TY  - JOUR
AU  - Jadranin, Milka
AU  - Savić, Danica
AU  - Lupšić, Ema
AU  - Podolski-Renić, Ana
AU  - Pešić, Milica
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
AU  - Krstić, Gordana
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6557
AB  - Euphorbia seguieriana ssp. seguieriana Necker (ES) and Euphorbia cyparissias (EC) with a habitat in the Deliblato Sands were the subject of this examination. The latexes of these so far insufficiently investigated species of the Euphorbia genus are used in traditional medicine for the treatment of wounds and warts on the skin. To determine their chemical composition, non-targeted screening of the latexes' chloroform extracts was performed using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry employing an electrospray ionization source (LC-ESI QTOF MS). The analysis of the obtained results showed that the latexes of ES and EC represent rich sources of diterpenes, tentatively identified as jatrophanes, ingenanes, tiglianes, myrsinanes, premyrsinanes, and others. Examination of the anticancer activity of the ES and EC latex extracts showed that both extracts significantly inhibited the growth of the non-small cell lung carcinoma NCI-H460 and glioblastoma U87 cell lines as well as of their corresponding multi-drug resistant (MDR) cell lines, NCI-H460/R and U87-TxR. The obtained results also revealed that the ES and EC extracts inhibited the function of P-glycoprotein (P-gp) in MDR cancer cells, whose overexpression is one of the main mechanisms underlying MDR.
PB  - Basel: MDPI
T2  - Plants
T1  - LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity
IS  - 24
VL  - 12
DO  - 10.3390/plants12244181
SP  - 4181
ER  - 

@article{
author = "Jadranin, Milka and Savić, Danica and Lupšić, Ema and Podolski-Renić, Ana and Pešić, Milica and Tešević, Vele and Milosavljević, Slobodan and Krstić, Gordana",
year = "2023",
abstract = "Euphorbia seguieriana ssp. seguieriana Necker (ES) and Euphorbia cyparissias (EC) with a habitat in the Deliblato Sands were the subject of this examination. The latexes of these so far insufficiently investigated species of the Euphorbia genus are used in traditional medicine for the treatment of wounds and warts on the skin. To determine their chemical composition, non-targeted screening of the latexes' chloroform extracts was performed using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry employing an electrospray ionization source (LC-ESI QTOF MS). The analysis of the obtained results showed that the latexes of ES and EC represent rich sources of diterpenes, tentatively identified as jatrophanes, ingenanes, tiglianes, myrsinanes, premyrsinanes, and others. Examination of the anticancer activity of the ES and EC latex extracts showed that both extracts significantly inhibited the growth of the non-small cell lung carcinoma NCI-H460 and glioblastoma U87 cell lines as well as of their corresponding multi-drug resistant (MDR) cell lines, NCI-H460/R and U87-TxR. The obtained results also revealed that the ES and EC extracts inhibited the function of P-glycoprotein (P-gp) in MDR cancer cells, whose overexpression is one of the main mechanisms underlying MDR.",
publisher = "Basel: MDPI",
journal = "Plants",
title = "LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity",
number = "24",
volume = "12",
doi = "10.3390/plants12244181",
pages = "4181"
}

Jadranin, M., Savić, D., Lupšić, E., Podolski-Renić, A., Pešić, M., Tešević, V., Milosavljević, S.,& Krstić, G.. (2023). LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity. in Plants
Basel: MDPI., 12(24), 4181.
https://doi.org/10.3390/plants12244181

Jadranin M, Savić D, Lupšić E, Podolski-Renić A, Pešić M, Tešević V, Milosavljević S, Krstić G. LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity. in Plants. 2023;12(24):4181.
doi:10.3390/plants12244181 .

Jadranin, Milka, Savić, Danica, Lupšić, Ema, Podolski-Renić, Ana, Pešić, Milica, Tešević, Vele, Milosavljević, Slobodan, Krstić, Gordana, "LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity" in Plants, 12, no. 24 (2023):4181,
https://doi.org/10.3390/plants12244181 . .

TY  - CONF
AU  - Krstić, Gordana
AU  - Jadranin, Milka
AU  - Jovanović Stojanov, Sofija
AU  - Pešić, Milica
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6594
AB  - In this research, from two species, E. palustris and E. lucida, four ingenane derivatives were isolated. Their anticancer effects were evaluated in the human melanoma – 518A2 cell line and compared with the effects of ingenolmebutate. Selectivity towards human melanoma cells was determined using normal human keratinocytes – HaCaT.
PB  - Skopje: Macedonian Pharmaceutical Association
C3  - 11th Conference on Medicinal and Aromatic Plants of Southeast European Countries 2022: CMAPSEEC 2022; 2022 Oct 6-10; Ohrid, Republic of North Macedonia
T1  - Anti-melanoma effects of ingenanes isolated from Euphorbia species
DO  - 10.33320/maced.pharm.bull.2022.68.04.006
SP  - 23
EP  - 24
ER  - 

@conference{
author = "Krstić, Gordana and Jadranin, Milka and Jovanović Stojanov, Sofija and Pešić, Milica and Tešević, Vele and Milosavljević, Slobodan",
year = "2022",
abstract = "In this research, from two species, E. palustris and E. lucida, four ingenane derivatives were isolated. Their anticancer effects were evaluated in the human melanoma – 518A2 cell line and compared with the effects of ingenolmebutate. Selectivity towards human melanoma cells was determined using normal human keratinocytes – HaCaT.",
publisher = "Skopje: Macedonian Pharmaceutical Association",
journal = "11th Conference on Medicinal and Aromatic Plants of Southeast European Countries 2022: CMAPSEEC 2022; 2022 Oct 6-10; Ohrid, Republic of North Macedonia",
title = "Anti-melanoma effects of ingenanes isolated from Euphorbia species",
doi = "10.33320/maced.pharm.bull.2022.68.04.006",
pages = "23-24"
}

Krstić, G., Jadranin, M., Jovanović Stojanov, S., Pešić, M., Tešević, V.,& Milosavljević, S.. (2022). Anti-melanoma effects of ingenanes isolated from Euphorbia species. in 11th Conference on Medicinal and Aromatic Plants of Southeast European Countries 2022: CMAPSEEC 2022; 2022 Oct 6-10; Ohrid, Republic of North Macedonia
Skopje: Macedonian Pharmaceutical Association., 23-24.
https://doi.org/10.33320/maced.pharm.bull.2022.68.04.006

Krstić G, Jadranin M, Jovanović Stojanov S, Pešić M, Tešević V, Milosavljević S. Anti-melanoma effects of ingenanes isolated from Euphorbia species. in 11th Conference on Medicinal and Aromatic Plants of Southeast European Countries 2022: CMAPSEEC 2022; 2022 Oct 6-10; Ohrid, Republic of North Macedonia. 2022;:23-24.
doi:10.33320/maced.pharm.bull.2022.68.04.006 .

Krstić, Gordana, Jadranin, Milka, Jovanović Stojanov, Sofija, Pešić, Milica, Tešević, Vele, Milosavljević, Slobodan, "Anti-melanoma effects of ingenanes isolated from Euphorbia species" in 11th Conference on Medicinal and Aromatic Plants of Southeast European Countries 2022: CMAPSEEC 2022; 2022 Oct 6-10; Ohrid, Republic of North Macedonia (2022):23-24,
https://doi.org/10.33320/maced.pharm.bull.2022.68.04.006 . .

TY  - JOUR
AU  - Novaković, Miroslav
AU  - Nikodinović-Runić, Jasmina
AU  - Veselinović, Jovana
AU  - Ilić-Tomić, Tatjana
AU  - Vidaković, Vera
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
PY  - 2017
UR  - http://pubs.acs.org/doi/abs/10.1021/acs.jnatprod.6b00805
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2765
AB  - Seven derivatives of pentacyclic triterpene acids (1-7) were isolated from the bark of Alnus viridis ssp. viridis using a combination of column chromatography and semipreparative HPLC. Compounds 1-3, 6, and 7 were determined to be new after spectroscopic data interpretation and were assigned as 27-hydroxyalphitolic acid derivatives (1-3), a 27-hydroxybetulinic acid derivative (6), and a 3-epi-maslinic acid derivative (7), respectively. Pentacyclic triterpenoids with a C-27 hydroxymethyl group have been found in species of the genus Alnus for the first time. These compounds were subjected to cytotoxicity testing against a number of cancer cell lines. Also, selected pentacyclic triterpenoids were selected as potential inhibitors of topoisomerases I and IIα for an in silico investigation.
T2  - Journal of Natural Products
T1  - Bioactive Pentacyclic Triterpene Ester Derivatives from Alnus viridis ssp. viridis Bark
IS  - 5
VL  - 80
DO  - 10.1021/acs.jnatprod.6b00805
SP  - 1255
EP  - 1263
ER  - 

@article{
author = "Novaković, Miroslav and Nikodinović-Runić, Jasmina and Veselinović, Jovana and Ilić-Tomić, Tatjana and Vidaković, Vera and Tešević, Vele and Milosavljević, Slobodan",
year = "2017",
abstract = "Seven derivatives of pentacyclic triterpene acids (1-7) were isolated from the bark of Alnus viridis ssp. viridis using a combination of column chromatography and semipreparative HPLC. Compounds 1-3, 6, and 7 were determined to be new after spectroscopic data interpretation and were assigned as 27-hydroxyalphitolic acid derivatives (1-3), a 27-hydroxybetulinic acid derivative (6), and a 3-epi-maslinic acid derivative (7), respectively. Pentacyclic triterpenoids with a C-27 hydroxymethyl group have been found in species of the genus Alnus for the first time. These compounds were subjected to cytotoxicity testing against a number of cancer cell lines. Also, selected pentacyclic triterpenoids were selected as potential inhibitors of topoisomerases I and IIα for an in silico investigation.",
journal = "Journal of Natural Products",
title = "Bioactive Pentacyclic Triterpene Ester Derivatives from Alnus viridis ssp. viridis Bark",
number = "5",
volume = "80",
doi = "10.1021/acs.jnatprod.6b00805",
pages = "1255-1263"
}

Novaković, M., Nikodinović-Runić, J., Veselinović, J., Ilić-Tomić, T., Vidaković, V., Tešević, V.,& Milosavljević, S.. (2017). Bioactive Pentacyclic Triterpene Ester Derivatives from Alnus viridis ssp. viridis Bark. in Journal of Natural Products, 80(5), 1255-1263.
https://doi.org/10.1021/acs.jnatprod.6b00805

Novaković M, Nikodinović-Runić J, Veselinović J, Ilić-Tomić T, Vidaković V, Tešević V, Milosavljević S. Bioactive Pentacyclic Triterpene Ester Derivatives from Alnus viridis ssp. viridis Bark. in Journal of Natural Products. 2017;80(5):1255-1263.
doi:10.1021/acs.jnatprod.6b00805 .

Novaković, Miroslav, Nikodinović-Runić, Jasmina, Veselinović, Jovana, Ilić-Tomić, Tatjana, Vidaković, Vera, Tešević, Vele, Milosavljević, Slobodan, "Bioactive Pentacyclic Triterpene Ester Derivatives from Alnus viridis ssp. viridis Bark" in Journal of Natural Products, 80, no. 5 (2017):1255-1263,
https://doi.org/10.1021/acs.jnatprod.6b00805 . .

TY  - JOUR
AU  - Petrović, Jovana
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
AU  - Vučković, Ivan
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
AU  - Stešević, Danijela
PY  - 2011
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3466
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1934578X1100600227
AB  - The essential oil isolated from Seseli montanum L. subsp. tommasinii Reich. f. was analyzed by GC/MS and the most abundant components
were β-pinene (30.2%), germacrene D (10.1%), sabinene (8.0%), α-pinene (7.2%) and limonene (6.6%). The antimicrobial effect of the
essential oil was evaluated against four bacterial and four fungal species among which were food contaminants, spoilage fungi, and plant,
fungal and animal pathogens. The oil possessed moderate to strong antimicrobial activity.
T2  - Natural Product Communications
T1  - Composition and Antimicrobial Activity of Seseli montanum subsp. tommasinii Essential Oil
IS  - 2
VL  - 6
SP  - 263
EP  - 266
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_3466
ER  - 

@article{
author = "Petrović, Jovana and Glamočlija, Jasmina and Soković, Marina and Vučković, Ivan and Tešević, Vele and Milosavljević, Slobodan and Stešević, Danijela",
year = "2011",
abstract = "The essential oil isolated from Seseli montanum L. subsp. tommasinii Reich. f. was analyzed by GC/MS and the most abundant components
were β-pinene (30.2%), germacrene D (10.1%), sabinene (8.0%), α-pinene (7.2%) and limonene (6.6%). The antimicrobial effect of the
essential oil was evaluated against four bacterial and four fungal species among which were food contaminants, spoilage fungi, and plant,
fungal and animal pathogens. The oil possessed moderate to strong antimicrobial activity.",
journal = "Natural Product Communications",
title = "Composition and Antimicrobial Activity of Seseli montanum subsp. tommasinii Essential Oil",
number = "2",
volume = "6",
pages = "263-266",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_3466"
}

Petrović, J., Glamočlija, J., Soković, M., Vučković, I., Tešević, V., Milosavljević, S.,& Stešević, D.. (2011). Composition and Antimicrobial Activity of Seseli montanum subsp. tommasinii Essential Oil. in Natural Product Communications, 6(2), 263-266.
https://hdl.handle.net/21.15107/rcub_ibiss_3466

Petrović J, Glamočlija J, Soković M, Vučković I, Tešević V, Milosavljević S, Stešević D. Composition and Antimicrobial Activity of Seseli montanum subsp. tommasinii Essential Oil. in Natural Product Communications. 2011;6(2):263-266.
https://hdl.handle.net/21.15107/rcub_ibiss_3466 .

Petrović, Jovana, Glamočlija, Jasmina, Soković, Marina, Vučković, Ivan, Tešević, Vele, Milosavljević, Slobodan, Stešević, Danijela, "Composition and Antimicrobial Activity of Seseli montanum subsp. tommasinii Essential Oil" in Natural Product Communications, 6, no. 2 (2011):263-266,
https://hdl.handle.net/21.15107/rcub_ibiss_3466 .

TY  - JOUR
AU  - Soković, Marina
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
AU  - Vajs, Vlatka
AU  - Đorđević, Iris
AU  - Lavadinović, Vera
AU  - Novaković, Miroslav
PY  - 2009
PY  - 2009
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/559
AB  - The chemical composition of the essential oil of fresh young needles with twigs of Douglas fir (Pseudosuga menziesii Mirb. Franco) obtained by hydrodistillation were analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Ten compounds, accounting for 94.26 % of the oil, were identified. The main compounds found were bornyl acetate (34.65 %), camphene (29.82 %), α-pinene (11.65 %) and santene (5.45 %). The antifungal activity of the essential oil was tested against various fungal species. The minimum inhibitory concentration of Douglas fir essential oil ranged from 1.5 to 4 μg mL-1. The fungi most sensitive to the tested oil were Phomopsis helianthi, while Penicillium species, along with Microsporum canis, were the most resistant. Compared to the commercial fungicidal agent bifonazole, the studied essential oil demonstrated higher antifungal activity.
AB  - Hemijski sastav etarskog ulja mladih iglica sa grančicama duglazije (Pseudosuga menziesii Mirb. Franco) dobijenog destilacijom vodenom parom, analiziran je gasnom hromatografijom (GC) i kombinacijom gasne hromatografije i masene spektrometrije (GC/MS). Identifikovano je deset jedinjenja ukupne zastupljenosti 94,26 %. Kao glavne komponente su nađeni: bornil-acetat (34,65 %), kamfen (29,82 %), α-pinen (11,65 %) i santen (5,45 %). Pored toga, etarsko ulje je testirano na antifungalnu aktivnost. Etarsko ulje pokazuje mnogo bolju antifugalnu akivnost od komercijalnog fungicidnog agensa bifonazola. Minimalna inhibitorna koncentracija etarskog ulja duglazije je u opsegu od 0,6 do 1,4 μL mL-1. Najosetljiviji na testirano ulje je bio soj Phomopsis helianthi, dok sojevi Penicillium i Microsporum canis pokazuju najveću rezistentnost.
T2  - Journal of the Serbian Chemical Society
T1  - Hemijski sastav i antifungalna aktivnost etarskog ulja daglasove jele (Pseudosuga menziesii mirb. Franco) iz Srbije
T1  - Chemical composition and antifungal activity of the essential oil of Douglas fir (Pseudosuga menziesii mirb. Franco) from Serbia
IS  - 10
VL  - 74
SP  - 1035
EP  - 1040
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_559
ER  - 

@article{
author = "Soković, Marina and Tešević, Vele and Milosavljević, Slobodan and Vajs, Vlatka and Đorđević, Iris and Lavadinović, Vera and Novaković, Miroslav",
year = "2009, 2009",
abstract = "The chemical composition of the essential oil of fresh young needles with twigs of Douglas fir (Pseudosuga menziesii Mirb. Franco) obtained by hydrodistillation were analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Ten compounds, accounting for 94.26 % of the oil, were identified. The main compounds found were bornyl acetate (34.65 %), camphene (29.82 %), α-pinene (11.65 %) and santene (5.45 %). The antifungal activity of the essential oil was tested against various fungal species. The minimum inhibitory concentration of Douglas fir essential oil ranged from 1.5 to 4 μg mL-1. The fungi most sensitive to the tested oil were Phomopsis helianthi, while Penicillium species, along with Microsporum canis, were the most resistant. Compared to the commercial fungicidal agent bifonazole, the studied essential oil demonstrated higher antifungal activity., Hemijski sastav etarskog ulja mladih iglica sa grančicama duglazije (Pseudosuga menziesii Mirb. Franco) dobijenog destilacijom vodenom parom, analiziran je gasnom hromatografijom (GC) i kombinacijom gasne hromatografije i masene spektrometrije (GC/MS). Identifikovano je deset jedinjenja ukupne zastupljenosti 94,26 %. Kao glavne komponente su nađeni: bornil-acetat (34,65 %), kamfen (29,82 %), α-pinen (11,65 %) i santen (5,45 %). Pored toga, etarsko ulje je testirano na antifungalnu aktivnost. Etarsko ulje pokazuje mnogo bolju antifugalnu akivnost od komercijalnog fungicidnog agensa bifonazola. Minimalna inhibitorna koncentracija etarskog ulja duglazije je u opsegu od 0,6 do 1,4 μL mL-1. Najosetljiviji na testirano ulje je bio soj Phomopsis helianthi, dok sojevi Penicillium i Microsporum canis pokazuju najveću rezistentnost.",
journal = "Journal of the Serbian Chemical Society",
title = "Hemijski sastav i antifungalna aktivnost etarskog ulja daglasove jele (Pseudosuga menziesii mirb. Franco) iz Srbije, Chemical composition and antifungal activity of the essential oil of Douglas fir (Pseudosuga menziesii mirb. Franco) from Serbia",
number = "10",
volume = "74",
pages = "1035-1040",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_559"
}

Soković, M., Tešević, V., Milosavljević, S., Vajs, V., Đorđević, I., Lavadinović, V.,& Novaković, M.. (2009). Hemijski sastav i antifungalna aktivnost etarskog ulja daglasove jele (Pseudosuga menziesii mirb. Franco) iz Srbije. in Journal of the Serbian Chemical Society, 74(10), 1035-1040.
https://hdl.handle.net/21.15107/rcub_ibiss_559

Soković M, Tešević V, Milosavljević S, Vajs V, Đorđević I, Lavadinović V, Novaković M. Hemijski sastav i antifungalna aktivnost etarskog ulja daglasove jele (Pseudosuga menziesii mirb. Franco) iz Srbije. in Journal of the Serbian Chemical Society. 2009;74(10):1035-1040.
https://hdl.handle.net/21.15107/rcub_ibiss_559 .

Soković, Marina, Tešević, Vele, Milosavljević, Slobodan, Vajs, Vlatka, Đorđević, Iris, Lavadinović, Vera, Novaković, Miroslav, "Hemijski sastav i antifungalna aktivnost etarskog ulja daglasove jele (Pseudosuga menziesii mirb. Franco) iz Srbije" in Journal of the Serbian Chemical Society, 74, no. 10 (2009):1035-1040,
https://hdl.handle.net/21.15107/rcub_ibiss_559 .

TY  - JOUR
AU  - Novaković, Miroslav
AU  - Soković, Marina
AU  - Vučković, Ivan
AU  - Janaćković, Peđa
AU  - Filipović, Anka
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
PY  - 2007
PY  - 2007
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/555
AB  - Essential oils from leaves with young branches of Cotinus coggygria Scop. from two localities in Serbia (Deliblatska peščara and Zemun), obtained by hydrodistillation, were analyzed by GC-MS. Thirty-one component were identified from both oils and among them monoterpenic hydrocarbons were the dominant class (87.4 and 93.1 %). The dominant constituent in both essential oils was limonene (47.0 and 39.2 %). Both oils were also tested for antibacterial and antifungal activities. In comparison to streptomycin, both oils showed slightly higher activity (against most Gram-positive bacteria) in the disc diffusion method and slightly lower activity when the microdilution method was employed. They also exhibited antifungal potential higher than that of the commercial fungicide bifonazole.
AB  - Primenom GC-MS metode identifikovana je ukupno 31 komponenta u oba etarska ulja izolovana destilacijom vodenom parom iz lišća i mladih grančica biljne vrste Cotinus coggygria Scop. sa dva lokaliteta u Srbiji (Deliblatska peščara i Zemun). Takođe je ispitana antibakterijska i antifungalna aktivnost oba uzorka. U oba ulja najzastupljeniji su bili monoterpenski ugljovodonici (87,4 i 93,1 %), među kojima je dominantna komponenta limonen (47,0 i 39,2 %). Antibakterijska aktivnost je određena difuzionom i mikrodilucionom metodom, a antifungalna aktivnost modifikovanom mikrodilucionom metodom. Prema dufuzionoj metodi, oba ulja su pokazala nešto bolje antibakterijsko dejstvo (prvenstveno na gram-pozitivne bakterije) nego streptomicin, dok je na osnovu mikrodilucione metode njihova aktivnost bila nešto slabija. U poređenju sa bifonazolom, oba testirana ulja su pokazala nešto bolje antifungalno dejstvo.
T2  - Journal of the Serbian Chemical Society
T1  - Hemijski sastav, antibakterijska i antifungalna aktivnost etarskih ulja biljne vrste Cotinus coggygria iz Srbije
T1  - Chemical composition, antibacterial and antifungal activity of the essential oils of Cotinus coggygria from Serbia
IS  - 11
VL  - 72
SP  - 1045
EP  - 1051
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_555
ER  - 

@article{
author = "Novaković, Miroslav and Soković, Marina and Vučković, Ivan and Janaćković, Peđa and Filipović, Anka and Tešević, Vele and Milosavljević, Slobodan",
year = "2007, 2007",
abstract = "Essential oils from leaves with young branches of Cotinus coggygria Scop. from two localities in Serbia (Deliblatska peščara and Zemun), obtained by hydrodistillation, were analyzed by GC-MS. Thirty-one component were identified from both oils and among them monoterpenic hydrocarbons were the dominant class (87.4 and 93.1 %). The dominant constituent in both essential oils was limonene (47.0 and 39.2 %). Both oils were also tested for antibacterial and antifungal activities. In comparison to streptomycin, both oils showed slightly higher activity (against most Gram-positive bacteria) in the disc diffusion method and slightly lower activity when the microdilution method was employed. They also exhibited antifungal potential higher than that of the commercial fungicide bifonazole., Primenom GC-MS metode identifikovana je ukupno 31 komponenta u oba etarska ulja izolovana destilacijom vodenom parom iz lišća i mladih grančica biljne vrste Cotinus coggygria Scop. sa dva lokaliteta u Srbiji (Deliblatska peščara i Zemun). Takođe je ispitana antibakterijska i antifungalna aktivnost oba uzorka. U oba ulja najzastupljeniji su bili monoterpenski ugljovodonici (87,4 i 93,1 %), među kojima je dominantna komponenta limonen (47,0 i 39,2 %). Antibakterijska aktivnost je određena difuzionom i mikrodilucionom metodom, a antifungalna aktivnost modifikovanom mikrodilucionom metodom. Prema dufuzionoj metodi, oba ulja su pokazala nešto bolje antibakterijsko dejstvo (prvenstveno na gram-pozitivne bakterije) nego streptomicin, dok je na osnovu mikrodilucione metode njihova aktivnost bila nešto slabija. U poređenju sa bifonazolom, oba testirana ulja su pokazala nešto bolje antifungalno dejstvo.",
journal = "Journal of the Serbian Chemical Society",
title = "Hemijski sastav, antibakterijska i antifungalna aktivnost etarskih ulja biljne vrste Cotinus coggygria iz Srbije, Chemical composition, antibacterial and antifungal activity of the essential oils of Cotinus coggygria from Serbia",
number = "11",
volume = "72",
pages = "1045-1051",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_555"
}

Novaković, M., Soković, M., Vučković, I., Janaćković, P., Filipović, A., Tešević, V.,& Milosavljević, S.. (2007). Hemijski sastav, antibakterijska i antifungalna aktivnost etarskih ulja biljne vrste Cotinus coggygria iz Srbije. in Journal of the Serbian Chemical Society, 72(11), 1045-1051.
https://hdl.handle.net/21.15107/rcub_ibiss_555

Novaković M, Soković M, Vučković I, Janaćković P, Filipović A, Tešević V, Milosavljević S. Hemijski sastav, antibakterijska i antifungalna aktivnost etarskih ulja biljne vrste Cotinus coggygria iz Srbije. in Journal of the Serbian Chemical Society. 2007;72(11):1045-1051.
https://hdl.handle.net/21.15107/rcub_ibiss_555 .

Novaković, Miroslav, Soković, Marina, Vučković, Ivan, Janaćković, Peđa, Filipović, Anka, Tešević, Vele, Milosavljević, Slobodan, "Hemijski sastav, antibakterijska i antifungalna aktivnost etarskih ulja biljne vrste Cotinus coggygria iz Srbije" in Journal of the Serbian Chemical Society, 72, no. 11 (2007):1045-1051,
https://hdl.handle.net/21.15107/rcub_ibiss_555 .

TY  - JOUR
AU  - Vajs, Vlatka
AU  - Soković, Marina
AU  - Trifunović, Snežana
AU  - Janaćković, Peđa T.
AU  - Milosavljević, Slobodan
AU  - Tešević, Vele
PY  - 2004
PY  - 2004
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/547
AB  - Five tetrahydrofuran sesquiterpenes, so-called davanones, and coumarin umbelliferone isolated from Artemisia lobelii All. var. canescens (DC) Briqu, were tested for antifungal activity. All the compounds inhibited the growth of the applied fungi. The overall activity of one of them 2-hydroxy-2,6,10-trimethyl-7,10-epoxydodeca- 3,11-dien-5-on, was comparable to that of the antibiotic bifonazole.
AB  - Pet tetrahidrofuranskih terpenoida davanonskog tipa i kumarin umbeliferon koji su prethodno izolovani iz biljne vrste Aretemisia lobelii var. conescens ispitivani su na antifungalnu aktivnost. Sva testirana jedinjenja inhibiraju rast primenjenih kultura gljiva. Najveću aktivnost, koja se može meriti sa aktivnošću komercijalnog antibiotika bifonazola, pokazuje 2-hidroksi-2,6,10-trimetil-7,10-epoksidodeka-3,11-dien-5-on.
T2  - Journal of the Serbian Chemical Society
T1  - Antifungalna aktivnost terpenoida davanonskog tipa izolovanih iz Artemisia lobelii Var. canescens
T1  - Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelli var. conescens
IS  - 11
VL  - 69
SP  - 969
EP  - 972
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_547
ER  - 

@article{
author = "Vajs, Vlatka and Soković, Marina and Trifunović, Snežana and Janaćković, Peđa T. and Milosavljević, Slobodan and Tešević, Vele",
year = "2004, 2004",
abstract = "Five tetrahydrofuran sesquiterpenes, so-called davanones, and coumarin umbelliferone isolated from Artemisia lobelii All. var. canescens (DC) Briqu, were tested for antifungal activity. All the compounds inhibited the growth of the applied fungi. The overall activity of one of them 2-hydroxy-2,6,10-trimethyl-7,10-epoxydodeca- 3,11-dien-5-on, was comparable to that of the antibiotic bifonazole., Pet tetrahidrofuranskih terpenoida davanonskog tipa i kumarin umbeliferon koji su prethodno izolovani iz biljne vrste Aretemisia lobelii var. conescens ispitivani su na antifungalnu aktivnost. Sva testirana jedinjenja inhibiraju rast primenjenih kultura gljiva. Najveću aktivnost, koja se može meriti sa aktivnošću komercijalnog antibiotika bifonazola, pokazuje 2-hidroksi-2,6,10-trimetil-7,10-epoksidodeka-3,11-dien-5-on.",
journal = "Journal of the Serbian Chemical Society",
title = "Antifungalna aktivnost terpenoida davanonskog tipa izolovanih iz Artemisia lobelii Var. canescens, Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelli var. conescens",
number = "11",
volume = "69",
pages = "969-972",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_547"
}

Vajs, V., Soković, M., Trifunović, S., Janaćković, P. T., Milosavljević, S.,& Tešević, V.. (2004). Antifungalna aktivnost terpenoida davanonskog tipa izolovanih iz Artemisia lobelii Var. canescens. in Journal of the Serbian Chemical Society, 69(11), 969-972.
https://hdl.handle.net/21.15107/rcub_ibiss_547

Vajs V, Soković M, Trifunović S, Janaćković PT, Milosavljević S, Tešević V. Antifungalna aktivnost terpenoida davanonskog tipa izolovanih iz Artemisia lobelii Var. canescens. in Journal of the Serbian Chemical Society. 2004;69(11):969-972.
https://hdl.handle.net/21.15107/rcub_ibiss_547 .

Vajs, Vlatka, Soković, Marina, Trifunović, Snežana, Janaćković, Peđa T., Milosavljević, Slobodan, Tešević, Vele, "Antifungalna aktivnost terpenoida davanonskog tipa izolovanih iz Artemisia lobelii Var. canescens" in Journal of the Serbian Chemical Society, 69, no. 11 (2004):969-972,
https://hdl.handle.net/21.15107/rcub_ibiss_547 .