TY  - JOUR
AU  - Bolic, Bojana
AU  - Mijuskovic, Ana
AU  - Popovic-Bijelic, Ana
AU  - Nikolić-Kokić, Aleksandra
AU  - Spasic, Snezana
AU  - Blagojević, Duško
AU  - Spasić, Mihajlo
AU  - Spasojevic, Ivan
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2329
AB  - Interactions of hydrogen sulfide (HS-/H2S), a reducing signaling
   species, with superoxide dimutases (SOD) are poorly understood. We
   applied low-T EPR spectroscopy to examine the effects of HS-/H2S and
   superoxide radical anion (O-2(-)) on metallocenters of FeSOD, MnSOD, and
   CuZnSOD. HS-/H2S did not affect FeSOD, whereas active centers of MnSOD
   and CuZnSOD were open to this agent. Cu2+ was reduced to Cu1+, while
   manganese appears to be released from MnSOD active center. Untreated and
   O-2(-) treated FeSOD and MnSOD predominantly show 5 d-electron systems,
   i.e. Fe3+ and Mn2+. Our study provides new details on the mechanisms of
   (patho)physiological effects of HS-/H2S. (C) 2015 Elsevier Inc. All
   rights reserved.
T2  - Nitric Oxide-Biology and Chemistry
T1  - Reactions of superoxide dismutases with HS-/H2S and superoxide radical
 anion: An in vitro EPR study
VL  - 51
DO  - 10.1016/j.niox.2015.09.008
SP  - 19
EP  - 23
ER  - 

@article{
author = "Bolic, Bojana and Mijuskovic, Ana and Popovic-Bijelic, Ana and Nikolić-Kokić, Aleksandra and Spasic, Snezana and Blagojević, Duško and Spasić, Mihajlo and Spasojevic, Ivan",
year = "2015",
abstract = "Interactions of hydrogen sulfide (HS-/H2S), a reducing signaling
   species, with superoxide dimutases (SOD) are poorly understood. We
   applied low-T EPR spectroscopy to examine the effects of HS-/H2S and
   superoxide radical anion (O-2(-)) on metallocenters of FeSOD, MnSOD, and
   CuZnSOD. HS-/H2S did not affect FeSOD, whereas active centers of MnSOD
   and CuZnSOD were open to this agent. Cu2+ was reduced to Cu1+, while
   manganese appears to be released from MnSOD active center. Untreated and
   O-2(-) treated FeSOD and MnSOD predominantly show 5 d-electron systems,
   i.e. Fe3+ and Mn2+. Our study provides new details on the mechanisms of
   (patho)physiological effects of HS-/H2S. (C) 2015 Elsevier Inc. All
   rights reserved.",
journal = "Nitric Oxide-Biology and Chemistry",
title = "Reactions of superoxide dismutases with HS-/H2S and superoxide radical
 anion: An in vitro EPR study",
volume = "51",
doi = "10.1016/j.niox.2015.09.008",
pages = "19-23"
}

Bolic, B., Mijuskovic, A., Popovic-Bijelic, A., Nikolić-Kokić, A., Spasic, S., Blagojević, D., Spasić, M.,& Spasojevic, I.. (2015). Reactions of superoxide dismutases with HS-/H2S and superoxide radical
 anion: An in vitro EPR study. in Nitric Oxide-Biology and Chemistry, 51, 19-23.
https://doi.org/10.1016/j.niox.2015.09.008

Bolic B, Mijuskovic A, Popovic-Bijelic A, Nikolić-Kokić A, Spasic S, Blagojević D, Spasić M, Spasojevic I. Reactions of superoxide dismutases with HS-/H2S and superoxide radical
 anion: An in vitro EPR study. in Nitric Oxide-Biology and Chemistry. 2015;51:19-23.
doi:10.1016/j.niox.2015.09.008 .

Bolic, Bojana, Mijuskovic, Ana, Popovic-Bijelic, Ana, Nikolić-Kokić, Aleksandra, Spasic, Snezana, Blagojević, Duško, Spasić, Mihajlo, Spasojevic, Ivan, "Reactions of superoxide dismutases with HS-/H2S and superoxide radical
 anion: An in vitro EPR study" in Nitric Oxide-Biology and Chemistry, 51 (2015):19-23,
https://doi.org/10.1016/j.niox.2015.09.008 . .

TY  - JOUR
AU  - Ristic, Aleksandar J.
AU  - Sokic, Dragoslav
AU  - Bascarevic, Vladimir
AU  - Spasic, Snezana
AU  - Vojvodic, Nikola
AU  - Savic, Slobodan
AU  - Raicevic, Savo
AU  - Kovacevic, Masa
AU  - Savić, Danijela
AU  - Spasojevic, Ivan
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2214
AB  - An altered metal and electrolyte profile has been implicated in the
   pathologic mechanisms of chronic epilepsy; however, no study has
   comprehensively measured hippocampal concentrations of these elements in
   patients with mesial temporal lobe epilepsy and hippocampal sclerosis
   (mTLE-HS). We therefore analyzed hippocampi of 24 patients with
   drug-resistant mTLE-HS (mean age 35.69.4years) who underwent anterior
   temporal lobe resection and amygdalohippocampectomy and 17 hippocampi
   obtained by autopsy from 13 controls (mean age 40.5 +/- 12.9years),
   using inductively coupled plasma optical emission spectrometry
   (ICP-OES). Epileptic hippocampi showed significantly lower
   concentrations (g/g of tissue) of copper (HS: 2.34 +/- 0.12; control
   {[}C]: 3.57 +/- 0.33; p<0.001), manganese (HS: 0.205 +/- 0.030; C: 0.409
   +/- 0.064; p=0.004), and potassium (HS: 2,001 +/- 59; C: 2,322 +/- 61;
   p<0.001), and increased sodium levels (HS: 1,131 +/- 22; C: 1,040 +/-
   25; p=0.010). Zinc, iron, calcium, and magnesium levels did not differ
   in HS and controls. In summary, copper and manganese levels are
   deficient, whereas iron level is unchanged in hippocampi from patients
   with mTLE-HS. Our results provide a basis for understanding the
   potential involvement of different metals and electrolytes in the
   pathology of HS. A PowerPoint slide summarizing this article is
   available for download in the Supporting Information section .
T2  - Epilepsia
T1  - Metals and electrolytes in sclerotic hippocampi in patients with
 drug-resistant mesial temporal lobe epilepsy
IS  - 5
VL  - 55
DO  - 10.1111/epi.12593
SP  - E34
EP  - E37
ER  - 

@article{
author = "Ristic, Aleksandar J. and Sokic, Dragoslav and Bascarevic, Vladimir and Spasic, Snezana and Vojvodic, Nikola and Savic, Slobodan and Raicevic, Savo and Kovacevic, Masa and Savić, Danijela and Spasojevic, Ivan",
year = "2014",
abstract = "An altered metal and electrolyte profile has been implicated in the
   pathologic mechanisms of chronic epilepsy; however, no study has
   comprehensively measured hippocampal concentrations of these elements in
   patients with mesial temporal lobe epilepsy and hippocampal sclerosis
   (mTLE-HS). We therefore analyzed hippocampi of 24 patients with
   drug-resistant mTLE-HS (mean age 35.69.4years) who underwent anterior
   temporal lobe resection and amygdalohippocampectomy and 17 hippocampi
   obtained by autopsy from 13 controls (mean age 40.5 +/- 12.9years),
   using inductively coupled plasma optical emission spectrometry
   (ICP-OES). Epileptic hippocampi showed significantly lower
   concentrations (g/g of tissue) of copper (HS: 2.34 +/- 0.12; control
   {[}C]: 3.57 +/- 0.33; p<0.001), manganese (HS: 0.205 +/- 0.030; C: 0.409
   +/- 0.064; p=0.004), and potassium (HS: 2,001 +/- 59; C: 2,322 +/- 61;
   p<0.001), and increased sodium levels (HS: 1,131 +/- 22; C: 1,040 +/-
   25; p=0.010). Zinc, iron, calcium, and magnesium levels did not differ
   in HS and controls. In summary, copper and manganese levels are
   deficient, whereas iron level is unchanged in hippocampi from patients
   with mTLE-HS. Our results provide a basis for understanding the
   potential involvement of different metals and electrolytes in the
   pathology of HS. A PowerPoint slide summarizing this article is
   available for download in the Supporting Information section .",
journal = "Epilepsia",
title = "Metals and electrolytes in sclerotic hippocampi in patients with
 drug-resistant mesial temporal lobe epilepsy",
number = "5",
volume = "55",
doi = "10.1111/epi.12593",
pages = "E34-E37"
}

Ristic, A. J., Sokic, D., Bascarevic, V., Spasic, S., Vojvodic, N., Savic, S., Raicevic, S., Kovacevic, M., Savić, D.,& Spasojevic, I.. (2014). Metals and electrolytes in sclerotic hippocampi in patients with
 drug-resistant mesial temporal lobe epilepsy. in Epilepsia, 55(5), E34-E37.
https://doi.org/10.1111/epi.12593

Ristic AJ, Sokic D, Bascarevic V, Spasic S, Vojvodic N, Savic S, Raicevic S, Kovacevic M, Savić D, Spasojevic I. Metals and electrolytes in sclerotic hippocampi in patients with
 drug-resistant mesial temporal lobe epilepsy. in Epilepsia. 2014;55(5):E34-E37.
doi:10.1111/epi.12593 .

Ristic, Aleksandar J., Sokic, Dragoslav, Bascarevic, Vladimir, Spasic, Snezana, Vojvodic, Nikola, Savic, Slobodan, Raicevic, Savo, Kovacevic, Masa, Savić, Danijela, Spasojevic, Ivan, "Metals and electrolytes in sclerotic hippocampi in patients with
 drug-resistant mesial temporal lobe epilepsy" in Epilepsia, 55, no. 5 (2014):E34-E37,
https://doi.org/10.1111/epi.12593 . .