TY  - JOUR
AU  - Đorđevski, Nikoleta
AU  - Stojković, Dejan
AU  - Živković, Jelena
AU  - Pljevljakušić, Dejan
AU  - Ristanović, Elizabeta
AU  - Nikolić, Biljana
AU  - Ćirić, Ana
PY  - 2022
UR  - https://onlinelibrary.wiley.com/doi/10.1002/fsn3.2777
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4864
AB  - This study was designed to explore functional food properties of edible seed oil obtained from Tamjanika seeds—autochthonous grape variety of Balkan Peninsula. In order to accomplish our goals, seed oil was isolated by Soxhlet apparatus and chemically characterized regarding fatty acids, carotenoids, tocopherols, and tocotrienols. Antimicrobial activity of the isolated oil was tested by microdilution method. For that purposes, six bacterial species were used, belonging to human infectious agents and food contaminants. Furthermore, the activity of the oil was investigated against clinical isolates of dermatomycetes. Our study has shown that oil of Vitis vinifera L. Tamjanika variety was an abundant source of polyunsaturated fatty acids (81.43%) with predominant linoleic acid. HPLC analysis revealed the presence of carotenoid lutein (0.15 mg/100 g). The seed oil was rich in tocotrienols (85.04 mg/100 g) predominating over tocopherols (8.37 mg/100 g). The oil possessed microbicidal activity against all the tested microbes. Bacteria were more sensitive to the effect of the oil (minimum inhibitory concentration [MIC] 7.7–15.4) when compared with oil effect on tested dermatomycetes (MIC 20–40). Our investigation has shown for the first time that grape oil could be active against wide spectrum of bacteria and clinically isolated dermatomycetes. The significance of this study lies in the fact that it pointed out the functional food properties of grape seed oil that was fully chemically characterized.
PB  - John Wiley and Sons Inc
T2  - Food Science & Nutrition
T1  - Tamjanika, a Balkan native variety of Vitis vinifera L.: Chemical characterization, antibacterial, and anti‐dermatomycosis potential of seed oil
IS  - 4
VL  - 10
DO  - 10.1002/fsn3.2777
SP  - 1312
EP  - 1319
ER  - 

@article{
author = "Đorđevski, Nikoleta and Stojković, Dejan and Živković, Jelena and Pljevljakušić, Dejan and Ristanović, Elizabeta and Nikolić, Biljana and Ćirić, Ana",
year = "2022",
abstract = "This study was designed to explore functional food properties of edible seed oil obtained from Tamjanika seeds—autochthonous grape variety of Balkan Peninsula. In order to accomplish our goals, seed oil was isolated by Soxhlet apparatus and chemically characterized regarding fatty acids, carotenoids, tocopherols, and tocotrienols. Antimicrobial activity of the isolated oil was tested by microdilution method. For that purposes, six bacterial species were used, belonging to human infectious agents and food contaminants. Furthermore, the activity of the oil was investigated against clinical isolates of dermatomycetes. Our study has shown that oil of Vitis vinifera L. Tamjanika variety was an abundant source of polyunsaturated fatty acids (81.43%) with predominant linoleic acid. HPLC analysis revealed the presence of carotenoid lutein (0.15 mg/100 g). The seed oil was rich in tocotrienols (85.04 mg/100 g) predominating over tocopherols (8.37 mg/100 g). The oil possessed microbicidal activity against all the tested microbes. Bacteria were more sensitive to the effect of the oil (minimum inhibitory concentration [MIC] 7.7–15.4) when compared with oil effect on tested dermatomycetes (MIC 20–40). Our investigation has shown for the first time that grape oil could be active against wide spectrum of bacteria and clinically isolated dermatomycetes. The significance of this study lies in the fact that it pointed out the functional food properties of grape seed oil that was fully chemically characterized.",
publisher = "John Wiley and Sons Inc",
journal = "Food Science & Nutrition",
title = "Tamjanika, a Balkan native variety of Vitis vinifera L.: Chemical characterization, antibacterial, and anti‐dermatomycosis potential of seed oil",
number = "4",
volume = "10",
doi = "10.1002/fsn3.2777",
pages = "1312-1319"
}

Đorđevski, N., Stojković, D., Živković, J., Pljevljakušić, D., Ristanović, E., Nikolić, B.,& Ćirić, A.. (2022). Tamjanika, a Balkan native variety of Vitis vinifera L.: Chemical characterization, antibacterial, and anti‐dermatomycosis potential of seed oil. in Food Science & Nutrition
John Wiley and Sons Inc., 10(4), 1312-1319.
https://doi.org/10.1002/fsn3.2777

Đorđevski N, Stojković D, Živković J, Pljevljakušić D, Ristanović E, Nikolić B, Ćirić A. Tamjanika, a Balkan native variety of Vitis vinifera L.: Chemical characterization, antibacterial, and anti‐dermatomycosis potential of seed oil. in Food Science & Nutrition. 2022;10(4):1312-1319.
doi:10.1002/fsn3.2777 .

Đorđevski, Nikoleta, Stojković, Dejan, Živković, Jelena, Pljevljakušić, Dejan, Ristanović, Elizabeta, Nikolić, Biljana, Ćirić, Ana, "Tamjanika, a Balkan native variety of Vitis vinifera L.: Chemical characterization, antibacterial, and anti‐dermatomycosis potential of seed oil" in Food Science & Nutrition, 10, no. 4 (2022):1312-1319,
https://doi.org/10.1002/fsn3.2777 . .

TY  - JOUR
AU  - Oalđe, Mariana
AU  - Kolarević, Stoimir
AU  - Živković, Jelena
AU  - Alimpić Aradski, Ana
AU  - Jovanović Marić, Jovana
AU  - Kračun-Kolarević, Margareta
AU  - Đorđević, Jelena
AU  - Marin, Petar D.
AU  - Šavikin, Katarina
AU  - Vuković-Gačić, Branka
AU  - Duletić-Laušević, Sonja
PY  - 2021
UR  - https://pubs.rsc.org/en/content/articlehtml/2021/fo/d1fo00447f
UR  - http://xlink.rsc.org/?DOI=D1FO00447F
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4217
AB  - This research was aimed to assess the potential of Glechoma hederacea, Hyssopus officinalis, Lavandula angustifolia, Leonurus cardiaca, Marrubium vulgare and Sideritis scardica (Lamiaceae) methanolic, ethanolic and aqueous extracts against the damaging effects of oxidative stress using different experimental models. The chemical characterization was done spectrophotometrically by quantifying total phenolics, phenolic acids, flavonoids and flavonols in the extracts, as well as by employing HPLC-DAD technique. Moreover, DPPH assay was used to assess the extracts' radical scavenging potential. Genoprotective properties of the extracts were evaluated using plasmid pUC19 Escherichia coli XL1-Blue, whereas their antigenotoxic potential was determined using Salmonella typhimurium TA1535/pSK1002 and normal human lung fibroblasts. All of the extracts showed antioxidant activity in DPPH assay. Furthermore, the results have shown that aqueous extracts provided the best protection for plasmid DNA, while alcoholic extracts most effectively contributed to the preservation of prokaryotic DNA. Additionally, each of the tested samples significantly protected the eukaryotic cells against genomic damages. Finally, despite not showing exceptional results in DPPH assay, S. scardica extracts are regarded as the most favorable in maintaining the integrity of DNA, which might be due to high quantities of phenolics such as quercetin (up to 17.95 mg g-1), naringin (up to 5.07 mg g-1) and luteolin-7-O-glucoside (up to 3.54 mg g-1). Overall, this comprehensive concept highlights the ability of these Lamiaceae species to safeguard the DNA from reactive oxygen species, to curtail the inflicted damage and also improve the efficiency of the DNA repair mechanisms, while emphasizing the importance of polyphenols as their active principles.
PB  - Royal Society of Chemistry (RSC)
T2  - Food & Function
T1  - A comprehensive assessment of the chemical composition, antioxidant, genoprotective and antigenotoxic activities of Lamiaceae species using different experimental models in vitro
IS  - 7
VL  - 12
DO  - 10.1039/d1fo00447f
SP  - 3233
EP  - 3245
ER  - 

@article{
author = "Oalđe, Mariana and Kolarević, Stoimir and Živković, Jelena and Alimpić Aradski, Ana and Jovanović Marić, Jovana and Kračun-Kolarević, Margareta and Đorđević, Jelena and Marin, Petar D. and Šavikin, Katarina and Vuković-Gačić, Branka and Duletić-Laušević, Sonja",
year = "2021",
abstract = "This research was aimed to assess the potential of Glechoma hederacea, Hyssopus officinalis, Lavandula angustifolia, Leonurus cardiaca, Marrubium vulgare and Sideritis scardica (Lamiaceae) methanolic, ethanolic and aqueous extracts against the damaging effects of oxidative stress using different experimental models. The chemical characterization was done spectrophotometrically by quantifying total phenolics, phenolic acids, flavonoids and flavonols in the extracts, as well as by employing HPLC-DAD technique. Moreover, DPPH assay was used to assess the extracts' radical scavenging potential. Genoprotective properties of the extracts were evaluated using plasmid pUC19 Escherichia coli XL1-Blue, whereas their antigenotoxic potential was determined using Salmonella typhimurium TA1535/pSK1002 and normal human lung fibroblasts. All of the extracts showed antioxidant activity in DPPH assay. Furthermore, the results have shown that aqueous extracts provided the best protection for plasmid DNA, while alcoholic extracts most effectively contributed to the preservation of prokaryotic DNA. Additionally, each of the tested samples significantly protected the eukaryotic cells against genomic damages. Finally, despite not showing exceptional results in DPPH assay, S. scardica extracts are regarded as the most favorable in maintaining the integrity of DNA, which might be due to high quantities of phenolics such as quercetin (up to 17.95 mg g-1), naringin (up to 5.07 mg g-1) and luteolin-7-O-glucoside (up to 3.54 mg g-1). Overall, this comprehensive concept highlights the ability of these Lamiaceae species to safeguard the DNA from reactive oxygen species, to curtail the inflicted damage and also improve the efficiency of the DNA repair mechanisms, while emphasizing the importance of polyphenols as their active principles.",
publisher = "Royal Society of Chemistry (RSC)",
journal = "Food & Function",
title = "A comprehensive assessment of the chemical composition, antioxidant, genoprotective and antigenotoxic activities of Lamiaceae species using different experimental models in vitro",
number = "7",
volume = "12",
doi = "10.1039/d1fo00447f",
pages = "3233-3245"
}

Oalđe, M., Kolarević, S., Živković, J., Alimpić Aradski, A., Jovanović Marić, J., Kračun-Kolarević, M., Đorđević, J., Marin, P. D., Šavikin, K., Vuković-Gačić, B.,& Duletić-Laušević, S.. (2021). A comprehensive assessment of the chemical composition, antioxidant, genoprotective and antigenotoxic activities of Lamiaceae species using different experimental models in vitro. in Food & Function
Royal Society of Chemistry (RSC)., 12(7), 3233-3245.
https://doi.org/10.1039/d1fo00447f

Oalđe M, Kolarević S, Živković J, Alimpić Aradski A, Jovanović Marić J, Kračun-Kolarević M, Đorđević J, Marin PD, Šavikin K, Vuković-Gačić B, Duletić-Laušević S. A comprehensive assessment of the chemical composition, antioxidant, genoprotective and antigenotoxic activities of Lamiaceae species using different experimental models in vitro. in Food & Function. 2021;12(7):3233-3245.
doi:10.1039/d1fo00447f .

Oalđe, Mariana, Kolarević, Stoimir, Živković, Jelena, Alimpić Aradski, Ana, Jovanović Marić, Jovana, Kračun-Kolarević, Margareta, Đorđević, Jelena, Marin, Petar D., Šavikin, Katarina, Vuković-Gačić, Branka, Duletić-Laušević, Sonja, "A comprehensive assessment of the chemical composition, antioxidant, genoprotective and antigenotoxic activities of Lamiaceae species using different experimental models in vitro" in Food & Function, 12, no. 7 (2021):3233-3245,
https://doi.org/10.1039/d1fo00447f . .

TY  - JOUR
AU  - Živković, Jelena
AU  - Ivanov, Marija
AU  - Stojković, Dejan
AU  - Glamočlija, Jasmina
PY  - 2021
UR  - https://doi.org/10.3390/jof7050349
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4243
AB  - This study aims to fill the gaps in ethnomycological knowledge in Serbia by identifying various fungal species that have been used due to their medicinal or nutritional properties. Eth-nomycological information was gathered using semi-structured interviews with participants from different mycological associations in Serbia. A total of 62 participants were involved in this study. Eighty-five species belonging to 28 families were identified. All of the reported fungal species were pointed out as edible, and only 15 of them were declared as medicinal. The family Boletaceae was represented by the highest number of species, followed by Russulaceae, Agaricaceae and Polypo-raceae. We also performed detailed analysis of the literature in order to provide scientific evidence for the recorded medicinal use of fungi in Serbia. The male participants reported a higher level of ethnomycological knowledge compared to women, whereas the highest number of used fungi species was mentioned by participants within the age group of 61–80 years. In addition to pre-serving ethnomycological knowledge in Serbia, this study can present a good starting point for further pharmacological investigations of fungi.
PB  - MDPI AG
T2  - Journal of Fungi
T1  - Ethnomycological investigation in serbia: Astonishing realm of mycomedicines and mycofood
IS  - 5
VL  - 7
DO  - 10.3390/jof7050349
SP  - 349
ER  - 

@article{
author = "Živković, Jelena and Ivanov, Marija and Stojković, Dejan and Glamočlija, Jasmina",
year = "2021",
abstract = "This study aims to fill the gaps in ethnomycological knowledge in Serbia by identifying various fungal species that have been used due to their medicinal or nutritional properties. Eth-nomycological information was gathered using semi-structured interviews with participants from different mycological associations in Serbia. A total of 62 participants were involved in this study. Eighty-five species belonging to 28 families were identified. All of the reported fungal species were pointed out as edible, and only 15 of them were declared as medicinal. The family Boletaceae was represented by the highest number of species, followed by Russulaceae, Agaricaceae and Polypo-raceae. We also performed detailed analysis of the literature in order to provide scientific evidence for the recorded medicinal use of fungi in Serbia. The male participants reported a higher level of ethnomycological knowledge compared to women, whereas the highest number of used fungi species was mentioned by participants within the age group of 61–80 years. In addition to pre-serving ethnomycological knowledge in Serbia, this study can present a good starting point for further pharmacological investigations of fungi.",
publisher = "MDPI AG",
journal = "Journal of Fungi",
title = "Ethnomycological investigation in serbia: Astonishing realm of mycomedicines and mycofood",
number = "5",
volume = "7",
doi = "10.3390/jof7050349",
pages = "349"
}

Živković, J., Ivanov, M., Stojković, D.,& Glamočlija, J.. (2021). Ethnomycological investigation in serbia: Astonishing realm of mycomedicines and mycofood. in Journal of Fungi
MDPI AG., 7(5), 349.
https://doi.org/10.3390/jof7050349

Živković J, Ivanov M, Stojković D, Glamočlija J. Ethnomycological investigation in serbia: Astonishing realm of mycomedicines and mycofood. in Journal of Fungi. 2021;7(5):349.
doi:10.3390/jof7050349 .

Živković, Jelena, Ivanov, Marija, Stojković, Dejan, Glamočlija, Jasmina, "Ethnomycological investigation in serbia: Astonishing realm of mycomedicines and mycofood" in Journal of Fungi, 7, no. 5 (2021):349,
https://doi.org/10.3390/jof7050349 . .

TY  - JOUR
AU  - Savić, Aleksandra
AU  - Alimpić Aradski, Ana
AU  - Živković, Jelena
AU  - Šavikin, Katarina
AU  - Jarić, Snežana
AU  - Marin, Petar
AU  - Duletić-Laušević, Sonja
PY  - 2021
UR  - http://journal.pan.olsztyn.pl/Phenolic-Composition-and-Antioxidant-and-Antineurodegenerative-Potential-of-Methanolic,138320,0,2.html
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4416
AB  - Pear (Pyrus communis L.) is consumed as fresh fruit, in numerous food products, and also used as a traditional remedy in various countries, including Serbia. In search of bioactive compounds, six traditional pear varieties (‘Vidovača’, ‘Lubeničarka’, ‘Karamanka’, ‘Jeribasma’, ‘Lončara’, ‘Takiša’) and wild pear from Serbia were investigated and compared with a commercial variety (‘Williams Bartlett’). The aim of this study was to determine the total phenolic and flavonoid contents, phenolic composition, antioxidant capacity, and antineurodegenerative activities of methanolic extracts of peel, flesh, and mixed peel and flesh of pear fruits. Phenolic composition of extracts was determined with HPLC-DAD, while the antioxidant activity of extracts was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), and ferric-reducing antioxidant power (FRAP) assays. Bearing in mind that oxidative stress is closely linked to neurodegeneration, the antineurodegenerative potential of the extracts was assessed by the inhibition of acetycholineserase (AChE) and tyrosinase (TYR) activities. The extracts of traditional varieties, particularly peel extracts, had a high content of phenolics, as well as significant antioxidant and moderate antineurodegenerative potential, compared to the commercial variety. The highest contents of total flavonoids and individual compounds, such as arbutin and chlorogenic acid, as well as the strongest antioxidant and TYR inhibitory activities were reported for the ‘Takiša’ peel extract. The performed analyses have revealed that fruits of traditional Serbian pear varieties are rich in bioactive components and could be used as functional food and for possible nutraceutical applications, to prevent diseases induced by oxidative stress.
T2  - Polish Journal of Food and Nutrition Sciences
T1  - Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia
IS  - 2
VL  - 71
DO  - 10.31883/pjfns/138320
SP  - 225
EP  - 236
ER  - 

@article{
author = "Savić, Aleksandra and Alimpić Aradski, Ana and Živković, Jelena and Šavikin, Katarina and Jarić, Snežana and Marin, Petar and Duletić-Laušević, Sonja",
year = "2021",
abstract = "Pear (Pyrus communis L.) is consumed as fresh fruit, in numerous food products, and also used as a traditional remedy in various countries, including Serbia. In search of bioactive compounds, six traditional pear varieties (‘Vidovača’, ‘Lubeničarka’, ‘Karamanka’, ‘Jeribasma’, ‘Lončara’, ‘Takiša’) and wild pear from Serbia were investigated and compared with a commercial variety (‘Williams Bartlett’). The aim of this study was to determine the total phenolic and flavonoid contents, phenolic composition, antioxidant capacity, and antineurodegenerative activities of methanolic extracts of peel, flesh, and mixed peel and flesh of pear fruits. Phenolic composition of extracts was determined with HPLC-DAD, while the antioxidant activity of extracts was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), and ferric-reducing antioxidant power (FRAP) assays. Bearing in mind that oxidative stress is closely linked to neurodegeneration, the antineurodegenerative potential of the extracts was assessed by the inhibition of acetycholineserase (AChE) and tyrosinase (TYR) activities. The extracts of traditional varieties, particularly peel extracts, had a high content of phenolics, as well as significant antioxidant and moderate antineurodegenerative potential, compared to the commercial variety. The highest contents of total flavonoids and individual compounds, such as arbutin and chlorogenic acid, as well as the strongest antioxidant and TYR inhibitory activities were reported for the ‘Takiša’ peel extract. The performed analyses have revealed that fruits of traditional Serbian pear varieties are rich in bioactive components and could be used as functional food and for possible nutraceutical applications, to prevent diseases induced by oxidative stress.",
journal = "Polish Journal of Food and Nutrition Sciences",
title = "Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia",
number = "2",
volume = "71",
doi = "10.31883/pjfns/138320",
pages = "225-236"
}

Savić, A., Alimpić Aradski, A., Živković, J., Šavikin, K., Jarić, S., Marin, P.,& Duletić-Laušević, S.. (2021). Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia. in Polish Journal of Food and Nutrition Sciences, 71(2), 225-236.
https://doi.org/10.31883/pjfns/138320

Savić A, Alimpić Aradski A, Živković J, Šavikin K, Jarić S, Marin P, Duletić-Laušević S. Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia. in Polish Journal of Food and Nutrition Sciences. 2021;71(2):225-236.
doi:10.31883/pjfns/138320 .

Savić, Aleksandra, Alimpić Aradski, Ana, Živković, Jelena, Šavikin, Katarina, Jarić, Snežana, Marin, Petar, Duletić-Laušević, Sonja, "Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia" in Polish Journal of Food and Nutrition Sciences, 71, no. 2 (2021):225-236,
https://doi.org/10.31883/pjfns/138320 . .

TY  - JOUR
AU  - Živković, Jelena
AU  - Stojković, Dejan
AU  - Petrović, Jovana
AU  - Zdunić, Gordana
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2039
AB  - Health beneficial properties of Rosa canina species are mainly
   attributed to rose hips, while the leaves are usually discarded as
   waste. In the present study we investigated chemical constituents as
   well as antimicrobial and antibiofilm potential of R. canina methanolic
   leaf extract. Chemical analysis showed that dominant phenolic compounds
   are quercetin and isorhamnetin derivatives (isoquercetin and
   isorhamnetin-3-O-rutinoside). Among the tested bacteria, Pseudomonas
   aeruginosa and Salmonella typhimurium were the most susceptible to the
   activity of R. canina leaf extract with MIC and MBC values both 0.009 mg
   mL(-1). For most of the bacterial strains investigated the extract
   showed significantly higher activity compared to the used standard
   compounds streptomycin and ampicillin. Also the tested extract
   powerfully inhibited in vitro biofilm growth in Pseudomonas aeruginosa,
   Staphylococcus aureus, Leishmania monocytogenes and Escherichia coli at
   sub MIC-levels. With concentrations equal to 1/4 and 1/8 of MIC values
   biofilm growth of P. aeruginosa and E. coli was inhibited by 90\%. The
   obtained results are significant for a wider and efficient use of R.
   canina leaves.
T2  - Food & Function
T1  - Rosa canina L. - new possibilities for an old medicinal herb
IS  - 12
VL  - 6
DO  - 10.1039/c5fo00820d
SP  - 3687
EP  - 3692
ER  - 

@article{
author = "Živković, Jelena and Stojković, Dejan and Petrović, Jovana and Zdunić, Gordana and Glamočlija, Jasmina and Soković, Marina",
year = "2015",
abstract = "Health beneficial properties of Rosa canina species are mainly
   attributed to rose hips, while the leaves are usually discarded as
   waste. In the present study we investigated chemical constituents as
   well as antimicrobial and antibiofilm potential of R. canina methanolic
   leaf extract. Chemical analysis showed that dominant phenolic compounds
   are quercetin and isorhamnetin derivatives (isoquercetin and
   isorhamnetin-3-O-rutinoside). Among the tested bacteria, Pseudomonas
   aeruginosa and Salmonella typhimurium were the most susceptible to the
   activity of R. canina leaf extract with MIC and MBC values both 0.009 mg
   mL(-1). For most of the bacterial strains investigated the extract
   showed significantly higher activity compared to the used standard
   compounds streptomycin and ampicillin. Also the tested extract
   powerfully inhibited in vitro biofilm growth in Pseudomonas aeruginosa,
   Staphylococcus aureus, Leishmania monocytogenes and Escherichia coli at
   sub MIC-levels. With concentrations equal to 1/4 and 1/8 of MIC values
   biofilm growth of P. aeruginosa and E. coli was inhibited by 90\%. The
   obtained results are significant for a wider and efficient use of R.
   canina leaves.",
journal = "Food & Function",
title = "Rosa canina L. - new possibilities for an old medicinal herb",
number = "12",
volume = "6",
doi = "10.1039/c5fo00820d",
pages = "3687-3692"
}

Živković, J., Stojković, D., Petrović, J., Zdunić, G., Glamočlija, J.,& Soković, M.. (2015). Rosa canina L. - new possibilities for an old medicinal herb. in Food & Function, 6(12), 3687-3692.
https://doi.org/10.1039/c5fo00820d

Živković J, Stojković D, Petrović J, Zdunić G, Glamočlija J, Soković M. Rosa canina L. - new possibilities for an old medicinal herb. in Food & Function. 2015;6(12):3687-3692.
doi:10.1039/c5fo00820d .

Živković, Jelena, Stojković, Dejan, Petrović, Jovana, Zdunić, Gordana, Glamočlija, Jasmina, Soković, Marina, "Rosa canina L. - new possibilities for an old medicinal herb" in Food & Function, 6, no. 12 (2015):3687-3692,
https://doi.org/10.1039/c5fo00820d . .

TY  - JOUR
AU  - Ignjatović, Đurđica
AU  - Živković, Jelena
AU  - Tovilović-Kovačević, Gordana
AU  - Savikin, Katarina
AU  - Tomić, Mirko
AU  - Maksimović, Zoran
AU  - Jankovic, Teodora
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1973
AB  - Methanol and 70\% acetone extracts from Veronica jacquinii, Veronica
   urticifolia and Veronica teucrium were evaluated regarding their
   neuroprotective/antioxidant effects on the human neuroblastoma SH-SY5Y
   cell line. All extracts exhibited modest protective activity by
   increasing cell survival in cells stressed with sodium nitroprusside
   (9-12\%) and hydrogen peroxide (16-21\%) compared to non-treated cells.
   These activities were accompanied by reductions in the amount of
   superoxide radicals and index of lipid peroxidation. Extracts were
   further analysed for the content of total phenolics, phenylpropanoid
   glycosides and iridoids, and the major compounds acteoside and aucubin.
   The highest amount of total phenolics was observed in V. jacquinii,
   while V. teucrium was richest in total iridoids, acteoside and aucubin.
   Angiogenic properties on EA.hy926 human endothelial cells were also
   examined. At the highest non-toxic concentration (25 mu g/ml), the
   tested extracts inhibited spontaneous tube formation of endothelial
   cells on the extracellular matrix, implying their possible
   antiangiogenic activity. The most potent inhibitory effects were shown
   by methanol extract of V. jacquinii and aqueous acetone extract of V.
   teucrium. The extracts did not significantly change the adhesive or
   migratory capacity of EA.hy926 cells. Considering the traditional use of
   Veronica species, these results suggest a need for further assessment of
   their supposed wound-healing properties.
T2  - Frontiers in Life Science
T1  - Evaluation of angiogenic and neuroprotective potential of different
 extracts from three Veronica species
IS  - 2
VL  - 8
DO  - 10.1080/21553769.2014.998297
SP  - 107
EP  - 116
ER  - 

@article{
author = "Ignjatović, Đurđica and Živković, Jelena and Tovilović-Kovačević, Gordana and Savikin, Katarina and Tomić, Mirko and Maksimović, Zoran and Jankovic, Teodora",
year = "2015",
abstract = "Methanol and 70\% acetone extracts from Veronica jacquinii, Veronica
   urticifolia and Veronica teucrium were evaluated regarding their
   neuroprotective/antioxidant effects on the human neuroblastoma SH-SY5Y
   cell line. All extracts exhibited modest protective activity by
   increasing cell survival in cells stressed with sodium nitroprusside
   (9-12\%) and hydrogen peroxide (16-21\%) compared to non-treated cells.
   These activities were accompanied by reductions in the amount of
   superoxide radicals and index of lipid peroxidation. Extracts were
   further analysed for the content of total phenolics, phenylpropanoid
   glycosides and iridoids, and the major compounds acteoside and aucubin.
   The highest amount of total phenolics was observed in V. jacquinii,
   while V. teucrium was richest in total iridoids, acteoside and aucubin.
   Angiogenic properties on EA.hy926 human endothelial cells were also
   examined. At the highest non-toxic concentration (25 mu g/ml), the
   tested extracts inhibited spontaneous tube formation of endothelial
   cells on the extracellular matrix, implying their possible
   antiangiogenic activity. The most potent inhibitory effects were shown
   by methanol extract of V. jacquinii and aqueous acetone extract of V.
   teucrium. The extracts did not significantly change the adhesive or
   migratory capacity of EA.hy926 cells. Considering the traditional use of
   Veronica species, these results suggest a need for further assessment of
   their supposed wound-healing properties.",
journal = "Frontiers in Life Science",
title = "Evaluation of angiogenic and neuroprotective potential of different
 extracts from three Veronica species",
number = "2",
volume = "8",
doi = "10.1080/21553769.2014.998297",
pages = "107-116"
}

Ignjatović, Đ., Živković, J., Tovilović-Kovačević, G., Savikin, K., Tomić, M., Maksimović, Z.,& Jankovic, T.. (2015). Evaluation of angiogenic and neuroprotective potential of different
 extracts from three Veronica species. in Frontiers in Life Science, 8(2), 107-116.
https://doi.org/10.1080/21553769.2014.998297

Ignjatović Đ, Živković J, Tovilović-Kovačević G, Savikin K, Tomić M, Maksimović Z, Jankovic T. Evaluation of angiogenic and neuroprotective potential of different
 extracts from three Veronica species. in Frontiers in Life Science. 2015;8(2):107-116.
doi:10.1080/21553769.2014.998297 .

Ignjatović, Đurđica, Živković, Jelena, Tovilović-Kovačević, Gordana, Savikin, Katarina, Tomić, Mirko, Maksimović, Zoran, Jankovic, Teodora, "Evaluation of angiogenic and neuroprotective potential of different
 extracts from three Veronica species" in Frontiers in Life Science, 8, no. 2 (2015):107-116,
https://doi.org/10.1080/21553769.2014.998297 . .

TY  - JOUR
AU  - Barreira, Joao C. M.
AU  - Dias, Maria Ines
AU  - Zivkovic, Jelena
AU  - Stojković, Dejan
AU  - Soković, Marina
AU  - Santos-Buelga, Celestino
AU  - Ferreira, Isabel C. F. R.
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2123
AB  - Veronica (Plantaginaceae) genus is widely distributed in different
   habitats. The phenolic compounds of Veronica montana, Veronica polita
   and Veronica spuria were tentatively identified by HPLC-DAD-ESI/MS. The
   phenolic profiles showed that flavones were the major compounds (V.
   montana: 7 phenolic acids, 5 flavones, 4 phenylethanoids and 1
   isoflavone; V. polita: 10 flavones, 5 phenolic acids, 2 phenylethanoids,
   1 flavonol and 1 isoflavone; V. spuria: 10 phenolic acids, 5 flavones, 2
   flavonols, 2 phenylethanoids and 1 isoflavone). V. spuria possessed the
   highest contents in all groups of phenolic compounds, except flavones,
   which did not show differences among the assayed species. Overall, these
   species might be considered good sources of phenolic compounds for
   industrial or pharmacological applications. (C) 2014 Elsevier Ltd. All
   rights reserved.
T2  - Food Chemistry
T1  - Phenolic profiling of Veronica spp. grown in mountain, urban and sandy
 soil environments
VL  - 163
DO  - 10.1016/j.foodchem.2014.04.117
SP  - 275
EP  - 283
ER  - 

@article{
author = "Barreira, Joao C. M. and Dias, Maria Ines and Zivkovic, Jelena and Stojković, Dejan and Soković, Marina and Santos-Buelga, Celestino and Ferreira, Isabel C. F. R.",
year = "2014",
abstract = "Veronica (Plantaginaceae) genus is widely distributed in different
   habitats. The phenolic compounds of Veronica montana, Veronica polita
   and Veronica spuria were tentatively identified by HPLC-DAD-ESI/MS. The
   phenolic profiles showed that flavones were the major compounds (V.
   montana: 7 phenolic acids, 5 flavones, 4 phenylethanoids and 1
   isoflavone; V. polita: 10 flavones, 5 phenolic acids, 2 phenylethanoids,
   1 flavonol and 1 isoflavone; V. spuria: 10 phenolic acids, 5 flavones, 2
   flavonols, 2 phenylethanoids and 1 isoflavone). V. spuria possessed the
   highest contents in all groups of phenolic compounds, except flavones,
   which did not show differences among the assayed species. Overall, these
   species might be considered good sources of phenolic compounds for
   industrial or pharmacological applications. (C) 2014 Elsevier Ltd. All
   rights reserved.",
journal = "Food Chemistry",
title = "Phenolic profiling of Veronica spp. grown in mountain, urban and sandy
 soil environments",
volume = "163",
doi = "10.1016/j.foodchem.2014.04.117",
pages = "275-283"
}

Barreira, J. C. M., Dias, M. I., Zivkovic, J., Stojković, D., Soković, M., Santos-Buelga, C.,& Ferreira, I. C. F. R.. (2014). Phenolic profiling of Veronica spp. grown in mountain, urban and sandy
 soil environments. in Food Chemistry, 163, 275-283.
https://doi.org/10.1016/j.foodchem.2014.04.117

Barreira JCM, Dias MI, Zivkovic J, Stojković D, Soković M, Santos-Buelga C, Ferreira ICFR. Phenolic profiling of Veronica spp. grown in mountain, urban and sandy
 soil environments. in Food Chemistry. 2014;163:275-283.
doi:10.1016/j.foodchem.2014.04.117 .

Barreira, Joao C. M., Dias, Maria Ines, Zivkovic, Jelena, Stojković, Dejan, Soković, Marina, Santos-Buelga, Celestino, Ferreira, Isabel C. F. R., "Phenolic profiling of Veronica spp. grown in mountain, urban and sandy
 soil environments" in Food Chemistry, 163 (2014):275-283,
https://doi.org/10.1016/j.foodchem.2014.04.117 . .

TY  - JOUR
AU  - Jelenković, Ankica V.
AU  - Jovanovic, Marina D.
AU  - Stevanovic, Ivana
AU  - Petronijevic, Natasa
AU  - Bokonjic, Dubravko
AU  - Zivkovic, Jelena
AU  - Igic, Rajko
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2306
AB  - Aluminium may have an important role in the
   aetiology/pathogenesis/precipitation of Alzheimer's disease. Because
   green tea (Camellia sinensis L.) reportedly has health-promoting effects
   in the central nervous system, we evaluated the effects of green tea
   leaf extract (GTLE) on aluminium chloride (AlCl3) neurotoxicity in rats.
   All solutions were injected into the cornu ammonis region 1 hippocampal
   region. We measured the performance of active avoidance (AA) tasks,
   various enzyme activities and total glutathione content (TGC) in the
   forebrain cortex (FbC), striatum, basal forebrain (BFb), hippocampus,
   brain stem and cerebellum. AlCl3 markedly reduced AA performance and
   activities of cytochrome c oxidase (COX) and acetylcholinesterase (AChE)
   in all regions. It decreased TGC in the FbC, striatum, BFb, hippocampus,
   brain stem and cerebellum, and increased superoxide dismutase activity
   in the FbC, cerebellum and BFb. GTLE pretreatment completely reversed
   the damaging effects of AlCl3 on AA and superoxide dismutase activity,
   markedly corrected COX and AChE activities, and moderately improved TGC.
   GTLE alone increased COX and AChE activities in almost all regions. GTLE
   reduces AlCl3 neurotoxicity probably via antioxidative effects and
   improves mitochondrial and cholinergic synaptic functions through the
   actions of (-)-epigallocatechin gallate and (-)-epicatechin, compounds
   most abundantly found in GTLE. Our results suggest that green tea might
   be beneficial in Alzheimer's disease. Copyright (c) 2013 John Wiley \&
   Sons, Ltd.
T2  - Phytotherapy Research
T1  - Influence of the Green Tea Leaf Extract on Neurotoxicity of Aluminium
 Chloride in Rats
IS  - 1
VL  - 28
DO  - 10.1002/ptr.4962
SP  - 82
EP  - 87
ER  - 

@article{
author = "Jelenković, Ankica V. and Jovanovic, Marina D. and Stevanovic, Ivana and Petronijevic, Natasa and Bokonjic, Dubravko and Zivkovic, Jelena and Igic, Rajko",
year = "2014",
abstract = "Aluminium may have an important role in the
   aetiology/pathogenesis/precipitation of Alzheimer's disease. Because
   green tea (Camellia sinensis L.) reportedly has health-promoting effects
   in the central nervous system, we evaluated the effects of green tea
   leaf extract (GTLE) on aluminium chloride (AlCl3) neurotoxicity in rats.
   All solutions were injected into the cornu ammonis region 1 hippocampal
   region. We measured the performance of active avoidance (AA) tasks,
   various enzyme activities and total glutathione content (TGC) in the
   forebrain cortex (FbC), striatum, basal forebrain (BFb), hippocampus,
   brain stem and cerebellum. AlCl3 markedly reduced AA performance and
   activities of cytochrome c oxidase (COX) and acetylcholinesterase (AChE)
   in all regions. It decreased TGC in the FbC, striatum, BFb, hippocampus,
   brain stem and cerebellum, and increased superoxide dismutase activity
   in the FbC, cerebellum and BFb. GTLE pretreatment completely reversed
   the damaging effects of AlCl3 on AA and superoxide dismutase activity,
   markedly corrected COX and AChE activities, and moderately improved TGC.
   GTLE alone increased COX and AChE activities in almost all regions. GTLE
   reduces AlCl3 neurotoxicity probably via antioxidative effects and
   improves mitochondrial and cholinergic synaptic functions through the
   actions of (-)-epigallocatechin gallate and (-)-epicatechin, compounds
   most abundantly found in GTLE. Our results suggest that green tea might
   be beneficial in Alzheimer's disease. Copyright (c) 2013 John Wiley \&
   Sons, Ltd.",
journal = "Phytotherapy Research",
title = "Influence of the Green Tea Leaf Extract on Neurotoxicity of Aluminium
 Chloride in Rats",
number = "1",
volume = "28",
doi = "10.1002/ptr.4962",
pages = "82-87"
}

Jelenković, A. V., Jovanovic, M. D., Stevanovic, I., Petronijevic, N., Bokonjic, D., Zivkovic, J.,& Igic, R.. (2014). Influence of the Green Tea Leaf Extract on Neurotoxicity of Aluminium
 Chloride in Rats. in Phytotherapy Research, 28(1), 82-87.
https://doi.org/10.1002/ptr.4962

Jelenković AV, Jovanovic MD, Stevanovic I, Petronijevic N, Bokonjic D, Zivkovic J, Igic R. Influence of the Green Tea Leaf Extract on Neurotoxicity of Aluminium
 Chloride in Rats. in Phytotherapy Research. 2014;28(1):82-87.
doi:10.1002/ptr.4962 .

Jelenković, Ankica V., Jovanovic, Marina D., Stevanovic, Ivana, Petronijevic, Natasa, Bokonjic, Dubravko, Zivkovic, Jelena, Igic, Rajko, "Influence of the Green Tea Leaf Extract on Neurotoxicity of Aluminium
 Chloride in Rats" in Phytotherapy Research, 28, no. 1 (2014):82-87,
https://doi.org/10.1002/ptr.4962 . .

TY  - JOUR
AU  - Zivkovic, Jelena
AU  - Barreira, Joao C. M.
AU  - Stojković, Dejan
AU  - Cebovic, Tatjana
AU  - Santos-Buelga, Celestino
AU  - Maksimovic, Zoran
AU  - Ferreira, Isabel C. F. R.
PY  - 2014
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2196
AB  - The phenolic profile and antibacterial, antimutagenic and antitumour
   activities of the methanolic extracts of Veronica urticifolia Jacq. were
   evaluated. HPLC-DAD/ESI-MS analysis revealed the presence of phenolic
   acids, flavonoids and phenylethanoids, with acteoside as the main
   component (14.9 mg/g of extract). Antibacterial effect was determined
   using the microbroth dilution assay and Staphylococcus aureus was the
   most sensitive strain (MIC and MBC = 7.5 mg/mL). Antimutagenic activity
   was evaluated by Ames mutagenicity assay. At 1 mg/plate, the tested
   extract afforded high protection against the mutagenicity of
   nitroquinoline-N-oxide (4NQO) to Salmonella typhimurium strain TA100
   (inhibition rate 48.3\%). Antitumour activity was screened in Ehrlich
   ascites carcinoma (EAC) model. Pretreatment with 2 mg/kg body weight
   showed statistically significant decrease in tumour cell viability,
   while ascites volume and tumour cell count became slightly decreased,
   but not to a statistically significant extent. The results indicate that
   V. urticifolia deserves further research into its potential
   chemoprevention effects. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Journal of Functional Foods
T1  - Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.
VL  - 9
DO  - 10.1016/j.jff.2014.04.024
SP  - 192
EP  - 201
ER  - 

@article{
author = "Zivkovic, Jelena and Barreira, Joao C. M. and Stojković, Dejan and Cebovic, Tatjana and Santos-Buelga, Celestino and Maksimovic, Zoran and Ferreira, Isabel C. F. R.",
year = "2014",
abstract = "The phenolic profile and antibacterial, antimutagenic and antitumour
   activities of the methanolic extracts of Veronica urticifolia Jacq. were
   evaluated. HPLC-DAD/ESI-MS analysis revealed the presence of phenolic
   acids, flavonoids and phenylethanoids, with acteoside as the main
   component (14.9 mg/g of extract). Antibacterial effect was determined
   using the microbroth dilution assay and Staphylococcus aureus was the
   most sensitive strain (MIC and MBC = 7.5 mg/mL). Antimutagenic activity
   was evaluated by Ames mutagenicity assay. At 1 mg/plate, the tested
   extract afforded high protection against the mutagenicity of
   nitroquinoline-N-oxide (4NQO) to Salmonella typhimurium strain TA100
   (inhibition rate 48.3\%). Antitumour activity was screened in Ehrlich
   ascites carcinoma (EAC) model. Pretreatment with 2 mg/kg body weight
   showed statistically significant decrease in tumour cell viability,
   while ascites volume and tumour cell count became slightly decreased,
   but not to a statistically significant extent. The results indicate that
   V. urticifolia deserves further research into its potential
   chemoprevention effects. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Journal of Functional Foods",
title = "Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.",
volume = "9",
doi = "10.1016/j.jff.2014.04.024",
pages = "192-201"
}

Zivkovic, J., Barreira, J. C. M., Stojković, D., Cebovic, T., Santos-Buelga, C., Maksimovic, Z.,& Ferreira, I. C. F. R.. (2014). Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.. in Journal of Functional Foods, 9, 192-201.
https://doi.org/10.1016/j.jff.2014.04.024

Zivkovic J, Barreira JCM, Stojković D, Cebovic T, Santos-Buelga C, Maksimovic Z, Ferreira ICFR. Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq.. in Journal of Functional Foods. 2014;9:192-201.
doi:10.1016/j.jff.2014.04.024 .

Zivkovic, Jelena, Barreira, Joao C. M., Stojković, Dejan, Cebovic, Tatjana, Santos-Buelga, Celestino, Maksimovic, Zoran, Ferreira, Isabel C. F. R., "Phenolic profile, antibacterial, antimutagenic and antitumour evaluation
 of Veronica urticifolia Jacq." in Journal of Functional Foods, 9 (2014):192-201,
https://doi.org/10.1016/j.jff.2014.04.024 . .