TY  - JOUR
AU  - Kolarević, Stoimir
AU  - Kračun-Kolarević, Margareta
AU  - Jovanović Marić, Jovana
AU  - Đorđević, Jelena
AU  - Vuković-Gačić, Branka
AU  - Joksimović, Danijela
AU  - Martinović, Rajko
AU  - Bajt, Oliver
AU  - Ramšak, Andreja
PY  - 2023
UR  - https://academic.oup.com/mutage/advance-article/doi/10.1093/mutage/geac017/6694788
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5121
AB  - In this study, the possible 'vector effect' within the exposure of Mediterranean mussels (Mytilus galloprovincialis) to polystyrene microplastics with adsorbed fluoranthene was investigated by applying the multibiomarker approach. The major focus was placed on genotoxicological endpoints as to our knowledge there are no literature data on the genotoxicity of polystyrene microparticles alone or with adsorbed fluoranthene in the selected experimental organisms. DNA damage was assessed in haemocytes by comet assay and micronucleus test. For the assessment of neurotoxicity, acetylcholinesterase activity was measured in gills. Glutathione S-transferase was assessed in gills and hepatopancreas since these enzymes are induced for biotransformation and excretion of lipophilic compounds such as hydrocarbons. Finally, differences in physiological response within the exposure to polystyrene particles, fluoranthene, or particles with adsorbed fluoranthene were assessed by the variation of heart rate patterns studied by the noninvasive laser fibre-optic method. The uniform response of individual biomarkers within the exposure groups was not recorded. There was no clear pattern in variation of acetylcholinesterase or glutathione S-transferase activity which could be attributed to the treatment. Exposure to polystyrene increased DNA damage which was detected by the comet assay but was not confirmed by micronucleus formation. Data of genotoxicity assays indicated differential responses among the groups exposed to fluoranthene alone and fluoranthene adsorbed to polystyrene. Change in the heart rate patterns within the studied groups supports the concept of the Trojan horse effect within the exposure to polystyrene particles with adsorbed fluoranthene.
PB  - Oxford: Oxford University Press
T2  - Mutagenesis
T1  - Single and combined potential of polystyrene microparticles and fluoranthene in the induction of DNA damage in haemocytes of Mediterranean mussel (Mytilus galloprovincialis).
IS  - 1
VL  - 38
DO  - 10.1093/mutage/geac017
SP  - 3
EP  - 12
ER  - 

@article{
author = "Kolarević, Stoimir and Kračun-Kolarević, Margareta and Jovanović Marić, Jovana and Đorđević, Jelena and Vuković-Gačić, Branka and Joksimović, Danijela and Martinović, Rajko and Bajt, Oliver and Ramšak, Andreja",
year = "2023",
abstract = "In this study, the possible 'vector effect' within the exposure of Mediterranean mussels (Mytilus galloprovincialis) to polystyrene microplastics with adsorbed fluoranthene was investigated by applying the multibiomarker approach. The major focus was placed on genotoxicological endpoints as to our knowledge there are no literature data on the genotoxicity of polystyrene microparticles alone or with adsorbed fluoranthene in the selected experimental organisms. DNA damage was assessed in haemocytes by comet assay and micronucleus test. For the assessment of neurotoxicity, acetylcholinesterase activity was measured in gills. Glutathione S-transferase was assessed in gills and hepatopancreas since these enzymes are induced for biotransformation and excretion of lipophilic compounds such as hydrocarbons. Finally, differences in physiological response within the exposure to polystyrene particles, fluoranthene, or particles with adsorbed fluoranthene were assessed by the variation of heart rate patterns studied by the noninvasive laser fibre-optic method. The uniform response of individual biomarkers within the exposure groups was not recorded. There was no clear pattern in variation of acetylcholinesterase or glutathione S-transferase activity which could be attributed to the treatment. Exposure to polystyrene increased DNA damage which was detected by the comet assay but was not confirmed by micronucleus formation. Data of genotoxicity assays indicated differential responses among the groups exposed to fluoranthene alone and fluoranthene adsorbed to polystyrene. Change in the heart rate patterns within the studied groups supports the concept of the Trojan horse effect within the exposure to polystyrene particles with adsorbed fluoranthene.",
publisher = "Oxford: Oxford University Press",
journal = "Mutagenesis",
title = "Single and combined potential of polystyrene microparticles and fluoranthene in the induction of DNA damage in haemocytes of Mediterranean mussel (Mytilus galloprovincialis).",
number = "1",
volume = "38",
doi = "10.1093/mutage/geac017",
pages = "3-12"
}

Kolarević, S., Kračun-Kolarević, M., Jovanović Marić, J., Đorđević, J., Vuković-Gačić, B., Joksimović, D., Martinović, R., Bajt, O.,& Ramšak, A.. (2023). Single and combined potential of polystyrene microparticles and fluoranthene in the induction of DNA damage in haemocytes of Mediterranean mussel (Mytilus galloprovincialis).. in Mutagenesis
Oxford: Oxford University Press., 38(1), 3-12.
https://doi.org/10.1093/mutage/geac017

Kolarević S, Kračun-Kolarević M, Jovanović Marić J, Đorđević J, Vuković-Gačić B, Joksimović D, Martinović R, Bajt O, Ramšak A. Single and combined potential of polystyrene microparticles and fluoranthene in the induction of DNA damage in haemocytes of Mediterranean mussel (Mytilus galloprovincialis).. in Mutagenesis. 2023;38(1):3-12.
doi:10.1093/mutage/geac017 .

Kolarević, Stoimir, Kračun-Kolarević, Margareta, Jovanović Marić, Jovana, Đorđević, Jelena, Vuković-Gačić, Branka, Joksimović, Danijela, Martinović, Rajko, Bajt, Oliver, Ramšak, Andreja, "Single and combined potential of polystyrene microparticles and fluoranthene in the induction of DNA damage in haemocytes of Mediterranean mussel (Mytilus galloprovincialis)." in Mutagenesis, 38, no. 1 (2023):3-12,
https://doi.org/10.1093/mutage/geac017 . .

TY  - CONF
AU  - Martinović, Rajko
AU  - Kolarević, Stoimir
AU  - Kračun-Kolarević, Margareta
AU  - Đorđević, Jelena
AU  - Jovanović Marić, Jovana
AU  - Gačić, Zoran
AU  - Vuković-Gačić, Branka
AU  - Petrošević Bajčeta, Ana
AU  - Joksimović, Danijela
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5726
AB  - More frequent application of biological parameters beside the conventional chemical parameters in national
monitoring for marine ecosystem assessment is supported by UNEP/MAP. Accordingly, to evaluate the
possible effects of pollution by determination of trace element content and genotoxicity assessment in
marine organisms within the Boka Kotorska Bay, Montenegro (southern Adriatic), we carried a field study
which included transplantation of the seabream (Sparus aurata) from aquaculture farm (Orahovac) to more
impacted sites (Dobrota and port of Tivat), situated in vicinity of the main ports. On the sampling site
Orahovac, the group of seabream specimens were placed in closed fish trap on 5 m depth (O1), another fish
trap was placed in Dobrota, while the third fish trap with seabreams was placed at the site port of Tivat.
The additional group was sampled from standard aquaculture cage on sampling site (O2) to reduce possible
bias in genotoxicity data due to confined space within the fish trap. After two weeks of exposure, blood
from fish heart was taken, afterwards muscle tissues were prepared for trace element determination.
Genotoxicity was measured by DNA damage induction based on comet (single cell gel electrophoresis)
assay parameter – Tail intensity (TI%), while trace element (As, Cd, Pb, Hg, Cr, Cu, Fe, Mn, Ni, Zn and
V) content was determined by ICP. Mean values of TI% obtained from seabream specimens at the sampling
site Orahovac were: 4.26 ± 0.17 – O1 and 2.56 ± 0.11 – O2, while TI% values for transplanted specimens
on the sites Dobrota and port of Tivat were 6.38 ± 0.17 and 11.06 ± 0.23, respectively. Statistically
significant differences (p<0,05) of TI% were observed between all specimens groups. The group of
seabream from port of Tivat showed the highest TI% (higher level of DNA damage), most probably caused
by marine pollution. Obtained trace element concentrations in seabream tissues were significantly lower in
comparison to values recommended by FAO, EC and national legislatives of Croatia, Spain and Turkey.
Since transplanted fish showed a significant response in a relatively short exposure period, our results
support the introduction of seabream caging as monitoring tool to reveal marine pollution by multiple
biomarker approach. Considering the significant share of aquacultured seabream in human consumption,
higher availability for sampling and convenience in application for molecular biomarker analyses in the
same samples, such an integrated monitoring approach would contribute to more credible data.
PB  - Split: Institute of Oceanography and Fisheries
C3  - Book of Abstracts: 2nd Southeast European Ichthyological Conference (SEEIC); 2022 Oct 12-15; Brač Island, Croatia
T1  - Transplant caging of seabream (Sparus aurata) as a monitoring tool for marine pollution assessment in the Montenegrin Adriatic coast
SP  - 33
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5726
ER  - 

@conference{
author = "Martinović, Rajko and Kolarević, Stoimir and Kračun-Kolarević, Margareta and Đorđević, Jelena and Jovanović Marić, Jovana and Gačić, Zoran and Vuković-Gačić, Branka and Petrošević Bajčeta, Ana and Joksimović, Danijela",
year = "2022",
abstract = "More frequent application of biological parameters beside the conventional chemical parameters in national
monitoring for marine ecosystem assessment is supported by UNEP/MAP. Accordingly, to evaluate the
possible effects of pollution by determination of trace element content and genotoxicity assessment in
marine organisms within the Boka Kotorska Bay, Montenegro (southern Adriatic), we carried a field study
which included transplantation of the seabream (Sparus aurata) from aquaculture farm (Orahovac) to more
impacted sites (Dobrota and port of Tivat), situated in vicinity of the main ports. On the sampling site
Orahovac, the group of seabream specimens were placed in closed fish trap on 5 m depth (O1), another fish
trap was placed in Dobrota, while the third fish trap with seabreams was placed at the site port of Tivat.
The additional group was sampled from standard aquaculture cage on sampling site (O2) to reduce possible
bias in genotoxicity data due to confined space within the fish trap. After two weeks of exposure, blood
from fish heart was taken, afterwards muscle tissues were prepared for trace element determination.
Genotoxicity was measured by DNA damage induction based on comet (single cell gel electrophoresis)
assay parameter – Tail intensity (TI%), while trace element (As, Cd, Pb, Hg, Cr, Cu, Fe, Mn, Ni, Zn and
V) content was determined by ICP. Mean values of TI% obtained from seabream specimens at the sampling
site Orahovac were: 4.26 ± 0.17 – O1 and 2.56 ± 0.11 – O2, while TI% values for transplanted specimens
on the sites Dobrota and port of Tivat were 6.38 ± 0.17 and 11.06 ± 0.23, respectively. Statistically
significant differences (p<0,05) of TI% were observed between all specimens groups. The group of
seabream from port of Tivat showed the highest TI% (higher level of DNA damage), most probably caused
by marine pollution. Obtained trace element concentrations in seabream tissues were significantly lower in
comparison to values recommended by FAO, EC and national legislatives of Croatia, Spain and Turkey.
Since transplanted fish showed a significant response in a relatively short exposure period, our results
support the introduction of seabream caging as monitoring tool to reveal marine pollution by multiple
biomarker approach. Considering the significant share of aquacultured seabream in human consumption,
higher availability for sampling and convenience in application for molecular biomarker analyses in the
same samples, such an integrated monitoring approach would contribute to more credible data.",
publisher = "Split: Institute of Oceanography and Fisheries",
journal = "Book of Abstracts: 2nd Southeast European Ichthyological Conference (SEEIC); 2022 Oct 12-15; Brač Island, Croatia",
title = "Transplant caging of seabream (Sparus aurata) as a monitoring tool for marine pollution assessment in the Montenegrin Adriatic coast",
pages = "33",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5726"
}

Martinović, R., Kolarević, S., Kračun-Kolarević, M., Đorđević, J., Jovanović Marić, J., Gačić, Z., Vuković-Gačić, B., Petrošević Bajčeta, A.,& Joksimović, D.. (2022). Transplant caging of seabream (Sparus aurata) as a monitoring tool for marine pollution assessment in the Montenegrin Adriatic coast. in Book of Abstracts: 2nd Southeast European Ichthyological Conference (SEEIC); 2022 Oct 12-15; Brač Island, Croatia
Split: Institute of Oceanography and Fisheries., 33.
https://hdl.handle.net/21.15107/rcub_ibiss_5726

Martinović R, Kolarević S, Kračun-Kolarević M, Đorđević J, Jovanović Marić J, Gačić Z, Vuković-Gačić B, Petrošević Bajčeta A, Joksimović D. Transplant caging of seabream (Sparus aurata) as a monitoring tool for marine pollution assessment in the Montenegrin Adriatic coast. in Book of Abstracts: 2nd Southeast European Ichthyological Conference (SEEIC); 2022 Oct 12-15; Brač Island, Croatia. 2022;:33.
https://hdl.handle.net/21.15107/rcub_ibiss_5726 .

Martinović, Rajko, Kolarević, Stoimir, Kračun-Kolarević, Margareta, Đorđević, Jelena, Jovanović Marić, Jovana, Gačić, Zoran, Vuković-Gačić, Branka, Petrošević Bajčeta, Ana, Joksimović, Danijela, "Transplant caging of seabream (Sparus aurata) as a monitoring tool for marine pollution assessment in the Montenegrin Adriatic coast" in Book of Abstracts: 2nd Southeast European Ichthyological Conference (SEEIC); 2022 Oct 12-15; Brač Island, Croatia (2022):33,
https://hdl.handle.net/21.15107/rcub_ibiss_5726 .

TY  - CHAP
AU  - Kolarević, Stoimir
AU  - Kračun-Kolarević, Margareta
AU  - Jovanović, Jovana
AU  - Ilić, Marija
AU  - Paunović, Momir
AU  - Kostić-Vuković, Jovana
AU  - Martinović, Rajko
AU  - Jokanović, Sandra
AU  - Joksimović, Danijela
AU  - Pešić, Vladimir
AU  - Kirschner, Alexander K. T.
AU  - Linke, Rita
AU  - Ixenmaier, Simone
AU  - Farnleitner, Andreas
AU  - Savio, Domenico
AU  - Reischer, Georg
AU  - Tomić, Nevenka
AU  - Vuković-Gačić, Branka
PY  - 2020
UR  - https://link.springer.com/chapter/10.1007/698_2019_420
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3952
AB  - The literature data on the microbiological water quality of the surface and groundwaters in Montenegro is very scarce. Therefore, this chapter aims to provide an insight in the microbiological water quality of rivers in Montenegro by compiling the data obtained in period 2009–2018 in national monitoring program and the data collected within the Montenegro survey in 2019 with an emphasis on the hotspots of faecal pollution and possible sources of pollution. Despite the high risk that poor implementation of wastewater treatment might represent for Montenegro, the obtained dataset indicates that overall microbiological water quality of rivers in Montenegro is quite good. About 80% of the investigated sites have bathing water quality according to Montenegrin legislation. Only four sites were identified as hotspots of faecal pollution where the human source of pollution prevails.
PB  - Springer
T2  - The Rivers of Montenegro
T2  - The Rivers of Montenegro
T1  - Microbiological Water Quality of Rivers in Montenegro
DO  - 10.1007/698_2019_420
SP  - 135
EP  - 155
ER  - 

@inbook{
editor = "Pešić, Vladimir, Paunović, Momir, Kostianoy, Andrey G.",
author = "Kolarević, Stoimir and Kračun-Kolarević, Margareta and Jovanović, Jovana and Ilić, Marija and Paunović, Momir and Kostić-Vuković, Jovana and Martinović, Rajko and Jokanović, Sandra and Joksimović, Danijela and Pešić, Vladimir and Kirschner, Alexander K. T. and Linke, Rita and Ixenmaier, Simone and Farnleitner, Andreas and Savio, Domenico and Reischer, Georg and Tomić, Nevenka and Vuković-Gačić, Branka",
year = "2020",
abstract = "The literature data on the microbiological water quality of the surface and groundwaters in Montenegro is very scarce. Therefore, this chapter aims to provide an insight in the microbiological water quality of rivers in Montenegro by compiling the data obtained in period 2009–2018 in national monitoring program and the data collected within the Montenegro survey in 2019 with an emphasis on the hotspots of faecal pollution and possible sources of pollution. Despite the high risk that poor implementation of wastewater treatment might represent for Montenegro, the obtained dataset indicates that overall microbiological water quality of rivers in Montenegro is quite good. About 80% of the investigated sites have bathing water quality according to Montenegrin legislation. Only four sites were identified as hotspots of faecal pollution where the human source of pollution prevails.",
publisher = "Springer",
journal = "The Rivers of Montenegro, The Rivers of Montenegro",
booktitle = "Microbiological Water Quality of Rivers in Montenegro",
doi = "10.1007/698_2019_420",
pages = "135-155"
}

Pešić, V., Paunović, M., Kostianoy, A. G., Kolarević, S., Kračun-Kolarević, M., Jovanović, J., Ilić, M., Paunović, M., Kostić-Vuković, J., Martinović, R., Jokanović, S., Joksimović, D., Pešić, V., Kirschner, A. K. T., Linke, R., Ixenmaier, S., Farnleitner, A., Savio, D., Reischer, G., Tomić, N.,& Vuković-Gačić, B.. (2020). Microbiological Water Quality of Rivers in Montenegro. in The Rivers of Montenegro
Springer., 135-155.
https://doi.org/10.1007/698_2019_420

Pešić V, Paunović M, Kostianoy AG, Kolarević S, Kračun-Kolarević M, Jovanović J, Ilić M, Paunović M, Kostić-Vuković J, Martinović R, Jokanović S, Joksimović D, Pešić V, Kirschner AKT, Linke R, Ixenmaier S, Farnleitner A, Savio D, Reischer G, Tomić N, Vuković-Gačić B. Microbiological Water Quality of Rivers in Montenegro. in The Rivers of Montenegro. 2020;:135-155.
doi:10.1007/698_2019_420 .

Pešić, Vladimir, Paunović, Momir, Kostianoy, Andrey G., Kolarević, Stoimir, Kračun-Kolarević, Margareta, Jovanović, Jovana, Ilić, Marija, Paunović, Momir, Kostić-Vuković, Jovana, Martinović, Rajko, Jokanović, Sandra, Joksimović, Danijela, Pešić, Vladimir, Kirschner, Alexander K. T., Linke, Rita, Ixenmaier, Simone, Farnleitner, Andreas, Savio, Domenico, Reischer, Georg, Tomić, Nevenka, Vuković-Gačić, Branka, "Microbiological Water Quality of Rivers in Montenegro" in The Rivers of Montenegro (2020):135-155,
https://doi.org/10.1007/698_2019_420 . .

TY  - CONF
AU  - Raković, Maja
AU  - Joksimović, Aleksandar
AU  - Đurović, Mirko
AU  - Marković, Olivera
AU  - Joksimović, Danijela
AU  - Pešić, Ana
AU  - Ikica, Zdravko
AU  - Mihailović, Mirjana
AU  - Paunović, Momir
PY  - 2017
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4842
AB  - Mediterranean mussel (Mytilus galloprovincialis) is a recognized as an ideal bioindicator in 
monitoring of the marine ecosystem due to the ability of accumulation of various pollutants. 
Mullus barbatus and Parapaeneus longirostris are economically important demersal 
species in the trawl fishing on the shelf of the Montenegrin coast. In these investigations we 
were measured the total length, weight and gender for total of 193 specimens of surmullet,
shrimp and mussel. The obtained results of basic parameters of population dynamics, 
selected marine species, they were part of the monitoring of demersal resources. Further 
research will be directed and on the oxidative stress parameters, in aim of monitoring 
quality of the ecosystem of the bay of Kotor.
AB  - Mediteranska dagnja (Mytilus galloprovincialis) je prepoznata kao idealan bioindikator u
monitoringu morskog ekosistema zbog sposobnosti akumulacije raznih polutanata, dok su
barbun - Mullus barbatus i kozica - Parapaeneus longirostris ekonomski najznačajnije demerzalne vrste u kočarskom ribolovu na šelfu Crnogorskog primorja. U ovim istraživanjima određena je ukupna dužina, težina i pol za 193 jedinke barbuna, kozica i
školjki. Dobijeni rezultati osnovnih parametara populacione dinamike odabranih
konzumnih vrsta morskih organizama predstavljaju deo monitoringa demerzalnih resursa.
Istraživanja će biti usmerena i na komponente antioksidacione zaštite organizma od
oksidativnog stresa u cilju praćenja kvaliteta ekositetma Bokokotorskog zaliva.
PB  - Belgarde: Serbian Association for Water Protection
C3  - Water 2017 : Conference Proceedings 46th Annual Conference of the Serbian Water Pollution Control Society, Vršac, 6-8. jun 2017
T1  - Ribe, rakovi i školjke kao bioindikatori ekološkog stanja ekosistema bokokotorskog zaliva
T1  - Fish, crustaceans and mussels as bioindicators of ecological condition ecosystem of the Bay of Kotor
SP  - 217
EP  - 224
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_4842
ER  - 

@conference{
author = "Raković, Maja and Joksimović, Aleksandar and Đurović, Mirko and Marković, Olivera and Joksimović, Danijela and Pešić, Ana and Ikica, Zdravko and Mihailović, Mirjana and Paunović, Momir",
year = "2017",
abstract = "Mediterranean mussel (Mytilus galloprovincialis) is a recognized as an ideal bioindicator in 
monitoring of the marine ecosystem due to the ability of accumulation of various pollutants. 
Mullus barbatus and Parapaeneus longirostris are economically important demersal 
species in the trawl fishing on the shelf of the Montenegrin coast. In these investigations we 
were measured the total length, weight and gender for total of 193 specimens of surmullet,
shrimp and mussel. The obtained results of basic parameters of population dynamics, 
selected marine species, they were part of the monitoring of demersal resources. Further 
research will be directed and on the oxidative stress parameters, in aim of monitoring 
quality of the ecosystem of the bay of Kotor., Mediteranska dagnja (Mytilus galloprovincialis) je prepoznata kao idealan bioindikator u
monitoringu morskog ekosistema zbog sposobnosti akumulacije raznih polutanata, dok su
barbun - Mullus barbatus i kozica - Parapaeneus longirostris ekonomski najznačajnije demerzalne vrste u kočarskom ribolovu na šelfu Crnogorskog primorja. U ovim istraživanjima određena je ukupna dužina, težina i pol za 193 jedinke barbuna, kozica i
školjki. Dobijeni rezultati osnovnih parametara populacione dinamike odabranih
konzumnih vrsta morskih organizama predstavljaju deo monitoringa demerzalnih resursa.
Istraživanja će biti usmerena i na komponente antioksidacione zaštite organizma od
oksidativnog stresa u cilju praćenja kvaliteta ekositetma Bokokotorskog zaliva.",
publisher = "Belgarde: Serbian Association for Water Protection",
journal = "Water 2017 : Conference Proceedings 46th Annual Conference of the Serbian Water Pollution Control Society, Vršac, 6-8. jun 2017",
title = "Ribe, rakovi i školjke kao bioindikatori ekološkog stanja ekosistema bokokotorskog zaliva, Fish, crustaceans and mussels as bioindicators of ecological condition ecosystem of the Bay of Kotor",
pages = "217-224",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_4842"
}

Raković, M., Joksimović, A., Đurović, M., Marković, O., Joksimović, D., Pešić, A., Ikica, Z., Mihailović, M.,& Paunović, M.. (2017). Ribe, rakovi i školjke kao bioindikatori ekološkog stanja ekosistema bokokotorskog zaliva. in Water 2017 : Conference Proceedings 46th Annual Conference of the Serbian Water Pollution Control Society, Vršac, 6-8. jun 2017
Belgarde: Serbian Association for Water Protection., 217-224.
https://hdl.handle.net/21.15107/rcub_ibiss_4842

Raković M, Joksimović A, Đurović M, Marković O, Joksimović D, Pešić A, Ikica Z, Mihailović M, Paunović M. Ribe, rakovi i školjke kao bioindikatori ekološkog stanja ekosistema bokokotorskog zaliva. in Water 2017 : Conference Proceedings 46th Annual Conference of the Serbian Water Pollution Control Society, Vršac, 6-8. jun 2017. 2017;:217-224.
https://hdl.handle.net/21.15107/rcub_ibiss_4842 .

Raković, Maja, Joksimović, Aleksandar, Đurović, Mirko, Marković, Olivera, Joksimović, Danijela, Pešić, Ana, Ikica, Zdravko, Mihailović, Mirjana, Paunović, Momir, "Ribe, rakovi i školjke kao bioindikatori ekološkog stanja ekosistema bokokotorskog zaliva" in Water 2017 : Conference Proceedings 46th Annual Conference of the Serbian Water Pollution Control Society, Vršac, 6-8. jun 2017 (2017):217-224,
https://hdl.handle.net/21.15107/rcub_ibiss_4842 .

TY  - JOUR
AU  - Mihailović, Mirjana
AU  - Petrović, Miodrag
AU  - Grdović, Nevena
AU  - Dinić, Svetlana
AU  - Uskoković, Aleksandra
AU  - Vidaković, Melita
AU  - Grigorov, Ilijana
AU  - Bogojević, Desanka
AU  - Ivanović Matić, Svetlana
AU  - Martinović, Vesna
AU  - Arambašić Jovanović, Jelena
AU  - Joksimović, Danijela
AU  - Labus-Blagojević, Svetlana
AU  - Poznanović, Goran
PY  - 2010
PY  - 2010
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/561
AB  - The enzyme CYP1A is an established biomarker of fish exposure to polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs). The metallothioneins (MT), a family of Cys-rich proteins, bind a wide range of metals and participate in their metabolism. The aim of the study was to examine the correlation between CYP1A and MT expression in commercially important fish species Mullus barbatus and Merluccius merluccius and contaminants (PAHs, PCBs, toxic metals) in seawater and sediment from three localities with different level of contamination in the Adriatic Sea in winter, i.e., Platamuni, Valdanos and the port of Bar. The relative concentration of CYP1A was the highest in both fish species from Bar. Increased concentrations of PCBs in the seawater were observed only in Bar. A species-specific higher increase in the protein concentration of CYP1A was observed in Mullus barbatus compared to Merluccius merluccius. The levels of MT were the highest in Merluccius merluccius from Bar and in Mullus barbatus from Valdanos. The induction of MT correlated with the elevated concentrations of Cu and Pb determined by chemical analysis of the seawater from Bar and Valdanos, respectively. According to the chemical analysis of the seawater and the biological response of the fish, the Platamuni locality exhibited the lowest level of contamination.
AB  - CYP1A predstavlja dobro okarakterisan biomarker kod riba pri izlaganju policikličnim aromatičnim ugljovodonicima (PAH) i policikličnim bifeholima (PCB). Metalotioneini (MT) pretstavljaju familiju proteina koji vezuju metale i učestvuju u njihovoj metabolizmu, transportu i regulaciji. Cilj ovog rada je bio da se ispitaju korelacije između promena u nivou CYP1A i MT u hepatopankreasu dve komercijalno važne ribe: Mullus barbatus (trlja) i Merluccius merluccius (oslić) i kontaminanatata: PAH, PCB i toksičnih metala) na tri lokaliteta u Jadrnskom moru (Platamuni, Valdanos i luka Bar) u zimu. CYP1A je u najvećem stepenu indukovan na lokalitetu Bar u obe ispitivane vrste, što je u korelaciji sa prisustvom povećane količine PCB u morskoj vodi u Baru. Nivo MT je najveći kod oslića izlovljenog u Baru, a kod trlje u Valdanosu. To je u korelaciji sa izmerenim povećanim koncentracijama bakra u Baru, a olova u Valdanosu. Na osnovu izučavanih parametara, Platamuni su lokalitet sa najmanjim stepenom kontaminacije.
PB  - Belgrade: Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Ekspresija CYPLA i metalotioneina u hepatopankreasu oslića i trlje iz Jadranskog mora
T1  - CYP1A and metallothionein expression in the hepatopancreas of merluccius merluccius and mullus barbatus from the Adriatic sea
IS  - 8
VL  - 75
DO  - 10.2298/JSC091029083M
SP  - 1149
EP  - 1159
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_561
ER  - 

@article{
author = "Mihailović, Mirjana and Petrović, Miodrag and Grdović, Nevena and Dinić, Svetlana and Uskoković, Aleksandra and Vidaković, Melita and Grigorov, Ilijana and Bogojević, Desanka and Ivanović Matić, Svetlana and Martinović, Vesna and Arambašić Jovanović, Jelena and Joksimović, Danijela and Labus-Blagojević, Svetlana and Poznanović, Goran",
year = "2010, 2010",
abstract = "The enzyme CYP1A is an established biomarker of fish exposure to polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs). The metallothioneins (MT), a family of Cys-rich proteins, bind a wide range of metals and participate in their metabolism. The aim of the study was to examine the correlation between CYP1A and MT expression in commercially important fish species Mullus barbatus and Merluccius merluccius and contaminants (PAHs, PCBs, toxic metals) in seawater and sediment from three localities with different level of contamination in the Adriatic Sea in winter, i.e., Platamuni, Valdanos and the port of Bar. The relative concentration of CYP1A was the highest in both fish species from Bar. Increased concentrations of PCBs in the seawater were observed only in Bar. A species-specific higher increase in the protein concentration of CYP1A was observed in Mullus barbatus compared to Merluccius merluccius. The levels of MT were the highest in Merluccius merluccius from Bar and in Mullus barbatus from Valdanos. The induction of MT correlated with the elevated concentrations of Cu and Pb determined by chemical analysis of the seawater from Bar and Valdanos, respectively. According to the chemical analysis of the seawater and the biological response of the fish, the Platamuni locality exhibited the lowest level of contamination., CYP1A predstavlja dobro okarakterisan biomarker kod riba pri izlaganju policikličnim aromatičnim ugljovodonicima (PAH) i policikličnim bifeholima (PCB). Metalotioneini (MT) pretstavljaju familiju proteina koji vezuju metale i učestvuju u njihovoj metabolizmu, transportu i regulaciji. Cilj ovog rada je bio da se ispitaju korelacije između promena u nivou CYP1A i MT u hepatopankreasu dve komercijalno važne ribe: Mullus barbatus (trlja) i Merluccius merluccius (oslić) i kontaminanatata: PAH, PCB i toksičnih metala) na tri lokaliteta u Jadrnskom moru (Platamuni, Valdanos i luka Bar) u zimu. CYP1A je u najvećem stepenu indukovan na lokalitetu Bar u obe ispitivane vrste, što je u korelaciji sa prisustvom povećane količine PCB u morskoj vodi u Baru. Nivo MT je najveći kod oslića izlovljenog u Baru, a kod trlje u Valdanosu. To je u korelaciji sa izmerenim povećanim koncentracijama bakra u Baru, a olova u Valdanosu. Na osnovu izučavanih parametara, Platamuni su lokalitet sa najmanjim stepenom kontaminacije.",
publisher = "Belgrade: Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Ekspresija CYPLA i metalotioneina u hepatopankreasu oslića i trlje iz Jadranskog mora, CYP1A and metallothionein expression in the hepatopancreas of merluccius merluccius and mullus barbatus from the Adriatic sea",
number = "8",
volume = "75",
doi = "10.2298/JSC091029083M",
pages = "1149-1159",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_561"
}

Mihailović, M., Petrović, M., Grdović, N., Dinić, S., Uskoković, A., Vidaković, M., Grigorov, I., Bogojević, D., Ivanović Matić, S., Martinović, V., Arambašić Jovanović, J., Joksimović, D., Labus-Blagojević, S.,& Poznanović, G.. (2010). Ekspresija CYPLA i metalotioneina u hepatopankreasu oslića i trlje iz Jadranskog mora. in Journal of the Serbian Chemical Society
Belgrade: Serbian Chemical Society., 75(8), 1149-1159.
https://doi.org/10.2298/JSC091029083M
https://hdl.handle.net/21.15107/rcub_ibiss_561

Mihailović M, Petrović M, Grdović N, Dinić S, Uskoković A, Vidaković M, Grigorov I, Bogojević D, Ivanović Matić S, Martinović V, Arambašić Jovanović J, Joksimović D, Labus-Blagojević S, Poznanović G. Ekspresija CYPLA i metalotioneina u hepatopankreasu oslića i trlje iz Jadranskog mora. in Journal of the Serbian Chemical Society. 2010;75(8):1149-1159.
doi:10.2298/JSC091029083M
https://hdl.handle.net/21.15107/rcub_ibiss_561 .

Mihailović, Mirjana, Petrović, Miodrag, Grdović, Nevena, Dinić, Svetlana, Uskoković, Aleksandra, Vidaković, Melita, Grigorov, Ilijana, Bogojević, Desanka, Ivanović Matić, Svetlana, Martinović, Vesna, Arambašić Jovanović, Jelena, Joksimović, Danijela, Labus-Blagojević, Svetlana, Poznanović, Goran, "Ekspresija CYPLA i metalotioneina u hepatopankreasu oslića i trlje iz Jadranskog mora" in Journal of the Serbian Chemical Society, 75, no. 8 (2010):1149-1159,
https://doi.org/10.2298/JSC091029083M .,
https://hdl.handle.net/21.15107/rcub_ibiss_561 .

TY  - CONF
AU  - Mihailović, Mirjana
AU  - Petrović, Miodrag
AU  - Grdović, Nevena
AU  - Dinić, Svetlana
AU  - Uskoković, Aleksandra
AU  - Vidaković, Melita
AU  - Grigorov, Ilijana
AU  - Bogojević, Desanka
AU  - Ivanović-Matić, Svetlana
AU  - Martinović, Vesna
AU  - Arambašić Jovanović, Jelena
AU  - Joksimović, Danijela
AU  - Mihajlović, Ranđel
AU  - Labus-Blagojević, Svetlana
AU  - Poznanović, Goran
PY  - 2009
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5442
AB  - CYP1A is an established biomarker of fish exposure to PAHs and PCBs. The metallothioneins (MT)constitute a family of Cys-rich proteins that bind a wide range of metals and participate in their uptake,transport and regulation. The aim of this work was to detect changes in CYP1A and MT protein levelsin the hepatopancreas of two commercially important fish species: Mullus barbatus and Merlucciusmerluccius from three different types of locality in the Adriatic Sea (the open sea area of Platamuni,the port of Bar and Valdanos,) in winter. The relative concentration of CYP1A was highest in bothfish species from Bar. Chemical analysis of sea water did not reveal the presence of PAHs. Increasedconcentrations of PCBs were observed only in Bar. A species-specific and higher increase in the proteinconcentration of CYP1A was observed in Mullus barbatus compared to Merluccius merluccius. Thelevels of MT were highest in Merluccius merluccius from Bar and in Mullus barbatus from Valdanos.Induction of MT correlated with elevated concentrations of Pb and Cu, determined by chemicalanalysis of sea water from Valdanos and Bar, respectively. According to the examined parameters, thePlatamuni locality exhibited the lowest level of contamination.
PB  - Novi Sad: LECOTOX
C3  - Programme and Abstracts: 2nd Rep-lecotox workshop: Trends in ecological risk assessment; 2009 Sep 21-23; Novi Sad, Serbia
T1  - The expression of CYP1A and metallothionein in hepatopancreas of Merluccius merluccius and Mullus barbatus from the Adriatic Sea
SP  - 10
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5442
ER  - 

@conference{
author = "Mihailović, Mirjana and Petrović, Miodrag and Grdović, Nevena and Dinić, Svetlana and Uskoković, Aleksandra and Vidaković, Melita and Grigorov, Ilijana and Bogojević, Desanka and Ivanović-Matić, Svetlana and Martinović, Vesna and Arambašić Jovanović, Jelena and Joksimović, Danijela and Mihajlović, Ranđel and Labus-Blagojević, Svetlana and Poznanović, Goran",
year = "2009",
abstract = "CYP1A is an established biomarker of fish exposure to PAHs and PCBs. The metallothioneins (MT)constitute a family of Cys-rich proteins that bind a wide range of metals and participate in their uptake,transport and regulation. The aim of this work was to detect changes in CYP1A and MT protein levelsin the hepatopancreas of two commercially important fish species: Mullus barbatus and Merlucciusmerluccius from three different types of locality in the Adriatic Sea (the open sea area of Platamuni,the port of Bar and Valdanos,) in winter. The relative concentration of CYP1A was highest in bothfish species from Bar. Chemical analysis of sea water did not reveal the presence of PAHs. Increasedconcentrations of PCBs were observed only in Bar. A species-specific and higher increase in the proteinconcentration of CYP1A was observed in Mullus barbatus compared to Merluccius merluccius. Thelevels of MT were highest in Merluccius merluccius from Bar and in Mullus barbatus from Valdanos.Induction of MT correlated with elevated concentrations of Pb and Cu, determined by chemicalanalysis of sea water from Valdanos and Bar, respectively. According to the examined parameters, thePlatamuni locality exhibited the lowest level of contamination.",
publisher = "Novi Sad: LECOTOX",
journal = "Programme and Abstracts: 2nd Rep-lecotox workshop: Trends in ecological risk assessment; 2009 Sep 21-23; Novi Sad, Serbia",
title = "The expression of CYP1A and metallothionein in hepatopancreas of Merluccius merluccius and Mullus barbatus from the Adriatic Sea",
pages = "10",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5442"
}

Mihailović, M., Petrović, M., Grdović, N., Dinić, S., Uskoković, A., Vidaković, M., Grigorov, I., Bogojević, D., Ivanović-Matić, S., Martinović, V., Arambašić Jovanović, J., Joksimović, D., Mihajlović, R., Labus-Blagojević, S.,& Poznanović, G.. (2009). The expression of CYP1A and metallothionein in hepatopancreas of Merluccius merluccius and Mullus barbatus from the Adriatic Sea. in Programme and Abstracts: 2nd Rep-lecotox workshop: Trends in ecological risk assessment; 2009 Sep 21-23; Novi Sad, Serbia
Novi Sad: LECOTOX., 10.
https://hdl.handle.net/21.15107/rcub_ibiss_5442

Mihailović M, Petrović M, Grdović N, Dinić S, Uskoković A, Vidaković M, Grigorov I, Bogojević D, Ivanović-Matić S, Martinović V, Arambašić Jovanović J, Joksimović D, Mihajlović R, Labus-Blagojević S, Poznanović G. The expression of CYP1A and metallothionein in hepatopancreas of Merluccius merluccius and Mullus barbatus from the Adriatic Sea. in Programme and Abstracts: 2nd Rep-lecotox workshop: Trends in ecological risk assessment; 2009 Sep 21-23; Novi Sad, Serbia. 2009;:10.
https://hdl.handle.net/21.15107/rcub_ibiss_5442 .

Mihailović, Mirjana, Petrović, Miodrag, Grdović, Nevena, Dinić, Svetlana, Uskoković, Aleksandra, Vidaković, Melita, Grigorov, Ilijana, Bogojević, Desanka, Ivanović-Matić, Svetlana, Martinović, Vesna, Arambašić Jovanović, Jelena, Joksimović, Danijela, Mihajlović, Ranđel, Labus-Blagojević, Svetlana, Poznanović, Goran, "The expression of CYP1A and metallothionein in hepatopancreas of Merluccius merluccius and Mullus barbatus from the Adriatic Sea" in Programme and Abstracts: 2nd Rep-lecotox workshop: Trends in ecological risk assessment; 2009 Sep 21-23; Novi Sad, Serbia (2009):10,
https://hdl.handle.net/21.15107/rcub_ibiss_5442 .