TY  - JOUR
AU  - Zivkovic, Jelena
AU  - Barreira, Joao C. M.
AU  - Stojković, Dejan
AU  - Cebovic, Tatjana
AU  - Santos-Buelga, Celestino
AU  - Maksimovic, Zoran
AU  - Ferreira, Isabel C. F. R.
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2196
AB  - The phenolic profile and antibacterial, antimutagenic and antitumour
   activities of the methanolic extracts of Veronica urticifolia Jacq. were
   evaluated. HPLC-DAD/ESI-MS analysis revealed the presence of phenolic
   acids, flavonoids and phenylethanoids, with acteoside as the main
   component (14.9 mg/g of extract). Antibacterial effect was determined
   using the microbroth dilution assay and Staphylococcus aureus was the
   most sensitive strain (MIC and MBC = 7.5 mg/mL). Antimutagenic activity
   was evaluated by Ames mutagenicity assay. At 1 mg/plate, the tested
   extract afforded high protection against the mutagenicity of
   nitroquinoline-N-oxide (4NQO) to Salmonella typhimurium strain TA100
   (inhibition rate 48.3\%). Antitumour activity was screened in Ehrlich
   ascites carcinoma (EAC) model. Pretreatment with 2 mg/kg body weight
   showed statistically significant decrease in tumour cell viability,
   while ascites volume and tumour cell count became slightly decreased,
   but not to a statistically significant extent. The results indicate that
   V. urticifolia deserves further research into its potential
   chemoprevention effects. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Journal of Functional Foods
T1  - Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.
VL  - 9
DO  - 10.1016/j.jff.2014.04.024
SP  - 192
EP  - 201
ER  - 

@article{
author = "Zivkovic, Jelena and Barreira, Joao C. M. and Stojković, Dejan and Cebovic, Tatjana and Santos-Buelga, Celestino and Maksimovic, Zoran and Ferreira, Isabel C. F. R.",
year = "2014",
abstract = "The phenolic profile and antibacterial, antimutagenic and antitumour
   activities of the methanolic extracts of Veronica urticifolia Jacq. were
   evaluated. HPLC-DAD/ESI-MS analysis revealed the presence of phenolic
   acids, flavonoids and phenylethanoids, with acteoside as the main
   component (14.9 mg/g of extract). Antibacterial effect was determined
   using the microbroth dilution assay and Staphylococcus aureus was the
   most sensitive strain (MIC and MBC = 7.5 mg/mL). Antimutagenic activity
   was evaluated by Ames mutagenicity assay. At 1 mg/plate, the tested
   extract afforded high protection against the mutagenicity of
   nitroquinoline-N-oxide (4NQO) to Salmonella typhimurium strain TA100
   (inhibition rate 48.3\%). Antitumour activity was screened in Ehrlich
   ascites carcinoma (EAC) model. Pretreatment with 2 mg/kg body weight
   showed statistically significant decrease in tumour cell viability,
   while ascites volume and tumour cell count became slightly decreased,
   but not to a statistically significant extent. The results indicate that
   V. urticifolia deserves further research into its potential
   chemoprevention effects. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Journal of Functional Foods",
title = "Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.",
volume = "9",
doi = "10.1016/j.jff.2014.04.024",
pages = "192-201"
}

Zivkovic, J., Barreira, J. C. M., Stojković, D., Cebovic, T., Santos-Buelga, C., Maksimovic, Z.,& Ferreira, I. C. F. R.. (2014). Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.. in Journal of Functional Foods, 9, 192-201.
https://doi.org/10.1016/j.jff.2014.04.024

Zivkovic J, Barreira JCM, Stojković D, Cebovic T, Santos-Buelga C, Maksimovic Z, Ferreira ICFR. Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.. in Journal of Functional Foods. 2014;9:192-201.
doi:10.1016/j.jff.2014.04.024 .

Zivkovic, Jelena, Barreira, Joao C. M., Stojković, Dejan, Cebovic, Tatjana, Santos-Buelga, Celestino, Maksimovic, Zoran, Ferreira, Isabel C. F. R., "Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq." in Journal of Functional Foods, 9 (2014):192-201,
https://doi.org/10.1016/j.jff.2014.04.024 . .