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Responsiveness of thyroid C cells to steroid hormones
dc.creator | Sekulić, Milka I. | |
dc.creator | Lovren, Mirjana B. | |
dc.date.accessioned | 2017-11-23T11:15:37Z | |
dc.date.available | 2015-11-17T10:26:51Z | |
dc.date.issued | 2000 | sr |
dc.identifier.issn | 0354-3447 | sr |
dc.identifier.other | Rad_konverzija_3825 | sr |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/1830 | |
dc.description.abstract | The role of steroids in the regulation of thyroid C and mast cells function of rats and pigs were the object of our experimental examinations. The argyrophil properties, morphometric characteristics and subcellular organization of C and mast cells in rats of both sexes after neonatal estradiol-dipropionate treatment were studied. A special attention has been paid to the changes in the structure of thyroid C cells after a chronical treatment of aged (2-year-old) rats with estradiol-dipropionate or testosterone propionate. Besides, the structure and function of immunoreactive C cells of middle-aged female rats (14-month-old) chronically treated with estradiol-dipropionate, calcium or a combination of estradiol-dipropionate and calcium were observed. Serum levels of calcitonin, osteocalcin, parathormone and beta-estradiol were also measured using RLA method. It has been observed that neonatal estradiol-dipropionate treatment expresses a long-term stimulative effects on rat thyroid C cells, while chronic treatment of middle-aged rats with estradiol-dipropionate acts inhibitory on these cells. In addition, the argyrophil properties and ultrastructural characteristics of C cells of male pigs treated with estradiol--dipropionate and progesterone in combination or castrated on the first day of life and sacrificed 6 or 8 months later were investigated. A slower rate of specific protein synthesis and secretion of porcine C cells after sex steroids treatment was observed. | en |
dc.description.sponsorship | null | sr |
dc.language.iso | English | sr |
dc.rights | restrictedAccess | |
dc.source | Jugoslovenska Medicinska Biohemija-Yugoslav Medical Biochemistry | sr |
dc.title | Responsiveness of thyroid C cells to steroid hormones | en |
dc.type | review | |
dc.rights.license | ARR | |
dcterms.abstract | Ловрен, Мирјана Б.; Секулић, Милка И.; | |
dc.citation.issue | 3 | sr |
dc.citation.volume | 19 | sr |
dc.citation.epage | 160 | sr |
dc.type.version | publishedVersion | en |
dc.citation.rank | M23 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_ibiss_1830 |
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