TY  - CONF
AU  - Zavišić, Gordana
AU  - Ristić, Slavica
AU  - Petković, Branka
AU  - Janković, Drina
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6538
AB  - Considering the importance of the microbiological correctness of food 
from the aspect of health safety and the most common causes of food contamination 
(bacteria) – the causes of alimentary intoxications and toxoinfections in humans, 
whether sporadic or epidemic, this work aims to analyze and sublimate the most 
common bacterial species isolated from contaminated food and biological samples of 
individuals with alimentary intoxication or toxoinfection. At the global level and 
especially based on the cases reported by the European Center for Disease Control and 
Prevention (ECDC) and the World Health Organization (WHO) for 2022, a trend of 
increasing epidemics caused by microbiologically contaminated food has been 
observed. The latest data from the U.S. Food and Drug Administration (FDA) and 
ECDC show that epidemics caused by Salmonella typhimurium, Escherichia coli, 
Yersinia spp., and Campylobacter spp. are increasing compared with 2021. The highest 
reporting rate was among young children aged 0 to 4 years. The most common 
pathogens are Salmonella Enteritidis and Salmonella Typhimurium, resulting in 61,236 
cases of salmonellosis reported in 30 countries, 14% more than in 2020 (53,163 cases). 
In 2021, there were 6,534 cases of Shiga toxin-producing E. coli infection compared 
with 4,824 in 2020. Similarly, Yersinia spp. and most commonly Y. enterocolitica 
caused 6,876 cases of yersiniosis in 2021 compared with 5,747 in 2020, and also 
deaths. The conclusion is that eggs and egg products remain the most dangerous foods 
in epidemics, but several major incidents have been linked to contaminated vegetables 
(especially lettuce), fruits, and sesame seeds. To prove the genetic link, i.e., that the 
bacteria have the same origin in different sick individuals, the entire genome must be 
sequenced. In the suppressing epidemics, food storage and preservation conditions, 
lettuce washing, handling-washing, cleaning and disinfection in food preparation 
areas, and distribution are of particular importance.
PB  - Prijedor: Public Institution College of Health Sciences
C3  - 2nd International Conference: Knowledge to Health: SANUS 2023. Book 2, Proceedings; 2023 Jun 23-24; Prijedor, Bosnia and Herzegovina
T1  - Microbiological quality and the most common food contaminants
DO  - 10.7251/ZSAN2302261Z
SP  - 261
EP  - 270
ER  - 

@conference{
author = "Zavišić, Gordana and Ristić, Slavica and Petković, Branka and Janković, Drina",
year = "2023",
abstract = "Considering the importance of the microbiological correctness of food 
from the aspect of health safety and the most common causes of food contamination 
(bacteria) – the causes of alimentary intoxications and toxoinfections in humans, 
whether sporadic or epidemic, this work aims to analyze and sublimate the most 
common bacterial species isolated from contaminated food and biological samples of 
individuals with alimentary intoxication or toxoinfection. At the global level and 
especially based on the cases reported by the European Center for Disease Control and 
Prevention (ECDC) and the World Health Organization (WHO) for 2022, a trend of 
increasing epidemics caused by microbiologically contaminated food has been 
observed. The latest data from the U.S. Food and Drug Administration (FDA) and 
ECDC show that epidemics caused by Salmonella typhimurium, Escherichia coli, 
Yersinia spp., and Campylobacter spp. are increasing compared with 2021. The highest 
reporting rate was among young children aged 0 to 4 years. The most common 
pathogens are Salmonella Enteritidis and Salmonella Typhimurium, resulting in 61,236 
cases of salmonellosis reported in 30 countries, 14% more than in 2020 (53,163 cases). 
In 2021, there were 6,534 cases of Shiga toxin-producing E. coli infection compared 
with 4,824 in 2020. Similarly, Yersinia spp. and most commonly Y. enterocolitica 
caused 6,876 cases of yersiniosis in 2021 compared with 5,747 in 2020, and also 
deaths. The conclusion is that eggs and egg products remain the most dangerous foods 
in epidemics, but several major incidents have been linked to contaminated vegetables 
(especially lettuce), fruits, and sesame seeds. To prove the genetic link, i.e., that the 
bacteria have the same origin in different sick individuals, the entire genome must be 
sequenced. In the suppressing epidemics, food storage and preservation conditions, 
lettuce washing, handling-washing, cleaning and disinfection in food preparation 
areas, and distribution are of particular importance.",
publisher = "Prijedor: Public Institution College of Health Sciences",
journal = "2nd International Conference: Knowledge to Health: SANUS 2023. Book 2, Proceedings; 2023 Jun 23-24; Prijedor, Bosnia and Herzegovina",
title = "Microbiological quality and the most common food contaminants",
doi = "10.7251/ZSAN2302261Z",
pages = "261-270"
}

Zavišić, G., Ristić, S., Petković, B.,& Janković, D.. (2023). Microbiological quality and the most common food contaminants. in 2nd International Conference: Knowledge to Health: SANUS 2023. Book 2, Proceedings; 2023 Jun 23-24; Prijedor, Bosnia and Herzegovina
Prijedor: Public Institution College of Health Sciences., 261-270.
https://doi.org/10.7251/ZSAN2302261Z

Zavišić G, Ristić S, Petković B, Janković D. Microbiological quality and the most common food contaminants. in 2nd International Conference: Knowledge to Health: SANUS 2023. Book 2, Proceedings; 2023 Jun 23-24; Prijedor, Bosnia and Herzegovina. 2023;:261-270.
doi:10.7251/ZSAN2302261Z .

Zavišić, Gordana, Ristić, Slavica, Petković, Branka, Janković, Drina, "Microbiological quality and the most common food contaminants" in 2nd International Conference: Knowledge to Health: SANUS 2023. Book 2, Proceedings; 2023 Jun 23-24; Prijedor, Bosnia and Herzegovina (2023):261-270,
https://doi.org/10.7251/ZSAN2302261Z . .

TY  - CONF
AU  - Janković-Tomanić, Milena
AU  - Vranković, Jelena
AU  - Petković, Branka
AU  - Perić Mataruga, Vesna
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6525
AB  - Tenebrio molitor is considered a pest of stored grains and grain-based products, but also as an important
supplement in animal and human nutrition. It is important to point out that T. molitor larvae are sensitive
to the presence of mycotoxins in the environment, changing the behavior and some biochemical
parameters. Mycotoxin zearalenone (ZEA) was used to assess the effect on the induction of oxidative
stress and behavior in T. molitor larvae. The aim of this research was to examine the effect of high doses
of mycotoxin ZEA (10 and 20 mg/kg) in feed on the activity of the enzymes superoxide dismutase (SOD),
catalase (CAT), and glutathione S-transferase (GST), as well as on the parameters of locomotor activity:
travel distance, time in movement, and average speed while in motion in T. molitor larvae.
The results of this study showed that the presence of ZEA in feed at concentrations of 10 and 20 mg/kg
significantly increased the specific activity of SOD, CAT, and GST. It also affected the locomotor activity
of the larvae, i.e. travel distance and time in movement were significantly lower in larvae exposed to
10 and 20 mg/kg ZEA, while average speed did not change significantly. The presence of ZEA leads to
significant changes in the physiology and behavior of T. molitor larvae and can be useful in the early
detection of food contamination with this dangerous mycotoxin.
AB  - Tenebrio molitor se smatra štetočinom uskladištenih žitarica i proizvoda od žitarica, ali i kao važan
dodatak u ishrani životinja i ljudi. Važno je istaći da su T. molitor larve osetljive na prisustvo mikotoksina
u okruženju, menjajući ponašanje i vrednosti biohemijskih parametara. Fungalni toksin zearalenon
(ZEA) je korišćen za procenu uticaja na oksidativni stres i lokomotornu aktivnost larvi brašnenog crva, T.
molitor. Cilj ovog istraživanja je bio da se ispita uticaj visokih doza mikotoksina ZEA (10 i 20 mg/kg) u hrani
na aktivnost enzima superoksid dismutaze (SOD), katalaze (CAT) i glutation S-transferaze (GST), kao i na
parametre lokomotorne aktivnosti: pređeni put, vreme kretanja i prosečnu brzinu kretanja larvi T. molitor.
Rezultati ovog istraživanja su pokazali da prisustvo ZEA u hrani u koncentracijama od 10 i 20 mg/kg
značajno povećava specifičnu aktivnost SOD, CAT i GST. Takođe, uticalo je i na lokomotornu aktivnost
larvi tj. pređeni put i vreme kretanja su bili značajno niži kod larvi izloženih 10 i 20 mg/kg ZEA, dok se
prosečna brzina kretanja nije značajno menjala.
Prisustvo ZEA dovodi do značajnih promena u fiziologiji i ponašanju larvi T. molitor i može biti korisno
u ranom otkrivanju kontaminacije hrane ovim opasnim mikotoksinom.
PB  - Belgrade: Serbian Society of Toxicology
C3  - Abstract Book: 13th International Congress of the Serbian Society of Toxicology and 1st toxSEE Regional Conference: Present and Future of toxicology: Challenges and opportunities; 2023 May 10-12; Belgrade, Serbia
T1  - The effects of high doses of the mycotoxin zearalenone on Tenebrio molitor L. larvae
T1  - Efekat visokih doza mikotoksina zearalenona na larve brašnenog crva Tenebrio molitor L.
SP  - 87
EP  - 88
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_6525
ER  - 

@conference{
author = "Janković-Tomanić, Milena and Vranković, Jelena and Petković, Branka and Perić Mataruga, Vesna",
year = "2023",
abstract = "Tenebrio molitor is considered a pest of stored grains and grain-based products, but also as an important
supplement in animal and human nutrition. It is important to point out that T. molitor larvae are sensitive
to the presence of mycotoxins in the environment, changing the behavior and some biochemical
parameters. Mycotoxin zearalenone (ZEA) was used to assess the effect on the induction of oxidative
stress and behavior in T. molitor larvae. The aim of this research was to examine the effect of high doses
of mycotoxin ZEA (10 and 20 mg/kg) in feed on the activity of the enzymes superoxide dismutase (SOD),
catalase (CAT), and glutathione S-transferase (GST), as well as on the parameters of locomotor activity:
travel distance, time in movement, and average speed while in motion in T. molitor larvae.
The results of this study showed that the presence of ZEA in feed at concentrations of 10 and 20 mg/kg
significantly increased the specific activity of SOD, CAT, and GST. It also affected the locomotor activity
of the larvae, i.e. travel distance and time in movement were significantly lower in larvae exposed to
10 and 20 mg/kg ZEA, while average speed did not change significantly. The presence of ZEA leads to
significant changes in the physiology and behavior of T. molitor larvae and can be useful in the early
detection of food contamination with this dangerous mycotoxin., Tenebrio molitor se smatra štetočinom uskladištenih žitarica i proizvoda od žitarica, ali i kao važan
dodatak u ishrani životinja i ljudi. Važno je istaći da su T. molitor larve osetljive na prisustvo mikotoksina
u okruženju, menjajući ponašanje i vrednosti biohemijskih parametara. Fungalni toksin zearalenon
(ZEA) je korišćen za procenu uticaja na oksidativni stres i lokomotornu aktivnost larvi brašnenog crva, T.
molitor. Cilj ovog istraživanja je bio da se ispita uticaj visokih doza mikotoksina ZEA (10 i 20 mg/kg) u hrani
na aktivnost enzima superoksid dismutaze (SOD), katalaze (CAT) i glutation S-transferaze (GST), kao i na
parametre lokomotorne aktivnosti: pređeni put, vreme kretanja i prosečnu brzinu kretanja larvi T. molitor.
Rezultati ovog istraživanja su pokazali da prisustvo ZEA u hrani u koncentracijama od 10 i 20 mg/kg
značajno povećava specifičnu aktivnost SOD, CAT i GST. Takođe, uticalo je i na lokomotornu aktivnost
larvi tj. pređeni put i vreme kretanja su bili značajno niži kod larvi izloženih 10 i 20 mg/kg ZEA, dok se
prosečna brzina kretanja nije značajno menjala.
Prisustvo ZEA dovodi do značajnih promena u fiziologiji i ponašanju larvi T. molitor i može biti korisno
u ranom otkrivanju kontaminacije hrane ovim opasnim mikotoksinom.",
publisher = "Belgrade: Serbian Society of Toxicology",
journal = "Abstract Book: 13th International Congress of the Serbian Society of Toxicology and 1st toxSEE Regional Conference: Present and Future of toxicology: Challenges and opportunities; 2023 May 10-12; Belgrade, Serbia",
title = "The effects of high doses of the mycotoxin zearalenone on Tenebrio molitor L. larvae, Efekat visokih doza mikotoksina zearalenona na larve brašnenog crva Tenebrio molitor L.",
pages = "87-88",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_6525"
}

Janković-Tomanić, M., Vranković, J., Petković, B.,& Perić Mataruga, V.. (2023). The effects of high doses of the mycotoxin zearalenone on Tenebrio molitor L. larvae. in Abstract Book: 13th International Congress of the Serbian Society of Toxicology and 1st toxSEE Regional Conference: Present and Future of toxicology: Challenges and opportunities; 2023 May 10-12; Belgrade, Serbia
Belgrade: Serbian Society of Toxicology., 87-88.
https://hdl.handle.net/21.15107/rcub_ibiss_6525

Janković-Tomanić M, Vranković J, Petković B, Perić Mataruga V. The effects of high doses of the mycotoxin zearalenone on Tenebrio molitor L. larvae. in Abstract Book: 13th International Congress of the Serbian Society of Toxicology and 1st toxSEE Regional Conference: Present and Future of toxicology: Challenges and opportunities; 2023 May 10-12; Belgrade, Serbia. 2023;:87-88.
https://hdl.handle.net/21.15107/rcub_ibiss_6525 .

Janković-Tomanić, Milena, Vranković, Jelena, Petković, Branka, Perić Mataruga, Vesna, "The effects of high doses of the mycotoxin zearalenone on Tenebrio molitor L. larvae" in Abstract Book: 13th International Congress of the Serbian Society of Toxicology and 1st toxSEE Regional Conference: Present and Future of toxicology: Challenges and opportunities; 2023 May 10-12; Belgrade, Serbia (2023):87-88,
https://hdl.handle.net/21.15107/rcub_ibiss_6525 .

TY  - JOUR
AU  - Janković Tomanić, Milena
AU  - Petković, Branka
AU  - Vranković, Jelena
AU  - Perić Mataruga, Vesna
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5730
AB  - The larvae of the yellow mealworm Tenebrio molitor represent a new sustainable source of protein and nutrients for animal and human nutrition. To ensure safe insect-based foods, the risks of mycotoxins and other chemicals must be elucidated. Since oxidative stress is known to underlie many mycotoxin-induced disorders, the present work investigates the effects of the mycotoxin zearalenone (ZEA) on the responses of some oxidative stress biomarkers, superoxide dismutase (SOD), catalase (CAT), and glutathione S-transferase (GST) in the whole body of mealworm, as well as the effects on larval survival, body weight, and locomotor activity, and some aspects of mycotoxin accumulation. Larvae were fed artificially contaminated wheat bran containing approximately 0.1 mg/kg, 0.5 mg/kg, 2 mg/kg, and 5 mg/kg ZEA for two weeks. The results of the current study showed that ZEA-contaminated wheat bran at a concentration of 0.5 mg/kg was correlated with increased SOD, CAT, and GST enzyme activities and decreased locomotor activity. Higher concentrations of ZEA, i.e., 2 and 5 mg/kg caused enzymes and locomotor activity to return to control levels. The presence of ZEA in the diet for two weeks did not affect survival but resulted in lower weight gain in T. molitor larvae. The concentration of ZEA in the residual material was 21.1–37.6%, while in the larvae it accounted for 0.38–0.51% of the mycotoxin in the feed. The selected concentrations were in accordance with the EU limits for the presence of ZEA in food and with the levels found in naturally contaminated cereals. Our results suggest that ZEA at the tested concentration induces physiological, biochemical, and behavioral changes in larvae that could potentially serve as early markers of mycotoxin contamination.
PB  - Oxford: Pergamon-Elsevier Science Ltd.
T2  - Journal of Stored Products Research
T1  - Changes in antioxidant enzymes and locomotor activity of yellow mealworm larvae fed the mycotoxin zearalenone supplemented diet
VL  - 102
DO  - 10.1016/j.jspr.2023.102113
SP  - 102113
ER  - 

@article{
author = "Janković Tomanić, Milena and Petković, Branka and Vranković, Jelena and Perić Mataruga, Vesna",
year = "2023",
abstract = "The larvae of the yellow mealworm Tenebrio molitor represent a new sustainable source of protein and nutrients for animal and human nutrition. To ensure safe insect-based foods, the risks of mycotoxins and other chemicals must be elucidated. Since oxidative stress is known to underlie many mycotoxin-induced disorders, the present work investigates the effects of the mycotoxin zearalenone (ZEA) on the responses of some oxidative stress biomarkers, superoxide dismutase (SOD), catalase (CAT), and glutathione S-transferase (GST) in the whole body of mealworm, as well as the effects on larval survival, body weight, and locomotor activity, and some aspects of mycotoxin accumulation. Larvae were fed artificially contaminated wheat bran containing approximately 0.1 mg/kg, 0.5 mg/kg, 2 mg/kg, and 5 mg/kg ZEA for two weeks. The results of the current study showed that ZEA-contaminated wheat bran at a concentration of 0.5 mg/kg was correlated with increased SOD, CAT, and GST enzyme activities and decreased locomotor activity. Higher concentrations of ZEA, i.e., 2 and 5 mg/kg caused enzymes and locomotor activity to return to control levels. The presence of ZEA in the diet for two weeks did not affect survival but resulted in lower weight gain in T. molitor larvae. The concentration of ZEA in the residual material was 21.1–37.6%, while in the larvae it accounted for 0.38–0.51% of the mycotoxin in the feed. The selected concentrations were in accordance with the EU limits for the presence of ZEA in food and with the levels found in naturally contaminated cereals. Our results suggest that ZEA at the tested concentration induces physiological, biochemical, and behavioral changes in larvae that could potentially serve as early markers of mycotoxin contamination.",
publisher = "Oxford: Pergamon-Elsevier Science Ltd.",
journal = "Journal of Stored Products Research",
title = "Changes in antioxidant enzymes and locomotor activity of yellow mealworm larvae fed the mycotoxin zearalenone supplemented diet",
volume = "102",
doi = "10.1016/j.jspr.2023.102113",
pages = "102113"
}

Janković Tomanić, M., Petković, B., Vranković, J.,& Perić Mataruga, V.. (2023). Changes in antioxidant enzymes and locomotor activity of yellow mealworm larvae fed the mycotoxin zearalenone supplemented diet. in Journal of Stored Products Research
Oxford: Pergamon-Elsevier Science Ltd.., 102, 102113.
https://doi.org/10.1016/j.jspr.2023.102113

Janković Tomanić M, Petković B, Vranković J, Perić Mataruga V. Changes in antioxidant enzymes and locomotor activity of yellow mealworm larvae fed the mycotoxin zearalenone supplemented diet. in Journal of Stored Products Research. 2023;102:102113.
doi:10.1016/j.jspr.2023.102113 .

Janković Tomanić, Milena, Petković, Branka, Vranković, Jelena, Perić Mataruga, Vesna, "Changes in antioxidant enzymes and locomotor activity of yellow mealworm larvae fed the mycotoxin zearalenone supplemented diet" in Journal of Stored Products Research, 102 (2023):102113,
https://doi.org/10.1016/j.jspr.2023.102113 . .

TY  - CONF
AU  - Podgorac, Jelena
AU  - Petković, Branka
PY  - 2023
UR  - https://www.rad-conference.org/RAD_2023-Book_of_Abstracts.pdf
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6283
AB  - Introduction: Treatment of epilepsy always has an individual and unique path. Despite effective 
classical and novel antiepileptic drugs (AEDs), monotherapy is limited and insufficient in some cases, such as 
refractory epilepsy. Pregnant women with epilepsy are a population that requires a special approach. Protocol 
guidelines and experience dictate the rational use of AEDs during pregnancy, which means that monotherapy 
and the lowest therapeutic (curable) dose should be used. Epilepsy as a multifactorial condition involving 
different categories of epileptic disorders sometimes requires treatment with highly potent therapeutic drugs, 
such as valproic acid (VPA), which is known to be teratogenic. In some cases, not only can it not be 
substituted, but it must also be combined with another drug. The combination of VPA and levetiracetam 
(LEV), at a dosage of 1:1, achieves additive efficacy with no evidence of toxicity.
Aim: Thus, the aim of the present study was to investigate the sensorimotor development of mice whose 
mothers were treated with a combination of VPA and LEV (1:1 ratio) during breeding and gestation.
Method: Adult, 8-week-old female NMRI mice were used in this study. Two groups of animals were 
formed: one group (8 females) treated with a combination of LEV at a dose of 211 mg/kg/day (LEV-211) and 
VPA at a dose of 200 mg/kg/day (VPA-200), and a control group (8 females) receiving an equivalent amount 
of saline. The doses administered correspond to human doses of 1000 mg/day for both antiepileptic drugs. 
All animals were treated subcutaneously into the loose skin on the back of the neck twice daily. Treatment 
was initiated at the mating of males and females and continued throughout the entire period of breeding and 
gestation. After the females gave birth, each of them was housed separately with her litter. Offspring were 
separated by sex on postnatal day (PND) 21. Sensorimotor system performance and conditional learning 
were assessed on PND25 and PND32 in the hot plate test (HPT).
Results: Female and male offspring treated prenatally with a combination of AEDs (LEV-211 + VPA 200) showed a significantly faster response than the control group on PND32, whereas female offspring also 
showed a faster response than the control group on the first day of testing, PND25.
Conclusion: Considering the results of the HPT and the different sensorimotor responses in offspring 
prenatally treated with antiepileptic drug combinations in animal models, it would be necessary for the 
human practice to continuously monitor (until the end of adolescence) the children prenatally exposed to this 
antiepileptic drug therapy.
PB  - Niš, Serbia: RAD Centre
C3  - Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro
T1  - Prenatal exposure to an antiepileptic combination  (levetiracetam and valproic acid) throughout gestation  and postnatal sensorimotor development in mice
DO  - 10.21175/rad.abstr.book.2023.6.8
SP  - 29
ER  - 

@conference{
author = "Podgorac, Jelena and Petković, Branka",
year = "2023",
abstract = "Introduction: Treatment of epilepsy always has an individual and unique path. Despite effective 
classical and novel antiepileptic drugs (AEDs), monotherapy is limited and insufficient in some cases, such as 
refractory epilepsy. Pregnant women with epilepsy are a population that requires a special approach. Protocol 
guidelines and experience dictate the rational use of AEDs during pregnancy, which means that monotherapy 
and the lowest therapeutic (curable) dose should be used. Epilepsy as a multifactorial condition involving 
different categories of epileptic disorders sometimes requires treatment with highly potent therapeutic drugs, 
such as valproic acid (VPA), which is known to be teratogenic. In some cases, not only can it not be 
substituted, but it must also be combined with another drug. The combination of VPA and levetiracetam 
(LEV), at a dosage of 1:1, achieves additive efficacy with no evidence of toxicity.
Aim: Thus, the aim of the present study was to investigate the sensorimotor development of mice whose 
mothers were treated with a combination of VPA and LEV (1:1 ratio) during breeding and gestation.
Method: Adult, 8-week-old female NMRI mice were used in this study. Two groups of animals were 
formed: one group (8 females) treated with a combination of LEV at a dose of 211 mg/kg/day (LEV-211) and 
VPA at a dose of 200 mg/kg/day (VPA-200), and a control group (8 females) receiving an equivalent amount 
of saline. The doses administered correspond to human doses of 1000 mg/day for both antiepileptic drugs. 
All animals were treated subcutaneously into the loose skin on the back of the neck twice daily. Treatment 
was initiated at the mating of males and females and continued throughout the entire period of breeding and 
gestation. After the females gave birth, each of them was housed separately with her litter. Offspring were 
separated by sex on postnatal day (PND) 21. Sensorimotor system performance and conditional learning 
were assessed on PND25 and PND32 in the hot plate test (HPT).
Results: Female and male offspring treated prenatally with a combination of AEDs (LEV-211 + VPA 200) showed a significantly faster response than the control group on PND32, whereas female offspring also 
showed a faster response than the control group on the first day of testing, PND25.
Conclusion: Considering the results of the HPT and the different sensorimotor responses in offspring 
prenatally treated with antiepileptic drug combinations in animal models, it would be necessary for the 
human practice to continuously monitor (until the end of adolescence) the children prenatally exposed to this 
antiepileptic drug therapy.",
publisher = "Niš, Serbia: RAD Centre",
journal = "Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro",
title = "Prenatal exposure to an antiepileptic combination  (levetiracetam and valproic acid) throughout gestation  and postnatal sensorimotor development in mice",
doi = "10.21175/rad.abstr.book.2023.6.8",
pages = "29"
}

Podgorac, J.,& Petković, B.. (2023). Prenatal exposure to an antiepileptic combination  (levetiracetam and valproic acid) throughout gestation  and postnatal sensorimotor development in mice. in Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro
Niš, Serbia: RAD Centre., 29.
https://doi.org/10.21175/rad.abstr.book.2023.6.8

Podgorac J, Petković B. Prenatal exposure to an antiepileptic combination  (levetiracetam and valproic acid) throughout gestation  and postnatal sensorimotor development in mice. in Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro. 2023;:29.
doi:10.21175/rad.abstr.book.2023.6.8 .

Podgorac, Jelena, Petković, Branka, "Prenatal exposure to an antiepileptic combination  (levetiracetam and valproic acid) throughout gestation  and postnatal sensorimotor development in mice" in Book of Abstracts: Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology: RAD 2023; 2023 Jun 19-23; Herceg Novi, Montenegro (2023):29,
https://doi.org/10.21175/rad.abstr.book.2023.6.8 . .

TY  - JOUR
AU  - Sekulić, Slobodan
AU  - Stilinović, Nebojša
AU  - Baturan, Branislava
AU  - Krsman, Anita
AU  - Tešić, Igor
AU  - Vejnović, Aleksandra
AU  - Petrović, Đorđe
AU  - Nikolašević, Željka
AU  - Mijavec, Anna
AU  - Pešić, Vesna
AU  - Petković, Branka
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6057
AB  - Background: Breech presentation (BP) results from at random filling of the intrauterine cavity, with an equal probability for a BP or cephalic presentation (CP). Each fetus in BP has its "pair" in CP randomly assumed CP. Direct comparison of BP and CP makes bias to less expressed differences between these two groups. It is therefore necessary to subtract the number of fetuses/newborns from the CP set that are identical to the number of fetuses/newborns in the BP set, with identical characteristics, and add this group to the BP set before comparing them to the rest of the CP fetuses/newborns in the matching process. Methods: The procedure encompasses nine variables in pregnancies with a congenitally malformed uterus (CMU) identified at the Department of Obstetrics (1985-2014): gestational age, birth mass, birth length, head circumference, shoulders circumference, umbilical length, placental weight, newborn mass/newborn length ratio, and newborn mass/placental mass ratio. Firstly, the probability of BP was determined and its relation to gestational age, physical characteristics, and previous presentations. Then direct comparison as well as case-control matching of the CP and BP were performed. Case-control matching was based on either a single specific variable (M1) or all combined variables (M2). Findings: 462 deliveries were identified with CMU. In 81 cases of multiparity, a fetal presentation was found to be an independent event regardless of the previous presentation, gestational age, and newborn physical characteristics. In four types of CMU with 337 deliveries (Bicornuate, Didelphys, Unicornuate, Arcuate), 9 variables with 36 instances of comparison were observed. M1 in 10 instances and M2 in 6 instances showed a statistically significant lower value of breech/random presentation compared with CP. CP have lower value in 2 instances in M1 and 1 in M2. Statistically significant differences were absent without the matching process. Interpretations: The study confirms the maximum probability for the BP is 50%. The case-control matching procedure shows that it is able to detect the difference between the breech/random presentation and CP, while the classic method of direct comparison was unable to detect any differences. The outcome of the breech/random presentation in CMU should be evaluated with the described case-control matching procedure.
PB  - Lausanne: Frontiers Media SA
T2  - Frontiers in Medicine
T1  - Corrected evaluation of the breech presentation outcome based on etiology of this presentation in congenitally malformed uterus
VL  - 10
DO  - 10.3389/fmed.2023.1160229
SP  - 1160229
ER  - 

@article{
author = "Sekulić, Slobodan and Stilinović, Nebojša and Baturan, Branislava and Krsman, Anita and Tešić, Igor and Vejnović, Aleksandra and Petrović, Đorđe and Nikolašević, Željka and Mijavec, Anna and Pešić, Vesna and Petković, Branka",
year = "2023",
abstract = "Background: Breech presentation (BP) results from at random filling of the intrauterine cavity, with an equal probability for a BP or cephalic presentation (CP). Each fetus in BP has its "pair" in CP randomly assumed CP. Direct comparison of BP and CP makes bias to less expressed differences between these two groups. It is therefore necessary to subtract the number of fetuses/newborns from the CP set that are identical to the number of fetuses/newborns in the BP set, with identical characteristics, and add this group to the BP set before comparing them to the rest of the CP fetuses/newborns in the matching process. Methods: The procedure encompasses nine variables in pregnancies with a congenitally malformed uterus (CMU) identified at the Department of Obstetrics (1985-2014): gestational age, birth mass, birth length, head circumference, shoulders circumference, umbilical length, placental weight, newborn mass/newborn length ratio, and newborn mass/placental mass ratio. Firstly, the probability of BP was determined and its relation to gestational age, physical characteristics, and previous presentations. Then direct comparison as well as case-control matching of the CP and BP were performed. Case-control matching was based on either a single specific variable (M1) or all combined variables (M2). Findings: 462 deliveries were identified with CMU. In 81 cases of multiparity, a fetal presentation was found to be an independent event regardless of the previous presentation, gestational age, and newborn physical characteristics. In four types of CMU with 337 deliveries (Bicornuate, Didelphys, Unicornuate, Arcuate), 9 variables with 36 instances of comparison were observed. M1 in 10 instances and M2 in 6 instances showed a statistically significant lower value of breech/random presentation compared with CP. CP have lower value in 2 instances in M1 and 1 in M2. Statistically significant differences were absent without the matching process. Interpretations: The study confirms the maximum probability for the BP is 50%. The case-control matching procedure shows that it is able to detect the difference between the breech/random presentation and CP, while the classic method of direct comparison was unable to detect any differences. The outcome of the breech/random presentation in CMU should be evaluated with the described case-control matching procedure.",
publisher = "Lausanne: Frontiers Media SA",
journal = "Frontiers in Medicine",
title = "Corrected evaluation of the breech presentation outcome based on etiology of this presentation in congenitally malformed uterus",
volume = "10",
doi = "10.3389/fmed.2023.1160229",
pages = "1160229"
}

Sekulić, S., Stilinović, N., Baturan, B., Krsman, A., Tešić, I., Vejnović, A., Petrović, Đ., Nikolašević, Ž., Mijavec, A., Pešić, V.,& Petković, B.. (2023). Corrected evaluation of the breech presentation outcome based on etiology of this presentation in congenitally malformed uterus. in Frontiers in Medicine
Lausanne: Frontiers Media SA., 10, 1160229.
https://doi.org/10.3389/fmed.2023.1160229

Sekulić S, Stilinović N, Baturan B, Krsman A, Tešić I, Vejnović A, Petrović Đ, Nikolašević Ž, Mijavec A, Pešić V, Petković B. Corrected evaluation of the breech presentation outcome based on etiology of this presentation in congenitally malformed uterus. in Frontiers in Medicine. 2023;10:1160229.
doi:10.3389/fmed.2023.1160229 .

Sekulić, Slobodan, Stilinović, Nebojša, Baturan, Branislava, Krsman, Anita, Tešić, Igor, Vejnović, Aleksandra, Petrović, Đorđe, Nikolašević, Željka, Mijavec, Anna, Pešić, Vesna, Petković, Branka, "Corrected evaluation of the breech presentation outcome based on etiology of this presentation in congenitally malformed uterus" in Frontiers in Medicine, 10 (2023):1160229,
https://doi.org/10.3389/fmed.2023.1160229 . .

TY  - CONF
AU  - Kesić, Srđan
AU  - Stojadinović, Gordana
AU  - Martać, Ljiljana
AU  - Sekulić, Slobodan
AU  - Petković, Branka
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5834
AB  - MK-801 can mimic the cognitive, negative, psychotic, and physiological features of
schizophrenia, including increased hyperlocomotion and altered behavioral flexibility.
As N-methyl-D-aspartate (NMDA) receptor antagonist, it is widely used to test the
“glutamate hypofunction hypothesis of schizophrenia”. An extremely low-frequency
magnetic field (ELF-MF) can stimulate NMDA receptor activity, but its effect on
dysregulated glutamine transmission is unknown. Therefore, this study addresses the
effect of continuous exposure to ELF-MF (50 Hz, 0.5 mT) for 7 days on rat
psychomotor behavior induced by acute administration of MK-801 (0.25 mg/kg, i.p.).
During the experiment, adult male Wistar rats were placed near the on/off generator of
ELF-MF, injected with MK-801/saline immediately after 7-day sham/ELF-MF
exposure, and subjected to the open field test for 2 hours. Their behavior was analyzed
using the ANY-maze software and expressed as travel distance, time in movement,
and average speed while in motion in 30-min intervals. The results show that (1) acute
administration of 0.25 mg/kg MK-801 significantly increased travel distance and time
in movement from 60 to 120 min and average speed while in motion from 60 to 90
min compared with saline-injected animals; (2) 7-day exposure to ELF-MF had no
significant effect on the behavior of saline- and MK-801-injected animals compared
with the corresponding controls. Therefore, it can be concluded that this regime of
ELF-MF exposure does not affect the psychomotor behavior of rats caused by the
pharmacological modification of glutamine transmission with the applied MK-801
dose.
PB  - Belgrade: Serbian Neuroscience Society
C3  - Book of abstracts: 8th Congress of Serbian Neuroscience Society with international participation; 2023 May 31 - Jun 2; Belgrade, Serbia
T1  - Effect of ELF-MF (50 Hz, 0.5 mT) on psychomotor behavior of rats caused by acute administration of MK-801
SP  - 50
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5834
ER  - 

@conference{
author = "Kesić, Srđan and Stojadinović, Gordana and Martać, Ljiljana and Sekulić, Slobodan and Petković, Branka",
year = "2023",
abstract = "MK-801 can mimic the cognitive, negative, psychotic, and physiological features of
schizophrenia, including increased hyperlocomotion and altered behavioral flexibility.
As N-methyl-D-aspartate (NMDA) receptor antagonist, it is widely used to test the
“glutamate hypofunction hypothesis of schizophrenia”. An extremely low-frequency
magnetic field (ELF-MF) can stimulate NMDA receptor activity, but its effect on
dysregulated glutamine transmission is unknown. Therefore, this study addresses the
effect of continuous exposure to ELF-MF (50 Hz, 0.5 mT) for 7 days on rat
psychomotor behavior induced by acute administration of MK-801 (0.25 mg/kg, i.p.).
During the experiment, adult male Wistar rats were placed near the on/off generator of
ELF-MF, injected with MK-801/saline immediately after 7-day sham/ELF-MF
exposure, and subjected to the open field test for 2 hours. Their behavior was analyzed
using the ANY-maze software and expressed as travel distance, time in movement,
and average speed while in motion in 30-min intervals. The results show that (1) acute
administration of 0.25 mg/kg MK-801 significantly increased travel distance and time
in movement from 60 to 120 min and average speed while in motion from 60 to 90
min compared with saline-injected animals; (2) 7-day exposure to ELF-MF had no
significant effect on the behavior of saline- and MK-801-injected animals compared
with the corresponding controls. Therefore, it can be concluded that this regime of
ELF-MF exposure does not affect the psychomotor behavior of rats caused by the
pharmacological modification of glutamine transmission with the applied MK-801
dose.",
publisher = "Belgrade: Serbian Neuroscience Society",
journal = "Book of abstracts: 8th Congress of Serbian Neuroscience Society with international participation; 2023 May 31 - Jun 2; Belgrade, Serbia",
title = "Effect of ELF-MF (50 Hz, 0.5 mT) on psychomotor behavior of rats caused by acute administration of MK-801",
pages = "50",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5834"
}

Kesić, S., Stojadinović, G., Martać, L., Sekulić, S.,& Petković, B.. (2023). Effect of ELF-MF (50 Hz, 0.5 mT) on psychomotor behavior of rats caused by acute administration of MK-801. in Book of abstracts: 8th Congress of Serbian Neuroscience Society with international participation; 2023 May 31 - Jun 2; Belgrade, Serbia
Belgrade: Serbian Neuroscience Society., 50.
https://hdl.handle.net/21.15107/rcub_ibiss_5834

Kesić S, Stojadinović G, Martać L, Sekulić S, Petković B. Effect of ELF-MF (50 Hz, 0.5 mT) on psychomotor behavior of rats caused by acute administration of MK-801. in Book of abstracts: 8th Congress of Serbian Neuroscience Society with international participation; 2023 May 31 - Jun 2; Belgrade, Serbia. 2023;:50.
https://hdl.handle.net/21.15107/rcub_ibiss_5834 .

Kesić, Srđan, Stojadinović, Gordana, Martać, Ljiljana, Sekulić, Slobodan, Petković, Branka, "Effect of ELF-MF (50 Hz, 0.5 mT) on psychomotor behavior of rats caused by acute administration of MK-801" in Book of abstracts: 8th Congress of Serbian Neuroscience Society with international participation; 2023 May 31 - Jun 2; Belgrade, Serbia (2023):50,
https://hdl.handle.net/21.15107/rcub_ibiss_5834 .

TY  - JOUR
AU  - Zavišić, Gordana
AU  - Ristić, Slavica
AU  - Petković, Branka
AU  - Živkov Šaponja, Dragoslava
AU  - Jojić, Nikola
AU  - Janković, Drina
PY  - 2023
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5752
AB  - Microorganisms used as probiotics should meet elementary safety aspects (non-toxicity, absence of antibiotic resistance genes and translocation) and functional/technological aspects (resistance and survival in the acid gastric environment, adhesiveness, stability, and cell viability). Probiotics with the health claim of being a dietary product or a pharmabiotic (drug category) should be clinically tested, validated, documented, and continuously controlled for quality. Important quality parameters include the identification of declared probiotic strains, the number of viable microorganisms (probiotic bacteria and/or fungi), and microbiological purity (absence of specified pathogenic/opportunistic pathogenic bacteria and fungi, and limitation of total unspecified contaminants such as aerobic bacteria, yeasts, and molds). Due to numerous reports of low-quality commercial probiotics marketed for human use, this review discusses the methods used to test the
probiotic microorganism content, safety for the intended use, and proven health benefits of those probiotics whose microbiological quality deviates from the manufacturer’s stated content, as well as the maintenance of cell viability, i.e., stability of the probiotic during the shelf life. In addition, the adverse effects of probiotics and the potential hazards to the health of the user are addressed.
AB  - Mikroorganizmi koji se koriste kao probiotici treba da zadovolje elementarne aspekte
bezbednosti (netoksičnost, odsustvo gena rezistencije na antibiotike i translokacije) i
funkcionalne/tehnološke aspekte (otpornost i preživljavanje u kiselom gastričnom okruženju, adhezivnost, stabilnost i vijabilnost ćelija). Probiotici sa zdravstvenom tvrdnjom, bilo da su
dijetetski proizvod ili farmabiotik (kategorija lekova), treba da budu klinički testirani, validirani,
dokumentovani i stalno kontrolisani u pogledu kvaliteta. Važni parametri kvaliteta su
identifikacija deklarisanih probiotičkih sojeva, broj živih mikroorganizama (probiotičke bakterije i/ili gljivice) i mikrobiološka čistoća (odsustvo specifičnih patogenih/uslovno patogenih bakterija i gljivica, kao i ograničavanje ukupnog broja kontaminanata kao što su aerobne bakterije, kvasci i plesni). Zbog brojnih izveštaja o komercijalnim probioticima niskog kvaliteta koji se prodaju za ljudsku upotrebu, ovaj pregled razmatra metode koje se koriste za testiranje sadržaja probiotičkih mikroorganizama, bezbednost za nameravanu upotrebu i dokazane zdravstvene koristi onih probiotika čiji mikrobiološki kvalitet odstupa od sadržaja koji tvrde proizvođači i održavanja vitalnosti ćelija, tj. stabilnosti probiotika tokom roka trajanja. Pored toga, razmatraju se i neželjeni efekti probiotika i potencijalne opasnosti po zdravlje korisnika.
PB  - Belgrade: Pharmaceutical Association of Serbia
T2  - Arhiv za Farmaciju
T1  - Microbiological Quality of Probiotic Products
T1  - Mikrobiološki kvalitet probiotičkih proizvoda
IS  - 1
VL  - 73
DO  - 10.5937/arhfarm73-42160
SP  - 17
EP  - 34
ER  - 

@article{
author = "Zavišić, Gordana and Ristić, Slavica and Petković, Branka and Živkov Šaponja, Dragoslava and Jojić, Nikola and Janković, Drina",
year = "2023",
abstract = "Microorganisms used as probiotics should meet elementary safety aspects (non-toxicity, absence of antibiotic resistance genes and translocation) and functional/technological aspects (resistance and survival in the acid gastric environment, adhesiveness, stability, and cell viability). Probiotics with the health claim of being a dietary product or a pharmabiotic (drug category) should be clinically tested, validated, documented, and continuously controlled for quality. Important quality parameters include the identification of declared probiotic strains, the number of viable microorganisms (probiotic bacteria and/or fungi), and microbiological purity (absence of specified pathogenic/opportunistic pathogenic bacteria and fungi, and limitation of total unspecified contaminants such as aerobic bacteria, yeasts, and molds). Due to numerous reports of low-quality commercial probiotics marketed for human use, this review discusses the methods used to test the
probiotic microorganism content, safety for the intended use, and proven health benefits of those probiotics whose microbiological quality deviates from the manufacturer’s stated content, as well as the maintenance of cell viability, i.e., stability of the probiotic during the shelf life. In addition, the adverse effects of probiotics and the potential hazards to the health of the user are addressed., Mikroorganizmi koji se koriste kao probiotici treba da zadovolje elementarne aspekte
bezbednosti (netoksičnost, odsustvo gena rezistencije na antibiotike i translokacije) i
funkcionalne/tehnološke aspekte (otpornost i preživljavanje u kiselom gastričnom okruženju, adhezivnost, stabilnost i vijabilnost ćelija). Probiotici sa zdravstvenom tvrdnjom, bilo da su
dijetetski proizvod ili farmabiotik (kategorija lekova), treba da budu klinički testirani, validirani,
dokumentovani i stalno kontrolisani u pogledu kvaliteta. Važni parametri kvaliteta su
identifikacija deklarisanih probiotičkih sojeva, broj živih mikroorganizama (probiotičke bakterije i/ili gljivice) i mikrobiološka čistoća (odsustvo specifičnih patogenih/uslovno patogenih bakterija i gljivica, kao i ograničavanje ukupnog broja kontaminanata kao što su aerobne bakterije, kvasci i plesni). Zbog brojnih izveštaja o komercijalnim probioticima niskog kvaliteta koji se prodaju za ljudsku upotrebu, ovaj pregled razmatra metode koje se koriste za testiranje sadržaja probiotičkih mikroorganizama, bezbednost za nameravanu upotrebu i dokazane zdravstvene koristi onih probiotika čiji mikrobiološki kvalitet odstupa od sadržaja koji tvrde proizvođači i održavanja vitalnosti ćelija, tj. stabilnosti probiotika tokom roka trajanja. Pored toga, razmatraju se i neželjeni efekti probiotika i potencijalne opasnosti po zdravlje korisnika.",
publisher = "Belgrade: Pharmaceutical Association of Serbia",
journal = "Arhiv za Farmaciju",
title = "Microbiological Quality of Probiotic Products, Mikrobiološki kvalitet probiotičkih proizvoda",
number = "1",
volume = "73",
doi = "10.5937/arhfarm73-42160",
pages = "17-34"
}

Zavišić, G., Ristić, S., Petković, B., Živkov Šaponja, D., Jojić, N.,& Janković, D.. (2023). Microbiological Quality of Probiotic Products. in Arhiv za Farmaciju
Belgrade: Pharmaceutical Association of Serbia., 73(1), 17-34.
https://doi.org/10.5937/arhfarm73-42160

Zavišić G, Ristić S, Petković B, Živkov Šaponja D, Jojić N, Janković D. Microbiological Quality of Probiotic Products. in Arhiv za Farmaciju. 2023;73(1):17-34.
doi:10.5937/arhfarm73-42160 .

Zavišić, Gordana, Ristić, Slavica, Petković, Branka, Živkov Šaponja, Dragoslava, Jojić, Nikola, Janković, Drina, "Microbiological Quality of Probiotic Products" in Arhiv za Farmaciju, 73, no. 1 (2023):17-34,
https://doi.org/10.5937/arhfarm73-42160 . .

TY  - JOUR
AU  - Podgorac, Jelena
AU  - Sekulić, Slobodan
AU  - Petković, Branka
AU  - Stojadinović, Gordana
AU  - Martać, Ljiljana
AU  - Pešić, Vesna
PY  - 2022
UR  - http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC9557044
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5169
AB  - Clinical findings show that the use of valproic acid (VPA) during pregnancy increases the risk of birth defects and autism spectrum disorder in offspring. Although there is a consensus that monitoring of potential long-term outcomes of VPA exposure is needed, especially in undiagnosed individuals, preclinical studies addressing this issue are rare. The present study examined the effects of continuous intrauterine exposure to a wide dose range of VPA (50, 100, 200, and 400 mg/kg/day) on the physical and behavioral response in peripubertal mice as a rodent model of adolescence. Body weight and the hot plate test [on postnatal days (PND) 25 and 32], the elevated plus-maze test (on PND35), and the open field test (on PND40) served to examine physical growth, the supraspinal reflex response to a painful thermal stimulus and conditional learning, anxiety-like/risk-assessment behavior, as well as novelty-induced psychomotor activity, respectively. VPA exposure produced the following responses: (i) a negative effect on body weight, except for the dose of 100 mg/kg/day in both sexes; (ii) an increase in the percentage of animals that responded to the thermal stimulus above the defined cut-off time interval and the response latency in both sexes; (iii) dose-specific changes within sexes in behavior provoked by a novel anxiogenic environment, i.e., in females less anxiety-like/risk-assessment behavior in response to the lowest exposure dose, and in males more pronounced anxiety-like/risk-assessment behavior after exposure to the highest dose and 100 mg/kg/day; (iv) dose-specific changes within sexes in novelty-induced psychomotor activity, i.e., in females a decrease in stereotypy-like activity along with an increase in rearing, and in males a decrease in stereotypy-like activity only. These findings show that continuous intrauterine exposure to VPA produces maladaptive functioning in different behavioral domains in adolescence and that the consequences are delicate to assess as they are dose-related within sexes.
PB  - Lausanne: Frontiers Media S.A.
T2  - Frontiers in Behavioral Neuroscience
T1  - The influence of continuous prenatal exposure to valproic acid on physical, nociceptive, emotional and psychomotor responses during adolescence in mice: Dose-related effects within sexes
VL  - 16
DO  - 10.3389/fnbeh.2022.982811
SP  - 982811
ER  - 

@article{
author = "Podgorac, Jelena and Sekulić, Slobodan and Petković, Branka and Stojadinović, Gordana and Martać, Ljiljana and Pešić, Vesna",
year = "2022",
abstract = "Clinical findings show that the use of valproic acid (VPA) during pregnancy increases the risk of birth defects and autism spectrum disorder in offspring. Although there is a consensus that monitoring of potential long-term outcomes of VPA exposure is needed, especially in undiagnosed individuals, preclinical studies addressing this issue are rare. The present study examined the effects of continuous intrauterine exposure to a wide dose range of VPA (50, 100, 200, and 400 mg/kg/day) on the physical and behavioral response in peripubertal mice as a rodent model of adolescence. Body weight and the hot plate test [on postnatal days (PND) 25 and 32], the elevated plus-maze test (on PND35), and the open field test (on PND40) served to examine physical growth, the supraspinal reflex response to a painful thermal stimulus and conditional learning, anxiety-like/risk-assessment behavior, as well as novelty-induced psychomotor activity, respectively. VPA exposure produced the following responses: (i) a negative effect on body weight, except for the dose of 100 mg/kg/day in both sexes; (ii) an increase in the percentage of animals that responded to the thermal stimulus above the defined cut-off time interval and the response latency in both sexes; (iii) dose-specific changes within sexes in behavior provoked by a novel anxiogenic environment, i.e., in females less anxiety-like/risk-assessment behavior in response to the lowest exposure dose, and in males more pronounced anxiety-like/risk-assessment behavior after exposure to the highest dose and 100 mg/kg/day; (iv) dose-specific changes within sexes in novelty-induced psychomotor activity, i.e., in females a decrease in stereotypy-like activity along with an increase in rearing, and in males a decrease in stereotypy-like activity only. These findings show that continuous intrauterine exposure to VPA produces maladaptive functioning in different behavioral domains in adolescence and that the consequences are delicate to assess as they are dose-related within sexes.",
publisher = "Lausanne: Frontiers Media S.A.",
journal = "Frontiers in Behavioral Neuroscience",
title = "The influence of continuous prenatal exposure to valproic acid on physical, nociceptive, emotional and psychomotor responses during adolescence in mice: Dose-related effects within sexes",
volume = "16",
doi = "10.3389/fnbeh.2022.982811",
pages = "982811"
}

Podgorac, J., Sekulić, S., Petković, B., Stojadinović, G., Martać, L.,& Pešić, V.. (2022). The influence of continuous prenatal exposure to valproic acid on physical, nociceptive, emotional and psychomotor responses during adolescence in mice: Dose-related effects within sexes. in Frontiers in Behavioral Neuroscience
Lausanne: Frontiers Media S.A.., 16, 982811.
https://doi.org/10.3389/fnbeh.2022.982811

Podgorac J, Sekulić S, Petković B, Stojadinović G, Martać L, Pešić V. The influence of continuous prenatal exposure to valproic acid on physical, nociceptive, emotional and psychomotor responses during adolescence in mice: Dose-related effects within sexes. in Frontiers in Behavioral Neuroscience. 2022;16:982811.
doi:10.3389/fnbeh.2022.982811 .

Podgorac, Jelena, Sekulić, Slobodan, Petković, Branka, Stojadinović, Gordana, Martać, Ljiljana, Pešić, Vesna, "The influence of continuous prenatal exposure to valproic acid on physical, nociceptive, emotional and psychomotor responses during adolescence in mice: Dose-related effects within sexes" in Frontiers in Behavioral Neuroscience, 16 (2022):982811,
https://doi.org/10.3389/fnbeh.2022.982811 . .

TY  - JOUR
AU  - Zavišić, Gordana
AU  - Ristić, Slavica
AU  - Rikalović, Milena
AU  - Petković, Branka
AU  - Janković, Drina
AU  - Vukadinović, Aleksandar
AU  - Petričević, Saša
PY  - 2022
UR  - https://linkinghub.elsevier.com/retrieve/pii/S1756464622002377
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5091
AB  - The present study aimed to examine the effect of Lactobacillus rhamnosus Rosell 11 and Lactobacillus helveticus Rosell 52 on glucose (blood level and tolerance), lipids (cholesterol and triglycerides), transaminases (AST and ALT), ALP, urea, and creatinine, along with body weight, food intake, liquid consumption, and gross pathology in a mouse model of metabolic syndrome. Male C57BL/6J mice were fed a high-fat high-sucrose diet and treated by oral gavage with a probiotic mixture in three different concentrations (107, 108, and 109 CFU/mL) once daily for 2 months. Probiotic supplementation, particularly at a concentration of 109 CFU, significantly decreased blood glucose and serum triglyceride levels, improved glucose tolerance, and promoted body weight loss in mice fed a high-fat high-sucrose diet. According to the obtained results, probiotic supplementation is useful for controlling glucose and triglyceride levels and could be used as an adjunctive therapeutic approach in patients with metabolic syndrome. © 2022
PB  - Amsterdam: Elsevier
T2  - Journal of Functional Foods
T1  - Beneficial effects of probiotic supplementation on glucose and triglycerides in a mouse model of metabolic syndrome
VL  - 95
DO  - 10.1016/j.jff.2022.105167
SP  - 105167
ER  - 

@article{
author = "Zavišić, Gordana and Ristić, Slavica and Rikalović, Milena and Petković, Branka and Janković, Drina and Vukadinović, Aleksandar and Petričević, Saša",
year = "2022",
abstract = "The present study aimed to examine the effect of Lactobacillus rhamnosus Rosell 11 and Lactobacillus helveticus Rosell 52 on glucose (blood level and tolerance), lipids (cholesterol and triglycerides), transaminases (AST and ALT), ALP, urea, and creatinine, along with body weight, food intake, liquid consumption, and gross pathology in a mouse model of metabolic syndrome. Male C57BL/6J mice were fed a high-fat high-sucrose diet and treated by oral gavage with a probiotic mixture in three different concentrations (107, 108, and 109 CFU/mL) once daily for 2 months. Probiotic supplementation, particularly at a concentration of 109 CFU, significantly decreased blood glucose and serum triglyceride levels, improved glucose tolerance, and promoted body weight loss in mice fed a high-fat high-sucrose diet. According to the obtained results, probiotic supplementation is useful for controlling glucose and triglyceride levels and could be used as an adjunctive therapeutic approach in patients with metabolic syndrome. © 2022",
publisher = "Amsterdam: Elsevier",
journal = "Journal of Functional Foods",
title = "Beneficial effects of probiotic supplementation on glucose and triglycerides in a mouse model of metabolic syndrome",
volume = "95",
doi = "10.1016/j.jff.2022.105167",
pages = "105167"
}

Zavišić, G., Ristić, S., Rikalović, M., Petković, B., Janković, D., Vukadinović, A.,& Petričević, S.. (2022). Beneficial effects of probiotic supplementation on glucose and triglycerides in a mouse model of metabolic syndrome. in Journal of Functional Foods
Amsterdam: Elsevier., 95, 105167.
https://doi.org/10.1016/j.jff.2022.105167

Zavišić G, Ristić S, Rikalović M, Petković B, Janković D, Vukadinović A, Petričević S. Beneficial effects of probiotic supplementation on glucose and triglycerides in a mouse model of metabolic syndrome. in Journal of Functional Foods. 2022;95:105167.
doi:10.1016/j.jff.2022.105167 .

Zavišić, Gordana, Ristić, Slavica, Rikalović, Milena, Petković, Branka, Janković, Drina, Vukadinović, Aleksandar, Petričević, Saša, "Beneficial effects of probiotic supplementation on glucose and triglycerides in a mouse model of metabolic syndrome" in Journal of Functional Foods, 95 (2022):105167,
https://doi.org/10.1016/j.jff.2022.105167 . .

TY  - JOUR
AU  - Sekulić, Slobodan
AU  - Jovanović, Aleksandar
AU  - Živanović, Željko
AU  - Simić, Svetlana
AU  - Kesić, Srđan
AU  - Petković, Branka
AU  - Čapo, Ivan
AU  - van Loon, Jack J
PY  - 2022
UR  - https://linkinghub.elsevier.com/retrieve/pii/S2214552422000153
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4958
AB  - The International Space Station (ISS) has the possibility to perform experiments regarding rodent reproduction in microgravity. The musculoskeletal system at birth in precocial rodent species more resembles the human than that of altricial rodent species. For precocial rodent species with body weight ≤ 500 g (limit of ISS) determined were: adult body mass, newborn body mass, head-body length, tail length, existing variants (wild, domesticated, laboratory), single/group housing, dry food consumption/24 h, water intake/24 h, basal metabolic rate mlO2/g/h, environmental temperature, sand baths, urine output ml/24 h, fecal output g/24 h, size of fecal droplet, hair length, life span, length of oestrus cycle, duration of pregnancy, building nest, litter size, stage of musculoskeletal maturity at birth, and the duration of weaning. Characteristics were obtained by searching SCOPUS as well as the World Wide Web with key words for each of the species in English, Latin and, local language name. These characteristics were compared in order to find most appropriate species. Twelve precocial rodent species were identified. There is not enough data for Common yellow-toothed cavy, and Eastern spiny mouse. Inappropriate species were: Gundis, Dassie rat are a more demanding species for appropriate tending, litter size is small; Octodon degus requires sand baths as well as a nest during the first two weeks after delivery; muscle maturity of Spiny mouse at birth (myotubular stage), does not correspond to the human (late histochemical stage); Chinchilla requires separately housing, daily sand baths, has upper limit of weight. Possibility of keeping Southern mountain cavy as pet animal, short estrus, large litter size, absence of the need for nest and sand baths, makes this species the most promising candidates for experiments on ISS. If an experiment is planned with exposing gravid animals before term of the birth, then they might be kept together in the existing Rodent Habitat (USA). If an experiment with birth in microgravity is planned on ISS, the existing habitats do not provide conditions for such an experiment. It is necessary to develop habitats for separate keeping of pregnant animals to enable the following: 1. undisturbed delivery 2. prevent the possibility of hurting the newborns 3. ensure adequate post-partum maternal care and nursing.
T2  - Life Sciences in Space Research
T1  - Which precocial rodent species is more suitable as the experimental model of microgravity influence on prenatal musculosketal development on international space station?
VL  - 33
DO  - 10.1016/j.lssr.2022.04.001
SP  - 48
EP  - 57
ER  - 

@article{
author = "Sekulić, Slobodan and Jovanović, Aleksandar and Živanović, Željko and Simić, Svetlana and Kesić, Srđan and Petković, Branka and Čapo, Ivan and van Loon, Jack J",
year = "2022",
abstract = "The International Space Station (ISS) has the possibility to perform experiments regarding rodent reproduction in microgravity. The musculoskeletal system at birth in precocial rodent species more resembles the human than that of altricial rodent species. For precocial rodent species with body weight ≤ 500 g (limit of ISS) determined were: adult body mass, newborn body mass, head-body length, tail length, existing variants (wild, domesticated, laboratory), single/group housing, dry food consumption/24 h, water intake/24 h, basal metabolic rate mlO2/g/h, environmental temperature, sand baths, urine output ml/24 h, fecal output g/24 h, size of fecal droplet, hair length, life span, length of oestrus cycle, duration of pregnancy, building nest, litter size, stage of musculoskeletal maturity at birth, and the duration of weaning. Characteristics were obtained by searching SCOPUS as well as the World Wide Web with key words for each of the species in English, Latin and, local language name. These characteristics were compared in order to find most appropriate species. Twelve precocial rodent species were identified. There is not enough data for Common yellow-toothed cavy, and Eastern spiny mouse. Inappropriate species were: Gundis, Dassie rat are a more demanding species for appropriate tending, litter size is small; Octodon degus requires sand baths as well as a nest during the first two weeks after delivery; muscle maturity of Spiny mouse at birth (myotubular stage), does not correspond to the human (late histochemical stage); Chinchilla requires separately housing, daily sand baths, has upper limit of weight. Possibility of keeping Southern mountain cavy as pet animal, short estrus, large litter size, absence of the need for nest and sand baths, makes this species the most promising candidates for experiments on ISS. If an experiment is planned with exposing gravid animals before term of the birth, then they might be kept together in the existing Rodent Habitat (USA). If an experiment with birth in microgravity is planned on ISS, the existing habitats do not provide conditions for such an experiment. It is necessary to develop habitats for separate keeping of pregnant animals to enable the following: 1. undisturbed delivery 2. prevent the possibility of hurting the newborns 3. ensure adequate post-partum maternal care and nursing.",
journal = "Life Sciences in Space Research",
title = "Which precocial rodent species is more suitable as the experimental model of microgravity influence on prenatal musculosketal development on international space station?",
volume = "33",
doi = "10.1016/j.lssr.2022.04.001",
pages = "48-57"
}

Sekulić, S., Jovanović, A., Živanović, Ž., Simić, S., Kesić, S., Petković, B., Čapo, I.,& van Loon, J. J.. (2022). Which precocial rodent species is more suitable as the experimental model of microgravity influence on prenatal musculosketal development on international space station?. in Life Sciences in Space Research, 33, 48-57.
https://doi.org/10.1016/j.lssr.2022.04.001

Sekulić S, Jovanović A, Živanović Ž, Simić S, Kesić S, Petković B, Čapo I, van Loon JJ. Which precocial rodent species is more suitable as the experimental model of microgravity influence on prenatal musculosketal development on international space station?. in Life Sciences in Space Research. 2022;33:48-57.
doi:10.1016/j.lssr.2022.04.001 .

Sekulić, Slobodan, Jovanović, Aleksandar, Živanović, Željko, Simić, Svetlana, Kesić, Srđan, Petković, Branka, Čapo, Ivan, van Loon, Jack J, "Which precocial rodent species is more suitable as the experimental model of microgravity influence on prenatal musculosketal development on international space station?" in Life Sciences in Space Research, 33 (2022):48-57,
https://doi.org/10.1016/j.lssr.2022.04.001 . .

TY  - JOUR
AU  - Sekulić, Slobodan
AU  - Jakovljević, Branislava
AU  - Korovljev, Darinka
AU  - Simić, Svetlana
AU  - Čapo, Ivan
AU  - Podgorac, Jelena
AU  - Martać, Ljiljana
AU  - Kesić, Srđan
AU  - Rakić, Srđan
AU  - Petković, Branka
PY  - 2022
UR  - https://www.frontiersin.org/articles/10.3389/fphys.2021.810391/full
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4787
AB  - Polyhydramnios is a condition related to an excessive accumulation of amniotic fluid
in the third trimester of pregnancy and it can be acute and chronic depending on
the duration. Published data suggest that during muscle development, in the stage
of late histochemical differentiation decreased mechanical loading cause decreased
expression of myosin heavy chain (MHC) type 1 leading to slow-to-fast transition. In the
case of chronic polyhydramnios, histochemical muscle differentiation could be affected
as a consequence of permanent decreased physical loading. Most affected would
be muscles which are the most active i.e., spine extensor muscles and muscles of
legs. Long-lasting decreased mechanical loading on muscle should cause decreased
expression of MHC type 1 leading to slow-to-fast transition, decreased number of
muscle fiber type I especially in extensor muscles of spine and legs. Additionally,
because MHC type 1 is present in all skeletal muscles it could lead to various degrees
of hypotrophy depending on constituting a percentage of MHC type 1 in affected
muscles. These changes in the case of preexisting muscle disorders have the potential
to deteriorate the muscle condition additionally. Given these facts, idiopathic chronic
polyhydramnios is a rare opportunity to study the influence of reduced physical loading
on muscle development in the human fetus. Also, it could be a medical entity to examine
the influence of micro- and hypogravity conditions on the development of the fetal
muscular system during the last trimester of gestation.
PB  - Switzerland: Frontiers Media SA
T2  - Frontiers in Physiology
T1  - Chronic Polyhydramnios: A Medical Entity Which Could Be a Model of Muscle Development in Decreased Mechanical Loading Condition
VL  - 12
DO  - 10.3389/fphys.2021.810391
SP  - 810391
ER  - 

@article{
author = "Sekulić, Slobodan and Jakovljević, Branislava and Korovljev, Darinka and Simić, Svetlana and Čapo, Ivan and Podgorac, Jelena and Martać, Ljiljana and Kesić, Srđan and Rakić, Srđan and Petković, Branka",
year = "2022",
abstract = "Polyhydramnios is a condition related to an excessive accumulation of amniotic fluid
in the third trimester of pregnancy and it can be acute and chronic depending on
the duration. Published data suggest that during muscle development, in the stage
of late histochemical differentiation decreased mechanical loading cause decreased
expression of myosin heavy chain (MHC) type 1 leading to slow-to-fast transition. In the
case of chronic polyhydramnios, histochemical muscle differentiation could be affected
as a consequence of permanent decreased physical loading. Most affected would
be muscles which are the most active i.e., spine extensor muscles and muscles of
legs. Long-lasting decreased mechanical loading on muscle should cause decreased
expression of MHC type 1 leading to slow-to-fast transition, decreased number of
muscle fiber type I especially in extensor muscles of spine and legs. Additionally,
because MHC type 1 is present in all skeletal muscles it could lead to various degrees
of hypotrophy depending on constituting a percentage of MHC type 1 in affected
muscles. These changes in the case of preexisting muscle disorders have the potential
to deteriorate the muscle condition additionally. Given these facts, idiopathic chronic
polyhydramnios is a rare opportunity to study the influence of reduced physical loading
on muscle development in the human fetus. Also, it could be a medical entity to examine
the influence of micro- and hypogravity conditions on the development of the fetal
muscular system during the last trimester of gestation.",
publisher = "Switzerland: Frontiers Media SA",
journal = "Frontiers in Physiology",
title = "Chronic Polyhydramnios: A Medical Entity Which Could Be a Model of Muscle Development in Decreased Mechanical Loading Condition",
volume = "12",
doi = "10.3389/fphys.2021.810391",
pages = "810391"
}

Sekulić, S., Jakovljević, B., Korovljev, D., Simić, S., Čapo, I., Podgorac, J., Martać, L., Kesić, S., Rakić, S.,& Petković, B.. (2022). Chronic Polyhydramnios: A Medical Entity Which Could Be a Model of Muscle Development in Decreased Mechanical Loading Condition. in Frontiers in Physiology
Switzerland: Frontiers Media SA., 12, 810391.
https://doi.org/10.3389/fphys.2021.810391

Sekulić S, Jakovljević B, Korovljev D, Simić S, Čapo I, Podgorac J, Martać L, Kesić S, Rakić S, Petković B. Chronic Polyhydramnios: A Medical Entity Which Could Be a Model of Muscle Development in Decreased Mechanical Loading Condition. in Frontiers in Physiology. 2022;12:810391.
doi:10.3389/fphys.2021.810391 .

Sekulić, Slobodan, Jakovljević, Branislava, Korovljev, Darinka, Simić, Svetlana, Čapo, Ivan, Podgorac, Jelena, Martać, Ljiljana, Kesić, Srđan, Rakić, Srđan, Petković, Branka, "Chronic Polyhydramnios: A Medical Entity Which Could Be a Model of Muscle Development in Decreased Mechanical Loading Condition" in Frontiers in Physiology, 12 (2022):810391,
https://doi.org/10.3389/fphys.2021.810391 . .

TY  - CONF
AU  - Milićević, Katarina
AU  - Lazarević, Milica
AU  - Momčilović, Miljana
AU  - Todorović, Nataša
AU  - Petković, Branka
AU  - Stojadinović, Gordana
AU  - Nikolić, Ljiljana
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5504
AB  - Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system (CNS)
characterized by infiltration of lymphocytes that leads to myelin damage and neurodegeneration.
The complex interaction between CNS-infiltrating immune cells (CNS-IIC) and astrocytes is an
important contributor to the disease progression. Here, we investigate how naïve astrocytes respond
to autoreactive immune cells present in the CNS at different stages of the disease. For this purpose,
CNS-IICs were isolated from the spinal cords of rats with experimental autoimmune
encephalomyelitis at onset, late-onset and the peak of the disease. Naïve astrocytes, isolated from
the spinal cords of wild-type rat pups, responded to brief bath application of CNS-IIC by robust
elevation of intracellular Ca2+ independently of the disease stage. Our data suggest that direct
contact between astrocytes and CNS-IICs induces Ca2+ changes in astrocytes and points to the new
aspect of cell-cell interactions in the propagation of neuroinflammatory response in CNS
autoimmunity.
PB  - Belgrade: Society of Physical Chemists of Serbia
C3  - Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia
T1  - Naïve astrocytes react to CNS-infiltrated immune cells
SP  - 267
EP  - 270
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5504
ER  - 

@conference{
editor = "Čupić, Željko, Anić, Slobodan",
author = "Milićević, Katarina and Lazarević, Milica and Momčilović, Miljana and Todorović, Nataša and Petković, Branka and Stojadinović, Gordana and Nikolić, Ljiljana",
year = "2022",
abstract = "Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system (CNS)
characterized by infiltration of lymphocytes that leads to myelin damage and neurodegeneration.
The complex interaction between CNS-infiltrating immune cells (CNS-IIC) and astrocytes is an
important contributor to the disease progression. Here, we investigate how naïve astrocytes respond
to autoreactive immune cells present in the CNS at different stages of the disease. For this purpose,
CNS-IICs were isolated from the spinal cords of rats with experimental autoimmune
encephalomyelitis at onset, late-onset and the peak of the disease. Naïve astrocytes, isolated from
the spinal cords of wild-type rat pups, responded to brief bath application of CNS-IIC by robust
elevation of intracellular Ca2+ independently of the disease stage. Our data suggest that direct
contact between astrocytes and CNS-IICs induces Ca2+ changes in astrocytes and points to the new
aspect of cell-cell interactions in the propagation of neuroinflammatory response in CNS
autoimmunity.",
publisher = "Belgrade: Society of Physical Chemists of Serbia",
journal = "Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia",
title = "Naïve astrocytes react to CNS-infiltrated immune cells",
pages = "267-270",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5504"
}

Čupić, Ž., Anić, S., Milićević, K., Lazarević, M., Momčilović, M., Todorović, N., Petković, B., Stojadinović, G.,& Nikolić, L.. (2022). Naïve astrocytes react to CNS-infiltrated immune cells. in Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia
Belgrade: Society of Physical Chemists of Serbia., 267-270.
https://hdl.handle.net/21.15107/rcub_ibiss_5504

Čupić Ž, Anić S, Milićević K, Lazarević M, Momčilović M, Todorović N, Petković B, Stojadinović G, Nikolić L. Naïve astrocytes react to CNS-infiltrated immune cells. in Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia. 2022;:267-270.
https://hdl.handle.net/21.15107/rcub_ibiss_5504 .

Čupić, Željko, Anić, Slobodan, Milićević, Katarina, Lazarević, Milica, Momčilović, Miljana, Todorović, Nataša, Petković, Branka, Stojadinović, Gordana, Nikolić, Ljiljana, "Naïve astrocytes react to CNS-infiltrated immune cells" in Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia (2022):267-270,
https://hdl.handle.net/21.15107/rcub_ibiss_5504 .

TY  - CONF
AU  - Nikolić, Ljiljana
AU  - Vidović, Marija
AU  - Todorović, Nataša
AU  - Petković, Branka
AU  - Stojadinović, Gordana
AU  - Martać, Ljiljana
AU  - Bogdanović Pristov, Jelena
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5508
AB  - Investigating membrane properties of plants is a challenging task, considering that success of
experiments is highly dependent on the possibility to isolate metabolically active protoplasts that
can withstand membrane current recordings. The aim of the present work is to obtain viable
protoplasts derived from root cells of Pisum sativum that can be used for the whole-cell patchclamp. We designed the procedure of the pea protoplasts isolation that delivers stable protoplasts
with preserved membrane integrity suitable for electrophysiological experiments. We applied a
custom approach for patch-clamping protoplasts using a microscope with a movable microscope
stage. We recorded prominent inward and prominent outward types of membrane current profiles of
protoplasts. Obtained data indicate that optimized isolation protocol and custom system for patchclamping, can be applied to study membrane properties of root protoplasts.
PB  - Belgrade: Society of Physical Chemists of Serbia
C3  - Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia
T1  - Protoplast patch-clamping using an upright microscope with a movable stage
SP  - 271
EP  - 274
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5508
ER  - 

@conference{
editor = "Čupić, Željko, Anić, Slobodan",
author = "Nikolić, Ljiljana and Vidović, Marija and Todorović, Nataša and Petković, Branka and Stojadinović, Gordana and Martać, Ljiljana and Bogdanović Pristov, Jelena",
year = "2022",
abstract = "Investigating membrane properties of plants is a challenging task, considering that success of
experiments is highly dependent on the possibility to isolate metabolically active protoplasts that
can withstand membrane current recordings. The aim of the present work is to obtain viable
protoplasts derived from root cells of Pisum sativum that can be used for the whole-cell patchclamp. We designed the procedure of the pea protoplasts isolation that delivers stable protoplasts
with preserved membrane integrity suitable for electrophysiological experiments. We applied a
custom approach for patch-clamping protoplasts using a microscope with a movable microscope
stage. We recorded prominent inward and prominent outward types of membrane current profiles of
protoplasts. Obtained data indicate that optimized isolation protocol and custom system for patchclamping, can be applied to study membrane properties of root protoplasts.",
publisher = "Belgrade: Society of Physical Chemists of Serbia",
journal = "Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia",
title = "Protoplast patch-clamping using an upright microscope with a movable stage",
pages = "271-274",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5508"
}

Čupić, Ž., Anić, S., Nikolić, L., Vidović, M., Todorović, N., Petković, B., Stojadinović, G., Martać, L.,& Bogdanović Pristov, J.. (2022). Protoplast patch-clamping using an upright microscope with a movable stage. in Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia
Belgrade: Society of Physical Chemists of Serbia., 271-274.
https://hdl.handle.net/21.15107/rcub_ibiss_5508

Čupić Ž, Anić S, Nikolić L, Vidović M, Todorović N, Petković B, Stojadinović G, Martać L, Bogdanović Pristov J. Protoplast patch-clamping using an upright microscope with a movable stage. in Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia. 2022;:271-274.
https://hdl.handle.net/21.15107/rcub_ibiss_5508 .

Čupić, Željko, Anić, Slobodan, Nikolić, Ljiljana, Vidović, Marija, Todorović, Nataša, Petković, Branka, Stojadinović, Gordana, Martać, Ljiljana, Bogdanović Pristov, Jelena, "Protoplast patch-clamping using an upright microscope with a movable stage" in Proceedings: Physical Chemistry 2022, Vol. 1.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia (2022):271-274,
https://hdl.handle.net/21.15107/rcub_ibiss_5508 .

TY  - CONF
AU  - Podgorac, Jelena
AU  - Petković, Branka
AU  - Martać, Ljiljana
AU  - Stojadinović, Gordana
AU  - Pešić, Vesna
AU  - Sekulić, Slobodan
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5745
AB  - Valproinska kiselina (VPK) je lek izbora u terapiji epilepsija kod trudnica, iako može uzrokovati različite poremećaje kod potomstva.1 Naša prethodna istraživanja su pokazala usporen somatski razvoj i odloženo sazrevanje motoričkog sistema u ranom postnatalnom periodu kod potomaka miševa koji su prenatalno kontinuirano izlagani VPK.2 Sa ciljem da proširimo saznanja vezana za model i procenimo dugotrajnost posledica VPK, u ovoj studiji ispitivali smo karakteristike psihomotornog ponašanja adolescentnih i odraslih mužjaka miševa u odgovoru na novu sredinu. Ženke su kontinuirano injecirane rastvorom VPK (50, 100 ili 400 mg/kg/dan; subkutano) tokom celog perioda gestacije. Potomstvo muškog pola starosti 6 nedelja (adolescenti) i 12 nedelja (odrasli) je ispitivano u testu otvorenog polja (open field test) u cilju procene lokomotorne, stereotipne i vertikalne aktivnosti. Rezultati ukazuju da tretman VPK: (1) nema uticaja na lokomotornu i vertikalnu aktivnost adolescentnih i odraslih jedinki, (2) smanjuje stereotipnu aktivnost adolescentnih jedinki u dozi od 100 i 400 mg/kg/dan. Dobijeni rezultati ukazuju da prenatalno kontinuirano izlaganje VPK ima dugotrajne posledice kod potomstva muškog pola, narušavajući očekivani odgovor adolescentnih jedinki na novu sredinu. Izostanak efekta kod odraslih jedinki se može objasniti spontanim dovođenjem sistema u ravnotežu usled maturacionih promena, što ipak ostaje da se dodatno proceni u drugim testovima zasnovanim na spontanom odgovoru na novu sredinu.
AB  - Валпроинска киселина (ВПК) је лек избора у терапији епилепсија код трудница,
иако може узроковати различите поремећаје код потомства.1 Наша претходна
истраживања су показала успорен соматски развој и одложено сазревање
моторичког система у раном постнаталном периоду код потомака мишева који су
пренатално континуирано излагани ВПК.2 Са циљем да проширимо сазнања везана
за модел и проценимо дуготрајност последица ВПК, у овој студији испитивали смо
карактеристике психомоторног понашања адолесцентних и одраслих мужјака
мишева у одговору на нову средину. Женке су континуирано ињециране раствором
ВПК (50, 100 или 400 мг/кг/дан; субкутано) током целог периода гестације.
Потомство мушког пола старости 6 недеља (адолесценти) и 12 недеља (одрасли) је
испитивано у тесту отвореног поља (open field test) у циљу процене локомоторне,
стереотипне и вертикалне активности. Резултати указују да третман ВПК: (1) нема
утицаја на локомоторну и вертикалну активност адолесцентних и одраслих
јединки, (2) смањује стереотипну активност адолесцентних јединки у дози од 100 и
400 мг/кг/дан. Добијени резултати указују да пренатално континуирано излагање
ВПК има дуготрајне последице код потомства мушког пола, нарушавајући
очекивани одговор адолесцентних јединки на нову средину. Изостанак ефекта код
одраслих јединки се може објаснити спонтаним довођењем система у равнотежу
услед матурационих промена, што ипак остаје да се додатно процени у другим
тестовима заснованим на спонтаном одговору на нову средину.
PB  - Belgrade: Serbian Biological Society
C3  - Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia
T1  - Uticaj kontinuiranog izlaganja valproinskoj kiselini tokom prenatalnog razvoja na psihomotorno ponašanje adolescentnih i odraslih mužjaka miševa
T1  - Утицај континуираног излагања валпроинској киселини током пренаталног развоја на психомоторно понашање адолесцентних и одраслих мужјака мишева
SP  - 369
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5745
ER  - 

@conference{
author = "Podgorac, Jelena and Petković, Branka and Martać, Ljiljana and Stojadinović, Gordana and Pešić, Vesna and Sekulić, Slobodan",
year = "2022",
abstract = "Valproinska kiselina (VPK) je lek izbora u terapiji epilepsija kod trudnica, iako može uzrokovati različite poremećaje kod potomstva.1 Naša prethodna istraživanja su pokazala usporen somatski razvoj i odloženo sazrevanje motoričkog sistema u ranom postnatalnom periodu kod potomaka miševa koji su prenatalno kontinuirano izlagani VPK.2 Sa ciljem da proširimo saznanja vezana za model i procenimo dugotrajnost posledica VPK, u ovoj studiji ispitivali smo karakteristike psihomotornog ponašanja adolescentnih i odraslih mužjaka miševa u odgovoru na novu sredinu. Ženke su kontinuirano injecirane rastvorom VPK (50, 100 ili 400 mg/kg/dan; subkutano) tokom celog perioda gestacije. Potomstvo muškog pola starosti 6 nedelja (adolescenti) i 12 nedelja (odrasli) je ispitivano u testu otvorenog polja (open field test) u cilju procene lokomotorne, stereotipne i vertikalne aktivnosti. Rezultati ukazuju da tretman VPK: (1) nema uticaja na lokomotornu i vertikalnu aktivnost adolescentnih i odraslih jedinki, (2) smanjuje stereotipnu aktivnost adolescentnih jedinki u dozi od 100 i 400 mg/kg/dan. Dobijeni rezultati ukazuju da prenatalno kontinuirano izlaganje VPK ima dugotrajne posledice kod potomstva muškog pola, narušavajući očekivani odgovor adolescentnih jedinki na novu sredinu. Izostanak efekta kod odraslih jedinki se može objasniti spontanim dovođenjem sistema u ravnotežu usled maturacionih promena, što ipak ostaje da se dodatno proceni u drugim testovima zasnovanim na spontanom odgovoru na novu sredinu., Валпроинска киселина (ВПК) је лек избора у терапији епилепсија код трудница,
иако може узроковати различите поремећаје код потомства.1 Наша претходна
истраживања су показала успорен соматски развој и одложено сазревање
моторичког система у раном постнаталном периоду код потомака мишева који су
пренатално континуирано излагани ВПК.2 Са циљем да проширимо сазнања везана
за модел и проценимо дуготрајност последица ВПК, у овој студији испитивали смо
карактеристике психомоторног понашања адолесцентних и одраслих мужјака
мишева у одговору на нову средину. Женке су континуирано ињециране раствором
ВПК (50, 100 или 400 мг/кг/дан; субкутано) током целог периода гестације.
Потомство мушког пола старости 6 недеља (адолесценти) и 12 недеља (одрасли) је
испитивано у тесту отвореног поља (open field test) у циљу процене локомоторне,
стереотипне и вертикалне активности. Резултати указују да третман ВПК: (1) нема
утицаја на локомоторну и вертикалну активност адолесцентних и одраслих
јединки, (2) смањује стереотипну активност адолесцентних јединки у дози од 100 и
400 мг/кг/дан. Добијени резултати указују да пренатално континуирано излагање
ВПК има дуготрајне последице код потомства мушког пола, нарушавајући
очекивани одговор адолесцентних јединки на нову средину. Изостанак ефекта код
одраслих јединки се може објаснити спонтаним довођењем система у равнотежу
услед матурационих промена, што ипак остаје да се додатно процени у другим
тестовима заснованим на спонтаном одговору на нову средину.",
publisher = "Belgrade: Serbian Biological Society",
journal = "Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia",
title = "Uticaj kontinuiranog izlaganja valproinskoj kiselini tokom prenatalnog razvoja na psihomotorno ponašanje adolescentnih i odraslih mužjaka miševa, Утицај континуираног излагања валпроинској киселини током пренаталног развоја на психомоторно понашање адолесцентних и одраслих мужјака мишева",
pages = "369",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5745"
}

Podgorac, J., Petković, B., Martać, L., Stojadinović, G., Pešić, V.,& Sekulić, S.. (2022). Uticaj kontinuiranog izlaganja valproinskoj kiselini tokom prenatalnog razvoja na psihomotorno ponašanje adolescentnih i odraslih mužjaka miševa. in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia
Belgrade: Serbian Biological Society., 369.
https://hdl.handle.net/21.15107/rcub_ibiss_5745

Podgorac J, Petković B, Martać L, Stojadinović G, Pešić V, Sekulić S. Uticaj kontinuiranog izlaganja valproinskoj kiselini tokom prenatalnog razvoja na psihomotorno ponašanje adolescentnih i odraslih mužjaka miševa. in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia. 2022;:369.
https://hdl.handle.net/21.15107/rcub_ibiss_5745 .

Podgorac, Jelena, Petković, Branka, Martać, Ljiljana, Stojadinović, Gordana, Pešić, Vesna, Sekulić, Slobodan, "Uticaj kontinuiranog izlaganja valproinskoj kiselini tokom prenatalnog razvoja na psihomotorno ponašanje adolescentnih i odraslih mužjaka miševa" in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia (2022):369,
https://hdl.handle.net/21.15107/rcub_ibiss_5745 .

TY  - CONF
AU  - Kesić, Srđan
AU  - Stojadinović, Gordana
AU  - Martać, Ljiljana
AU  - Sekulić, Slobodan
AU  - Petković, Branka
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5746
AB  - Akutna primena dizocilpina (MK-801), antagoniste glutaminskih N-metil-D-aspartatnih (NMDA) receptora, prouzrokuje psihotične simptome slične šizofreniji kod pacova.1 Ekstremno niskofrekventno magnetno polje (ENF-MP), kao fizički faktor životne sredine, može stimulisati aktivnost NMDA receptora,2 mada ovaj efekat ENF-MP u uslovima disregulisane glutaminske transmisije nije poznat. Stoga, ova studija se bavi uticajem kontinuiranog izlaganja ENF-MP (50 Hz, 0,5 mT) u toku 7 dana na psihomotorno ponašanje pacova izazvano akutnom primenom MK-801 (0,1 mg/kg, i.p.). U toku eksperimenta odrasli mužjaci Wistar pacova postavljeni su u blizini uključenog/isključenog ENF-MP generatora, neposredno nakon prestanka izlaganja injecirani MK-801/fiziološkim rastvorom i podvrgnuti testu otvorenog polja (open field test) u toku 2 sata. ANY-maze softverom je urađena analiza lokomotorne i stereotipne aktivnosti. Pokazano je da: (1) 7-dnevno kontinuirano izlaganje ENF-MP nema uticaja, dok akutna primena MK-801 značajno povećava lokomotornu i stereotipnu aktivnost pacova od 60. do 90. min registracije ponašanja; (2) 7- dnevno kontinuirano izlaganje ENF-MP značajno intenzivira efekte izazvane akutnom primenom MK-801 od 60. do 120. min registracije ponašanja. Dobijeni rezultati ukazuju na modulatorni uticaj kontinuiranog izlaganja ENF-MP pomenutih karakteristika na glutaminsku transmisiju, koji dolazi do izražaja u uslovima njene farmakološke manipulacije.
AB  - Акутна примена дизоцилпина (MK-801), антагонисте глутаминских Н-метил-Д-
аспартатних (NMDA) рецептора, проузрокује психотичне симптоме сличне
шизофренији код пацова.1 Екстремно нискофреквентно магнетно поље (ЕНФ-МП),
као физички фактор животне средине, може стимулисати активност NMDA
рецептора,2 мада овај ефекат ЕНФ-МП у условима дисрегулисане глутаминске
трансмисије није познат. Стога, ова студија се бави утицајем континуираног
излагања ЕНФ-МП (50 Hz, 0,5 mT) у току 7 дана на психомоторно понашање
пацова изазвано акутном применом MK-801 (0,1 mg/kg, и.п.). У току експеримента
одрасли мужјаци Wistar пацова постављени су у близини укљученог/искљученог
ЕНФ-МП генератора, непосредно након престанка излагања инјецирани MK-
801/физиолошким раствором и подвргнути тесту отвореног поља (open field test) у
току 2 сата. ANY-maze софтвером je урађена анализa локомоторне и стереотипне
активности. Показано је да: (1) 7-дневно континуирано излагање ЕНФ-МП нема
утицаја, док акутна примена МK-801 значајно повећава локомоторну и
стереотипну активност пацова од 60. до 90. мин регистрације понашања; (2) 7-
дневно континуирано излагање ЕНФ-МП значајно интензивира ефекте изазване
акутном применом МK-801 од 60. до 120. мин регистрације понашања. Добијени
резултати указују на модулаторни утицај континуираног излагања ЕНФ-МП
поменутих карактеристика на глутаминску трансмисију, који долази до изражаја у
условима њене фармаколошке манипулације.
PB  - Belgrade: Serbian Biological Society
C3  - Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia
T1  - Uticaj magnetnog polja (50 Hz, 0,5 mT) na psihomotorno ponašanje pacova izazvano akutnom primenom dizocilpina
T1  - Утицај магнетног поља (50 Hz, 0,5 mT) на психомоторно понашање пацова изазвано акутном применом дизоцилпина
SP  - 388
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5746
ER  - 

@conference{
author = "Kesić, Srđan and Stojadinović, Gordana and Martać, Ljiljana and Sekulić, Slobodan and Petković, Branka",
year = "2022",
abstract = "Akutna primena dizocilpina (MK-801), antagoniste glutaminskih N-metil-D-aspartatnih (NMDA) receptora, prouzrokuje psihotične simptome slične šizofreniji kod pacova.1 Ekstremno niskofrekventno magnetno polje (ENF-MP), kao fizički faktor životne sredine, može stimulisati aktivnost NMDA receptora,2 mada ovaj efekat ENF-MP u uslovima disregulisane glutaminske transmisije nije poznat. Stoga, ova studija se bavi uticajem kontinuiranog izlaganja ENF-MP (50 Hz, 0,5 mT) u toku 7 dana na psihomotorno ponašanje pacova izazvano akutnom primenom MK-801 (0,1 mg/kg, i.p.). U toku eksperimenta odrasli mužjaci Wistar pacova postavljeni su u blizini uključenog/isključenog ENF-MP generatora, neposredno nakon prestanka izlaganja injecirani MK-801/fiziološkim rastvorom i podvrgnuti testu otvorenog polja (open field test) u toku 2 sata. ANY-maze softverom je urađena analiza lokomotorne i stereotipne aktivnosti. Pokazano je da: (1) 7-dnevno kontinuirano izlaganje ENF-MP nema uticaja, dok akutna primena MK-801 značajno povećava lokomotornu i stereotipnu aktivnost pacova od 60. do 90. min registracije ponašanja; (2) 7- dnevno kontinuirano izlaganje ENF-MP značajno intenzivira efekte izazvane akutnom primenom MK-801 od 60. do 120. min registracije ponašanja. Dobijeni rezultati ukazuju na modulatorni uticaj kontinuiranog izlaganja ENF-MP pomenutih karakteristika na glutaminsku transmisiju, koji dolazi do izražaja u uslovima njene farmakološke manipulacije., Акутна примена дизоцилпина (MK-801), антагонисте глутаминских Н-метил-Д-
аспартатних (NMDA) рецептора, проузрокује психотичне симптоме сличне
шизофренији код пацова.1 Екстремно нискофреквентно магнетно поље (ЕНФ-МП),
као физички фактор животне средине, може стимулисати активност NMDA
рецептора,2 мада овај ефекат ЕНФ-МП у условима дисрегулисане глутаминске
трансмисије није познат. Стога, ова студија се бави утицајем континуираног
излагања ЕНФ-МП (50 Hz, 0,5 mT) у току 7 дана на психомоторно понашање
пацова изазвано акутном применом MK-801 (0,1 mg/kg, и.п.). У току експеримента
одрасли мужјаци Wistar пацова постављени су у близини укљученог/искљученог
ЕНФ-МП генератора, непосредно након престанка излагања инјецирани MK-
801/физиолошким раствором и подвргнути тесту отвореног поља (open field test) у
току 2 сата. ANY-maze софтвером je урађена анализa локомоторне и стереотипне
активности. Показано је да: (1) 7-дневно континуирано излагање ЕНФ-МП нема
утицаја, док акутна примена МK-801 значајно повећава локомоторну и
стереотипну активност пацова од 60. до 90. мин регистрације понашања; (2) 7-
дневно континуирано излагање ЕНФ-МП значајно интензивира ефекте изазване
акутном применом МK-801 од 60. до 120. мин регистрације понашања. Добијени
резултати указују на модулаторни утицај континуираног излагања ЕНФ-МП
поменутих карактеристика на глутаминску трансмисију, који долази до изражаја у
условима њене фармаколошке манипулације.",
publisher = "Belgrade: Serbian Biological Society",
journal = "Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia",
title = "Uticaj magnetnog polja (50 Hz, 0,5 mT) na psihomotorno ponašanje pacova izazvano akutnom primenom dizocilpina, Утицај магнетног поља (50 Hz, 0,5 mT) на психомоторно понашање пацова изазвано акутном применом дизоцилпина",
pages = "388",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5746"
}

Kesić, S., Stojadinović, G., Martać, L., Sekulić, S.,& Petković, B.. (2022). Uticaj magnetnog polja (50 Hz, 0,5 mT) na psihomotorno ponašanje pacova izazvano akutnom primenom dizocilpina. in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia
Belgrade: Serbian Biological Society., 388.
https://hdl.handle.net/21.15107/rcub_ibiss_5746

Kesić S, Stojadinović G, Martać L, Sekulić S, Petković B. Uticaj magnetnog polja (50 Hz, 0,5 mT) na psihomotorno ponašanje pacova izazvano akutnom primenom dizocilpina. in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia. 2022;:388.
https://hdl.handle.net/21.15107/rcub_ibiss_5746 .

Kesić, Srđan, Stojadinović, Gordana, Martać, Ljiljana, Sekulić, Slobodan, Petković, Branka, "Uticaj magnetnog polja (50 Hz, 0,5 mT) na psihomotorno ponašanje pacova izazvano akutnom primenom dizocilpina" in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia (2022):388,
https://hdl.handle.net/21.15107/rcub_ibiss_5746 .

TY  - CONF
AU  - Podgorac, Jelena
AU  - Petković, Branka
AU  - Stojadinović, Gordana
AU  - Martać, Ljiljana
AU  - Sekulić, Slobodan
AU  - Pešić, Vesna
PY  - 2022
UR  - https://kenesvm.azureedge.net/public/general/FENS2022.pdf
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5734
AB  - Aims: Levetiracetam (LEV), which belongs to a new generation of antiepileptic drugs, has been recognized as a relatively safe antiepileptic therapy, according to studies on neurodevelopmental outcomes in children exposed to LEV in utero, although some animal studies reported skeletal abnormalities. This study deals with the influence of prenatal exposure to LEV in the doses that cover therapeutic range in humans on gross skeletal structure and anxiety-like behavior in adolescent mice. Methods: Adult 8-weeks old female NMRI mice were randomly divided into four groups and treated subcutaneously during breeding and gestation with saline (control) or LEV in the doses of 158 mg/kg/day (LEV-158), 211 mg/kg/day (LEV-211), or 316 mg/kg/day (LEV-316). After delivery, each female with the progeny was housed separately. Weaning and separation by sex were done on the 20th postnatal day (P20). The elevated plus-maze test was used to assess the anxiety-like behavior in both male and female offspring on P37. Results: Females and males in the LEV-158 and LEV-316 group displayed less anxiety-like behavior compared to the control, while in the LEV-211 group such behavior was not observed. Sex-related differences in anxiety-like behavior were not detected within any LEV group, as well as visible skeletal malformations. Conclusion: The findings in the mouse model suggest that prenatal exposure to LEV could be associated with less anxiety-like behavior in adolescence, paying attention to the U-shaped dose-response and highlighting the behavioral outcomes of small LEV doses.
PB  - Federation of European Neuroscience Societies
C3  - E-Book of Abstracts: FENS Forum 2022; 2022 Jul 9-13; Paris, France
T1  - Anxiety-like behavior in adolescent mice prenatally exposed to different doses of levetiracetam
SP  - S02-173
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5734
ER  - 

@conference{
author = "Podgorac, Jelena and Petković, Branka and Stojadinović, Gordana and Martać, Ljiljana and Sekulić, Slobodan and Pešić, Vesna",
year = "2022",
abstract = "Aims: Levetiracetam (LEV), which belongs to a new generation of antiepileptic drugs, has been recognized as a relatively safe antiepileptic therapy, according to studies on neurodevelopmental outcomes in children exposed to LEV in utero, although some animal studies reported skeletal abnormalities. This study deals with the influence of prenatal exposure to LEV in the doses that cover therapeutic range in humans on gross skeletal structure and anxiety-like behavior in adolescent mice. Methods: Adult 8-weeks old female NMRI mice were randomly divided into four groups and treated subcutaneously during breeding and gestation with saline (control) or LEV in the doses of 158 mg/kg/day (LEV-158), 211 mg/kg/day (LEV-211), or 316 mg/kg/day (LEV-316). After delivery, each female with the progeny was housed separately. Weaning and separation by sex were done on the 20th postnatal day (P20). The elevated plus-maze test was used to assess the anxiety-like behavior in both male and female offspring on P37. Results: Females and males in the LEV-158 and LEV-316 group displayed less anxiety-like behavior compared to the control, while in the LEV-211 group such behavior was not observed. Sex-related differences in anxiety-like behavior were not detected within any LEV group, as well as visible skeletal malformations. Conclusion: The findings in the mouse model suggest that prenatal exposure to LEV could be associated with less anxiety-like behavior in adolescence, paying attention to the U-shaped dose-response and highlighting the behavioral outcomes of small LEV doses.",
publisher = "Federation of European Neuroscience Societies",
journal = "E-Book of Abstracts: FENS Forum 2022; 2022 Jul 9-13; Paris, France",
title = "Anxiety-like behavior in adolescent mice prenatally exposed to different doses of levetiracetam",
pages = "S02-173",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5734"
}

Podgorac, J., Petković, B., Stojadinović, G., Martać, L., Sekulić, S.,& Pešić, V.. (2022). Anxiety-like behavior in adolescent mice prenatally exposed to different doses of levetiracetam. in E-Book of Abstracts: FENS Forum 2022; 2022 Jul 9-13; Paris, France
Federation of European Neuroscience Societies., S02-173.
https://hdl.handle.net/21.15107/rcub_ibiss_5734

Podgorac J, Petković B, Stojadinović G, Martać L, Sekulić S, Pešić V. Anxiety-like behavior in adolescent mice prenatally exposed to different doses of levetiracetam. in E-Book of Abstracts: FENS Forum 2022; 2022 Jul 9-13; Paris, France. 2022;:S02-173.
https://hdl.handle.net/21.15107/rcub_ibiss_5734 .

Podgorac, Jelena, Petković, Branka, Stojadinović, Gordana, Martać, Ljiljana, Sekulić, Slobodan, Pešić, Vesna, "Anxiety-like behavior in adolescent mice prenatally exposed to different doses of levetiracetam" in E-Book of Abstracts: FENS Forum 2022; 2022 Jul 9-13; Paris, France (2022):S02-173,
https://hdl.handle.net/21.15107/rcub_ibiss_5734 .

TY  - CONF
AU  - Janković Tomanić, Milena
AU  - Vranković, Jelena
AU  - Petković, Branka
AU  - Perić Mataruga, Vesna
PY  - 2022
UR  - http://www.eds.org.rs/SES/2022/Zbornik%20rezimea%20XIII%20SES%202022.pdf
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5740
AB  - Tenebrio molitor L. (Coleoptera, Tenebrionidae) (brašneni crv) je holometabolni insekt, koji se smatra jednim od glavnih štetočina silosa i žitarica. Sa druge strane, on se može smatrati i korisnom vrstom, obzirom da je izvor visoko kvalitetnih nutrienata u ishrani životinja, sa perspektivom korišćenja i u ljudskoj ishrani. Takođe je veoma važno istaći da su larve T. molitor osetljive na prisustvo mikotoksina u okruženju. Larve menjaju ponašanje u njihovom prisustvu, događaju se brze biohemijske i fiziološke promene koje ga prate, tako da vrsta T. molitor može imati potencijal za detektovanje mikotoksina u hrani. Za ovu studiju, izabran je mikotoksin zearalenon (ZEA), koji predstavlja sekundarni metabolit gljiva iz roda Fusarium, najčešće F. culmorum i F. graminearum. ZEA je pronañen u uzorcima pšenice i kukuruza širom Evrope u koncentracijama u rasponu od 15 µg/kg do 5700 µg/kg, pa čak i do 14,58 mg/kg (Fruhauf i sar., 2019). Cilj ovog istraživanja je bio da se ispita uticaj mikotoksina dodatog u pšenične mekinje, koje predstavljaju optimalan supstrat za gajenje larvi T. molitor, na aktivnost enzima antioksidativne zaštite, superoksid dismutaze (SOD) i katalaze (CAT), detoksifikacionog enzima glutation-S-transferaze (GST) kao i motornog ponašanje larvi (pređeni put, vreme provedeno u kretanju i prosečna brzina tokom kretanja). Primenjene doze mikotoksina su bile sledeće: 100 µg/kg (što odgovara maksimalno dozvoljenoj vrednosti u kukuruzu namenjenom za neposrednu ishranu ljudi), 2 mg/kg (žitarice i proizvodi od žitarica osim kukuruza namenjeni za ishranu životinja; Preporuka Evropske komisije 2006/576/EC) i 10 mg/kg hrane (što odgovara maksimalnim vrednostima koje se mogu naći u uzorcima žitarica). Koristili smo larve iz populacije gajene u Institutu za biološka istraživanja „Siniša Stanković“, koje su na početku eksperimenta bile prosečne starosti 2 meseca i prosečne težine 106,2 ± 0,8 mg. Uočeno je da prisustvo mikotoksina u hrani značajno utiče na aktivnost enzima SOD (F(3, 50)=11,738, P<0,001) i GST (F(3,50)=7,889, P<0,001), dok ne dovodi do promene u aktivnosti enzima CAT (F(3, 50)=0,775, P=0,513). Aktivnosti enzima SOD i GST su bile značajno više u grupama larvi gajenih na supstratu sa najnižom (100 µg/kg) i najvišom (10 mg/kg) dozom mikotoksina u odnosu na kontrolne larve gajene na supstratu bez mikotoksina. U grupi larvi gajenih na supstratu sa 2 mg/kg mikotoksina, aktivnost ovih enzima je bila na kontrolnom nivou. Mikotoksin prisutan u hrani utiče i na motorno ponašanje jedinki značajno menjajući pređeni put (H(3,33)=8,739, P<0,05) i vreme provedeno u kretanju (H(3,33)=7,866, P<0,05), dok nema uticaja na prosečnu brzinu tokom kretanja (H(3,33)=5,525, P=0,137). Pređeni put i vreme provedeno u kretanju su bili značajno niži u grupama larvi gajenih na supstratu sa najnižom (100 µg/kg) i najvišom (10 mg/kg) dozom mikotoksina, i nepromenjeni u grupi larvi gajenih na supstratu sa 2 mg/kg mikotoksina, u odnosu na kontrolne larve. Naši rezultati ukazuju da prisustvo mikotoksina ZEA u hrani u dozama od 100 µg/kg i 10 mg/kg dovodi do promena u fiziologiji i ponašanju larvi T. molitor, i to povećanja aktivnosti antioksidativnog i detoksifikacionog enzima praćenog smanjenom motornom aktivnošću. Stoga, analiza ovih lako merljivih i osetljivih parametara može biti važna u ispitivanju i ranom otkrivanju kontaminacije hrane ovim veoma opasnim mikotoksinom.
PB  - Belgrade: Entomological Society of Serbia
C3  - Zbornik rezimea: 13. Simpozijum entomologa Srbije sa međunarodnim učešćem; 2022 Sep 14-16; Pirot, Serbia
T1  - Uticaj mikotoksina zearalenona na aktivnost enzima antioksidativne zaštite i ponašanje larvi Tenebrio molitor (L.)
SP  - 38
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5740
ER  - 

@conference{
author = "Janković Tomanić, Milena and Vranković, Jelena and Petković, Branka and Perić Mataruga, Vesna",
year = "2022",
abstract = "Tenebrio molitor L. (Coleoptera, Tenebrionidae) (brašneni crv) je holometabolni insekt, koji se smatra jednim od glavnih štetočina silosa i žitarica. Sa druge strane, on se može smatrati i korisnom vrstom, obzirom da je izvor visoko kvalitetnih nutrienata u ishrani životinja, sa perspektivom korišćenja i u ljudskoj ishrani. Takođe je veoma važno istaći da su larve T. molitor osetljive na prisustvo mikotoksina u okruženju. Larve menjaju ponašanje u njihovom prisustvu, događaju se brze biohemijske i fiziološke promene koje ga prate, tako da vrsta T. molitor može imati potencijal za detektovanje mikotoksina u hrani. Za ovu studiju, izabran je mikotoksin zearalenon (ZEA), koji predstavlja sekundarni metabolit gljiva iz roda Fusarium, najčešće F. culmorum i F. graminearum. ZEA je pronañen u uzorcima pšenice i kukuruza širom Evrope u koncentracijama u rasponu od 15 µg/kg do 5700 µg/kg, pa čak i do 14,58 mg/kg (Fruhauf i sar., 2019). Cilj ovog istraživanja je bio da se ispita uticaj mikotoksina dodatog u pšenične mekinje, koje predstavljaju optimalan supstrat za gajenje larvi T. molitor, na aktivnost enzima antioksidativne zaštite, superoksid dismutaze (SOD) i katalaze (CAT), detoksifikacionog enzima glutation-S-transferaze (GST) kao i motornog ponašanje larvi (pređeni put, vreme provedeno u kretanju i prosečna brzina tokom kretanja). Primenjene doze mikotoksina su bile sledeće: 100 µg/kg (što odgovara maksimalno dozvoljenoj vrednosti u kukuruzu namenjenom za neposrednu ishranu ljudi), 2 mg/kg (žitarice i proizvodi od žitarica osim kukuruza namenjeni za ishranu životinja; Preporuka Evropske komisije 2006/576/EC) i 10 mg/kg hrane (što odgovara maksimalnim vrednostima koje se mogu naći u uzorcima žitarica). Koristili smo larve iz populacije gajene u Institutu za biološka istraživanja „Siniša Stanković“, koje su na početku eksperimenta bile prosečne starosti 2 meseca i prosečne težine 106,2 ± 0,8 mg. Uočeno je da prisustvo mikotoksina u hrani značajno utiče na aktivnost enzima SOD (F(3, 50)=11,738, P<0,001) i GST (F(3,50)=7,889, P<0,001), dok ne dovodi do promene u aktivnosti enzima CAT (F(3, 50)=0,775, P=0,513). Aktivnosti enzima SOD i GST su bile značajno više u grupama larvi gajenih na supstratu sa najnižom (100 µg/kg) i najvišom (10 mg/kg) dozom mikotoksina u odnosu na kontrolne larve gajene na supstratu bez mikotoksina. U grupi larvi gajenih na supstratu sa 2 mg/kg mikotoksina, aktivnost ovih enzima je bila na kontrolnom nivou. Mikotoksin prisutan u hrani utiče i na motorno ponašanje jedinki značajno menjajući pređeni put (H(3,33)=8,739, P<0,05) i vreme provedeno u kretanju (H(3,33)=7,866, P<0,05), dok nema uticaja na prosečnu brzinu tokom kretanja (H(3,33)=5,525, P=0,137). Pređeni put i vreme provedeno u kretanju su bili značajno niži u grupama larvi gajenih na supstratu sa najnižom (100 µg/kg) i najvišom (10 mg/kg) dozom mikotoksina, i nepromenjeni u grupi larvi gajenih na supstratu sa 2 mg/kg mikotoksina, u odnosu na kontrolne larve. Naši rezultati ukazuju da prisustvo mikotoksina ZEA u hrani u dozama od 100 µg/kg i 10 mg/kg dovodi do promena u fiziologiji i ponašanju larvi T. molitor, i to povećanja aktivnosti antioksidativnog i detoksifikacionog enzima praćenog smanjenom motornom aktivnošću. Stoga, analiza ovih lako merljivih i osetljivih parametara može biti važna u ispitivanju i ranom otkrivanju kontaminacije hrane ovim veoma opasnim mikotoksinom.",
publisher = "Belgrade: Entomological Society of Serbia",
journal = "Zbornik rezimea: 13. Simpozijum entomologa Srbije sa međunarodnim učešćem; 2022 Sep 14-16; Pirot, Serbia",
title = "Uticaj mikotoksina zearalenona na aktivnost enzima antioksidativne zaštite i ponašanje larvi Tenebrio molitor (L.)",
pages = "38",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5740"
}

Janković Tomanić, M., Vranković, J., Petković, B.,& Perić Mataruga, V.. (2022). Uticaj mikotoksina zearalenona na aktivnost enzima antioksidativne zaštite i ponašanje larvi Tenebrio molitor (L.). in Zbornik rezimea: 13. Simpozijum entomologa Srbije sa međunarodnim učešćem; 2022 Sep 14-16; Pirot, Serbia
Belgrade: Entomological Society of Serbia., 38.
https://hdl.handle.net/21.15107/rcub_ibiss_5740

Janković Tomanić M, Vranković J, Petković B, Perić Mataruga V. Uticaj mikotoksina zearalenona na aktivnost enzima antioksidativne zaštite i ponašanje larvi Tenebrio molitor (L.). in Zbornik rezimea: 13. Simpozijum entomologa Srbije sa međunarodnim učešćem; 2022 Sep 14-16; Pirot, Serbia. 2022;:38.
https://hdl.handle.net/21.15107/rcub_ibiss_5740 .

Janković Tomanić, Milena, Vranković, Jelena, Petković, Branka, Perić Mataruga, Vesna, "Uticaj mikotoksina zearalenona na aktivnost enzima antioksidativne zaštite i ponašanje larvi Tenebrio molitor (L.)" in Zbornik rezimea: 13. Simpozijum entomologa Srbije sa međunarodnim učešćem; 2022 Sep 14-16; Pirot, Serbia (2022):38,
https://hdl.handle.net/21.15107/rcub_ibiss_5740 .

TY  - JOUR
AU  - Martać, Ljiljana
AU  - Podgorac, Jelena
AU  - Petković, Branka
AU  - Stojadinović, Gordana
PY  - 2022
UR  - https://www.primescholars.com/articles/aluminium-neurotoxicity-and-neuroprotection.pdf
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5736
AB  - Aluminium is considered to be the most widely distributed metal in nature and industry and is extensively used in products and processes associated with human activity. Contamination may occur by air, water, food, additives, medicaments, vaccines, cosmetics, agrochemicals, etc. Aluminium is recognized as a highly neurotoxic element in animals and humans connected with several diseases such as Alzheimer’s and Parkinson’s disease, neurodegenerative motor disorders, encephalopathy, dementia, amyotrophic lateral sclerosis, multiple sclerosis, and autism. There are many animal models in rats developed to investigate aluminium neurotoxicity. Nevertheless, molecular mechanisms of its action are not yet resolved, and mechanisms of damage and safety concentrations are still much discussed. The brain is the most susceptible system to damages provoked by aluminium exposure, such as oxidative stress, iron dyshomeostasis, changes in neurotransmission, immunologic alteration and pro-inflammation, genotoxicity, transformation and peptide denaturation, changes in enzyme activity, membrane perturbation, apoptosis, necrosis, and dysplasia. A novel investigation of aluminium neurotoxicity includes the assessment of neuroprotection and the identification of new substances as potential drugs.
PB  - London: Prime Scholars
T2  - Journal of Heavy Metal Toxicity and Diseases
T1  - Aluminium neurotoxicity and neuroprotection
IS  - 4
VL  - 7
DO  - 10.21767/2473-6457.22.7.4.11
SP  - 11
ER  - 

@article{
author = "Martać, Ljiljana and Podgorac, Jelena and Petković, Branka and Stojadinović, Gordana",
year = "2022",
abstract = "Aluminium is considered to be the most widely distributed metal in nature and industry and is extensively used in products and processes associated with human activity. Contamination may occur by air, water, food, additives, medicaments, vaccines, cosmetics, agrochemicals, etc. Aluminium is recognized as a highly neurotoxic element in animals and humans connected with several diseases such as Alzheimer’s and Parkinson’s disease, neurodegenerative motor disorders, encephalopathy, dementia, amyotrophic lateral sclerosis, multiple sclerosis, and autism. There are many animal models in rats developed to investigate aluminium neurotoxicity. Nevertheless, molecular mechanisms of its action are not yet resolved, and mechanisms of damage and safety concentrations are still much discussed. The brain is the most susceptible system to damages provoked by aluminium exposure, such as oxidative stress, iron dyshomeostasis, changes in neurotransmission, immunologic alteration and pro-inflammation, genotoxicity, transformation and peptide denaturation, changes in enzyme activity, membrane perturbation, apoptosis, necrosis, and dysplasia. A novel investigation of aluminium neurotoxicity includes the assessment of neuroprotection and the identification of new substances as potential drugs.",
publisher = "London: Prime Scholars",
journal = "Journal of Heavy Metal Toxicity and Diseases",
title = "Aluminium neurotoxicity and neuroprotection",
number = "4",
volume = "7",
doi = "10.21767/2473-6457.22.7.4.11",
pages = "11"
}

Martać, L., Podgorac, J., Petković, B.,& Stojadinović, G.. (2022). Aluminium neurotoxicity and neuroprotection. in Journal of Heavy Metal Toxicity and Diseases
London: Prime Scholars., 7(4), 11.
https://doi.org/10.21767/2473-6457.22.7.4.11

Martać L, Podgorac J, Petković B, Stojadinović G. Aluminium neurotoxicity and neuroprotection. in Journal of Heavy Metal Toxicity and Diseases. 2022;7(4):11.
doi:10.21767/2473-6457.22.7.4.11 .

Martać, Ljiljana, Podgorac, Jelena, Petković, Branka, Stojadinović, Gordana, "Aluminium neurotoxicity and neuroprotection" in Journal of Heavy Metal Toxicity and Diseases, 7, no. 4 (2022):11,
https://doi.org/10.21767/2473-6457.22.7.4.11 . .

TY  - CONF
AU  - Vujić, Vukica
AU  - Jovanović, Zvezdana
AU  - Pavković-Lučić, Sofija
AU  - Petković, Branka
AU  - Savić, Tatjana
AU  - Lučić, Luka
AU  - Ilić, Bojan
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5621
AB  - Millipedes (class Diplopoda) represent common members of soil fauna in many ecosystems. They are usually cylindrical or flattened, also characterized by two sets of legs per segment. The relationship between locomotion and morphology has been thoroughly investigated in many arthropods. However, in millipedes, previous studies were mostly based on the influence of different environmental factors on their locomotor activity. The aim of the present study was to analyze the relationship between locomotor activity and morphological variability of body features (body length, body mass), walking legs, and antennae in three European julids, Pachyiulus hungaricus (Karsch, 1881), Megaphyllum unilineatum (C. L. Koch, 1838) and M. bosniense (Verhoeff, 1897). Locomotor activity was videotaped by a web-camera during 15- minute periods and analyzed by ANY-maze software. Antennae and legs were photographed, and their size and shape were estimated using geometric morphometric approach afterwards. Obtained results point out that the evident difference in measured morphological traits among analyzed millipede species significantly determinates their locomotor activity. Moreover, the relationship between locomotor activity and morphological traits is both species-specific and sex-specific.
PB  - Zagreb: Croatian Biological Society
C3  - Book of abstracts: 14th Croatian Biological Congress With International Participation; 2022 Oct 12-16; Pula, Croatia
T1  - Locomotor activity and related morphological traits in three millipede species (Diplopoda: Julida)
SP  - 183
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5621
ER  - 

@conference{
author = "Vujić, Vukica and Jovanović, Zvezdana and Pavković-Lučić, Sofija and Petković, Branka and Savić, Tatjana and Lučić, Luka and Ilić, Bojan",
year = "2022",
abstract = "Millipedes (class Diplopoda) represent common members of soil fauna in many ecosystems. They are usually cylindrical or flattened, also characterized by two sets of legs per segment. The relationship between locomotion and morphology has been thoroughly investigated in many arthropods. However, in millipedes, previous studies were mostly based on the influence of different environmental factors on their locomotor activity. The aim of the present study was to analyze the relationship between locomotor activity and morphological variability of body features (body length, body mass), walking legs, and antennae in three European julids, Pachyiulus hungaricus (Karsch, 1881), Megaphyllum unilineatum (C. L. Koch, 1838) and M. bosniense (Verhoeff, 1897). Locomotor activity was videotaped by a web-camera during 15- minute periods and analyzed by ANY-maze software. Antennae and legs were photographed, and their size and shape were estimated using geometric morphometric approach afterwards. Obtained results point out that the evident difference in measured morphological traits among analyzed millipede species significantly determinates their locomotor activity. Moreover, the relationship between locomotor activity and morphological traits is both species-specific and sex-specific.",
publisher = "Zagreb: Croatian Biological Society",
journal = "Book of abstracts: 14th Croatian Biological Congress With International Participation; 2022 Oct 12-16; Pula, Croatia",
title = "Locomotor activity and related morphological traits in three millipede species (Diplopoda: Julida)",
pages = "183",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5621"
}

Vujić, V., Jovanović, Z., Pavković-Lučić, S., Petković, B., Savić, T., Lučić, L.,& Ilić, B.. (2022). Locomotor activity and related morphological traits in three millipede species (Diplopoda: Julida). in Book of abstracts: 14th Croatian Biological Congress With International Participation; 2022 Oct 12-16; Pula, Croatia
Zagreb: Croatian Biological Society., 183.
https://hdl.handle.net/21.15107/rcub_ibiss_5621

Vujić V, Jovanović Z, Pavković-Lučić S, Petković B, Savić T, Lučić L, Ilić B. Locomotor activity and related morphological traits in three millipede species (Diplopoda: Julida). in Book of abstracts: 14th Croatian Biological Congress With International Participation; 2022 Oct 12-16; Pula, Croatia. 2022;:183.
https://hdl.handle.net/21.15107/rcub_ibiss_5621 .

Vujić, Vukica, Jovanović, Zvezdana, Pavković-Lučić, Sofija, Petković, Branka, Savić, Tatjana, Lučić, Luka, Ilić, Bojan, "Locomotor activity and related morphological traits in three millipede species (Diplopoda: Julida)" in Book of abstracts: 14th Croatian Biological Congress With International Participation; 2022 Oct 12-16; Pula, Croatia (2022):183,
https://hdl.handle.net/21.15107/rcub_ibiss_5621 .

TY  - CONF
AU  - Savić, Tatjana
AU  - Miličić, Dragana
AU  - Drndarski, Marina
AU  - Ninić, Ljiljana
AU  - Pavković-Lučić, Sofija
AU  - Petković, Branka
AU  - Trajković, Jelena
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5620
AB  - Pandemija Kovid-19 uzrokovala je promene u svim sferama života, rada i ponašanja ljudi. U Srbiji, sa izmenjenim načinom rada škola počinje realizacija učenja na daljinu, koja u tom obliku nikada do tada nije primenjivana. U cilju sagledavanja stavova učenika o učenju na daljinu, učenici V-VIII razreda u osnovnim školama iz Beograda i Zaječara su anketirani po principu slučajnosti. Anketirano je ukupno 397 učenika, 216 u Beogradu i 181 u Zaječaru. Anketa je sprovedena anonimno, sa pitanjima višestrukog izbora. Analiza rezultata ankete obuhvatila je odgovore na pitanja koja su se odnosila na: posedovanje ličnog uređaja za praćenje nastave, vreme posvećeno učenju, pomoć nastavnika i postojanje stresa prilikom ovog tipa učenja. Rezultati ankete analizirani su Hi-kvadrat testom (χ2) nezavisnosti.1 Svoj uređaj za praćenje onlajn nastave poseduje 86% učenika iz Beograda i 91% iz Zaječara. Vreme posvećeno učenju u oba grada je od 1- 3 sata dnevno. Za 31% učenika iz Beograda i 45% iz Zaječara nastavnici su bili od pomoći pri učenju na daljinu. Nešto veći procenat učenika iz Zaječara (34%) u odnosu na Beograd (30%) se izjasnio da im učenje na daljinu nije stresno uopšte. Rezultati ovog istraživanja doprinose razumevanju pojedinih aspekata učenja na daljinu tokom pandemije. 1. Scott, A.J., Rao, J.N.K., 1981, Chi-squared tests for contingency tables with proportions estimated from survey data, in: D. Krewski, R. Platek, J.N.K. Rao (eds.) Current Topics in Survey Sampling, pp. 247-265, Elsevier Inc., Amsterdam.
AB  - Пандемија Kовид-19 узроковала је промене у свим сферама живота, рада и
понашања људи. У Србији, са измењеним начином рада школа почиње реализација
учења на даљину, која у том облику никада до тада није примењивана. У циљу
сагледавања ставова ученика о учењу на даљину, ученици V-VIII разреда у
основним школама из Београда и Зајечара су анкетирани по принципу случајности.
Анкетирано је укупно 397 ученика, 216 у Београду и 181 у Зајечару. Анкета је
спроведена анонимно, са питањима вишеструког избора. Анализа резултата анкете
обухватила је одговоре на питања која су се односила на: поседовање личног
уређаја за праћење наставе, време посвећено учењу, помоћ наставника и постојање
стреса приликом овог типа учења. Резултати анкете анализирани су Хи-квадрат
тестом (χ2) независности.1 Свој уређај за праћење онлајн наставе поседује 86%
ученика из Београда и 91% из Зајечара. Време посвећено учењу у оба града је од 1-
3 сата дневно. За 31% ученика из Београда и 45% из Зајечара наставници су били
од помоћи при учењу на даљину. Нешто већи проценат ученика из Зајечара (34%) у
односу на Београд (30%) се изјаснио да им учење на даљину није стресно уопште.
Резултати овог истраживања доприносе разумевању појединих аспеката учења на
даљину током пандемије.
PB  - Belgrade: Serbian Biological Society
C3  - Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia
T1  - Stavovi učenika osnovnih škola iz dve gradske sredine u Srbiji o učenju na daljinu tokom pandemije SARS-CoV-2 virusa
T1  - Ставови ученика основних школа из две градске средине у Србији о учењу на даљину током пандемије SARS-CoV-2 вируса
SP  - 215
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5620
ER  - 

@conference{
author = "Savić, Tatjana and Miličić, Dragana and Drndarski, Marina and Ninić, Ljiljana and Pavković-Lučić, Sofija and Petković, Branka and Trajković, Jelena",
year = "2022",
abstract = "Pandemija Kovid-19 uzrokovala je promene u svim sferama života, rada i ponašanja ljudi. U Srbiji, sa izmenjenim načinom rada škola počinje realizacija učenja na daljinu, koja u tom obliku nikada do tada nije primenjivana. U cilju sagledavanja stavova učenika o učenju na daljinu, učenici V-VIII razreda u osnovnim školama iz Beograda i Zaječara su anketirani po principu slučajnosti. Anketirano je ukupno 397 učenika, 216 u Beogradu i 181 u Zaječaru. Anketa je sprovedena anonimno, sa pitanjima višestrukog izbora. Analiza rezultata ankete obuhvatila je odgovore na pitanja koja su se odnosila na: posedovanje ličnog uređaja za praćenje nastave, vreme posvećeno učenju, pomoć nastavnika i postojanje stresa prilikom ovog tipa učenja. Rezultati ankete analizirani su Hi-kvadrat testom (χ2) nezavisnosti.1 Svoj uređaj za praćenje onlajn nastave poseduje 86% učenika iz Beograda i 91% iz Zaječara. Vreme posvećeno učenju u oba grada je od 1- 3 sata dnevno. Za 31% učenika iz Beograda i 45% iz Zaječara nastavnici su bili od pomoći pri učenju na daljinu. Nešto veći procenat učenika iz Zaječara (34%) u odnosu na Beograd (30%) se izjasnio da im učenje na daljinu nije stresno uopšte. Rezultati ovog istraživanja doprinose razumevanju pojedinih aspekata učenja na daljinu tokom pandemije. 1. Scott, A.J., Rao, J.N.K., 1981, Chi-squared tests for contingency tables with proportions estimated from survey data, in: D. Krewski, R. Platek, J.N.K. Rao (eds.) Current Topics in Survey Sampling, pp. 247-265, Elsevier Inc., Amsterdam., Пандемија Kовид-19 узроковала је промене у свим сферама живота, рада и
понашања људи. У Србији, са измењеним начином рада школа почиње реализација
учења на даљину, која у том облику никада до тада није примењивана. У циљу
сагледавања ставова ученика о учењу на даљину, ученици V-VIII разреда у
основним школама из Београда и Зајечара су анкетирани по принципу случајности.
Анкетирано је укупно 397 ученика, 216 у Београду и 181 у Зајечару. Анкета је
спроведена анонимно, са питањима вишеструког избора. Анализа резултата анкете
обухватила је одговоре на питања која су се односила на: поседовање личног
уређаја за праћење наставе, време посвећено учењу, помоћ наставника и постојање
стреса приликом овог типа учења. Резултати анкете анализирани су Хи-квадрат
тестом (χ2) независности.1 Свој уређај за праћење онлајн наставе поседује 86%
ученика из Београда и 91% из Зајечара. Време посвећено учењу у оба града је од 1-
3 сата дневно. За 31% ученика из Београда и 45% из Зајечара наставници су били
од помоћи при учењу на даљину. Нешто већи проценат ученика из Зајечара (34%) у
односу на Београд (30%) се изјаснио да им учење на даљину није стресно уопште.
Резултати овог истраживања доприносе разумевању појединих аспеката учења на
даљину током пандемије.",
publisher = "Belgrade: Serbian Biological Society",
journal = "Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia",
title = "Stavovi učenika osnovnih škola iz dve gradske sredine u Srbiji o učenju na daljinu tokom pandemije SARS-CoV-2 virusa, Ставови ученика основних школа из две градске средине у Србији о учењу на даљину током пандемије SARS-CoV-2 вируса",
pages = "215",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5620"
}

Savić, T., Miličić, D., Drndarski, M., Ninić, L., Pavković-Lučić, S., Petković, B.,& Trajković, J.. (2022). Stavovi učenika osnovnih škola iz dve gradske sredine u Srbiji o učenju na daljinu tokom pandemije SARS-CoV-2 virusa. in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia
Belgrade: Serbian Biological Society., 215.
https://hdl.handle.net/21.15107/rcub_ibiss_5620

Savić T, Miličić D, Drndarski M, Ninić L, Pavković-Lučić S, Petković B, Trajković J. Stavovi učenika osnovnih škola iz dve gradske sredine u Srbiji o učenju na daljinu tokom pandemije SARS-CoV-2 virusa. in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia. 2022;:215.
https://hdl.handle.net/21.15107/rcub_ibiss_5620 .

Savić, Tatjana, Miličić, Dragana, Drndarski, Marina, Ninić, Ljiljana, Pavković-Lučić, Sofija, Petković, Branka, Trajković, Jelena, "Stavovi učenika osnovnih škola iz dve gradske sredine u Srbiji o učenju na daljinu tokom pandemije SARS-CoV-2 virusa" in Knjiga sažetaka: Treći Kongres biologa Srbije: Osnovna i primenjena istraživanja: Metodika nastave; 2022 Sep 21-25; Zlatibor, Serbia (2022):215,
https://hdl.handle.net/21.15107/rcub_ibiss_5620 .

TY  - CONF
AU  - Nikolić, Ljiljana
AU  - Savić, Danijela
AU  - Korać Jačić, Jelena
AU  - Petković, Branka
AU  - Stojadinović, Gordana
AU  - Martać, Ljiljana
AU  - Bogdanović Pristov, Jelena
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5509
AB  - Living cells exhibit multiple ion channel proteins and malfunction of these channels underlies
numerous diseases. Channelopathies include diseases of the nervous, cardiovascular, respiratory,
endocrine, urinary, and immune system. Currently, ion channels represent the second-largest target
for existing drugs. Here, using the whole-cell patch-clamp technique, we explored the epinephrine
effect on membrane ionic currents in glioma C6 cells. We demonstrate that epinephrine specifically
evokes an increase of C6 cells outward ionic currents that is stable within 10 min, while it does not
affect inward currents. Our results thus provide fine resolution and time frame for targeting ion
channel activity that is crucial in pharmacological investigations.
PB  - Belgrade: Society of Physical Chemists of Serbia
C3  - Proceedings: Physical Chemistry 2022, Vol. 2.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia
T1  - Membrane currents of C6 cells in pharmacological investigation
SP  - 589
EP  - 592
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5509
ER  - 

@conference{
author = "Nikolić, Ljiljana and Savić, Danijela and Korać Jačić, Jelena and Petković, Branka and Stojadinović, Gordana and Martać, Ljiljana and Bogdanović Pristov, Jelena",
year = "2022",
abstract = "Living cells exhibit multiple ion channel proteins and malfunction of these channels underlies
numerous diseases. Channelopathies include diseases of the nervous, cardiovascular, respiratory,
endocrine, urinary, and immune system. Currently, ion channels represent the second-largest target
for existing drugs. Here, using the whole-cell patch-clamp technique, we explored the epinephrine
effect on membrane ionic currents in glioma C6 cells. We demonstrate that epinephrine specifically
evokes an increase of C6 cells outward ionic currents that is stable within 10 min, while it does not
affect inward currents. Our results thus provide fine resolution and time frame for targeting ion
channel activity that is crucial in pharmacological investigations.",
publisher = "Belgrade: Society of Physical Chemists of Serbia",
journal = "Proceedings: Physical Chemistry 2022, Vol. 2.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia",
title = "Membrane currents of C6 cells in pharmacological investigation",
pages = "589-592",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5509"
}

Nikolić, L., Savić, D., Korać Jačić, J., Petković, B., Stojadinović, G., Martać, L.,& Bogdanović Pristov, J.. (2022). Membrane currents of C6 cells in pharmacological investigation. in Proceedings: Physical Chemistry 2022, Vol. 2.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia
Belgrade: Society of Physical Chemists of Serbia., 589-592.
https://hdl.handle.net/21.15107/rcub_ibiss_5509

Nikolić L, Savić D, Korać Jačić J, Petković B, Stojadinović G, Martać L, Bogdanović Pristov J. Membrane currents of C6 cells in pharmacological investigation. in Proceedings: Physical Chemistry 2022, Vol. 2.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia. 2022;:589-592.
https://hdl.handle.net/21.15107/rcub_ibiss_5509 .

Nikolić, Ljiljana, Savić, Danijela, Korać Jačić, Jelena, Petković, Branka, Stojadinović, Gordana, Martać, Ljiljana, Bogdanović Pristov, Jelena, "Membrane currents of C6 cells in pharmacological investigation" in Proceedings: Physical Chemistry 2022, Vol. 2.: 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry; 2022 Sep 26-30; Belgrade, Serbia (2022):589-592,
https://hdl.handle.net/21.15107/rcub_ibiss_5509 .

TY  - CONF
AU  - Todorović, Dajana
AU  - Ilijin, Larisa
AU  - Vlahović, Milena
AU  - Mrdaković, Marija
AU  - Petković, Branka
AU  - Matić, Dragana
AU  - Grčić, Anja
AU  - Filipović, Aleksandra
AU  - Perić Mataruga, Vesna
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5313
AB  - Magnetic fields are all around us: in the Universe, on the Earth, among and within organisms, cells, molecules, and single atoms. Fast technological development and modernization of life, increase the level of artificial magnetic fields, thus affecting every living beings. Hence, exposure of organisms to omnipresent magnetic field could represent important stressogenic factor for them. Magnetic sensitivity is very well documented in insects, but there is little research of the effects of magnetic fields on antioxidative defense during their development. The main purpose of this work was to evaluate the effects of static magnetic field (SMF, 230 mT) on antioxidative defense, as well as life history traits of larval instars (from 1st to 4th) of Lymantria dispar L. (Lepidoptera). The activity of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), and glutathione-S transferase (GST) in each larval instar was measured spectrophotometrically. Life history traits (mortality, larval mass and development duration) were monitored daily. Magnetic field increased the activity of SOD, CAT, GR, and GST in all larval instars, but these changes were significant only in older larval instars (3rd and 4th), except CAT. During the larval development, mortality was higher in SMF group than the control. Also, we observed a significant increase in mass of 4th larval instar in magnetic field compared to the control. On the other hand, we did not detect a significant influence of SMF on duration of larval instars. The obtained results demonstrate differences in MF susceptibility of younger and older larval instars of L. dispar. In conclusion, the applied magnetic field could be considered as a potential stressor influencing life history traits, as well as examined antioxidative biomarkers.
PB  - Niš: RAD Centre
C3  - Book of abstracts:10th Jubilee International Conference on Radiation in Various Fields of Research: RAD 2022; 2022 Jul 25-29; Herceg Novi, Montenegro
T1  - Antioxidative defense and life history traits of four larval instars of Lymantria dispar L. in static magnetic field
SP  - 2
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5313
ER  - 

@conference{
author = "Todorović, Dajana and Ilijin, Larisa and Vlahović, Milena and Mrdaković, Marija and Petković, Branka and Matić, Dragana and Grčić, Anja and Filipović, Aleksandra and Perić Mataruga, Vesna",
year = "2022",
abstract = "Magnetic fields are all around us: in the Universe, on the Earth, among and within organisms, cells, molecules, and single atoms. Fast technological development and modernization of life, increase the level of artificial magnetic fields, thus affecting every living beings. Hence, exposure of organisms to omnipresent magnetic field could represent important stressogenic factor for them. Magnetic sensitivity is very well documented in insects, but there is little research of the effects of magnetic fields on antioxidative defense during their development. The main purpose of this work was to evaluate the effects of static magnetic field (SMF, 230 mT) on antioxidative defense, as well as life history traits of larval instars (from 1st to 4th) of Lymantria dispar L. (Lepidoptera). The activity of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), and glutathione-S transferase (GST) in each larval instar was measured spectrophotometrically. Life history traits (mortality, larval mass and development duration) were monitored daily. Magnetic field increased the activity of SOD, CAT, GR, and GST in all larval instars, but these changes were significant only in older larval instars (3rd and 4th), except CAT. During the larval development, mortality was higher in SMF group than the control. Also, we observed a significant increase in mass of 4th larval instar in magnetic field compared to the control. On the other hand, we did not detect a significant influence of SMF on duration of larval instars. The obtained results demonstrate differences in MF susceptibility of younger and older larval instars of L. dispar. In conclusion, the applied magnetic field could be considered as a potential stressor influencing life history traits, as well as examined antioxidative biomarkers.",
publisher = "Niš: RAD Centre",
journal = "Book of abstracts:10th Jubilee International Conference on Radiation in Various Fields of Research: RAD 2022; 2022 Jul 25-29; Herceg Novi, Montenegro",
title = "Antioxidative defense and life history traits of four larval instars of Lymantria dispar L. in static magnetic field",
pages = "2",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5313"
}

Todorović, D., Ilijin, L., Vlahović, M., Mrdaković, M., Petković, B., Matić, D., Grčić, A., Filipović, A.,& Perić Mataruga, V.. (2022). Antioxidative defense and life history traits of four larval instars of Lymantria dispar L. in static magnetic field. in Book of abstracts:10th Jubilee International Conference on Radiation in Various Fields of Research: RAD 2022; 2022 Jul 25-29; Herceg Novi, Montenegro
Niš: RAD Centre., 2.
https://hdl.handle.net/21.15107/rcub_ibiss_5313

Todorović D, Ilijin L, Vlahović M, Mrdaković M, Petković B, Matić D, Grčić A, Filipović A, Perić Mataruga V. Antioxidative defense and life history traits of four larval instars of Lymantria dispar L. in static magnetic field. in Book of abstracts:10th Jubilee International Conference on Radiation in Various Fields of Research: RAD 2022; 2022 Jul 25-29; Herceg Novi, Montenegro. 2022;:2.
https://hdl.handle.net/21.15107/rcub_ibiss_5313 .

Todorović, Dajana, Ilijin, Larisa, Vlahović, Milena, Mrdaković, Marija, Petković, Branka, Matić, Dragana, Grčić, Anja, Filipović, Aleksandra, Perić Mataruga, Vesna, "Antioxidative defense and life history traits of four larval instars of Lymantria dispar L. in static magnetic field" in Book of abstracts:10th Jubilee International Conference on Radiation in Various Fields of Research: RAD 2022; 2022 Jul 25-29; Herceg Novi, Montenegro (2022):2,
https://hdl.handle.net/21.15107/rcub_ibiss_5313 .

TY  - JOUR
AU  - Ilić, Đorđe
AU  - Ilić, Aleksandra
AU  - Jakovljević, Branislava
AU  - Džigurski, Jelisaveta
AU  - Dragić, Nataša
AU  - Simić, Svetlana
AU  - Petković, Branka
AU  - Sekulić, Slobodan
PY  - 2021
UR  - https://www.arccjournals.com/journal/indian-journal-of-animal-research/B-1319
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4428
AB  - A review was conducted using PubMed/MEDLINE (published articles) as well as World Wide Web (video material) to determine the frequency of anterior and posterior presentation of the elephant at birth. Of 46 identified cases, 12 were in anterior and 34 in posterior presentation. The Fisher exact test (p= 0.682) did not show a statistically significant difference in the distribution of presentations between the Loxodonta africana (2 anterior and 10 posterior presentation) and Elephas maximus (10 anterior and 24 posterior presentation). The ratio between anterior and posterior presentation 6:29 (18.51% versus 81.49%) at birth without knowing dystocia, is significantly different from the distribution anterior and posterior presentation 6:3 (66.7% versus 33.3%) in cases with dystocia (Fisher exact test p = 0.012). Obtained data shows that posterior presentation at birth in elephants is more often present than anterior, while anterior presentation is more often associated with dystocia.
PB  - Karnal : Agricultural Research Communication Centre
T2  - Indian Journal of Animal Research
T1  - The Incidence of Anterior and Posterior Presentation at Birth in Asian (Elephas maximus) and African Elephants (Loxodonta africana): A Review Study
IS  - 8
VL  - 55
DO  - 10.18805/IJAR.B-1319
SP  - 863
EP  - 866
ER  - 

@article{
author = "Ilić, Đorđe and Ilić, Aleksandra and Jakovljević, Branislava and Džigurski, Jelisaveta and Dragić, Nataša and Simić, Svetlana and Petković, Branka and Sekulić, Slobodan",
year = "2021",
abstract = "A review was conducted using PubMed/MEDLINE (published articles) as well as World Wide Web (video material) to determine the frequency of anterior and posterior presentation of the elephant at birth. Of 46 identified cases, 12 were in anterior and 34 in posterior presentation. The Fisher exact test (p= 0.682) did not show a statistically significant difference in the distribution of presentations between the Loxodonta africana (2 anterior and 10 posterior presentation) and Elephas maximus (10 anterior and 24 posterior presentation). The ratio between anterior and posterior presentation 6:29 (18.51% versus 81.49%) at birth without knowing dystocia, is significantly different from the distribution anterior and posterior presentation 6:3 (66.7% versus 33.3%) in cases with dystocia (Fisher exact test p = 0.012). Obtained data shows that posterior presentation at birth in elephants is more often present than anterior, while anterior presentation is more often associated with dystocia.",
publisher = "Karnal : Agricultural Research Communication Centre",
journal = "Indian Journal of Animal Research",
title = "The Incidence of Anterior and Posterior Presentation at Birth in Asian (Elephas maximus) and African Elephants (Loxodonta africana): A Review Study",
number = "8",
volume = "55",
doi = "10.18805/IJAR.B-1319",
pages = "863-866"
}

Ilić, Đ., Ilić, A., Jakovljević, B., Džigurski, J., Dragić, N., Simić, S., Petković, B.,& Sekulić, S.. (2021). The Incidence of Anterior and Posterior Presentation at Birth in Asian (Elephas maximus) and African Elephants (Loxodonta africana): A Review Study. in Indian Journal of Animal Research
Karnal : Agricultural Research Communication Centre., 55(8), 863-866.
https://doi.org/10.18805/IJAR.B-1319

Ilić Đ, Ilić A, Jakovljević B, Džigurski J, Dragić N, Simić S, Petković B, Sekulić S. The Incidence of Anterior and Posterior Presentation at Birth in Asian (Elephas maximus) and African Elephants (Loxodonta africana): A Review Study. in Indian Journal of Animal Research. 2021;55(8):863-866.
doi:10.18805/IJAR.B-1319 .

Ilić, Đorđe, Ilić, Aleksandra, Jakovljević, Branislava, Džigurski, Jelisaveta, Dragić, Nataša, Simić, Svetlana, Petković, Branka, Sekulić, Slobodan, "The Incidence of Anterior and Posterior Presentation at Birth in Asian (Elephas maximus) and African Elephants (Loxodonta africana): A Review Study" in Indian Journal of Animal Research, 55, no. 8 (2021):863-866,
https://doi.org/10.18805/IJAR.B-1319 . .

TY  - JOUR
AU  - Sekulić, Slobodan
AU  - Lemajić-Komazec, Slobodanka
AU  - Sokolovac, Ivana
AU  - Topalidou, Anastasia
AU  - Gouni, Olga
AU  - Petković, Branka
AU  - Martać, Ljiljana
AU  - Keković, Goran
AU  - Redžek-Mudrinić, Tatjana
AU  - Čapo, Ivan
PY  - 2021
UR  - http://www.ncbi.nlm.nih.gov/pubmed/32159401
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3635
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/4772
AB  - Background: There is speculation that an immature vestibular system may be associated with breech presentation at delivery. Our aim was to determine whether syndromes with congenital inner ear malformations were accompanied by a higher frequency of breech presentation/malpresentations than in the general population (2%-3%). Methods: A review was conducted for published literature using PubMed/MEDLINE (1936-2016), to determine frequency of breech presentation and transverse lie in cases with congenital deafness (Michel aplasia, Wildervanck syndrome, Mondini-Alexander dysplasia, Waardenburg syndrome, CHARGE syndrome, Large vestibular aqueductal syndrome, Pendred syndrome, Oculo-aurico-vertebral spectrum, Jervel and Lange-Nielsen syndrome, Usher syndrome, and Scheibe dysplasia) and vestibular nerve aplasia. Results: Identified were total of 122 cases. The frequency of breech presentation was 1.64%, and of transverse lie 1.64%, giving a total of 3.28% malpresentations. Conclusion: The results of the study suggest that congenital malformations of the vestibular apparatus are not associated with the increased risk of breech presentation at delivery.
PB  - Taylor and Francis Ltd
T2  - Fetal and Pediatric Pathology
T1  - Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation
IS  - 6
VL  - 40
DO  - 10.1080/15513815.2020.1737993
SP  - 674
EP  - 684
ER  - 

@article{
author = "Sekulić, Slobodan and Lemajić-Komazec, Slobodanka and Sokolovac, Ivana and Topalidou, Anastasia and Gouni, Olga and Petković, Branka and Martać, Ljiljana and Keković, Goran and Redžek-Mudrinić, Tatjana and Čapo, Ivan",
year = "2021",
abstract = "Background: There is speculation that an immature vestibular system may be associated with breech presentation at delivery. Our aim was to determine whether syndromes with congenital inner ear malformations were accompanied by a higher frequency of breech presentation/malpresentations than in the general population (2%-3%). Methods: A review was conducted for published literature using PubMed/MEDLINE (1936-2016), to determine frequency of breech presentation and transverse lie in cases with congenital deafness (Michel aplasia, Wildervanck syndrome, Mondini-Alexander dysplasia, Waardenburg syndrome, CHARGE syndrome, Large vestibular aqueductal syndrome, Pendred syndrome, Oculo-aurico-vertebral spectrum, Jervel and Lange-Nielsen syndrome, Usher syndrome, and Scheibe dysplasia) and vestibular nerve aplasia. Results: Identified were total of 122 cases. The frequency of breech presentation was 1.64%, and of transverse lie 1.64%, giving a total of 3.28% malpresentations. Conclusion: The results of the study suggest that congenital malformations of the vestibular apparatus are not associated with the increased risk of breech presentation at delivery.",
publisher = "Taylor and Francis Ltd",
journal = "Fetal and Pediatric Pathology",
title = "Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation",
number = "6",
volume = "40",
doi = "10.1080/15513815.2020.1737993",
pages = "674-684"
}

Sekulić, S., Lemajić-Komazec, S., Sokolovac, I., Topalidou, A., Gouni, O., Petković, B., Martać, L., Keković, G., Redžek-Mudrinić, T.,& Čapo, I.. (2021). Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation. in Fetal and Pediatric Pathology
Taylor and Francis Ltd., 40(6), 674-684.
https://doi.org/10.1080/15513815.2020.1737993

Sekulić S, Lemajić-Komazec S, Sokolovac I, Topalidou A, Gouni O, Petković B, Martać L, Keković G, Redžek-Mudrinić T, Čapo I. Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation. in Fetal and Pediatric Pathology. 2021;40(6):674-684.
doi:10.1080/15513815.2020.1737993 .

Sekulić, Slobodan, Lemajić-Komazec, Slobodanka, Sokolovac, Ivana, Topalidou, Anastasia, Gouni, Olga, Petković, Branka, Martać, Ljiljana, Keković, Goran, Redžek-Mudrinić, Tatjana, Čapo, Ivan, "Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation" in Fetal and Pediatric Pathology, 40, no. 6 (2021):674-684,
https://doi.org/10.1080/15513815.2020.1737993 . .

TY  - JOUR
AU  - Sekulić, Slobodan
AU  - Lemajić-Komazec, Slobodanka
AU  - Sokolovac, Ivana
AU  - Topalidou, Anastasia
AU  - Gouni, Olga
AU  - Petković, Branka
AU  - Martać, Ljiljana
AU  - Keković, Goran
AU  - Redžek-Mudrinić, Tatjana
AU  - Čapo, Ivan
PY  - 2021
UR  - http://www.ncbi.nlm.nih.gov/pubmed/32159401
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3635
AB  - Background: There is speculation that an immature vestibular system may be associated with breech presentation at delivery. Our aim was to determine whether syndromes with congenital inner ear malformations were accompanied by a higher frequency of breech presentation/malpresentations than in the general population (2%-3%). Methods: A review was conducted for published literature using PubMed/MEDLINE (1936-2016), to determine frequency of breech presentation and transverse lie in cases with congenital deafness (Michel aplasia, Wildervanck syndrome, Mondini-Alexander dysplasia, Waardenburg syndrome, CHARGE syndrome, Large vestibular aqueductal syndrome, Pendred syndrome, Oculo-aurico-vertebral spectrum, Jervel and Lange-Nielsen syndrome, Usher syndrome, and Scheibe dysplasia) and vestibular nerve aplasia. Results: Identified were total of 122 cases. The frequency of breech presentation was 1.64%, and of transverse lie 1.64%, giving a total of 3.28% malpresentations. Conclusion: The results of the study suggest that congenital malformations of the vestibular apparatus are not associated with the increased risk of breech presentation at delivery.
PB  - Taylor and Francis Ltd
T2  - Fetal and Pediatric Pathology
T1  - Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation
IS  - 6
VL  - 40
DO  - 10.1080/15513815.2020.1737993
SP  - 674
EP  - 684
ER  - 

@article{
author = "Sekulić, Slobodan and Lemajić-Komazec, Slobodanka and Sokolovac, Ivana and Topalidou, Anastasia and Gouni, Olga and Petković, Branka and Martać, Ljiljana and Keković, Goran and Redžek-Mudrinić, Tatjana and Čapo, Ivan",
year = "2021",
abstract = "Background: There is speculation that an immature vestibular system may be associated with breech presentation at delivery. Our aim was to determine whether syndromes with congenital inner ear malformations were accompanied by a higher frequency of breech presentation/malpresentations than in the general population (2%-3%). Methods: A review was conducted for published literature using PubMed/MEDLINE (1936-2016), to determine frequency of breech presentation and transverse lie in cases with congenital deafness (Michel aplasia, Wildervanck syndrome, Mondini-Alexander dysplasia, Waardenburg syndrome, CHARGE syndrome, Large vestibular aqueductal syndrome, Pendred syndrome, Oculo-aurico-vertebral spectrum, Jervel and Lange-Nielsen syndrome, Usher syndrome, and Scheibe dysplasia) and vestibular nerve aplasia. Results: Identified were total of 122 cases. The frequency of breech presentation was 1.64%, and of transverse lie 1.64%, giving a total of 3.28% malpresentations. Conclusion: The results of the study suggest that congenital malformations of the vestibular apparatus are not associated with the increased risk of breech presentation at delivery.",
publisher = "Taylor and Francis Ltd",
journal = "Fetal and Pediatric Pathology",
title = "Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation",
number = "6",
volume = "40",
doi = "10.1080/15513815.2020.1737993",
pages = "674-684"
}

Sekulić, S., Lemajić-Komazec, S., Sokolovac, I., Topalidou, A., Gouni, O., Petković, B., Martać, L., Keković, G., Redžek-Mudrinić, T.,& Čapo, I.. (2021). Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation. in Fetal and Pediatric Pathology
Taylor and Francis Ltd., 40(6), 674-684.
https://doi.org/10.1080/15513815.2020.1737993

Sekulić S, Lemajić-Komazec S, Sokolovac I, Topalidou A, Gouni O, Petković B, Martać L, Keković G, Redžek-Mudrinić T, Čapo I. Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation. in Fetal and Pediatric Pathology. 2021;40(6):674-684.
doi:10.1080/15513815.2020.1737993 .

Sekulić, Slobodan, Lemajić-Komazec, Slobodanka, Sokolovac, Ivana, Topalidou, Anastasia, Gouni, Olga, Petković, Branka, Martać, Ljiljana, Keković, Goran, Redžek-Mudrinić, Tatjana, Čapo, Ivan, "Inner Ear Malformations in Congenital Deafness Are Not Associated with Increased Risk of Breech Presentation" in Fetal and Pediatric Pathology, 40, no. 6 (2021):674-684,
https://doi.org/10.1080/15513815.2020.1737993 . .