dc.contributor | Preedy, Victor R. | |
dc.creator | Arambašić Jovanović, Jelena | |
dc.creator | Mihailović, Mirjana | |
dc.creator | Dinić, Svetlana | |
dc.creator | Grdović, Nevena | |
dc.creator | Uskoković, Aleksandra | |
dc.creator | Poznanović, Goran | |
dc.creator | Vidaković, Melita | |
dc.date.accessioned | 2020-07-08T14:43:35Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2020 | |
dc.identifier.isbn | 978-0-12-815776-3 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/3750 | |
dc.description.abstract | Diabetes is characterized by impaired pancreatic insulin production or an insufficient cellular response to insulin. Hyperglycemia is the main cause of diabetic complications affecting vascular system, kidneys, eyes, peripheral nerves, liver and gastrointestinal system. Hyperglycemia induces overproduction of reactive oxygen species, resulting in impaired cellular function and altered cell signaling. High intracellular glucose levels activate the formation of advanced glycation end-products, the polyol pathway, the hexosamine pathway, and the protein kinase C pathway, affecting gene expression and activity of different regulator proteins. Medicinal mushrooms as source of metabolites (minerals, vitamins, polyphenols, flavonoids, terpenes, alkaloids) have been used in traditional medicine in diabetes treatment for centuries. Lactarius species exhibit a variety of biological activities, including antioxidant, antitumor, and immunostimulatory actions. In this chapter the antioxidant capacity of Lactarius deterrimus and its potential to attenuate the processes that underlie the development and progression of diabetes and diabetes-induced complications will be examined. | en |
dc.language.iso | en | |
dc.publisher | Academic Press | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173020/RS// | |
dc.rights | restrictedAccess | |
dc.source | DIABETES Oxidative Stress and Dietary Antioxidants SECOND EDITION | |
dc.subject | Diabetes | |
dc.subject | Lactarius deterrimus | |
dc.subject | Hyperglycemia | |
dc.subject | Oxidative stress | |
dc.subject | β-cell survival | |
dc.subject | Advanced glycated end-products | |
dc.subject | Reactive oxygen species | |
dc.title | The antioxidant potential of Lactarius deterrimus in diabetes | en |
dc.type | bookPart | |
dc.rights.license | ARR | |
dcterms.abstract | Aрамбашић Јовановић, Јелена; Познановић, Горан; Ускоковић, Aлександра; Грдовић, Невена; Динић, Светлана; Михаиловић, Мирјана; Видаковић, Мелита; | |
dc.rights.holder | © 2020 Elsevier Inc. | |
dc.description.other | Preedy VR, editor. Diabetes: Oxidative Stress and Dietary Antioxidants. 2nd ed. San Diego : Elsevier Science & Technology; 2020. p. 265-73. | |
dc.identifier.doi | 10.1016/B978-0-12-815776-3.00026-7 | |
dc.citation.apa | Arambašić Jovanović, J., Mihailović, M., Dinić, S., Grdović, N., Uskoković, A., Poznanović, G., et al. (2020). The antioxidant potential of Lactarius deterrimus in diabetes. In V. R. Preedy (Ed.), Diabetes: Oxidative Stress and Dietary Antioxidants (2nd ed., pp. 265–273) | |
dc.citation.vancouver | Arambašić Jovanović J, Mihailović M, Dinić S, Grdović N, Uskoković A, Poznanović G, Vidaković M. The antioxidant potential of Lactarius deterrimus in diabetes. In: Preedy VR, editor. Diabetes: Oxidative Stress and Dietary Antioxidants. 2nd ed. San Diego: Elsevier Science & Technology; 2020. p. 265–73. | |
dc.citation.spage | 265 | |
dc.citation.epage | 273 | |
dc.type.version | publishedVersion | |
dc.citation.rank | M13 | |