dc.creator | Živković, Jelena | |
dc.creator | Stojković, Dejan | |
dc.creator | Petrović, Jovana | |
dc.creator | Zdunić, Gordana | |
dc.creator | Glamočlija, Jasmina | |
dc.creator | Soković, Marina | |
dc.date.accessioned | 2016-05-23T11:00:01Z | |
dc.date.available | 2016-05-23T11:00:01Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 2042-650X | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/2039 | |
dc.description.abstract | Health beneficial properties of Rosa canina species are mainly
attributed to rose hips, while the leaves are usually discarded as
waste. In the present study we investigated chemical constituents as
well as antimicrobial and antibiofilm potential of R. canina methanolic
leaf extract. Chemical analysis showed that dominant phenolic compounds
are quercetin and isorhamnetin derivatives (isoquercetin and
isorhamnetin-3-O-rutinoside). Among the tested bacteria, Pseudomonas
aeruginosa and Salmonella typhimurium were the most susceptible to the
activity of R. canina leaf extract with MIC and MBC values both 0.009 mg
mL(-1). For most of the bacterial strains investigated the extract
showed significantly higher activity compared to the used standard
compounds streptomycin and ampicillin. Also the tested extract
powerfully inhibited in vitro biofilm growth in Pseudomonas aeruginosa,
Staphylococcus aureus, Leishmania monocytogenes and Escherichia coli at
sub MIC-levels. With concentrations equal to 1/4 and 1/8 of MIC values
biofilm growth of P. aeruginosa and E. coli was inhibited by 90\%. The
obtained results are significant for a wider and efficient use of R.
canina leaves. | en |
dc.description.sponsorship | Ministry of Education, Science and Technological Development of Republic
Serbia {[}173032, 46013] | |
dc.language | English | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173032/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/146013/RS// | |
dc.rights | restrictedAccess | |
dc.source | Food & Function | |
dc.title | Rosa canina L. - new possibilities for an old medicinal herb | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Соковић, Марина; Зивковиц, Јелена; Гламоцлија, Јасна; Здуниц, Гордана; Петровиц, Јована; Стојковиц, Дејан; | |
dc.rights.holder | © 2015 The Royal Society of Chemistry | |
dc.citation.issue | 12 | |
dc.citation.volume | 6 | |
dc.description.note | This article has been corrected [http://dx.doi.org/10.1039/c5fo90042e]. | |
dc.identifier.doi | 10.1039/c5fo00820d | |
dc.identifier.scopus | 2-s2.0-84948845033 | |
dc.identifier.wos | 000365924300007 | |
dc.citation.spage | 3687 | |
dc.citation.epage | 3692 | |
dc.type.version | publishedVersion | en |