TY  - JOUR
AU  - Ferreira, Isabel C. F. R.
AU  - Heleno, Sandrina A.
AU  - Reis, Filipa S.
AU  - Stojković, Dejan
AU  - Queiroz, Maria Joao R. P.
AU  - Helena Vasconcelos, M.
AU  - Soković, Marina
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1948
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3526
AB  - Ganoderma genus comprises one of the most commonly studied species   worldwide, Ganoderma lucidum. However, other Ganoderma species have been   also reported as important sources of bioactive compounds.   Polysaccharides are important contributors to the medicinal properties   reported for Ganoderma species, as demonstrated by the numerous   publications, including reviews, on this matter. Yet, what are the   chemical features of Ganoderma polysaccharides that have bioactivity? In   the present manuscript, the chemical features of Ganoderma   polysaccharides with reported antioxidant, antitumor and antimicrobial   activities (the most studied worldwide) are analyzed in detail. The   composition of sugars (homo- versus hetero-glucans and other   polysaccharides), type of glycosidic linkages, branching patterns, and   linkage to proteins are discussed. Methods for extraction, isolation and   identification are evaluated and, finally, the bioactivity of   polysaccharidic extracts and purified compounds are discussed. The   integration of data allows deduction of structure-activity relationships   and gives clues to the chemical aspects involved in Ganoderma   bioactivity. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Phytochemistry
T1  - Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities
IS  - SI
VL  - 114
DO  - 10.1016/j.phytochem.2014.10.011
SP  - 38
EP  - 55
ER  - 

@article{
author = "Ferreira, Isabel C. F. R. and Heleno, Sandrina A. and Reis, Filipa S. and Stojković, Dejan and Queiroz, Maria Joao R. P. and Helena Vasconcelos, M. and Soković, Marina",
year = "2015",
abstract = "Ganoderma genus comprises one of the most commonly studied species   worldwide, Ganoderma lucidum. However, other Ganoderma species have been   also reported as important sources of bioactive compounds.   Polysaccharides are important contributors to the medicinal properties   reported for Ganoderma species, as demonstrated by the numerous   publications, including reviews, on this matter. Yet, what are the   chemical features of Ganoderma polysaccharides that have bioactivity? In   the present manuscript, the chemical features of Ganoderma   polysaccharides with reported antioxidant, antitumor and antimicrobial   activities (the most studied worldwide) are analyzed in detail. The   composition of sugars (homo- versus hetero-glucans and other   polysaccharides), type of glycosidic linkages, branching patterns, and   linkage to proteins are discussed. Methods for extraction, isolation and   identification are evaluated and, finally, the bioactivity of   polysaccharidic extracts and purified compounds are discussed. The   integration of data allows deduction of structure-activity relationships   and gives clues to the chemical aspects involved in Ganoderma   bioactivity. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Phytochemistry",
title = "Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities",
number = "SI",
volume = "114",
doi = "10.1016/j.phytochem.2014.10.011",
pages = "38-55"
}

Ferreira, I. C. F. R., Heleno, S. A., Reis, F. S., Stojković, D., Queiroz, M. J. R. P., Helena Vasconcelos, M.,& Soković, M.. (2015). Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. in Phytochemistry, 114(SI), 38-55.
https://doi.org/10.1016/j.phytochem.2014.10.011

Ferreira ICFR, Heleno SA, Reis FS, Stojković D, Queiroz MJRP, Helena Vasconcelos M, Soković M. Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. in Phytochemistry. 2015;114(SI):38-55.
doi:10.1016/j.phytochem.2014.10.011 .

Ferreira, Isabel C. F. R., Heleno, Sandrina A., Reis, Filipa S., Stojković, Dejan, Queiroz, Maria Joao R. P., Helena Vasconcelos, M., Soković, Marina, "Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities" in Phytochemistry, 114, no. SI (2015):38-55,
https://doi.org/10.1016/j.phytochem.2014.10.011 . .

TY  - JOUR
AU  - Ferreira, Isabel C. F. R.
AU  - Heleno, Sandrina A.
AU  - Reis, Filipa S.
AU  - Stojković, Dejan
AU  - Queiroz, Maria Joao R. P.
AU  - Helena Vasconcelos, M.
AU  - Soković, Marina
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1948
AB  - Ganoderma genus comprises one of the most commonly studied species
   worldwide, Ganoderma lucidum. However, other Ganoderma species have been
   also reported as important sources of bioactive compounds.
   Polysaccharides are important contributors to the medicinal properties
   reported for Ganoderma species, as demonstrated by the numerous
   publications, including reviews, on this matter. Yet, what are the
   chemical features of Ganoderma polysaccharides that have bioactivity? In
   the present manuscript, the chemical features of Ganoderma
   polysaccharides with reported antioxidant, antitumor and antimicrobial
   activities (the most studied worldwide) are analyzed in detail. The
   composition of sugars (homo- versus hetero-glucans and other
   polysaccharides), type of glycosidic linkages, branching patterns, and
   linkage to proteins are discussed. Methods for extraction, isolation and
   identification are evaluated and, finally, the bioactivity of
   polysaccharidic extracts and purified compounds are discussed. The
   integration of data allows deduction of structure-activity relationships
   and gives clues to the chemical aspects involved in Ganoderma
   bioactivity. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Phytochemistry
T1  - Chemical features of Ganoderma polysaccharides with antioxidant,
 antitumor and antimicrobial activities
IS  - SI
VL  - 114
DO  - 10.1016/j.phytochem.2014.10.011
SP  - 38
EP  - 55
ER  - 

@article{
author = "Ferreira, Isabel C. F. R. and Heleno, Sandrina A. and Reis, Filipa S. and Stojković, Dejan and Queiroz, Maria Joao R. P. and Helena Vasconcelos, M. and Soković, Marina",
year = "2015",
abstract = "Ganoderma genus comprises one of the most commonly studied species
   worldwide, Ganoderma lucidum. However, other Ganoderma species have been
   also reported as important sources of bioactive compounds.
   Polysaccharides are important contributors to the medicinal properties
   reported for Ganoderma species, as demonstrated by the numerous
   publications, including reviews, on this matter. Yet, what are the
   chemical features of Ganoderma polysaccharides that have bioactivity? In
   the present manuscript, the chemical features of Ganoderma
   polysaccharides with reported antioxidant, antitumor and antimicrobial
   activities (the most studied worldwide) are analyzed in detail. The
   composition of sugars (homo- versus hetero-glucans and other
   polysaccharides), type of glycosidic linkages, branching patterns, and
   linkage to proteins are discussed. Methods for extraction, isolation and
   identification are evaluated and, finally, the bioactivity of
   polysaccharidic extracts and purified compounds are discussed. The
   integration of data allows deduction of structure-activity relationships
   and gives clues to the chemical aspects involved in Ganoderma
   bioactivity. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Phytochemistry",
title = "Chemical features of Ganoderma polysaccharides with antioxidant,
 antitumor and antimicrobial activities",
number = "SI",
volume = "114",
doi = "10.1016/j.phytochem.2014.10.011",
pages = "38-55"
}

Ferreira, I. C. F. R., Heleno, S. A., Reis, F. S., Stojković, D., Queiroz, M. J. R. P., Helena Vasconcelos, M.,& Soković, M.. (2015). Chemical features of Ganoderma polysaccharides with antioxidant,
 antitumor and antimicrobial activities. in Phytochemistry, 114(SI), 38-55.
https://doi.org/10.1016/j.phytochem.2014.10.011

Ferreira ICFR, Heleno SA, Reis FS, Stojković D, Queiroz MJRP, Helena Vasconcelos M, Soković M. Chemical features of Ganoderma polysaccharides with antioxidant,
 antitumor and antimicrobial activities. in Phytochemistry. 2015;114(SI):38-55.
doi:10.1016/j.phytochem.2014.10.011 .

Ferreira, Isabel C. F. R., Heleno, Sandrina A., Reis, Filipa S., Stojković, Dejan, Queiroz, Maria Joao R. P., Helena Vasconcelos, M., Soković, Marina, "Chemical features of Ganoderma polysaccharides with antioxidant,
 antitumor and antimicrobial activities" in Phytochemistry, 114, no. SI (2015):38-55,
https://doi.org/10.1016/j.phytochem.2014.10.011 . .

TY  - JOUR
AU  - Heleno, Sandrina A.
AU  - Ferreira, Isabel C. F. R.
AU  - Ćirić, Ana
AU  - Glamočlija, Jasmina
AU  - Martins, Anabela
AU  - Queiroz, Maria Joao R. P.
AU  - Soković, Marina
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2149
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3611
AB  - Despite the available data regarding antimicrobial activity of phenolic   acids, studies dealing with the effects of their metabolites or   derivatives are scarce. Therefore, the antimicrobial and demelanizing   activities of Coprinopsis atramentaria extract, its organic acids, and   methylated and glucuronated derivatives were evaluated. The antifungal   activity was stronger than the antibacterial effects. In general,   individual compounds (mostly organic acids) exhibited higher activity   than the extract and even higher than the standards used in the assays.   Methylated derivatives presented the highest demelanizing activity   toward Aspergillus niger, A. fumigatus and Penicillium verrucosum var.   cyclopium. The inclusion of methyl groups in the parental compound   (CoAM1, CoAM2 and CoAM3) strongly increased antibacterial and antifungal   activities of CoA, while the inclusion of acetyl groups (CoAGP)   increased the antifungal activity but the antibacterial properties were   maintained. For HA and CA, the inclusion of methyl groups (HAM1, HAM2,   HAM3 and CAM) increased the demelanizing activity, but decreased the   antimicrobial properties. The present work contributes to the knowledge   of the mechanisms involved in the antimicrobial properties of organic   acids namely, phenolic acids, usually present in mushrooms. Organic   acids, and methylated and glucuronated derivatives could be used as   antimicrobial agents.
T2  - Food & Function
T1  - Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents
IS  - 10
VL  - 5
DO  - 10.1039/c4fo00490f
SP  - 2521
EP  - 2528
ER  - 

@article{
author = "Heleno, Sandrina A. and Ferreira, Isabel C. F. R. and Ćirić, Ana and Glamočlija, Jasmina and Martins, Anabela and Queiroz, Maria Joao R. P. and Soković, Marina",
year = "2014",
abstract = "Despite the available data regarding antimicrobial activity of phenolic   acids, studies dealing with the effects of their metabolites or   derivatives are scarce. Therefore, the antimicrobial and demelanizing   activities of Coprinopsis atramentaria extract, its organic acids, and   methylated and glucuronated derivatives were evaluated. The antifungal   activity was stronger than the antibacterial effects. In general,   individual compounds (mostly organic acids) exhibited higher activity   than the extract and even higher than the standards used in the assays.   Methylated derivatives presented the highest demelanizing activity   toward Aspergillus niger, A. fumigatus and Penicillium verrucosum var.   cyclopium. The inclusion of methyl groups in the parental compound   (CoAM1, CoAM2 and CoAM3) strongly increased antibacterial and antifungal   activities of CoA, while the inclusion of acetyl groups (CoAGP)   increased the antifungal activity but the antibacterial properties were   maintained. For HA and CA, the inclusion of methyl groups (HAM1, HAM2,   HAM3 and CAM) increased the demelanizing activity, but decreased the   antimicrobial properties. The present work contributes to the knowledge   of the mechanisms involved in the antimicrobial properties of organic   acids namely, phenolic acids, usually present in mushrooms. Organic   acids, and methylated and glucuronated derivatives could be used as   antimicrobial agents.",
journal = "Food & Function",
title = "Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents",
number = "10",
volume = "5",
doi = "10.1039/c4fo00490f",
pages = "2521-2528"
}

Heleno, S. A., Ferreira, I. C. F. R., Ćirić, A., Glamočlija, J., Martins, A., Queiroz, M. J. R. P.,& Soković, M.. (2014). Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents. in Food & Function, 5(10), 2521-2528.
https://doi.org/10.1039/c4fo00490f

Heleno SA, Ferreira ICFR, Ćirić A, Glamočlija J, Martins A, Queiroz MJRP, Soković M. Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents. in Food & Function. 2014;5(10):2521-2528.
doi:10.1039/c4fo00490f .

Heleno, Sandrina A., Ferreira, Isabel C. F. R., Ćirić, Ana, Glamočlija, Jasmina, Martins, Anabela, Queiroz, Maria Joao R. P., Soković, Marina, "Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents" in Food & Function, 5, no. 10 (2014):2521-2528,
https://doi.org/10.1039/c4fo00490f . .

TY  - JOUR
AU  - Heleno, Sandrina A.
AU  - Ferreira, Isabel C. F. R.
AU  - Ćirić, Ana
AU  - Glamočlija, Jasmina
AU  - Martins, Anabela
AU  - Queiroz, Maria Joao R. P.
AU  - Soković, Marina
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2149
AB  - Despite the available data regarding antimicrobial activity of phenolic
   acids, studies dealing with the effects of their metabolites or
   derivatives are scarce. Therefore, the antimicrobial and demelanizing
   activities of Coprinopsis atramentaria extract, its organic acids, and
   methylated and glucuronated derivatives were evaluated. The antifungal
   activity was stronger than the antibacterial effects. In general,
   individual compounds (mostly organic acids) exhibited higher activity
   than the extract and even higher than the standards used in the assays.
   Methylated derivatives presented the highest demelanizing activity
   toward Aspergillus niger, A. fumigatus and Penicillium verrucosum var.
   cyclopium. The inclusion of methyl groups in the parental compound
   (CoAM1, CoAM2 and CoAM3) strongly increased antibacterial and antifungal
   activities of CoA, while the inclusion of acetyl groups (CoAGP)
   increased the antifungal activity but the antibacterial properties were
   maintained. For HA and CA, the inclusion of methyl groups (HAM1, HAM2,
   HAM3 and CAM) increased the demelanizing activity, but decreased the
   antimicrobial properties. The present work contributes to the knowledge
   of the mechanisms involved in the antimicrobial properties of organic
   acids namely, phenolic acids, usually present in mushrooms. Organic
   acids, and methylated and glucuronated derivatives could be used as
   antimicrobial agents.
T2  - Food & Function
T1  - Coprinopsis atramentaria extract, its organic acids, and synthesized
 glucuronated and methylated derivatives as antibacterial and antifungal
 agents
IS  - 10
VL  - 5
DO  - 10.1039/c4fo00490f
SP  - 2521
EP  - 2528
ER  - 

@article{
author = "Heleno, Sandrina A. and Ferreira, Isabel C. F. R. and Ćirić, Ana and Glamočlija, Jasmina and Martins, Anabela and Queiroz, Maria Joao R. P. and Soković, Marina",
year = "2014",
abstract = "Despite the available data regarding antimicrobial activity of phenolic
   acids, studies dealing with the effects of their metabolites or
   derivatives are scarce. Therefore, the antimicrobial and demelanizing
   activities of Coprinopsis atramentaria extract, its organic acids, and
   methylated and glucuronated derivatives were evaluated. The antifungal
   activity was stronger than the antibacterial effects. In general,
   individual compounds (mostly organic acids) exhibited higher activity
   than the extract and even higher than the standards used in the assays.
   Methylated derivatives presented the highest demelanizing activity
   toward Aspergillus niger, A. fumigatus and Penicillium verrucosum var.
   cyclopium. The inclusion of methyl groups in the parental compound
   (CoAM1, CoAM2 and CoAM3) strongly increased antibacterial and antifungal
   activities of CoA, while the inclusion of acetyl groups (CoAGP)
   increased the antifungal activity but the antibacterial properties were
   maintained. For HA and CA, the inclusion of methyl groups (HAM1, HAM2,
   HAM3 and CAM) increased the demelanizing activity, but decreased the
   antimicrobial properties. The present work contributes to the knowledge
   of the mechanisms involved in the antimicrobial properties of organic
   acids namely, phenolic acids, usually present in mushrooms. Organic
   acids, and methylated and glucuronated derivatives could be used as
   antimicrobial agents.",
journal = "Food & Function",
title = "Coprinopsis atramentaria extract, its organic acids, and synthesized
 glucuronated and methylated derivatives as antibacterial and antifungal
 agents",
number = "10",
volume = "5",
doi = "10.1039/c4fo00490f",
pages = "2521-2528"
}

Heleno, S. A., Ferreira, I. C. F. R., Ćirić, A., Glamočlija, J., Martins, A., Queiroz, M. J. R. P.,& Soković, M.. (2014). Coprinopsis atramentaria extract, its organic acids, and synthesized
 glucuronated and methylated derivatives as antibacterial and antifungal
 agents. in Food & Function, 5(10), 2521-2528.
https://doi.org/10.1039/c4fo00490f

Heleno SA, Ferreira ICFR, Ćirić A, Glamočlija J, Martins A, Queiroz MJRP, Soković M. Coprinopsis atramentaria extract, its organic acids, and synthesized
 glucuronated and methylated derivatives as antibacterial and antifungal
 agents. in Food & Function. 2014;5(10):2521-2528.
doi:10.1039/c4fo00490f .

Heleno, Sandrina A., Ferreira, Isabel C. F. R., Ćirić, Ana, Glamočlija, Jasmina, Martins, Anabela, Queiroz, Maria Joao R. P., Soković, Marina, "Coprinopsis atramentaria extract, its organic acids, and synthesized
 glucuronated and methylated derivatives as antibacterial and antifungal
 agents" in Food & Function, 5, no. 10 (2014):2521-2528,
https://doi.org/10.1039/c4fo00490f . .