dc.creator | Srdjenovic, Branislava U. | |
dc.creator | Slavic, Marija N. | |
dc.creator | Stankov, Karmen M. | |
dc.creator | Kladar, Nebojsa V. | |
dc.creator | Jovic, Danica S. | |
dc.creator | Seke, Mariana N. | |
dc.creator | Bogdanovic, Visnja V. | |
dc.date.accessioned | 2016-05-23T10:59:42Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 2217-7426 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/1929 | |
dc.description.abstract | Fullerenol (C-60(OH)(24)) nanoparticles (FNP) have a significant role in
biomedical research due to their numerous biological activities, some of
which have cytoprotective and anti-oxidative properties. The aim of this
study was to measure distribution of fullerenol nanoparticles and zeta
potential in cell medium RPMI 1640 with 10\% fetal bovine serum (FBS)
and to investigate the influence of FNP on Chinese hamster ovary cells
(CHO-K1) survival, as well as to determine the activity of three
antioxidative enzymes: superoxide-dismutase, glutathione-reductase and
glutathione-S-transferase in mitomycin C-treated cell line. Our
investigation implies that FNP, as a strong antioxidant, influences the
cellular redox state and enzyme activities and thus may reduce cell
proliferation, which confirms that FNP could be exploited for its use as
a cytoprotective agent. | en |
dc.description.sponsorship | Ministry of Education, Science and Technological Development of the
Republic of Serbia {[}III45005]; Provincial Secretariat for Science and
Technological Development of Vojvodina {[}114-451-2056/2011-01] | |
dc.language | English | |
dc.rights | restrictedAccess | |
dc.source | Hemijska Industrija | |
dc.subject | fullerenol | |
dc.subject | mytomocine C | |
dc.subject | antioxidative enzyme | |
dc.title | Size distribution of fullerenol nanoparticles in cell culture medium and
their influence on antioxidative enzymes in Chinese hamster ovary cells | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Славиц, Марија Н.; Срдјеновиц, Бранислава У.; Станков, Кармен М.; Кладар, Небојса В.; Јовиц, Даница С.; Секе, Мариана Н.; Богдановиц, Висња В.; | |
dc.citation.issue | 4 | |
dc.citation.volume | 69 | |
dc.identifier.doi | 10.2298/HEMIND131218054S | |
dc.identifier.scopus | 2-s2.0-84939787369 | |
dc.identifier.wos | 000362801700012 | |
dc.citation.spage | 425 | |
dc.citation.epage | 431 | |
dc.type.version | publishedVersion | en |