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The effect of O-GlcNAc glycosylation of rat liver nucleoproteins on their acute phase-dependent binding ability to the hormone responsive element of the haptoglobin gene

Grigorov, Ilijana; Cvetković, Ivana; Milosavljević, Tomislav; Uskoković, Aleksandra; Bogojević, Desanka; Ivanović Matić, Svetlana; Poznanović, Goran; Petrović, Miodrag

(Bratislava: Aepress, 2004)

TY  - JOUR
AU  - Grigorov, Ilijana
AU  - Cvetković, Ivana
AU  - Milosavljević, Tomislav
AU  - Uskoković, Aleksandra
AU  - Bogojević, Desanka
AU  - Ivanović Matić, Svetlana
AU  - Poznanović, Goran
AU  - Petrović, Miodrag
PY  - 2004
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6543
AB  - We examined whether the transcriptional activation of the rat haptoglobin (Hp) gene during the acute phase (AP) response reflects the O-linked N-acetylglucosamine (O-GlcNAc) status of liver nucleoproteins (NPs) and their binding for the hormone responsive element (HRE). After deglycosylation with N-acetylglucosaininidase of the O-GlcNAc glycoproteins obtained by WGA, affinity chromatography and South-Western analysis, it was observed that only increased HRE binding ability of p64/p70 in control and p51 obtained from turpentine-treated rats can be directly attributed to the presence of O-GlcNAc residues. Therefore, expression of the rat Hp gene could be controlled by this modification of certain trans-acting NPs.
PB  - Bratislava: Aepress
T2  - General Physiology and Biophysics
T1  - The effect of O-GlcNAc glycosylation of rat liver nucleoproteins on their acute phase-dependent binding ability to the hormone responsive element of the haptoglobin gene
IS  - 3
VL  - 23
SP  - 367
EP  - 374
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6543
ER  - 
@article{
author = "Grigorov, Ilijana and Cvetković, Ivana and Milosavljević, Tomislav and Uskoković, Aleksandra and Bogojević, Desanka and Ivanović Matić, Svetlana and Poznanović, Goran and Petrović, Miodrag",
year = "2004",
abstract = "We examined whether the transcriptional activation of the rat haptoglobin (Hp) gene during the acute phase (AP) response reflects the O-linked N-acetylglucosamine (O-GlcNAc) status of liver nucleoproteins (NPs) and their binding for the hormone responsive element (HRE). After deglycosylation with N-acetylglucosaininidase of the O-GlcNAc glycoproteins obtained by WGA, affinity chromatography and South-Western analysis, it was observed that only increased HRE binding ability of p64/p70 in control and p51 obtained from turpentine-treated rats can be directly attributed to the presence of O-GlcNAc residues. Therefore, expression of the rat Hp gene could be controlled by this modification of certain trans-acting NPs.",
publisher = "Bratislava: Aepress",
journal = "General Physiology and Biophysics",
title = "The effect of O-GlcNAc glycosylation of rat liver nucleoproteins on their acute phase-dependent binding ability to the hormone responsive element of the haptoglobin gene",
number = "3",
volume = "23",
pages = "367-374",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6543"
}
Grigorov, I., Cvetković, I., Milosavljević, T., Uskoković, A., Bogojević, D., Ivanović Matić, S., Poznanović, G.,& Petrović, M.. (2004). The effect of O-GlcNAc glycosylation of rat liver nucleoproteins on their acute phase-dependent binding ability to the hormone responsive element of the haptoglobin gene. in General Physiology and Biophysics
Bratislava: Aepress., 23(3), 367-374.
https://hdl.handle.net/21.15107/rcub_ibiss_6543
Grigorov I, Cvetković I, Milosavljević T, Uskoković A, Bogojević D, Ivanović Matić S, Poznanović G, Petrović M. The effect of O-GlcNAc glycosylation of rat liver nucleoproteins on their acute phase-dependent binding ability to the hormone responsive element of the haptoglobin gene. in General Physiology and Biophysics. 2004;23(3):367-374.
https://hdl.handle.net/21.15107/rcub_ibiss_6543 .
Grigorov, Ilijana, Cvetković, Ivana, Milosavljević, Tomislav, Uskoković, Aleksandra, Bogojević, Desanka, Ivanović Matić, Svetlana, Poznanović, Goran, Petrović, Miodrag, "The effect of O-GlcNAc glycosylation of rat liver nucleoproteins on their acute phase-dependent binding ability to the hormone responsive element of the haptoglobin gene" in General Physiology and Biophysics, 23, no. 3 (2004):367-374,
https://hdl.handle.net/21.15107/rcub_ibiss_6543 .
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