dc.creator | Bolic, Bojana | |
dc.creator | Mijuskovic, Ana | |
dc.creator | Popovic-Bijelic, Ana | |
dc.creator | Nikolić-Kokić, Aleksandra | |
dc.creator | Spasic, Snezana | |
dc.creator | Blagojević, Duško | |
dc.creator | Spasić, Mihajlo | |
dc.creator | Spasojevic, Ivan | |
dc.date.accessioned | 2016-05-23T11:00:53Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 1089-8611 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/2329 | |
dc.description.abstract | Interactions of hydrogen sulfide (HS-/H2S), a reducing signaling
species, with superoxide dimutases (SOD) are poorly understood. We
applied low-T EPR spectroscopy to examine the effects of HS-/H2S and
superoxide radical anion (O-2(-)) on metallocenters of FeSOD, MnSOD, and
CuZnSOD. HS-/H2S did not affect FeSOD, whereas active centers of MnSOD
and CuZnSOD were open to this agent. Cu2+ was reduced to Cu1+, while
manganese appears to be released from MnSOD active center. Untreated and
O-2(-) treated FeSOD and MnSOD predominantly show 5 d-electron systems,
i.e. Fe3+ and Mn2+. Our study provides new details on the mechanisms of
(patho)physiological effects of HS-/H2S. (C) 2015 Elsevier Inc. All
rights reserved. | en |
dc.description.sponsorship | Ministry for Education, Science and Technological Development of The
Republic of Serbia {[}173014, III41005] | |
dc.language | English | |
dc.rights | restrictedAccess | |
dc.source | Nitric Oxide-Biology and Chemistry | |
dc.subject | Superoxide dismutase | |
dc.subject | Iron | |
dc.subject | Manganese | |
dc.subject | Copper | |
dc.title | Reactions of superoxide dismutases with HS-/H2S and superoxide radical
anion: An in vitro EPR study | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Болиц, Бојана; Николић-Кокић, Aлександра; Мијусковиц, Aна; Поповиц-Бијелиц, Aна; Спасиц, Снезана; Спасић, Михајло Б.; Спасојевиц, Иван; Благојевић, Душко П.; | |
dc.citation.volume | 51 | |
dc.identifier.doi | 10.1016/j.niox.2015.09.008 | |
dc.identifier.scopus | 2-s2.0-84944719548 | |
dc.identifier.wos | 000366065100003 | |
dc.citation.spage | 19 | |
dc.citation.epage | 23 | |
dc.type.version | publishedVersion | en |