitrogen, and sulfur species in human male fertility. A crossroad of cellular signaling and pathology.. in BioFactors (Oxford, England). 2020;46(2):206-219.
doi:10.1002/biof.1535 .

Otašević, Vesna, Stančić, Ana, Korać, Aleksandra, Janković, Aleksandra, Korać, Bato, "Reactive oxygen, nitrogen, and sulfur species in human male fertility. A crossroad of cellular signaling and pathology." in BioFactors (Oxford, England), 46, no. 2 (2020):206-219,
https://doi.org/10.1002/biof.1535 . .

TY  - JOUR
AU  - Otašević, Vesna
AU  - Kalezić, Anđelika
AU  - Macanović, Biljana
AU  - Janković, Aleksandra
AU  - Stančić, Ana
AU  - Garalejić, Eliana
AU  - Korać, Aleksandra
AU  - Korać, Bato
PY  - 2019
UR  - https://www.tandfonline.com/doi/full/10.1080/19396368.2019.1600171
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3330
AB  - Protein expression/activity of antioxidative defense enzymes (AD) in seminal plasma of fertile men might be used as biomarkers of male fertility status. To test this concept, the present study examined the semen parameters of males among 14 normal idiopathic (normozoospermia) and 84 subnormal (teratozoospermia, oligoteratozoospermia, oligoasthenoteratozoospermia) infertile individuals\. We investigated levels of protein expression/activity of Cu, Zn superoxide dismutase (CuZnSOD), manganese superoxide dismutase (MnSOD), catalase and glutathione peroxidase (GSH-Px), their association with functional sperm parameters, as well as their potential to serve as biomarkers of specific sperm pathologies. Although the activity of CuZnSOD and protein expression of catalase were significantly correlated with several sperm parameters, underlying their potential role in etiology of various sperm abnormalities, investigation of their potential usefulness as a biomarker of semen quality showed that these AD enzymes could not distinguish subtle differences between various sperm pathologies. In contrast, GSH-Px activity was decreased in all groups with sperm pathologies and was a very good indicator of aberrations in functional sperm parameters, explaining up to 94.6% of infertility cases where functional sperm parameters were affected. Therefore, assessment of GSH-Px activity showed the potential to discriminate between infertile males with normal and subnormal semen characteristics and may prove useful in the evaluation of male (in)fertility. Abbreviations: AD: antioxidative defense; Cu, Zn SOD: copper, zinc superoxide dismutase; GSH-Px: glutathione peroxidase; MnSOD: manganese superoxide dismutase; NS: normospermia; OATS: oligoasthenoteratozoospermia; OTS: oligoteratozoospermia; ROC: receiver operating characteristic; ROS: reactive oxygen species; TS: teratozoospermia; WHO: world health organization.
T2  - Systems Biology in Reproductive Medicine
T1  - Evaluation of the antioxidative enzymes in the seminal plasma of infertile men: Contribution to classic semen quality analysis.
DO  - 10.1080/19396368.2019.1600171
ER  - 

@article{
author = "Otašević, Vesna and Kalezić, Anđelika and Macanović, Biljana and Janković, Aleksandra and Stančić, Ana and Garalejić, Eliana and Korać, Aleksandra and Korać, Bato",
year = "2019",
abstract = "Protein expression/activity of antioxidative defense enzymes (AD) in seminal plasma of fertile men might be used as biomarkers of male fertility status. To test this concept, the present study examined the semen parameters of males among 14 normal idiopathic (normozoospermia) and 84 subnormal (teratozoospermia, oligoteratozoospermia, oligoasthenoteratozoospermia) infertile individuals\. We investigated levels of protein expression/activity of Cu, Zn superoxide dismutase (CuZnSOD), manganese superoxide dismutase (MnSOD), catalase and glutathione peroxidase (GSH-Px), their association with functional sperm parameters, as well as their potential to serve as biomarkers of specific sperm pathologies. Although the activity of CuZnSOD and protein expression of catalase were significantly correlated with several sperm parameters, underlying their potential role in etiology of various sperm abnormalities, investigation of their potential usefulness as a biomarker of semen quality showed that these AD enzymes could not distinguish subtle differences between various sperm pathologies. In contrast, GSH-Px activity was decreased in all groups with sperm pathologies and was a very good indicator of aberrations in functional sperm parameters, explaining up to 94.6% of infertility cases where functional sperm parameters were affected. Therefore, assessment of GSH-Px activity showed the potential to discriminate between infertile males with normal and subnormal semen characteristics and may prove useful in the evaluation of male (in)fertility. Abbreviations: AD: antioxidative defense; Cu, Zn SOD: copper, zinc superoxide dismutase; GSH-Px: glutathione peroxidase; MnSOD: manganese superoxide dismutase; NS: normospermia; OATS: oligoasthenoteratozoospermia; OTS: oligoteratozoospermia; ROC: receiver operating characteristic; ROS: reactive oxygen species; TS: teratozoospermia; WHO: world health organization.",
journal = "Systems Biology in Reproductive Medicine",
title = "Evaluation of the antioxidative enzymes in the seminal plasma of infertile men: Contribution to classic semen quality analysis.",
doi = "10.1080/19396368.2019.1600171"
}

Otašević, V., Kalezić, A., Macanović, B., Janković, A., Stančić, A., Garalejić, E., Korać, A.,& Korać, B.. (2019). Evaluation of the antioxidative enzymes in the seminal plasma of infertile men: Contribution to classic semen quality analysis.. in Systems Biology in Reproductive Medicine.
https://doi.org/10.1080/19396368.2019.1600171

Otašević V, Kalezić A, Macanović B, Janković A, Stančić A, Garalejić E, Korać A, Korać B. Evaluation of the antioxidative enzymes in the seminal plasma of infertile men: Contribution to classic semen quality analysis.. in Systems Biology in Reproductive Medicine. 2019;.
doi:10.1080/19396368.2019.1600171 .

Otašević, Vesna, Kalezić, Anđelika, Macanović, Biljana, Janković, Aleksandra, Stančić, Ana, Garalejić, Eliana, Korać, Aleksandra, Korać, Bato, "Evaluation of the antioxidative enzymes in the seminal plasma of infertile men: Contribution to classic semen quality analysis." in Systems Biology in Reproductive Medicine (2019),
https://doi.org/10.1080/19396368.2019.1600171 . .

TY  - JOUR
AU  - Stančić, Ana
AU  - Janković, Aleksandra
AU  - Korać, Aleksandra
AU  - Buzadžić, Biljana
AU  - Otašević, Vesna
AU  - Korać, Bato
PY  - 2018
UR  - http://linkinghub.elsevier.com/retrieve/pii/S0047637417301252
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2859
AB  - The role of nitric oxide (NO) in cutaneous physiology/pathology became a growing research field since the discovery that almost all types of skin cells can synthetize this redox signaling molecule about 20 years ago. Now, it is evident that NO is an important player in skin physiological processes and in responses of cutaneous cells to external insults, while the impaired NO signaling has an important consequence in skin pathology. Skin disorders are common complications in diabetic conditions. Various metabolic/biochemical and immunological dysregulations in diabetic skin are tightly coupled with the disturbances in the redox state, primarily the ratio between NO and superoxide (O(cyrillic) 2 - ). This review describes possible therapeutic significance of different redox state modulators in the treatment of diabetic skin disorders. The focus is on those modulators that tightly control NO/O(cyrillic) 2 - ratio through the complex mechanisms affecting endogenous NO and O(cyrillic) 2 - producing and removing systems. The fact that classic antioxidants failed to show significant benefits in diabetes, emphasizes the importance of such redox mechanism-based and targeted approaches.
T2  - Mechanisms of Ageing and Development
T1  - The role of nitric oxide in diabetic skin (patho)physiology
VL  - 172
DO  - 10.1016/j.mad.2017.08.018
SP  - 21
EP  - 29
ER  - 

@article{
author = "Stančić, Ana and Janković, Aleksandra and Korać, Aleksandra and Buzadžić, Biljana and Otašević, Vesna and Korać, Bato",
year = "2018",
abstract = "The role of nitric oxide (NO) in cutaneous physiology/pathology became a growing research field since the discovery that almost all types of skin cells can synthetize this redox signaling molecule about 20 years ago. Now, it is evident that NO is an important player in skin physiological processes and in responses of cutaneous cells to external insults, while the impaired NO signaling has an important consequence in skin pathology. Skin disorders are common complications in diabetic conditions. Various metabolic/biochemical and immunological dysregulations in diabetic skin are tightly coupled with the disturbances in the redox state, primarily the ratio between NO and superoxide (O(cyrillic) 2 - ). This review describes possible therapeutic significance of different redox state modulators in the treatment of diabetic skin disorders. The focus is on those modulators that tightly control NO/O(cyrillic) 2 - ratio through the complex mechanisms affecting endogenous NO and O(cyrillic) 2 - producing and removing systems. The fact that classic antioxidants failed to show significant benefits in diabetes, emphasizes the importance of such redox mechanism-based and targeted approaches.",
journal = "Mechanisms of Ageing and Development",
title = "The role of nitric oxide in diabetic skin (patho)physiology",
volume = "172",
doi = "10.1016/j.mad.2017.08.018",
pages = "21-29"
}

Stančić, A., Janković, A., Korać, A., Buzadžić, B., Otašević, V.,& Korać, B.. (2018). The role of nitric oxide in diabetic skin (patho)physiology. in Mechanisms of Ageing and Development, 172, 21-29.
https://doi.org/10.1016/j.mad.2017.08.018

Stančić A, Janković A, Korać A, Buzadžić B, Otašević V, Korać B. The role of nitric oxide in diabetic skin (patho)physiology. in Mechanisms of Ageing and Development. 2018;172:21-29.
doi:10.1016/j.mad.2017.08.018 .

Stančić, Ana, Janković, Aleksandra, Korać, Aleksandra, Buzadžić, Biljana, Otašević, Vesna, Korać, Bato, "The role of nitric oxide in diabetic skin (patho)physiology" in Mechanisms of Ageing and Development, 172 (2018):21-29,
https://doi.org/10.1016/j.mad.2017.08.018 . .

TY  - JOUR
AU  - Stančić, Ana
AU  - Janković, Aleksandra
AU  - Korać, Aleksandra
AU  - Ćirović, Duško
AU  - Otašević, Vesna
AU  - Storey, Kenneth B.
AU  - Korać, Bato
PY  - 2018
UR  - http://linkinghub.elsevier.com/retrieve/pii/S1096495918300198
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3011
AB  - In the present study we hypothesized that myocardial adaptive phenotype in mammalian hibernation involves rearrangement of mitochondria bioenergetic pathways providing protective pattern in states of reduced metabolism and low temperature. European ground squirrels (Spermophilus citellus) were exposed to low temperature (4 ± 1 °C) and then divided into two groups: (1) animals that fell into torpor (hibernating group) and (2) animals that stayed active and euthermic for 1, 3, 7, 12, or 21 days (cold-exposed group). Protein levels of selected components of the electron transport chain and ATP synthase in the heart increased after prolonged cold acclimation (mainly from day 7-21 of cold exposure) and during hibernation. Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) was also upregulated under both cold exposure and hibernating conditions. The phosphorylation state (Thr172) of 5'-AMP-activated protein kinase α increased early in cold exposure (at day 1 and 3) along with increased protein levels of phosphofructokinase and pyruvate dehydrogenase, whereas hypoxia inducible factor 1α protein levels showed no changes in response to cold exposure or hibernation. Hibernation also resulted in protein upregulation of three antioxidant defense enzymes (manganese and copper/zinc superoxide dismutases and glutathione peroxidase) and thioredoxin in the heart. Cold-exposed and hibernation-related phenotypes of the heart are characterized by improved molecular basis for mitochondrial energy-producing and antioxidant capacities that are achieved in a controlled manner. The recapitulation of such adaptive mechanisms found in hibernators could have broad application for myocardial protection from ishemia/reperfusion to improve hypothermic survival and cold preservation of hearts from non-hibernating species, including humans.
T2  - Comparative Biochemistry and Physiology. B: Biochemistry and Molecular Biology
T1  - A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection.
VL  - 219-220
DO  - 10.1016/j.cbpb.2018.02.004
SP  - 1
EP  - 9
ER  - 

@article{
author = "Stančić, Ana and Janković, Aleksandra and Korać, Aleksandra and Ćirović, Duško and Otašević, Vesna and Storey, Kenneth B. and Korać, Bato",
year = "2018",
abstract = "In the present study we hypothesized that myocardial adaptive phenotype in mammalian hibernation involves rearrangement of mitochondria bioenergetic pathways providing protective pattern in states of reduced metabolism and low temperature. European ground squirrels (Spermophilus citellus) were exposed to low temperature (4 ± 1 °C) and then divided into two groups: (1) animals that fell into torpor (hibernating group) and (2) animals that stayed active and euthermic for 1, 3, 7, 12, or 21 days (cold-exposed group). Protein levels of selected components of the electron transport chain and ATP synthase in the heart increased after prolonged cold acclimation (mainly from day 7-21 of cold exposure) and during hibernation. Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) was also upregulated under both cold exposure and hibernating conditions. The phosphorylation state (Thr172) of 5'-AMP-activated protein kinase α increased early in cold exposure (at day 1 and 3) along with increased protein levels of phosphofructokinase and pyruvate dehydrogenase, whereas hypoxia inducible factor 1α protein levels showed no changes in response to cold exposure or hibernation. Hibernation also resulted in protein upregulation of three antioxidant defense enzymes (manganese and copper/zinc superoxide dismutases and glutathione peroxidase) and thioredoxin in the heart. Cold-exposed and hibernation-related phenotypes of the heart are characterized by improved molecular basis for mitochondrial energy-producing and antioxidant capacities that are achieved in a controlled manner. The recapitulation of such adaptive mechanisms found in hibernators could have broad application for myocardial protection from ishemia/reperfusion to improve hypothermic survival and cold preservation of hearts from non-hibernating species, including humans.",
journal = "Comparative Biochemistry and Physiology. B: Biochemistry and Molecular Biology",
title = "A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection.",
volume = "219-220",
doi = "10.1016/j.cbpb.2018.02.004",
pages = "1-9"
}

Stančić, A., Janković, A., Korać, A., Ćirović, D., Otašević, V., Storey, K. B.,& Korać, B.. (2018). A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection.. in Comparative Biochemistry and Physiology. B: Biochemistry and Molecular Biology, 219-220, 1-9.
https://doi.org/10.1016/j.cbpb.2018.02.004

Stančić A, Janković A, Korać A, Ćirović D, Otašević V, Storey KB, Korać B. A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection.. in Comparative Biochemistry and Physiology. B: Biochemistry and Molecular Biology. 2018;219-220:1-9.
doi:10.1016/j.cbpb.2018.02.004 .

Stančić, Ana, Janković, Aleksandra, Korać, Aleksandra, Ćirović, Duško, Otašević, Vesna, Storey, Kenneth B., Korać, Bato, "A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection." in Comparative Biochemistry and Physiology. B: Biochemistry and Molecular Biology, 219-220 (2018):1-9,
https://doi.org/10.1016/j.cbpb.2018.02.004 . .

TY  - JOUR
AU  - Kalezić, Anđelika
AU  - Macanović, Biljana
AU  - Garalejić, Eliana
AU  - Korać, Aleksandra
AU  - Otašević, Vesna
AU  - Korać, Bato
PY  - 2018
UR  - https://www.sciencedirect.com/science/article/pii/S0009279718304654?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3109
AB  - Nitric oxide (NO) is a signaling molecule responsible for initiation of molecular events that influence sperm functionality in a concentration-dependent manner. It is still not fully understood how seminal plasma NO contributes to sperm pathologies. The aim of this study was to elucidate whether and how NO is implicated in etiology of different sperm abnormalities. To this end we determine NO, nitrite and 3-nitrotyrosine (3-NT) content in seminal plasma of infertile men with specific pathologies (terato-, oligoterato- and oligoasthenoteratospermia) and relate it to infertile normospermic samples. To gain further understanding of NO metabolism in seminal plasma we determine protein expression of endothelial nitric oxide synthase (eNOS) and inducible nitric oxide synthase (iNOS). Here we show that NO, nitrite and 3-NT levels in seminal plasma of men with suboptimal semen parameters are significantly lower compared to normospermic men. An increase in protein expression of eNOS and no change in protein expression of iNOS is observed in men with sperm pathologies. Association of seminal plasma 3-NT level with functional sperm parameters is observed - positive correlation with sperm count, motility and morphology in normospermia, teratospermia and oligoteratospermia, as well as negative correlation with sperm morphology and motility in oligoasthenoteratospermia. Present study revealed that suboptimal seminal plasma NO content is found in all examined sperm pathologies. This result unequivocally shows the importance of NO for sperm function and involvement of suboptimal NO level in etiology of sperm abnormalities. Lower seminal plasma 3-NT level and its significant association with sperm parameters, found in pathologies, strongly indicates that protein nitration is important for spermatozoa function and that failure to establish this post-translational protein modification might be involved in etiology of sperm abnormalities. According to our results, NO measurement can discriminate infertile men with sperm pathologies from infertile normospermic men but is not indicative of a specific type of sperm pathology.
T2  - Chemico-Biological Interactions
T1  - Level of NO/nitrite and 3-nitrotyrosine in seminal plasma of infertile men: Correlation with sperm number, motility and morphology.
VL  - 291
DO  - 10.1016/j.cbi.2018.07.002
SP  - 264
EP  - 270
ER  - 

@article{
author = "Kalezić, Anđelika and Macanović, Biljana and Garalejić, Eliana and Korać, Aleksandra and Otašević, Vesna and Korać, Bato",
year = "2018",
abstract = "Nitric oxide (NO) is a signaling molecule responsible for initiation of molecular events that influence sperm functionality in a concentration-dependent manner. It is still not fully understood how seminal plasma NO contributes to sperm pathologies. The aim of this study was to elucidate whether and how NO is implicated in etiology of different sperm abnormalities. To this end we determine NO, nitrite and 3-nitrotyrosine (3-NT) content in seminal plasma of infertile men with specific pathologies (terato-, oligoterato- and oligoasthenoteratospermia) and relate it to infertile normospermic samples. To gain further understanding of NO metabolism in seminal plasma we determine protein expression of endothelial nitric oxide synthase (eNOS) and inducible nitric oxide synthase (iNOS). Here we show that NO, nitrite and 3-NT levels in seminal plasma of men with suboptimal semen parameters are significantly lower compared to normospermic men. An increase in protein expression of eNOS and no change in protein expression of iNOS is observed in men with sperm pathologies. Association of seminal plasma 3-NT level with functional sperm parameters is observed - positive correlation with sperm count, motility and morphology in normospermia, teratospermia and oligoteratospermia, as well as negative correlation with sperm morphology and motility in oligoasthenoteratospermia. Present study revealed that suboptimal seminal plasma NO content is found in all examined sperm pathologies. This result unequivocally shows the importance of NO for sperm function and involvement of suboptimal NO level in etiology of sperm abnormalities. Lower seminal plasma 3-NT level and its significant association with sperm parameters, found in pathologies, strongly indicates that protein nitration is important for spermatozoa function and that failure to establish this post-translational protein modification might be involved in etiology of sperm abnormalities. According to our results, NO measurement can discriminate infertile men with sperm pathologies from infertile normospermic men but is not indicative of a specific type of sperm pathology.",
journal = "Chemico-Biological Interactions",
title = "Level of NO/nitrite and 3-nitrotyrosine in seminal plasma of infertile men: Correlation with sperm number, motility and morphology.",
volume = "291",
doi = "10.1016/j.cbi.2018.07.002",
pages = "264-270"
}

Kalezić, A., Macanović, B., Garalejić, E., Korać, A., Otašević, V.,& Korać, B.. (2018). Level of NO/nitrite and 3-nitrotyrosine in seminal plasma of infertile men: Correlation with sperm number, motility and morphology.. in Chemico-Biological Interactions, 291, 264-270.
https://doi.org/10.1016/j.cbi.2018.07.002

Kalezić A, Macanović B, Garalejić E, Korać A, Otašević V, Korać B. Level of NO/nitrite and 3-nitrotyrosine in seminal plasma of infertile men: Correlation with sperm number, motility and morphology.. in Chemico-Biological Interactions. 2018;291:264-270.
doi:10.1016/j.cbi.2018.07.002 .

Kalezić, Anđelika, Macanović, Biljana, Garalejić, Eliana, Korać, Aleksandra, Otašević, Vesna, Korać, Bato, "Level of NO/nitrite and 3-nitrotyrosine in seminal plasma of infertile men: Correlation with sperm number, motility and morphology." in Chemico-Biological Interactions, 291 (2018):264-270,
https://doi.org/10.1016/j.cbi.2018.07.002 . .

TY  - JOUR
AU  - Otašević, Vesna
AU  - Korać, Aleksandra
AU  - Stančić, Ana
AU  - Janković, Aleksandra
AU  - Korać, Bato
PY  - 2018
UR  - http://hrana-ishrana.org/wp-content/uploads/2019/01/Hrana-i-ishrana-59-br-2.pdf
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3320
AB  - Infertility is one of the most serious medical issues that is dramatically rising worldwide. Extensive research dedicated to this problem clearly shows that infertility is a disease of modern society and that a nutrition has a great infl uence on the development of sterility. Thus, the impact of specifi c nutritional factors, i.e. diet pattern on both male and female fertility is included in this review. It is encouraging that modifi cation of nutritional habits can help couples to conceive spontaneously, or increase their chances of conception with in vitro fertilization (IVF) treatment.
T2  - Hrana i Ishrana
T1  - Impact of nutrition on human fertility
IS  - 2
VL  - 59
SP  - 53
EP  - 58
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_3320
ER  - 

@article{
author = "Otašević, Vesna and Korać, Aleksandra and Stančić, Ana and Janković, Aleksandra and Korać, Bato",
year = "2018",
abstract = "Infertility is one of the most serious medical issues that is dramatically rising worldwide. Extensive research dedicated to this problem clearly shows that infertility is a disease of modern society and that a nutrition has a great infl uence on the development of sterility. Thus, the impact of specifi c nutritional factors, i.e. diet pattern on both male and female fertility is included in this review. It is encouraging that modifi cation of nutritional habits can help couples to conceive spontaneously, or increase their chances of conception with in vitro fertilization (IVF) treatment.",
journal = "Hrana i Ishrana",
title = "Impact of nutrition on human fertility",
number = "2",
volume = "59",
pages = "53-58",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_3320"
}

Otašević, V., Korać, A., Stančić, A., Janković, A.,& Korać, B.. (2018). Impact of nutrition on human fertility. in Hrana i Ishrana, 59(2), 53-58.
https://hdl.handle.net/21.15107/rcub_ibiss_3320

Otašević V, Korać A, Stančić A, Janković A, Korać B. Impact of nutrition on human fertility. in Hrana i Ishrana. 2018;59(2):53-58.
https://hdl.handle.net/21.15107/rcub_ibiss_3320 .

Otašević, Vesna, Korać, Aleksandra, Stančić, Ana, Janković, Aleksandra, Korać, Bato, "Impact of nutrition on human fertility" in Hrana i Ishrana, 59, no. 2 (2018):53-58,
https://hdl.handle.net/21.15107/rcub_ibiss_3320 .

TY  - JOUR
AU  - Stančić, Ana
AU  - Filipović, Miloš
AU  - Ivanović-Burmazović, Ivana
AU  - Mašović, Sava
AU  - Janković, Aleksandra
AU  - Otašević, Vesna
AU  - Korać, Aleksandra
AU  - Buzadžić, Biljana
AU  - Korać, Bato
PY  - 2017
UR  - http://linkinghub.elsevier.com/retrieve/pii/S0009279717300030
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2766
AB  - Considering the vital role of skeletal muscle in control of whole-body metabolism and the severity of long-term diabetic complications, we aimed to reveal the molecular pattern of early diabetes-related skeletal muscle phenotype in terms of energy metabolism, focusing on regulatory mechanisms, and the possibility to improve it using two redox modulators, L-arginine and superoxide dismutase (SOD) mimic. Alloxan-induced diabetic rats (120 mg/kg) were treated with L-arginine or the highly specific SOD mimic, M40403, for 7 days. As appropriate controls, non-diabetic rats received the same treatments. We found that L-arginine and M40403 restored diabetes-induced impairment of phospho-5′-AMP-activated protein kinase α (AMPKα) signaling by upregulating AMPKα protein itself and its downstream effectors, peroxisome proliferator-activated receptor-γ coactivator-1α and nuclear respiratory factor 1. Also, there was a restitution of the protein levels of oxidative phosphorylation components (complex I, complex II and complex IV) and mitofusin 2. Furthermore, L-arginine and M40403 induced translocation of glucose transporter 4 to the membrane and upregulation of protein of phosphofructokinase and acyl coenzyme A dehydrogenase, diminishing negative diabetic effects on limiting factors of glucose and lipid metabolism. Both treatments abolished diabetes-induced downregulation of sarcoplasmic reticulum calcium-ATPase proteins (SERCA 1 and 2). Similar effects of L-arginine and SOD mimic treatments suggest that disturbances in the superoxide/nitric oxide ratio may be responsible for skeletal muscle mitochondrial and metabolic impairment in early diabetes. Our results provide evidence that L-arginine and SOD mimics have potential in preventing and treating metabolic disturbances accompanying this widespread metabolic disease.
T2  - Chemico-Biological Interactions
T1  - Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l -arginine and SOD mimic
VL  - 272
DO  - 10.1016/j.cbi.2017.05.003
SP  - 188
EP  - 196
ER  - 

@article{
author = "Stančić, Ana and Filipović, Miloš and Ivanović-Burmazović, Ivana and Mašović, Sava and Janković, Aleksandra and Otašević, Vesna and Korać, Aleksandra and Buzadžić, Biljana and Korać, Bato",
year = "2017",
abstract = "Considering the vital role of skeletal muscle in control of whole-body metabolism and the severity of long-term diabetic complications, we aimed to reveal the molecular pattern of early diabetes-related skeletal muscle phenotype in terms of energy metabolism, focusing on regulatory mechanisms, and the possibility to improve it using two redox modulators, L-arginine and superoxide dismutase (SOD) mimic. Alloxan-induced diabetic rats (120 mg/kg) were treated with L-arginine or the highly specific SOD mimic, M40403, for 7 days. As appropriate controls, non-diabetic rats received the same treatments. We found that L-arginine and M40403 restored diabetes-induced impairment of phospho-5′-AMP-activated protein kinase α (AMPKα) signaling by upregulating AMPKα protein itself and its downstream effectors, peroxisome proliferator-activated receptor-γ coactivator-1α and nuclear respiratory factor 1. Also, there was a restitution of the protein levels of oxidative phosphorylation components (complex I, complex II and complex IV) and mitofusin 2. Furthermore, L-arginine and M40403 induced translocation of glucose transporter 4 to the membrane and upregulation of protein of phosphofructokinase and acyl coenzyme A dehydrogenase, diminishing negative diabetic effects on limiting factors of glucose and lipid metabolism. Both treatments abolished diabetes-induced downregulation of sarcoplasmic reticulum calcium-ATPase proteins (SERCA 1 and 2). Similar effects of L-arginine and SOD mimic treatments suggest that disturbances in the superoxide/nitric oxide ratio may be responsible for skeletal muscle mitochondrial and metabolic impairment in early diabetes. Our results provide evidence that L-arginine and SOD mimics have potential in preventing and treating metabolic disturbances accompanying this widespread metabolic disease.",
journal = "Chemico-Biological Interactions",
title = "Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l -arginine and SOD mimic",
volume = "272",
doi = "10.1016/j.cbi.2017.05.003",
pages = "188-196"
}

Stančić, A., Filipović, M., Ivanović-Burmazović, I., Mašović, S., Janković, A., Otašević, V., Korać, A., Buzadžić, B.,& Korać, B.. (2017). Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l -arginine and SOD mimic. in Chemico-Biological Interactions, 272, 188-196.
https://doi.org/10.1016/j.cbi.2017.05.003

Stančić A, Filipović M, Ivanović-Burmazović I, Mašović S, Janković A, Otašević V, Korać A, Buzadžić B, Korać B. Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l -arginine and SOD mimic. in Chemico-Biological Interactions. 2017;272:188-196.
doi:10.1016/j.cbi.2017.05.003 .

Stančić, Ana, Filipović, Miloš, Ivanović-Burmazović, Ivana, Mašović, Sava, Janković, Aleksandra, Otašević, Vesna, Korać, Aleksandra, Buzadžić, Biljana, Korać, Bato, "Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l -arginine and SOD mimic" in Chemico-Biological Interactions, 272 (2017):188-196,
https://doi.org/10.1016/j.cbi.2017.05.003 . .

TY  - JOUR
AU  - Otašević, Vesna
AU  - Šurlan, Lela
AU  - Vučetić, Milica
AU  - Tulić, Ivan
AU  - Buzadžić, Biljana
AU  - Stančić, Ana
AU  - Janković, Aleksandra
AU  - Veličković, Ksenija
AU  - Golić, Igor
AU  - Markelić, Milica
AU  - Korać, Aleksandra
AU  - Korać, Bato
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6213
AB  - Developmental dysfunction in embryos, such as a lethal level of fragmentation, is assumed to be mitochondrial in origin. This study investigated the molecular basis of mitochondrial impairment in embryo fragmentation. Transcription patterns of factors that determine mitochondrial functionality: (i) components of the oxidative phosphorylation (OXPHOS) - complex I, cytochrome b, complex IV and ATP synthase; (ii) mitochondrial membrane potential (MMP); (iii) mitochondrial DNA (mtDNA) content and (iv) proteins involved in mitochondrial dynamics, mitofusin 1 (Mfn1) and dynamin related protein 1 (Drp1) were examined in six-cells Day 3 non-fragmented (control), low-fragmented (LF) and high-fragmented (HF) human embryos. Gene expression of mitochondria-encoded components of complex I and IV, cytochrome b and mtDNA were increased in HF embryos compared with control and LF embryos. In LF embryos, expression of these molecules was decreased compared with control and HF embryos. Both classes of fragmented embryos had decreased MMP compared with control. LF embryos had increased gene expression of Mfn1 accompanied by decreased expression of Drp1, while HF embryos had decreased Mfn1 expression but increased Drp1 expression. The study revealed that each improper transcriptional (in)activation of mitochondria-encoded components of the OXPHOS during early in vitro embryo development is associated with a decrease in MMP and with embryo fragmentation. The results also showed the importance of mitochondrial dynamics in fragmentation, at least in the extent of this process.
PB  - CSIRO Publishing
T2  - Reproduction, Fertility and Development
T1  - Expression patterns of mitochondrial OXPHOS components, mitofusin 1 and dynamin-related protein 1 are associated with human embryo fragmentation
IS  - 3
VL  - 28
DO  - 10.1071/RD13415
SP  - 319
EP  - 327
ER  - 

@article{
author = "Otašević, Vesna and Šurlan, Lela and Vučetić, Milica and Tulić, Ivan and Buzadžić, Biljana and Stančić, Ana and Janković, Aleksandra and Veličković, Ksenija and Golić, Igor and Markelić, Milica and Korać, Aleksandra and Korać, Bato",
year = "2016",
abstract = "Developmental dysfunction in embryos, such as a lethal level of fragmentation, is assumed to be mitochondrial in origin. This study investigated the molecular basis of mitochondrial impairment in embryo fragmentation. Transcription patterns of factors that determine mitochondrial functionality: (i) components of the oxidative phosphorylation (OXPHOS) - complex I, cytochrome b, complex IV and ATP synthase; (ii) mitochondrial membrane potential (MMP); (iii) mitochondrial DNA (mtDNA) content and (iv) proteins involved in mitochondrial dynamics, mitofusin 1 (Mfn1) and dynamin related protein 1 (Drp1) were examined in six-cells Day 3 non-fragmented (control), low-fragmented (LF) and high-fragmented (HF) human embryos. Gene expression of mitochondria-encoded components of complex I and IV, cytochrome b and mtDNA were increased in HF embryos compared with control and LF embryos. In LF embryos, expression of these molecules was decreased compared with control and HF embryos. Both classes of fragmented embryos had decreased MMP compared with control. LF embryos had increased gene expression of Mfn1 accompanied by decreased expression of Drp1, while HF embryos had decreased Mfn1 expression but increased Drp1 expression. The study revealed that each improper transcriptional (in)activation of mitochondria-encoded components of the OXPHOS during early in vitro embryo development is associated with a decrease in MMP and with embryo fragmentation. The results also showed the importance of mitochondrial dynamics in fragmentation, at least in the extent of this process.",
publisher = "CSIRO Publishing",
journal = "Reproduction, Fertility and Development",
title = "Expression patterns of mitochondrial OXPHOS components, mitofusin 1 and dynamin-related protein 1 are associated with human embryo fragmentation",
number = "3",
volume = "28",
doi = "10.1071/RD13415",
pages = "319-327"
}

Otašević, V., Šurlan, L., Vučetić, M., Tulić, I., Buzadžić, B., Stančić, A., Janković, A., Veličković, K., Golić, I., Markelić, M., Korać, A.,& Korać, B.. (2016). Expression patterns of mitochondrial OXPHOS components, mitofusin 1 and dynamin-related protein 1 are associated with human embryo fragmentation. in Reproduction, Fertility and Development
CSIRO Publishing., 28(3), 319-327.
https://doi.org/10.1071/RD13415

Otašević V, Šurlan L, Vučetić M, Tulić I, Buzadžić B, Stančić A, Janković A, Veličković K, Golić I, Markelić M, Korać A, Korać B. Expression patterns of mitochondrial OXPHOS components, mitofusin 1 and dynamin-related protein 1 are associated with human embryo fragmentation. in Reproduction, Fertility and Development. 2016;28(3):319-327.
doi:10.1071/RD13415 .

Otašević, Vesna, Šurlan, Lela, Vučetić, Milica, Tulić, Ivan, Buzadžić, Biljana, Stančić, Ana, Janković, Aleksandra, Veličković, Ksenija, Golić, Igor, Markelić, Milica, Korać, Aleksandra, Korać, Bato, "Expression patterns of mitochondrial OXPHOS components, mitofusin 1 and dynamin-related protein 1 are associated with human embryo fragmentation" in Reproduction, Fertility and Development, 28, no. 3 (2016):319-327,
https://doi.org/10.1071/RD13415 . .

TY  - JOUR
AU  - Macanović, Biljana
AU  - Vučetić, Milica
AU  - Janković, Aleksandra
AU  - Stančić, Ana
AU  - Buzadžić, Biljana J.
AU  - Garalejić, Eliana
AU  - Korać, Aleksandra
AU  - Korać, Bato
AU  - Otašević, Vesna
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2090
AB  - Background. Semen analysis is the cornerstone in the evaluation of male
   (in) fertility. However, there are men with normal semen tests but with
   impaired fertilizing ability, as well as fertile men with poor sperm
   characteristics. Thus, there is rising interest to find novel parameters
   that will help to predict and define the functional capacity of
   spermatozoa. Methods. We examined whether there is a correlation between
   semen parameters (count, progressive motility, and morphology) and
   protein expression/activity of antioxidative defense enzymes in seminal
   plasma from 10 normospermic subjects. Results. Sperm progressive
   motility was in positive correlation with seminal plasma protein
   expression of both superoxide dismutase (SOD) isoforms (MnSOD and
   CuZnSOD) and catalase. Also, positive correlation was observed between
   sperm count and MnSOD protein expression, as well as between sperm
   morphology and protein expression of catalase in seminal plasma. In
   contrast, protein expression of glutathione peroxidase was not in
   correlation with any sperm parameter, while its activity negatively
   correlated with sperm morphology and motility. Conclusions. These data
   suggest that evaluation of protein expression of antioxidative defense
   enzymes in seminal plasma might be of importance in the evaluation of
   male fertility status and that could be used as an additional biomarker
   along with classic semen analysis in assessment of semen quality.
T2  - Disease Markers
T1  - Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study
IS  - 436236
DO  - 10.1155/2015/436236
ER  - 

@article{
author = "Macanović, Biljana and Vučetić, Milica and Janković, Aleksandra and Stančić, Ana and Buzadžić, Biljana J. and Garalejić, Eliana and Korać, Aleksandra and Korać, Bato and Otašević, Vesna",
year = "2015",
abstract = "Background. Semen analysis is the cornerstone in the evaluation of male
   (in) fertility. However, there are men with normal semen tests but with
   impaired fertilizing ability, as well as fertile men with poor sperm
   characteristics. Thus, there is rising interest to find novel parameters
   that will help to predict and define the functional capacity of
   spermatozoa. Methods. We examined whether there is a correlation between
   semen parameters (count, progressive motility, and morphology) and
   protein expression/activity of antioxidative defense enzymes in seminal
   plasma from 10 normospermic subjects. Results. Sperm progressive
   motility was in positive correlation with seminal plasma protein
   expression of both superoxide dismutase (SOD) isoforms (MnSOD and
   CuZnSOD) and catalase. Also, positive correlation was observed between
   sperm count and MnSOD protein expression, as well as between sperm
   morphology and protein expression of catalase in seminal plasma. In
   contrast, protein expression of glutathione peroxidase was not in
   correlation with any sperm parameter, while its activity negatively
   correlated with sperm morphology and motility. Conclusions. These data
   suggest that evaluation of protein expression of antioxidative defense
   enzymes in seminal plasma might be of importance in the evaluation of
   male fertility status and that could be used as an additional biomarker
   along with classic semen analysis in assessment of semen quality.",
journal = "Disease Markers",
title = "Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study",
number = "436236",
doi = "10.1155/2015/436236"
}

Macanović, B., Vučetić, M., Janković, A., Stančić, A., Buzadžić, B. J., Garalejić, E., Korać, A., Korać, B.,& Otašević, V.. (2015). Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study. in Disease Markers(436236).
https://doi.org/10.1155/2015/436236

Macanović B, Vučetić M, Janković A, Stančić A, Buzadžić BJ, Garalejić E, Korać A, Korać B, Otašević V. Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study. in Disease Markers. 2015;(436236).
doi:10.1155/2015/436236 .

Macanović, Biljana, Vučetić, Milica, Janković, Aleksandra, Stančić, Ana, Buzadžić, Biljana J., Garalejić, Eliana, Korać, Aleksandra, Korać, Bato, Otašević, Vesna, "Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study" in Disease Markers, no. 436236 (2015),
https://doi.org/10.1155/2015/436236 . .

TY  - JOUR
AU  - Veličković, Ksenija
AU  - Čvoro, Aleksandra
AU  - Srdić, Biljana
AU  - Stokić, Edita
AU  - Markelić, Milica
AU  - Golić, Igor
AU  - Otašević, Vesna
AU  - Stančić, Ana
AU  - Janković, Aleksandra
AU  - Vučetić, Milica
AU  - Buzadžić, Biljana J.
AU  - Korać, Bato
AU  - Korać, Aleksandra
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2294
AB  - Context: Brown adipose tissue (BAT) has the unique ability of generating
   heat due to the expression of mitochondrial uncoupling protein 1 (UCP1).
   A recent discovery regarding functional BAT in adult humans has
   increased interest in the molecular pathways of BAT development and
   functionality. An important role for estrogen in white adipose tissue
   was shown, but the possible role of estrogen in human fetal BAT (fBAT)
   is unclear.
   Objective: The objective of this study was to determine whether human
   fBAT expresses estrogen receptor alpha (ER alpha) and ER beta. In
   addition, we examined their localization as well as their correlation
   with crucial proteins involved in BAT differentiation, proliferation,
   mitochondriogenesis and thermogenesis including peroxisome
   proliferator-activated receptor gamma (PPAR gamma), proliferating cell
   nuclear antigen (PCNA), PPAR gamma-coactivator-1 alpha (PGC-1 alpha),
   and UCP1.
   Design: The fBAT was obtained from 4 human male fetuses aged 15, 17, 20,
   and 23 weeks gestation. ER alpha and ER beta expression was assessed
   using Western blotting, immunohistochemistry, and immunocytochemistry.
   Possible correlations with PPAR gamma, PCNA, PGC-1 alpha, and UCP1 were
   examined by double immunofluorescence.
   Results: Both ER alpha and ER beta were expressed in human fBAT, with ER
   alpha being dominant. Unlike ER beta, which was present only in mature
   brown adipocytes, we detected ER alpha in mature adipocytes,
   preadipocytes, mesenchymal and endothelial cells. In addition, double
   immunofluorescence supported the notion that differentiation in fBAT
   probably involves ER alpha. Immunocytochemical analysis revealed
   mitochondrial localization of both receptors.
   Conclusion: The expression of both ER alpha and ER beta in human fBAT
   suggests a role for estrogen in its development, primarily via ER alpha.
   In addition, our results indicate that fBAT mitochondria could be
   targeted by estrogens and pointed out the possible role of both ERs in
   mitochondriogenesis.
T2  - Journal of Clinical Endocrinology & Metabolism
T1  - Expression and Subcellular Localization of Estrogen Receptors alpha and
 beta in Human Fetal Brown Adipose Tissue
IS  - 1
VL  - 99
DO  - 10.1210/jc.2013-2017
SP  - 151
EP  - 159
ER  - 

@article{
author = "Veličković, Ksenija and Čvoro, Aleksandra and Srdić, Biljana and Stokić, Edita and Markelić, Milica and Golić, Igor and Otašević, Vesna and Stančić, Ana and Janković, Aleksandra and Vučetić, Milica and Buzadžić, Biljana J. and Korać, Bato and Korać, Aleksandra",
year = "2014",
abstract = "Context: Brown adipose tissue (BAT) has the unique ability of generating
   heat due to the expression of mitochondrial uncoupling protein 1 (UCP1).
   A recent discovery regarding functional BAT in adult humans has
   increased interest in the molecular pathways of BAT development and
   functionality. An important role for estrogen in white adipose tissue
   was shown, but the possible role of estrogen in human fetal BAT (fBAT)
   is unclear.
   Objective: The objective of this study was to determine whether human
   fBAT expresses estrogen receptor alpha (ER alpha) and ER beta. In
   addition, we examined their localization as well as their correlation
   with crucial proteins involved in BAT differentiation, proliferation,
   mitochondriogenesis and thermogenesis including peroxisome
   proliferator-activated receptor gamma (PPAR gamma), proliferating cell
   nuclear antigen (PCNA), PPAR gamma-coactivator-1 alpha (PGC-1 alpha),
   and UCP1.
   Design: The fBAT was obtained from 4 human male fetuses aged 15, 17, 20,
   and 23 weeks gestation. ER alpha and ER beta expression was assessed
   using Western blotting, immunohistochemistry, and immunocytochemistry.
   Possible correlations with PPAR gamma, PCNA, PGC-1 alpha, and UCP1 were
   examined by double immunofluorescence.
   Results: Both ER alpha and ER beta were expressed in human fBAT, with ER
   alpha being dominant. Unlike ER beta, which was present only in mature
   brown adipocytes, we detected ER alpha in mature adipocytes,
   preadipocytes, mesenchymal and endothelial cells. In addition, double
   immunofluorescence supported the notion that differentiation in fBAT
   probably involves ER alpha. Immunocytochemical analysis revealed
   mitochondrial localization of both receptors.
   Conclusion: The expression of both ER alpha and ER beta in human fBAT
   suggests a role for estrogen in its development, primarily via ER alpha.
   In addition, our results indicate that fBAT mitochondria could be
   targeted by estrogens and pointed out the possible role of both ERs in
   mitochondriogenesis.",
journal = "Journal of Clinical Endocrinology & Metabolism",
title = "Expression and Subcellular Localization of Estrogen Receptors alpha and
 beta in Human Fetal Brown Adipose Tissue",
number = "1",
volume = "99",
doi = "10.1210/jc.2013-2017",
pages = "151-159"
}

Veličković, K., Čvoro, A., Srdić, B., Stokić, E., Markelić, M., Golić, I., Otašević, V., Stančić, A., Janković, A., Vučetić, M., Buzadžić, B. J., Korać, B.,& Korać, A.. (2014). Expression and Subcellular Localization of Estrogen Receptors alpha and
 beta in Human Fetal Brown Adipose Tissue. in Journal of Clinical Endocrinology & Metabolism, 99(1), 151-159.
https://doi.org/10.1210/jc.2013-2017

Veličković K, Čvoro A, Srdić B, Stokić E, Markelić M, Golić I, Otašević V, Stančić A, Janković A, Vučetić M, Buzadžić BJ, Korać B, Korać A. Expression and Subcellular Localization of Estrogen Receptors alpha and
 beta in Human Fetal Brown Adipose Tissue. in Journal of Clinical Endocrinology & Metabolism. 2014;99(1):151-159.
doi:10.1210/jc.2013-2017 .

Veličković, Ksenija, Čvoro, Aleksandra, Srdić, Biljana, Stokić, Edita, Markelić, Milica, Golić, Igor, Otašević, Vesna, Stančić, Ana, Janković, Aleksandra, Vučetić, Milica, Buzadžić, Biljana J., Korać, Bato, Korać, Aleksandra, "Expression and Subcellular Localization of Estrogen Receptors alpha and
 beta in Human Fetal Brown Adipose Tissue" in Journal of Clinical Endocrinology & Metabolism, 99, no. 1 (2014):151-159,
https://doi.org/10.1210/jc.2013-2017 . .